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Aliases for HLA-DRB6 Gene

Aliases for HLA-DRB6 Gene

  • Major Histocompatibility Complex, Class II, DR Beta 6 (Pseudogene) 2 3

External Ids for HLA-DRB6 Gene

Previous GeneCards Identifiers for HLA-DRB6 Gene

  • GC06U990052
  • GC06M032291
  • GC06Md32591
  • GC06Md32628
  • GC06M032628
  • GC06M032520

Summaries for HLA-DRB6 Gene

GeneCards Summary for HLA-DRB6 Gene

HLA-DRB6 (Major Histocompatibility Complex, Class II, DR Beta 6 (Pseudogene)) is a Pseudogene. Diseases associated with HLA-DRB6 include systemic lupus erythematosus.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HLA-DRB6 Gene

Genomics for HLA-DRB6 Gene

Regulatory Elements for HLA-DRB6 Gene

Genomic Location for HLA-DRB6 Gene

32,552,713 bp from pter
32,560,022 bp from pter
7,310 bases
Minus strand

Genomic View for HLA-DRB6 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for HLA-DRB6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HLA-DRB6 Gene

Proteins for HLA-DRB6 Gene

  • Protein details for HLA-DRB6 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    MHC class II antigen
    Protein Accession:
    Secondary Accessions:

    Protein attributes for HLA-DRB6 Gene

    34 amino acids
    Molecular mass:
    4086 Da
    Quaternary structure:
    No Data Available

neXtProt entry for HLA-DRB6 Gene

Proteomics data for HLA-DRB6 Gene at MOPED

Post-translational modifications for HLA-DRB6 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HLA-DRB6 Gene

Domains for HLA-DRB6 Gene

Gene Families for HLA-DRB6 Gene

  • HLA :Histocompatibility complex

Protein Domains for HLA-DRB6 Gene


Suggested Antigen Peptide Sequences for HLA-DRB6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HLA-DRB6: view

No data available for UniProtKB/Swiss-Prot for HLA-DRB6 Gene

Function for HLA-DRB6 Gene

Molecular function for HLA-DRB6 Gene

GENATLAS Biochemistry:
HLA-DR,beta 6 pseudogene,found on DR1,DR2 and DR10 haplotypes

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for HLA-DRB6 Gene

Localization for HLA-DRB6 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HLA-DRB6 Gene

Pathways for HLA-DRB6 Gene

SuperPathways for HLA-DRB6 Gene

No Data Available

Interacting Proteins for HLA-DRB6 Gene

Gene Ontology (GO) - Biological Process for HLA-DRB6 Gene


No data available for Pathways by source for HLA-DRB6 Gene

Transcripts for HLA-DRB6 Gene

mRNA/cDNA for HLA-DRB6 Gene

(5) Selected AceView cDNA sequences:
(6) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HLA-DRB6 Gene

Major histocompatibility complex, class II, DR beta 6 (pseudogene):
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for HLA-DRB6

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for HLA-DRB6 Gene

No ASD Table

Relevant External Links for HLA-DRB6 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for HLA-DRB6 Gene

mRNA expression in normal human tissues for HLA-DRB6 Gene

mRNA differential expression in normal tissues according to GTEx for HLA-DRB6 Gene

This gene is overexpressed in Spleen (5.4).

SOURCE GeneReport for Unigene cluster for HLA-DRB6 Gene Hs.723344

genes like me logo Genes that share expressions with HLA-DRB6: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for HLA-DRB6 Gene

Orthologs for HLA-DRB6 Gene

Evolution for HLA-DRB6 Gene

Gene Tree for HLA-DRB6 (if available)
Gene Tree for HLA-DRB6 (if available)

No data available for Orthologs for HLA-DRB6 Gene

Paralogs for HLA-DRB6 Gene

No data available for Paralogs for HLA-DRB6 Gene

Variants for HLA-DRB6 Gene

Sequence variations from dbSNP and Humsavar for HLA-DRB6 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs1135085 -- 32,554,700(-) CTCAC(A/G)GTGGA nc-transcript-variant
rs3828849 -- 32,552,887(-) TTCCT(C/T)AGCTC nc-transcript-variant
rs3828851 -- 32,552,844(-) GGCAG(C/T)GCCTC nc-transcript-variant
rs3828853 -- 32,552,804(-) AAATT(G/T)TCCTG nc-transcript-variant
rs9391885 -- 32,557,840(+) ctctc(A/T)cacac intron-variant

