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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HLA-DRB1 Gene

protein-coding   GIFtS: 63
GCID: GC06M032546

major histocompatibility complex, class II, DR beta 1


(Previous symbol: HLA-DR1B)
 Explore 358 diseases affiliated with
HLA-DRB1 via
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Biological research products
for HLA-DRB1    

Aliases
for HLA-DRB1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Major Histocompatibility Complex, Class II, DR Beta 11 2     DR133
HLA-DR1B1 2 5     DR143
DRw102 3     DR163
DW2.2/DR2.22 3     DR43
SS12 5     DR53
DRB12     DR73
HLA-DRB2     DR83
HLA Class II Histocompatibility Antigen, DR-1 Beta Chain2     DR93
Human Leucocyte Antigen DRB12     DRw113
Lymphocyte Antigen DRB12     DRw83
MHC Class II Antigen2     HLA-DRB23
MHC Class II HLA-DR Beta 1 Chain2     Clone P2-Beta-33
MHC Class II HLA-DR-Beta Cell Surface Glycoprotein2     MHC Class II Antigen DRB1*13
MHC Class II HLA-DRw10-Beta2     MHC Class II Antigen DRB1*103
DR-13     MHC Class II Antigen DRB1*113
DR-123     MHC Class II Antigen DRB1*123
DR-133     MHC Class II Antigen DRB1*133
DR-143     MHC Class II Antigen DRB1*143
DR-163     MHC Class II Antigen DRB1*153
DR-43     MHC Class II Antigen DRB1*163
DR-53     MHC Class II Antigen DRB1*33
DR-73     MHC Class II Antigen DRB1*43
DR-83     MHC Class II Antigen DRB1*73
DR-93     MHC Class II Antigen DRB1*83
DR13     MHC Class II Antigen DRB1*93
DR123     

External Ids:    HGNC: 49481   Entrez Gene: 31232   Ensembl: ENSG000001961267   OMIM: 1428575   UniProtKB: P042293   
UniProtKB: P019123   UniProtKB: P137603   UniProtKB: P137613   UniProtKB: Q301343   UniProtKB: Q9TQE03   
UniProtKB: Q301673   UniProtKB: P200393   UniProtKB: Q95IE33   UniProtKB: Q5Y7A73   UniProtKB: Q9GIY33   
UniProtKB: P019113   UniProtKB: Q299743   

Export aliases for HLA-DRB1 gene to outside databases

Previous GC identifers: GC06U990049 GC06Md32547 GC06M032317 GC06Md32654 GC06M032656


Summaries
for HLA-DRB1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for HLA-DRB1:
HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha
(DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by
presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells
(APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6
exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the
transmembrane domain; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the
polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing
for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level
five times higher than its paralogs DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1
are linked with either none or one of the genes DRB3, DRB4 and DRB5. There are 4 related pseudogenes: DRB2, DRB6,
DRB7, DRB8 and DRB9. (provided by RefSeq, Jul 2008)

UniProtKB/ace: 2B11_HUMAN, P04229 (see all)
Function: Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and
presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides
of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins
that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous
antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and
for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their
way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal
compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a
source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition
to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molecules and CD74
and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molecule that presents an
antigen, three MHC class II molecules (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the
ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen
processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a
small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM
via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molecules
until primary high affinity antigenic peptides are bound. The MHC II molecule bound to a peptide is then transported
to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by
HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal miroenvironment has been implicated in the
regulation of antigen loading into MHC II molecules, increased acidification produces increased proteolysis and
efficient peptide loading

Gene Wiki entry for HLA-DRB1


Genomic Views
for HLA-DRB1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NT_113891.2  NT_167248.1  NC_000006.11  NC_018917.1  NT_007592.15  NT_167249.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HLA-DRB1 gene promoter:
         HOXA3   AML1a   p53   CUTL1   CBF-C   YY1   CBF-B   CBF-A   CP1A   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: HLA-DRB1 promoter sequence
   Search SABiosciences Chromatin IP Primers for HLA-DRB1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HLA-DRB1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p21.32   HGNC cytogenetic band: 6p21.3

HLA-DRB1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HLA-DRB1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M032546:  view genomic region     (about GC identifiers)

Start:
 32,546,546 bp from pter      End:
 32,557,625 bp from pter
Size:
 11,080 bases      Orientation:
 minus strand

2 alternative locations:
Chr6-,ALT_REF_LOCI_2 32,475,947-32,528,486      Chr6-,ALT_REF_LOCI_7 32,510,207-32,722,298     

