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Aliases for HLA-DRB6 Gene

Aliases for HLA-DRB6 Gene

  • Major Histocompatibility Complex, Class II, DR Beta 6 (Pseudogene) 2 3 5

External Ids for HLA-DRB6 Gene

Previous GeneCards Identifiers for HLA-DRB6 Gene

  • GC06U990052
  • GC06M032291
  • GC06Md32591
  • GC06Md32628
  • GC06M032628
  • GC06M032520

Summaries for HLA-DRB6 Gene

GeneCards Summary for HLA-DRB6 Gene

HLA-DRB6 (Major Histocompatibility Complex, Class II, DR Beta 6 (Pseudogene)) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HLA-DRB6 Gene

Genomics for HLA-DRB6 Gene

Regulatory Elements for HLA-DRB6 Gene

Enhancers for HLA-DRB6 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around HLA-DRB6 on UCSC Golden Path with GeneCards custom track

Genomic Location for HLA-DRB6 Gene

32,552,713 bp from pter
32,560,022 bp from pter
7,310 bases
Minus strand

Genomic View for HLA-DRB6 Gene

Genes around HLA-DRB6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HLA-DRB6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HLA-DRB6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HLA-DRB6 Gene

Proteins for HLA-DRB6 Gene

  • Protein details for HLA-DRB6 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    MHC class II antigen
    Protein Accession:

    Protein attributes for HLA-DRB6 Gene

    34 amino acids
    Molecular mass:
    4086 Da
    Quaternary structure:
    No Data Available

neXtProt entry for HLA-DRB6 Gene

Post-translational modifications for HLA-DRB6 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HLA-DRB6 Gene

Domains & Families for HLA-DRB6 Gene

Gene Families for HLA-DRB6 Gene

Protein Domains for HLA-DRB6 Gene


Suggested Antigen Peptide Sequences for HLA-DRB6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HLA-DRB6: view

No data available for UniProtKB/Swiss-Prot for HLA-DRB6 Gene

Function for HLA-DRB6 Gene

Molecular function for HLA-DRB6 Gene

GENATLAS Biochemistry:
HLA-DR,beta 6 pseudogene,found on DR1,DR2 and DR10 haplotypes

Phenotypes for HLA-DRB6 Gene

genes like me logo Genes that share phenotypes with HLA-DRB6: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HLA-DRB6 Gene

Localization for HLA-DRB6 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HLA-DRB6 Gene

Pathways & Interactions for HLA-DRB6 Gene

SuperPathways for HLA-DRB6 Gene

No Data Available

Interacting Proteins for HLA-DRB6 Gene

Gene Ontology (GO) - Biological Process for HLA-DRB6 Gene


No data available for Pathways by source and SIGNOR curated interactions for HLA-DRB6 Gene

Drugs & Compounds for HLA-DRB6 Gene

No Compound Related Data Available

Transcripts for HLA-DRB6 Gene

mRNA/cDNA for HLA-DRB6 Gene

(6) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HLA-DRB6 Gene

Major histocompatibility complex, class II, DR beta 6 (pseudogene):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HLA-DRB6 Gene

No ASD Table

Relevant External Links for HLA-DRB6 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for HLA-DRB6 Gene

mRNA expression in normal human tissues for HLA-DRB6 Gene

mRNA differential expression in normal tissues according to GTEx for HLA-DRB6 Gene

This gene is overexpressed in Spleen (x5.4).

SOURCE GeneReport for Unigene cluster for HLA-DRB6 Gene:

genes like me logo Genes that share expression patterns with HLA-DRB6: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for HLA-DRB6 Gene

Orthologs for HLA-DRB6 Gene

Evolution for HLA-DRB6 Gene

Gene Tree for HLA-DRB6 (if available)
Gene Tree for HLA-DRB6 (if available)

No data available for Orthologs for HLA-DRB6 Gene

Paralogs for HLA-DRB6 Gene

No data available for Paralogs for HLA-DRB6 Gene

Variants for HLA-DRB6 Gene

Sequence variations from dbSNP and Humsavar for HLA-DRB6 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs66491634 -- 32,560,680(+) AAGCT(G/T)CAGAG upstream-variant-2KB
rs66502252 -- 32,560,744(+) CATGC(C/G)TAAGG upstream-variant-2KB
rs66536077 -- 32,556,220(+) AGGAA(A/G)GCCAT intron-variant
rs66553215 -- 32,556,111(+) CTGCC(C/T)GCCTT intron-variant
rs66570957 -- 32,557,341(+) AAAAA(-/A)TGGCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for HLA-DRB6 Gene