Structural Variations from Database of Genomic Variants (DGV) for HLA-DRB6 Gene

Variant ID Type Subtype PubMed ID
dgv1930e1 CNV Complex 17122850
dgv1931e1 CNV Complex 17122850
nsv428142 CNV Gain+Loss 18775914
nsv830631 CNV Gain 17160897
esv21985 CNV Gain+Loss 19812545
esv33476 CNV Gain+Loss 17666407
nsv884743 CNV Loss 21882294
dgv1933e1 CNV Complex 17122850
nsv7883 CNV Gain+Loss 18304495
nsv442978 CNV CNV 18776908
nsv511120 CNV Complex 20534489
nsv884753 CNV Loss 21882294
dgv1045e201 CNV Deletion 23290073
dgv1100e199 CNV Deletion 23128226
dgv6660n71 CNV Gain 21882294
dgv1013n67 CNV Loss 20364138
dgv6668n71 CNV Gain 21882294
esv1007504 CNV Gain 20482838
dgv1014n67 CNV Loss 20364138
esv2459937 CNV Loss 19546169
esv2422111 CNV Deletion 20811451
nsv435827 CNV Deletion 17901297
dgv6e3 CNV Complex 18987735
dgv1018n67 CNV Loss 20364138
esv29958 CNV Gain 18421352
dgv1105e199 CNV Deletion 23128226
dgv105e19 CNV Loss 19470904
dgv6688n71 CNV Gain 21882294
dgv6689n71 CNV Loss 21882294
dgv106e19 CNV Loss 19470904
nsv884963 CNV Gain+Loss 21882294
dgv6691n71 CNV Loss 21882294
dgv6692n71 CNV Loss 21882294
esv2731847 CNV Deletion 23290073
nsv884991 CNV Gain 21882294
esv2671539 CNV Deletion 23128226
dgv6697n71 CNV Gain 21882294
dgv6698n71 CNV Loss 21882294
dgv1022n67 CNV Loss 20364138
dgv6700n71 CNV Loss 21882294
dgv6704n71 CNV Gain 21882294
dgv6707n71 CNV Gain+Loss 21882294
dgv6708n71 CNV Gain 21882294
dgv6709n71 CNV Loss 21882294
dgv6710n71 CNV Gain 21882294
esv2421657 CNV Deletion 20811451
nsv819451 CNV Loss 19587683
dgv6716n71 CNV Gain 21882294
dgv6717n71 CNV Gain 21882294
esv999877 CNV Gain 20482838
dgv6718n71 CNV Gain+Loss 21882294
dgv6719n71 CNV Gain 21882294
essv22046 CNV CNV 17122850
dgv1934e1 CNV Complex 17122850
dgv1935e1 CNV Complex 17122850
dgv6720n71 CNV Loss 21882294
dgv6721n71 CNV Gain+Loss 21882294
dgv6722n71 CNV Loss 21882294
dgv6723n71 CNV Gain+Loss 21882294
dgv6725n71 CNV Gain+Loss 21882294
dgv6726n71 CNV Loss 21882294
dgv6727n71 CNV Loss 21882294
dgv6728n71 CNV Loss 21882294
nsv885197 CNV Gain 21882294
dgv6729n71 CNV Gain 21882294
dgv6730n71 CNV Gain 21882294
dgv6731n71 CNV Loss 21882294
nsv885250 CNV Gain+Loss 21882294
dgv6732n71 CNV Gain 21882294
nsv885258 CNV Gain 21882294
dgv6733n71 CNV Loss 21882294
dgv6734n71 CNV Loss 21882294
dgv1106e199 CNV Deletion 23128226
dgv107e19 CNV Loss 19470904
nsv885275 CNV Gain 21882294
dgv1107e199 CNV Deletion 23128226
nsv885277 CNV Loss 21882294
dgv6735n71 CNV Gain 21882294
dgv6736n71 CNV Loss 21882294
dgv1108e199 CNV Deletion 23128226
esv2731848 CNV Deletion 23290073
dgv6737n71 CNV Gain 21882294
nsv885282 CNV Gain 21882294
dgv6738n71 CNV Gain 21882294
nsv819349 CNV Gain 19587683
dgv6739n71 CNV Loss 21882294
nsv823562 CNV Gain 20364138
nsv823563 CNV Loss 20364138
dgv6740n71 CNV Gain+Loss 21882294
dgv6741n71 CNV Gain 21882294
dgv6742n71 CNV Loss 21882294
dgv6743n71 CNV Gain 21882294
dgv6744n71 CNV Gain+Loss 21882294
dgv6745n71 CNV Gain+Loss 21882294
dgv6746n71 CNV Gain+Loss 21882294
nsv515036 CNV Complex 21397061
dgv6747n71 CNV Loss 21882294
nsv823566 CNV Gain 20364138
dgv1024n67 CNV Loss 20364138
dgv1936e1 CNV Complex 17122850
nsv885349 CNV Loss 21882294
dgv6748n71 CNV Gain 21882294
dgv6749n71 CNV Gain 21882294
dgv6750n71 CNV Gain 21882294
dgv6751n71 CNV Gain+Loss 21882294
dgv6752n71 CNV Gain 21882294

Relevant External Links for HLA-DRB6 Gene

HapMap Linkage Disequilibrium report
Locus Specific Mutation Databases (LSDB)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HLA-DRB6 Gene

Disorders for HLA-DRB6 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for HLA-DRB6 Gene in MalaCards »

(1) Diseases for HLA-DRB6 Gene including...

Relevant External Links for HLA-DRB6

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with HLA-DRB6: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for HLA-DRB6 Gene

Publications for HLA-DRB6 Gene

  1. Complete cDNA sequences of the DRB6 gene from humans and chimpanzees: a possible model of a stop codon readingthrough mechanism in primates. (PMID: 10436177) Moreno-Pelayo M.A. … Arnaiz-Villena A. (Immunogenetics 1999) 2 3
  2. Nomenclature for factors of the HLA system, 1991. WHO Nomenclature Committee for factors of the HLA system. (PMID: 1529427) Bodmer J.G. … Sasazuki T. (Tissue Antigens 1992) 2 3
  3. Primate DRB6 pseudogenes: clue to the evolutionary origin of the HLA-DR2 haplotype. (PMID: 1937579) Figueroa F. … Klein J. (Immunogenetics 1991) 3
  4. Transcription and weak expression of HLA-DRB6: a gene with anomalies in exon 1 and other regions. (PMID: 9601939) Fernandez-Soria V.M. … Arnaiz-Villena A. (Immunogenetics 1998) 3
  5. Cytokine gene polymorphisms and acute human liver graft rejection. (PMID: 12089714) WarlAc M.C. … Bouma G.J. (Liver Transpl. 2002) 3

Products for HLA-DRB6 Gene

Sources for HLA-DRB6 Gene

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