Proteins
for HLA-DRB1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: 2B11_HUMAN, P04229 (See protein sequence)
Recommended Name: HLA class II histocompatibility antigen, DRB1-1 beta chain precursor  
Size: 266 amino acids; 29914 Da
Subunit: Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic
reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant
chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes
sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC
class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of
antigenic peptides
Subcellular location: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass
type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome
membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome
membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of
intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation
6/39 PDB 3D structures from and Proteopedia for HLA-DRB1 (see all 39):
1AQD (3D)        1DLH (3D)        1FYT (3D)        1HXY (3D)        1JWM (3D)        1JWS (3D)    
Secondary accessions: A4F5N0 A8K098 O62869 P13758 Q06662 Q30116 Q30117 Q5Y7E9 Q7M2H4 Q95461 Q9BCL7
Q9GIK5 Q9MXZ0 Q9MXZ5 Q9TQ91

UniProtKB/Swiss-Prot: 2B13_HUMAN, P01912 (See protein sequence)

Recommended Name: HLA class II histocompatibility antigen, DRB1-3 chain precursor  
Size: 266 amino acids; 30120 Da
Subunit: Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic
reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant
chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes
sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC
class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of
antigenic peptides
Subcellular location: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass
type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome
membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome
membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of
intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation
1 PDB 3D structure from and Proteopedia for HLA-DRB1:
1A6A (3D)    

UniProtKB/Swiss-Prot: 2B14_HUMAN, P13760 (See protein sequence)

Recommended Name: HLA class II histocompatibility antigen, DRB1-4 beta chain precursor  
Size: 266 amino acids; 30112 Da
Subunit: Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic
reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant
chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes
sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC
class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of
antigenic peptides
Subcellular location: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass
type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome
membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome
membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of
intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation
6/8 PDB 3D structures from and Proteopedia for HLA-DRB1 (see all 8):
1D5M (3D)        1D5X (3D)        1D5Z (3D)        1D6E (3D)        1J8H (3D)        2SEB (3D)    
Secondary accessions: O19717 O19739 P13759 Q29875 Q30145 Q9GIX9 Q9GIY4 Q9MY13 Q9XRY5

UniProtKB/Swiss-Prot: 2B17_HUMAN, P13761 (See protein sequence)

Recommended Name: HLA class II histocompatibility antigen, DRB1-7 beta chain precursor  
Size: 266 amino acids; 29822 Da
Subunit: Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic
reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant
chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes
sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC
class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of
antigenic peptides
Subcellular location: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass
type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome
membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome
membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of
intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation
Secondary accessions: B0UYW1 O46699 O46872

UniProtKB/Swiss-Prot: 2B18_HUMAN, Q30134 (See protein sequence)

Recommended Name: HLA class II histocompatibility antigen, DRB1-8 beta chain precursor  
Size: 266 amino acids; 30004 Da
Subunit: Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic
reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant
chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes
sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC
class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of
antigenic peptides
Subcellular location: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass
type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome
membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome
membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of
intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation
Secondary accessions: O19718 O19788 Q29968 Q30108 Q30115 Q9BCP0 Q9BCP1 Q9BCP2 Q9BD33 Q9TQ37 Q9UIM9

UniProtKB/Swiss-Prot: 2B19_HUMAN, Q9TQE0 (See protein sequence)

Recommended Name: HLA class II histocompatibility antigen, DRB1-9 beta chain precursor  
Size: 266 amino acids; 29826 Da
Subunit: Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic
reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant
chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes
sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC
class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of
antigenic peptides
Subcellular location: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass
type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome
membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome
membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of
intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation
Secondary accessions: Q30149

UniProtKB/Swiss-Prot: 2B1A_HUMAN, Q30167 (See protein sequence)

Recommended Name: HLA class II histocompatibility antigen, DRB1-10 beta chain precursor  
Size: 266 amino acids; 30002 Da
Subunit: Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic
reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant
chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes
sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC
class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of
antigenic peptides
Subcellular location: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass
type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome
membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome
membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of
intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation
Secondary accessions: P01914 Q9MYF5

UniProtKB/Swiss-Prot: 2B1B_HUMAN, P20039 (See protein sequence)