Variant ID Type Subtype PubMed ID
dgv1013n67 CNV loss 20364138
dgv1014n67 CNV loss 20364138
dgv1018n67 CNV loss 20364138
dgv1022n67 CNV loss 20364138
dgv1024n67 CNV loss 20364138
dgv10463n54 CNV loss 21841781
dgv10472n54 CNV loss 21841781
dgv10488n54 CNV loss 21841781
dgv10489n54 CNV loss 21841781
dgv10490n54 CNV loss 21841781
dgv10491n54 CNV gain 21841781
dgv10492n54 CNV gain 21841781
dgv10494n54 CNV gain 21841781
dgv10497n54 CNV loss 21841781
dgv10503n54 CNV loss 21841781
dgv10504n54 CNV gain+loss 21841781
dgv10505n54 CNV gain 21841781
dgv10506n54 CNV loss 21841781
dgv10514n54 CNV loss 21841781
dgv10519n54 CNV gain+loss 21841781
dgv10522n54 CNV loss 21841781
dgv10523n54 CNV loss 21841781
dgv10526n54 CNV loss 21841781
dgv10529n54 CNV loss 21841781
dgv10530n54 CNV loss 21841781
dgv10531n54 CNV loss 21841781
dgv10534n54 CNV gain 21841781
dgv10535n54 CNV loss 21841781
dgv10538n54 CNV gain 21841781
dgv10540n54 CNV gain 21841781
dgv10541n54 CNV gain 21841781
dgv10542n54 CNV gain 21841781
dgv10543n54 CNV gain 21841781
dgv10545n54 CNV loss 21841781
dgv10546n54 CNV gain 21841781
dgv10547n54 CNV loss 21841781
dgv10548n54 CNV loss 21841781
dgv10549n54 CNV loss 21841781
dgv10550n54 CNV loss 21841781
dgv10551n54 CNV loss 21841781
dgv10552n54 CNV gain 21841781
dgv10553n54 CNV loss 21841781
dgv10554n54 CNV gain+loss 21841781
dgv10555n54 CNV loss 21841781
dgv10556n54 CNV loss 21841781
dgv10557n54 CNV loss 21841781
dgv10558n54 CNV loss 21841781
dgv1100e199 CNV deletion 23128226
dgv1105e199 CNV deletion 23128226
dgv1106e199 CNV deletion 23128226
dgv1107e199 CNV deletion 23128226
dgv1108e199 CNV deletion 23128226
dgv121e19 CNV loss 19470904
dgv122e19 CNV loss 19470904
dgv123e19 CNV loss 19470904
dgv384e215 CNV deletion 23714750
dgv5945n100 CNV gain 25217958
dgv5947n100 CNV gain 25217958
dgv5948n100 CNV gain 25217958
dgv5949n100 CNV gain+loss 25217958
dgv5950n100 CNV gain+loss 25217958
dgv6e3 OTHER complex 18987735
dgv998e201 CNV deletion 23290073
esv1007504 CNV gain 20482838
esv21985 CNV gain+loss 19812545
esv2421657 CNV deletion 20811451
esv2422111 CNV deletion 20811451
esv2459937 CNV loss 19546169
esv2671539 CNV deletion 23128226
esv2731847 CNV deletion 23290073
esv2731848 CNV deletion 23290073
esv2759416 CNV gain+loss 17122850
esv2761046 CNV gain+loss 21179565
esv2763944 CNV gain+loss 21179565
esv29958 CNV gain 18421352
esv3272273 CNV deletion 24192839
esv33476 CNV gain+loss 17666407
esv3567555 CNV deletion 23714750
esv3567557 CNV deletion 23714750
esv3567560 CNV deletion 23714750
esv3584531 CNV gain 24956385
esv3584842 CNV loss 24956385
esv3608596 CNV loss 21293372
esv3890831 CNV gain 25118596
esv3890832 CNV gain+loss 25118596
esv3890834 CNV loss 25118596
esv3890835 CNV gain+loss 25118596
esv999877 CNV gain 20482838
nsv1019395 CNV loss 25217958
nsv1020340 CNV loss 25217958
nsv1025310 CNV loss 25217958
nsv1073969 CNV deletion 25765185
nsv1112900 CNV deletion 24896259
nsv1126749 CNV deletion 24896259
nsv1161372 CNV deletion 26073780
nsv428142 CNV gain+loss 18775914
nsv435827 CNV deletion 17901297
nsv442978 CNV loss 18776908
nsv511120 OTHER complex 20534489
nsv515036 CNV gain+loss 21397061
nsv602240 CNV gain 21841781
nsv602463 CNV loss 21841781
nsv602486 CNV gain 21841781
nsv602488 CNV loss 21841781
nsv602490 CNV loss 21841781
nsv602503 CNV gain 21841781
nsv602505 CNV gain 21841781
nsv602507 CNV loss 21841781
nsv602508 CNV loss 21841781
nsv602509 CNV loss 21841781
nsv602511 CNV loss 21841781
nsv602514 CNV loss 21841781
nsv602523 CNV loss 21841781
nsv602531 CNV gain 21841781
nsv602533 CNV loss 21841781
nsv602547 CNV loss 21841781
nsv602561 CNV loss 21841781
nsv7883 CNV gain+loss 18304495
nsv819349 CNV gain 19587683
nsv819451 CNV loss 19587683
nsv823562 CNV gain 20364138
nsv823563 CNV loss 20364138
nsv823566 CNV gain 20364138
nsv830631 CNV gain 17160897

Relevant External Links for HLA-DRB6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HLA-DRB6 Gene

Disorders for HLA-DRB6 Gene

Relevant External Links for HLA-DRB6

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for HLA-DRB6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HLA-DRB6 Gene

Publications for HLA-DRB6 Gene

  1. Complete cDNA sequences of the DRB6 gene from humans and chimpanzees: a possible model of a stop codon readingthrough mechanism in primates. (PMID: 10436177) Moreno-Pelayo M.A. … Arnaiz-Villena A. (Immunogenetics 1999) 2 3 65
  2. Nomenclature for factors of the HLA system, 1991. WHO Nomenclature Committee for factors of the HLA system. (PMID: 1529427) Bodmer J.G. … Sasazuki T. (Tissue Antigens 1992) 2 3 65
  3. A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer. (PMID: 25217961) Al Olama A.A. … Haiman C.A. (Nat. Genet. 2014) 3 65
  4. Antinuclear antibodies and HLA class II alleles in Jamaican patients with systemic lupus erythematosus. (PMID: 17910142) Christian N. … Barton E.N. (West Indian Med J 2007) 3 65
  5. Cytokine gene polymorphisms and acute human liver graft rejection. (PMID: 12089714) WarlAc M.C. … Bouma G.J. (Liver Transpl. 2002) 3 65

Products for HLA-DRB6 Gene

Sources for HLA-DRB6 Gene

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