Aliases for HLA-E Gene
Aliases for HLA-E Gene
External Ids for HLA-E Gene
- HGNC: 4962
- Entrez Gene: 3133
- Ensembl: ENSG00000204592
- OMIM: 143010
- UniProtKB: P13747
Previous GeneCards Identifiers for HLA-E Gene
- GC06P030513
- GC06P030228
- GC06P030563
- GC06P030565
- GC06P030457
- GC06P030257
- GC06P030491
- GC06P030635
- GC06P030657
- GC06P030764
Summaries for HLA-E Gene
-
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008]
GeneCards Summary for HLA-E Gene
HLA-E (Major Histocompatibility Complex, Class I, E) is a Protein Coding gene. Diseases associated with HLA-E include Hematopoietic Stem Cell Transplantation. Among its related pathways are Allograft rejection and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. GO annotations related to this gene include receptor binding and MHC class I protein binding. An important paralog of this gene is HLA-A.
UniProtKB/Swiss-Prot for HLA-E Gene
-
Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HLA-E Gene
Genomics for HLA-E Gene
Regulatory Elements for HLA-E Gene
Enhancers for HLA-E Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HLA-E on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the HLA-E gene promoter:
Regulatory Element Products
Genomic Location for HLA-E Gene
- Chromosome:
- 6
- Start:
- 30,489,406 bp from pter
- End:
- 30,494,205 bp from pter
- Size:
- 4,800 bases
- Orientation:
- Plus strand
Genomic View for HLA-E Gene
Genes around HLA-E on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.1 by Ensembl
- 6p22.1 by Entrez Gene
- 6p22.1 by HGNC
HLA-E Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HLA-E Gene
Proteins for HLA-E Gene
-
Protein details for HLA-E Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P13747-HLAE_HUMAN
- Recommended name:
- HLA class I histocompatibility antigen, alpha chain E
- Protein Accession:
- P13747
- Q30169
- Q9BT83
- Q9GIY7
- Q9GIY8
Protein attributes for HLA-E Gene
- Size:
- 358 amino acids
- Molecular mass:
- 40157 Da
- Quaternary structure:
-
- Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin).
Protein Expression for HLA-E Gene
Post-translational modifications for HLA-E Gene
Other Protein References for HLA-E Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for HLA-E
- Novus Biologicals Antibodies for HLA-E
-
Abcam antibodies for HLA-E
-
Cloud-Clone Corp. Antibodies for HLA-E
- Invitrogen Antibodies for HLA-E
- antibodies-online Antibodies for HLA-E: See all 107
- GeneTex HLA-E antibody for HLA-E
-
Santa Cruz Biotechnology (SCBT) Antibodies for HLA-E
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HLA-E
- Origene Custom Protein Services for HLA-E
-
Cloud-Clone Corp. Proteins for HLA-E
- antibodies-online Proteins for HLA-E: See all 6
- Search antibodies-online for peptides
- Search GeneTex for Proteins for HLA-E
-
Abcam proteins for HLA-E
No data available for DME Specific Peptides for HLA-E Gene
Domains & Families for HLA-E Gene
Gene Families for HLA-E Gene
Protein Domains for HLA-E Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for HLA-E Gene
Graphical View of Domain Structure for InterPro Entry
P13747- Family:
-
- Belongs to the MHC class I family.