Recommended Name: HLA class II histocompatibility antigen, DRB1-11 beta chain precursor  
Size: 266 amino acids; 30160 Da
Subunit: Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic
reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant
chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes
sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC
class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of
antigenic peptides
Subcellular location: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass
type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome
membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome
membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of
intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation
Secondary accessions: Q30006 Q9GIX8

UniProtKB/Swiss-Prot: 2B1C_HUMAN, Q95IE3 (See protein sequence)

Recommended Name: HLA class II histocompatibility antigen, DRB1-12 beta chain precursor  
Size: 266 amino acids; 29878 Da
Subunit: Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic
reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant
chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes
sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC
class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of
antigenic peptides
Subcellular location: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass
type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome
membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome
membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of
intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation
Secondary accessions: A7LA26 B0LUZ6 B6VCX2 B7UDB2 O19585 Q19AF2 Q29771 Q2L9H4 Q2MZ92 Q5EER6 Q5NDB9
Q5UT58 Q5Y7G0 Q768U4 Q7YP04 Q861H8 Q95IT6 Q9BD40

UniProtKB/Swiss-Prot: 2B1D_HUMAN, Q5Y7A7 (See protein sequence)

Recommended Name: HLA class II histocompatibility antigen, DRB1-13 beta chain precursor  
Size: 266 amino acids; 30008 Da
Subunit: Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic
reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant
chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes
sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC
class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of
antigenic peptides
Subcellular location: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass
type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome
membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome
membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of
intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation
Sequence caution: Sequence=CAB40418.1; Type=Erroneous gene model prediction;
Secondary accessions: A0MWF2 A2ICT1 A4ZXA5 A4ZXA6 A7UHG2 A7X5K7 A8YQE9 B0BK85 B3VTQ3 B5A8Y2 B5A8Y3
B5B9V6 B5QSK8 C0LAB5 O02930 O62889 O78047 P79545 Q14280 Q14QT2 Q19K86 Q1G0Z9 Q1KLJ6 Q29673 Q29720
Q29722 Q29806 Q29833 Q29874 Q29886 Q2MF40 Q2YHQ2 Q30112 Q3LA93 Q3LA94 Q3LA95 Q3LA96 Q3LA97 Q3LA98
Q3LA99 Q3LAA0 Q3LAA1 Q3LAA2 Q3MQ60 Q53IG1 Q56FP2 Q56FP3 Q58F52 Q5K3W2 Q5UBA2 Q5W3L4 Q6REE2 Q6U387
Q701T1 Q70Q85 Q768U2 Q7YP03 Q7YQ26 Q7YQA3 Q860E5 Q860H8 Q860Z3 Q861G6 Q861H0 Q861H4 Q8HWQ6 Q8WMA0
Q95389 Q95HL1 Q96HZ9 Q9BCP5 Q9BD21 Q9GIP3 Q9GJ25 Q9GJ60 Q9GJF8 Q9GJF9 Q9GJG0 Q9MY45 Q9MY56 Q9TPW3
Q9TPW9 Q9TPX4 Q9UBY1 Q9UIN0 Q9XRX1 Q9Y453

UniProtKB/Swiss-Prot: 2B1E_HUMAN, Q9GIY3 (See protein sequence)

Recommended Name: HLA class II histocompatibility antigen, DRB1-14 beta chain precursor  
Size: 266 amino acids; 30139 Da
Subunit: Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic
reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant
chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes
sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC
class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of
antigenic peptides
Subcellular location: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass
type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome
membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome
membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of
intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation
Sequence caution: Sequence=CAB45249.1; Type=Erroneous gene model prediction;
Secondary accessions: A0N0W1 A2TGX3 A4ZY86 A5H000 A5HKN8 A7DZP9 A7X5B1 A7X5B7 A7X5E0 A7X5E6 A7X5H8
A9JPG0 B1GWE7 B2CR03 B2LVF9 B2NJ29 B2ZCY1 B3VTP8 B5B8U0 B5B9V5 B5LZ25 B6VEL9 B9VRA4 B9X248 O02876
O46793 O77969 O78210 Q0PQ39 Q155F7 Q1AP33 Q1JRP3 Q27PR6 Q27PR7 Q29734 Q29770 Q29772 Q29800 Q2A120
Q2HZE5 Q2LE76 Q2MJA6 Q2VQU1 Q307W5 Q31636 Q3LA87 Q3LA88 Q3LA89 Q3LA90 Q3LA91 Q3LA92 Q3T919 Q4PRC3
Q4PRC5 Q4VZY7 Q56FP1 Q5BM92 Q5U9W6 Q683P7 Q70GL2 Q7YNY9 Q7YQA5 Q860D8 Q860D9 Q860S0 Q861H5 Q861H7
Q8MH59 Q8MH60 Q8WLU3 Q95348 Q95HK1 Q95HL0 Q95IG2 Q9GIL5 Q9GIL6 Q9GIY0 Q9GIY1 Q9GIY2 Q9GJ56 Q9GJ57
Q9GJ58 Q9TPB6 Q9TPW1 Q9XRY4 Q9Y4H7

UniProtKB/Swiss-Prot: 2B1F_HUMAN, P01911 (See protein sequence)

Recommended Name: HLA class II histocompatibility antigen, DRB1-15 beta chain precursor  
Size: 266 amino acids; 29966 Da
Subunit: Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic
reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant
chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes
sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC
class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of
antigenic peptides
Subcellular location: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass
type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome
membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome
membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of
intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation
Miscellaneous: The chain shown constituted about 70% of a pool of at least seven similar beta chains
3 PDB 3D structures from and Proteopedia for HLA-DRB1:
1BX2 (3D)        1YMM (3D)        2WBJ (3D)    
Secondary accessions: Q29790 Q29975 Q30142 Q30166 Q32MY7 Q56FN9 Q5Y7B0 Q5Y7B9

UniProtKB/Swiss-Prot: 2B1G_HUMAN, Q29974 (See protein sequence)

Recommended Name: HLA class II histocompatibility antigen, DRB1-16 beta chain precursor  
Size: 266 amino acids; 30030 Da
Subunit: Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic
reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant
chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes
sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC
class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of
antigenic peptides
Subcellular location: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass
type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome
membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome
membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of
intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation
Secondary accessions: A7X5J4 O98212 Q0PGR5 Q29792 Q30120 Q30159 Q30200 Q3HUP9 Q3KTM1 Q3LA84 Q6T865
Q95383

Explore the universe of human proteins at neXtProt for HLA-DRB1: NX_Q29974

Post-translational modifications:

  • Ubiquitinated by MARCH1 and MARCH8 at Lys-254 leading to sorting into the endosome system and down-regulation of MHC
    • class II (Probable)1
  • View modification sites using PhosphoSitePlus2 (HLA-DRB4)
  • View neXtProt modification sites for NX_Q29974

    • HLA-DRB1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001230894.1  NP_002115.2  

    ENSEMBL proteins: 
     ENSP00000353099  
    Reactome Protein details: Q30167 Q5Y7A7 P04229 Q9TQE0 Q9GIY3 P01911 Q29974 P20039 Q95IE3 P01912 P13760 Q30134 P13761
    Human Recombinant Protein Products: 
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: HLA-DRB1
    OriGene Protein Over-expression Lysate: HLA-DRB1
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    Novus Biologicals HLA-DRB1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for HLA-DRB1

    Gene Ontology (GO): 5/17 cellular component terms (GO ID links to tree view) (see all 17):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0005765lysosomal membrane TAS--
    GO:0005789endoplasmic reticulum membrane ----
    GO:0005794Golgi apparatus ----
    GO:0005886plasma membrane TAS--


    HLA-DRB1 for ontologies           About GeneDecksing



    HLA-DRB1 Antibody Products: 
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    Uscn ELISAs and CLIAs for HLA-DRB1

    Protein Domains /
    Families
    for HLA-DRB1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HLA-DRB1 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR011162 MHC_I/II-like_Ag-recog
     IPR000353 MHC_II_b_N
     IPR013783 Ig-like_fold
     IPR014745 MHC_II_a/b_N
     IPR003597 Ig_C1-set

    Graphical View of Domain Structure for InterPro Entry P04229
    Graphical View of Domain Structure for InterPro Entry P01912
    Graphical View of Domain Structure for InterPro Entry P13760
    Graphical View of Domain Structure for InterPro Entry P13761
    Graphical View of Domain Structure for InterPro Entry Q30134
    Graphical View of Domain Structure for InterPro Entry Q9TQE0
    Graphical View of Domain Structure for InterPro Entry Q30167
    Graphical View of Domain Structure for InterPro Entry P20039
    Graphical View of Domain Structure for InterPro Entry Q95IE3
    Graphical View of Domain Structure for InterPro Entry Q5Y7A7
    Graphical View of Domain Structure for InterPro Entry Q9GIY3
    Graphical View of Domain Structure for InterPro Entry P01911
    Graphical View of Domain Structure for InterPro Entry Q29974