Function for HLA-E Gene
Molecular function for HLA-E Gene
- GENATLAS Biochemistry:
- HLA class Ib,44kDa,6.2kb HindIII fragment,TAP and tapasin dependent,localized at the cell surface,harboring structural features conferring tight peptide binding specificity,correlating with the binding of an MHC class I leader peptide (see MHC1)
- UniProtKB/Swiss-Prot Function:
- Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005102 | receptor binding | IPI | 18448674 |
| GO:0030881 | beta-2-microglobulin binding | IMP | 12411439 |
| GO:0042288 | MHC class I protein binding | IDA | 9754572 |
| GO:0042605 | peptide antigen binding | IMP | 12411439 |
| GO:0042608 | T cell receptor binding | IDA | 16474394 |
Phenotypes for HLA-E Gene
- GenomeRNAi human phenotypes for HLA-E:
-
- Increased shRNA abundance (Z-score > 2)
- Decreased viability ratio
- Dynamic nuclei (hole, folded or small irregular)
- Decreased human papilloma virus 16 (HPV16) pseudovirus infection
- Increased transferrin (TF) endocytosis
- Decreased shRNA abundance (Z-score < -2)
- Increased shRNA abundance
- Decreased interferon-beta reporter expression
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences ready-to-package AAV shRNAs for HLA-E gene
- Search ViGene Biosciences for HLA-E
CRISPR Products
- Browse CRISPR knockouts for HLA-E
-
Santa Cruz Biotechnology (SCBT) CRISPR for HLA-E
- GenScript: Design CRISPR guide RNA sequences for HLA-E
miRNA for HLA-E Gene
- miRTarBase miRNAs that target HLA-E
-
- hsa-mir-296-3p (MIRT038407)
- hsa-mir-92a-3p (MIRT049514)
- hsa-mir-218-5p (MIRT440496)
- hsa-mir-455-3p (MIRT618767)
- hsa-mir-143-5p (MIRT618768)
- hsa-mir-6879-3p (MIRT618769)
- hsa-mir-4430 (MIRT618770)
- hsa-mir-3652 (MIRT618771)
- hsa-mir-122-5p (MIRT618772)
- hsa-mir-504-3p (MIRT618773)
- hsa-mir-3135b (MIRT618774)
- hsa-mir-6773-3p (MIRT618775)
- hsa-mir-339-5p (MIRT618776)
- hsa-mir-3620-3p (MIRT618777)
- hsa-mir-500b-3p (MIRT618778)
- hsa-mir-10b-5p (MIRT618779)
- hsa-mir-10a-5p (MIRT618780)
- hsa-mir-6770-5p (MIRT722045)
- hsa-mir-6126 (MIRT722046)
- hsa-mir-4493 (MIRT722047)
- hsa-mir-605-3p (MIRT722048)
- hsa-mir-5582-5p (MIRT722049)
- hsa-mir-124-3p (MIRT722051)
miRNA Products
- Search ViGene Biosciences for HLA-E
Inhibitory RNA Products
-
ViGene Biosciences ready-to-package AAV shRNAs for HLA-E gene
Clone Products
- Sino Biological Human cDNA Clone for HLA-E
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for HLA-E
-
ViGene Biosciences adenoviral particle packaged cDNA for HLA-E gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HLA-E gene
- Search ViGene Biosciences for HLA-E
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HLA-E Gene
Localization for HLA-E Gene
Subcellular locations from UniProtKB/Swiss-Prot for HLA-E Gene
- Membrane; Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| endoplasmic reticulum | 5 |
| golgi apparatus | 5 |
| endosome | 4 |
| cytosol | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| nucleus | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0009986 | cell surface | IDA | 9754572 |
| GO:0012507 | ER to Golgi transport vesicle membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
Pathways & Interactions for HLA-E Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Allograft rejection | ||
| 2 | Immune response Role of DAP12 receptors in NK cells | ||
| 3 | Antigen processing-Cross presentation | ||
| 4 | Class I MHC mediated antigen processing and presentation | ||
| 5 | RET signaling |
.92
|
|
Pathways by source for HLA-E Gene
1 Sino Biological pathway for HLA-E Gene
2 BioSystems pathways for HLA-E Gene
15 Reactome pathways for HLA-E Gene
14 KEGG pathways for HLA-E Gene
3 GeneGo (Thomson Reuters) pathways for HLA-E Gene
1 R&D Systems pathway for HLA-E Gene
2 Qiagen pathways for HLA-E Gene
Interacting Proteins for HLA-E Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001916 | positive regulation of T cell mediated cytotoxicity | IDA | 25631937 |
| GO:0002250 | adaptive immune response | IDA | 25631937 |
| GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | TAS,IEA | -- |
| GO:0002476 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib | IDA | 9754572 |
| GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | TAS | -- |
No data available for SIGNOR curated interactions for HLA-E Gene
Drugs & Compounds for HLA-E Gene
Transcripts for HLA-E Gene
mRNA/cDNA for HLA-E Gene
- (4) REFSEQ mRNAs :
- (22) Additional mRNA sequences :
- (1003) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HLA-E Gene
CRISPR Products
- Browse CRISPR knockouts for HLA-E
-
Santa Cruz Biotechnology (SCBT) CRISPR for HLA-E
- GenScript: Design CRISPR guide RNA sequences for HLA-E
miRNA Products
- Search ViGene Biosciences for HLA-E
Inhibitory RNA Products
-
ViGene Biosciences ready-to-package AAV shRNAs for HLA-E gene
Clone Products
- Sino Biological Human cDNA Clone for HLA-E
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for HLA-E Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Thymus (Hematopoietic System)
- T Helper Cells Thymus
- Double Positive Thymocytes Thymus
- T-Cytotoxic Cells Thymus
-
Blood (Cardiovascular System)
- T Helper Cells Thymus
- Double Positive Thymocytes Thymus
- T-Cytotoxic Cells Thymus
-
Spleen (Hematopoietic System)
mRNA differential expression in normal tissues according to GTEx for HLA-E Gene
This gene is overexpressed in Whole Blood (x12.7).