    ProtoNet protein and cluster: P04229

    2 Blocks protein families:
    IPB000353 Class II histocompatibility antigen
    IPB003597 Immunoglobulin C-type


    UniProtKB/Swiss-Prot: 2B11_HUMAN, P04229
    Similarity: Belongs to the MHC class II family
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain

    UniProtKB/Swiss-Prot: 2B13_HUMAN, P01912
    Similarity: Belongs to the MHC class II family
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain

    UniProtKB/Swiss-Prot: 2B14_HUMAN, P13760
    Similarity: Belongs to the MHC class II family
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain

    UniProtKB/Swiss-Prot: 2B17_HUMAN, P13761
    Similarity: Belongs to the MHC class II family
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain

    UniProtKB/Swiss-Prot: 2B18_HUMAN, Q30134
    Similarity: Belongs to the MHC class II family
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain

    UniProtKB/Swiss-Prot: 2B19_HUMAN, Q9TQE0
    Similarity: Belongs to the MHC class II family
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain

    UniProtKB/Swiss-Prot: 2B1A_HUMAN, Q30167
    Similarity: Belongs to the MHC class II family
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain

    UniProtKB/Swiss-Prot: 2B1B_HUMAN, P20039
    Similarity: Belongs to the MHC class II family
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain

    UniProtKB/Swiss-Prot: 2B1C_HUMAN, Q95IE3
    Similarity: Belongs to the MHC class II family
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain

    UniProtKB/Swiss-Prot: 2B1D_HUMAN, Q5Y7A7
    Similarity: Belongs to the MHC class II family
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain

    UniProtKB/Swiss-Prot: 2B1E_HUMAN, Q9GIY3
    Similarity: Belongs to the MHC class II family
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain

    UniProtKB/Swiss-Prot: 2B1F_HUMAN, P01911
    Similarity: Belongs to the MHC class II family
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain

    UniProtKB/Swiss-Prot: 2B1G_HUMAN, Q29974
    Similarity: Belongs to the MHC class II family
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain


    Function
    for HLA-DRB1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:
    UniProtKB/ace: 2B11_HUMAN, P04229 (see all)
    Function: Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and
    presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides
    of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins
    that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous
    antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and
    for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their
    way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal
    compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a
    source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition
    to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molecules and CD74
    and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molecule that presents an
    antigen, three MHC class II molecules (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the
    ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen
    processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a
    small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM
    via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molecules
    until primary high affinity antigenic peptides are bound. The MHC II molecule bound to a peptide is then transported
    to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by
    HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal miroenvironment has been implicated in the
    regulation of antigen loading into MHC II molecules, increased acidification produces increased proteolysis and
    efficient peptide loading

         Genatlas biochemistry entry for HLA-DRB1:
    HLA-DR,beta 1 chain,determining DR1,3,4,5 etc

    miRNA
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    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032395MHC class II receptor activity TAS3456344
    GO:0042605peptide antigen binding ISS--


    HLA-DRB1 for ontologies           About GeneDecksing



    Pathways & Interactions
    for HLA-DRB1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/34 super-pathways (see all 34) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Transport of MHC II:Ii complex along Golgi to TGN
    		Transport of MHC II:Ii complex to plasma membrane1.00
    		Trafficking of nonameric complex in the endocytic pathway1.00
    		Transport of MHC II:Ii complex along Golgi to TGN1.00
    		Internalization of MHC II:Ii clathrin coated vesicle0.52
    		Insertion of MHC II:Ii complex in to the plasma membrane1.00
    2Translocation of ZAP-70 to Immunological synapse
    		Translocation of ZAP-70 to Immunological synapse1.00
    		PD-1 signaling0.76
    		Phosphorylation of CD3 and TCR zeta chains0.85
    		Generation of second messenger molecules0.64
    3Cytokine Signaling in Immune system
    		Cytokine Signaling in Immune system1.00
    		Interferon Signaling0.61
    4Immune System
    		Immune System1.00
    		Adaptive Immune System0.59
    5Interferon gamma signaling
    		Interferon gamma signaling1.00
    		Expression of IFNG-stimulated genes0.72