This gene is overexpressed in Skin (26.3) and Peripheral blood mononuclear cells (23.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for HLA-E Gene
SOURCE GeneReport for Unigene cluster for HLA-E Gene:
Hs.650174Evidence on tissue expression from TISSUES for HLA-E Gene
- Blood(4.9)
- Pancreas(4.8)
- Lung(4.7)
- Nervous system(4.7)
- Intestine(4.4)
- Spleen(4.2)
- Skin(3.7)
- Kidney(3.5)
- Stomach(3.3)
- Heart(3)
- Liver(3)
- Lymph node(2.6)
- Muscle(2.5)
- Bone(2.1)
Primer Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HLA-E Gene
Orthologs for HLA-E Gene
This gene was present in the common ancestor of human and mouse.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | PATR-E 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | H2-T23 34 |
|
||
| H2-T-ps 16 |
|
||||
| rat (Rattus norvegicus) |
Mammalia | RT1-S3 34 |
|
- Species where no ortholog for HLA-E was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for HLA-E Gene
(114) SIMAP similar genes for HLA-E Gene using alignment to 14 proteins:
- EA1.2
- EA2.1
- DKFZp686P19218
- HLA-A*0201V3
- HLA-ABC
- HLA-Cw2
- Cw*03
- HLA-Cw3
- HLA G locus
- HLA-B41
- HLA-B*15IL
- FLJ45422
- HLA C*
- HLA-B27
- B-1510
- MHC-G
- HLA-Cw*
- HLA-Bw62.5
- HLA-B15
- HLA-G
- Cw
- HLA-Bw62.4
- HLA-Bw62.3
- HLA-Bw62.1
- HLA-Cw*15P
- MHC
- Cw*08
- B*35
- B*15
- HLAC
- HLA-A26
- HLA-B*4202
- HLA
- HLA-B*4012
- HLA-Cw*03MAC
- HLA-B*3531
- HLA-B52v
- HLA-B1501V2
- HLA-B*15UL
- B*56
- HLA -B
- B-3501
- HLA-C
- HLA-Cw
- HLA-B*1513
- HLA-A*31
- HLA-B*3512
- HLA-A24AK
- HLA-A*0226
- HLA-B18
- HLA-B*40
- HLA-Cw*03
- HLA-Cw*02023
- HLA-B*5501 variant
- HLA-B*15MD
- HLA-All
- HLA-B*1522
- MHC class I HLA-A
- HLA-B*0707
- HLA-B*07ML
- DKFZp686N10220
- HLA-B
- HLA-B35
- HLC-C
- HLA-B*1805
- HLA-A*03
- HLA-Cw*0707
- HLA-Cw*07
- HLA-A*02
- HLA-A*01
- HLA-CW
- HLA-B*13
- HLA-B*18 variant
- HLA-B*
- HLA-A*33
- LOC554223
- HLA-B57
- HLA-B*35JAC
- HLA-B*5603
- HLA-B52
- HLA-G3
- HLA-B*27
- HLA-B*5101 variant
- HLA-DQB1
- HLA-B*35SRE
- HLA-A*24
- HLA-A
- HLA-A null
- HLA B
- HLA-H
- HLA-B*47RG
- HLA-B51
- HLA-A2
- HLA-B*51IM
- HLA-A*0225
- HLA-B gene
- HLA-B*58
- HLA-B*35KM
- HLA-A*2410
- HLA-F
- HLA-J
- HLA-DRB1
- HLA-G2.2
- HLA-B*2712
- HFE
- MR1
- HLA-DMB
- AZGP1
- MICA
- MICB
- HLA-MICA
- FCGRT
- HLA-DQB
- HLQ-DQB1
Variants for HLA-E Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for HLA-E Gene
- HLAE_HUMAN-P13747
- The following alleles of E-1 are known: E*01:01, E*01:02, E*01:03 and E*01:04. The sequence shown is that of E*01:01.
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000413681 | -- | 30,489,388(+) | CCTTC(A/T)TCCTG | upstream-variant-2KB | |
| rs1001937932 | -- | 30,492,442(+) | GTAAG(G/T)GCGGG | intron-variant, reference, missense | |
| rs1002392425 | -- | 30,488,364(+) | CAAGC(A/C)ATTCT | upstream-variant-2KB | |
| rs1003808081 | -- | 30,489,870(+) | GCGGG(C/G)GCCGT | reference, missense | |
| rs1003909041 | -- | 30,490,398(+) | TCTCC(A/G)AGCAA | reference, missense |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2731791 | CNV | deletion | 23290073 |
| esv3411275 | CNV | duplication | 20981092 |
| nsv1074389 | CNV | deletion | 25765185 |
| nsv1122126 | CNV | deletion | 24896259 |
| nsv1144137 | CNV | deletion | 24896259 |
| nsv5242 | CNV | insertion | 18451855 |
| nsv601264 | CNV | loss | 21841781 |
| nsv601481 | CNV | loss | 21841781 |
| nsv970103 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
63.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.79;
33.84% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HLA-E Gene
Disorders for HLA-E Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hematopoietic stem cell transplantation |
|
|
Search HLA-E in MalaCards
View complete list of genes associated with diseases
Relevant External Links for HLA-E
No data available for UniProtKB/Swiss-Prot and Genatlas for HLA-E Gene
Publications for HLA-E Gene
- HLA-E gene polymorphism associated with susceptibility to Kawasaki disease and formation of coronary artery aneurysms. (PMID: 19180512) Lin Y.J. … Tsai F.J. (Arthritis Rheum. 2009) 3 22 46 64
- Ethnic variability in human leukocyte antigen-E haplotypes. (PMID: 19140831) Antoun A. … Briggs D. (Tissue Antigens 2009) 3 22 46 64
- HLA-E*0101 and HLA-G*010101 reduce the risk of Behcet's disease. (PMID: 17257316) Park K.S. … Lee E.S. (Tissue Antigens 2007) 3 22 46 64
- HLA-E*0101 allele in homozygous state favors severe bacterial infections in sickle cell anemia. (PMID: 17961774) Tamouza R. … Charron D. (Hum. Immunol. 2007) 3 22 46 64
- Genetic variants in nonclassical major histocompatibility complex class I human leukocyte antigen (HLA)-E and HLA-G molecules are associated with susceptibility to heterosexual acquisition of HIV-1. (PMID: 16362895) Lajoie J. … Roger M. (J. Infect. Dis. 2006) 3 22 46 64
Products for HLA-E Gene
- Browse R&D Systems for Antibodies
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- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
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- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
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- Custom Antibody ServicesOriGene Antibodies for HLA-E
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HLA-E
- Origene Custom Protein Services for HLA-E
- Browse OriGene Inhibitory RNA Products For HLA-E
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HLA-E
- GenScript: Next-day shipping cDNA ORF clone for HLA-E in any vector
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- GenScript Custom Assay Services for HLA-E
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- GenScript: Design CRISPR guide RNA sequences for HLA-E
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- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
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- Plasmid Preparation
- GenScript Custom Peptide Services for HLA-E
- Sino Biological Human cDNA Clone for HLA-E
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- Sino Biological Cell Lysates
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for HLA-E
- Novus Biologicals proteins and lysates for HLA-E
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for HLA-E
- Abcam proteins for HLA-E
- Search for Assays for HLA-E at Abcam
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- Cloud-Clone Corp. Antibodies for HLA-E
- Cloud-Clone Corp. Proteins for HLA-E
- Cloud-Clone Corp Assay Kits for HLA-E
- antibodies-online Antibodies for HLA-E: See all 107
- antibodies-online Kits for HLA-E: See all 11
- antibodies-online Proteins for HLA-E: See all 6
- Search antibodies-online for peptides
- GeneTex HLA-E antibody for HLA-E
- Search GeneTex for Proteins for HLA-E
- ViGene Biosciences adenoviral particle packaged cDNA for HLA-E gene
- ViGene Biosciences ready-to-package AAV shRNAs for HLA-E gene
- Search ViGene Biosciences for HLA-E
- Santa Cruz Biotechnology (SCBT) Antibodies for HLA-E
- Search Santa Cruz Biotechnology (SCBT) for HLA-E siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HLA-E
- Horizon Cell Lines for HLA-E
- Cyagen custom Knockout/knockin (KOKI) mouse models for HLA-E
- VectorBuilder custom plasmid, inducible vectors for HLA-E
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HLA-E
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HLA-E Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
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