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    5/6 EMD Millipore Pathways for HLA-DRB1 (see all 6)
        Immune response Antigen presentation by MHC class II
    G-protein signaling N-RAS regulation pathway
    Immune response IL-22 signaling pathway
    Immune response NFAT in immune response
    Immune response ICOS pathway in T-helper cell

    5/12 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for HLA-DRB1 (see all 12)
        THC Differentiation Pathway
    Calcium Mediated T-Cell Apoptosis
    IL-4 Pathway
    ICos-ICosL Pathway in T-Helper Cell
    CDC42 Pathway

    5/6 GeneGo (Thomson Reuters) Pathways for HLA-DRB1 (see all 6)
        Immune response Antigen presentation by MHC class II
    Immune response ICOS pathway in T-helper cell
    Immune response T cell receptor signaling pathway
    Immune response IL-22 signaling pathway
    G-protein signaling N-RAS regulation pathway

    5 BioSystems Pathways for HLA-DRB1 
        Cytokines and Inflammatory Response
    IL12 signaling mediated by STAT4
    IL12-mediated signaling events
    CXCR4-mediated signaling events
    TCR signaling in naive CD4+ T cells

    5/20        Reactome Pathways for HLA-DRB1 (see all 20)
        Internalization of MHC II:Ii clathrin coated vesicle
    Costimulation by the CD28 family
    Transport of MHC II:Ii complex along Golgi to TGN
    Transport of MHC II:Ii complex to plasma membrane
    Transport of antigen loaded MHC II molecules to surface


    5/18         Kegg Pathways  (Kegg details for HLA-DRB1) (see all 18):
        Phagosome
    Cell adhesion molecules (CAMs)
    Antigen processing and presentation
    Hematopoietic cell lineage
    Intestinal immune network for IgA production


    HLA-DRB1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HLA-DRB1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/198 Interacting proteins for HLA-DRB1 (P019122 P042292 ENSP000003530994 Q299742, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 198)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000235657P018922, ENSP000003885264MINT-8407259 MINT-8407185 STRING: ENSP00000388526
    HLA-DRAP019032, ENSP000003787864MINT-24881 STRING: ENSP00000378786
    ANXA6P081332MINT-8407259 MINT-8407185
    CD81P600332MINT-8407259 MINT-8407185
    CD9P219262MINT-8407259 MINT-8407185
    About this table

    Gene Ontology (GO): 5/18 biological process terms (GO ID links to tree view) (see all 18):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002381immunoglobulin production involved in immunoglobulin mediated immune response ISS--
    GO:0002437inflammatory response to antigenic stimulus ISS--
    GO:0002455humoral immune response mediated by circulating immunoglobulin ISS--
    GO:0002504antigen processing and presentation of peptide or polysaccharide antigen via MHC class II ----
    GO:0006955immune response NAS--


    HLA-DRB1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for HLA-DRB1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    HLA-DRB1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HLA-DRB1

    1 DrugBank Compound for HLA-DRB1    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Glatiramer AcetateCOP-1 (see all 3)147245-92-9targetbinder15371592 11752352

    10/17 Novoseek chemical compound relationships for HLA-DRB1 gene (see all 17)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    dr-10 77.3 6 7780115 (1), 9550403 (1), 8754259 (1), 10626740 (1)
    dr-16 73.6 1 9243764 (1)
    dpa 1 73.1 5 8782076 (1), 8863870 (1), 17060025 (1), 10616003 (1) (see all 5)
    oligonucleotide 53.4 22 8117375 (1), 12823773 (1), 15865503 (1), 18718089 (1) (see all 20)
    gold sodium thiomalate 36 2 11093435 (1)
    valine 30.5 4 9098452 (1), 8500529 (1), 10439317 (1), 2369430 (1)
    amino acid 19.7 1 1533151 (1)
    c-peptide 4.17 1 15388265 (1)
    atp 3.36 2 12658812 (2)
    lysine 0 2 7738179 (1), 7612412 (1)

    Search CenterWatch for drugs/clinical trials and news about HLA-DRB1 / 2B1G 

    Transcripts
    for HLA-DRB1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for HLA-DRB1 gene (2 alternative transcripts): 
    NM_001243965.1  NM_002124.3  

    Unigene Clusters for HLA-DRB1:

    Major histocompatibility complex, class II, DR beta 1
    Hs.534322  [show with all ESTs], Hs.696211  [show with all ESTs], Hs.736560  [show with all ESTs]
    Unigene Representative Sequences: AK290388, AK225690, BG484513
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000360004(uc021yvx.1 uc003obp.4 uc011dqb.1 uc011dqc.1)


    miRNA
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    Inhib. RNA
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    Clone
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    GenScript: all cDNA clones in your preferred vector: HLA-DRB1 (NM_002124)
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    Primer
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    Additional cDNA sequence: 

    AF004817.1 AJ580838.1 D86415.1 M15070.1 M17386.1 M25266.1 M27014.1 M59798.1 

    24/70 DOTS entries (see all 70):

    DT.92410344  DT.92028787  DT.91706875  DT.95164729  DT.92047682  DT.100776434  DT.95164752  DT.92382901 
    DT.95164731  DT.121314547  DT.87079048  DT.40115364  DT.100781798  DT.100778733  DT.100650571  DT.100766538 
    DT.121314746  DT.92380890  DT.121314807  DT.95230813  DT.97857272  DT.95164743  DT.91802323  DT.92467723 

    24/89 AceView cDNA sequences (see all 89):

    M16731 X02902 BV207240 M17381 BV183568 BV201637 L42143 AH002891 
    AJ245881 AF291675 AJ297586 BV207185 M15073 AJ536121 BC024269 BV207249 
    BV207188 U84892 BV207191 X12544 BV200472 BV207037 BV200469 BV207182 

    GeneLoc Exon Structure


    Expression
    for HLA-DRB1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HLA-DRB1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACAGCGCTGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See HLA-DRB1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HLA-DRB1

    SOURCE GeneReport for Unigene clusters: Hs.534322 Hs.696211 Hs.736560
        SABiosciences Expression via Pathway-Focused PCR Arrays including HLA-DRB1: 
              Multiple Sclerosis in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat

    Primer
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    In Situ
    Assay Products:     
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    Orthologs
    for HLA-DRB1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for HLA-DRB1 gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves --
    E2JF30_CHICK6
    (see all 3)    		 MHC class II beta chain
    (see all 3)    		 54(a)
    52(a)
    (see all 3)    		 many ↔ many
    many ↔ many
    (see all 3)    		 16(375632-376577)
    16(69833-71353)
    lizard
    (Anolis carolinensis)    		 Reptilia HLA-DPB16
    		 --
    		 45(a)
    		 1 → many
    		 GL343520.1(320149-320904)
    African clawed frog
    (Xenopus laevis)    		 Amphibia D13688.12   -- 78.3(n)    D13688.1 


    ENSEMBL Gene Tree for HLA-DRB1 (if available)
    TreeFam Gene Tree for HLA-DRB1 (if available) 

    Paralogs
    for HLA-DRB1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HLA-DRB1 gene
    HLA-DRB52  HLA-DQA12  HLA-DPA12  HLA-DQB12  HLA-DRA2  HLA-DOB2  HLA-DMA2  HLA-DQB22  
    ENSG000002489932  HLA-DOA2  HLA-DMB2  HLA-DQA22  HLA-DPB12  
    18/233 SIMAP similar genes for HLA-DRB1 using alignment to 1823 protein entries:     2B11_HUMAN (see all proteins) (see all similar genes):
    HLA DRB4    HLA-DRB1*0402    HLA-DRB1*0407    HLA-DRB1*1301    HLA-DRB1*1302    HLA-DRB1*1402
    HLA-All    HLA-A null    HLA-A*03    HLA-DRB13    HLA-DRB1*1605    HLA-B27
    HLA-DRB1*1327    HLA-Cw3    HLA-DRB14    HLA-D8.2V    HLA DRB1    HLA-DRB4$0101

    HLA-DRB1 for paralogs           About GeneDecksing



    Genomic Variants
    for HLA-DRB1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    UniProtKB/Swiss-Prot: 2B1G_HUMAN, Q29974
    Polymorphism: The following alleles of DRB1-1 are known: DRB1*01:01; DRB1*01:02; DRB1*01:03; DRB1*01:04; DRB1*01:05;
    DRB1*01:06; DRB1*01:07; DRB1*01:08; DRB1*01:09; DRB1*01:10; DRB1*01:11; DRB1*01:12; DRB1*01:13; DRB1*01:14;
    DRB1*01:15; DRB1*01:16; DRB1*01:17; DRB1*01:18; DRB1*01:19; DRB1*01:20 and DRB1*01:21. The sequence shown is that of
    DRB1*01:01
    Polymorphism: The following alleles of DRB1-3 are known: DRB1*03:01; DRB1*03:02; DRB1*03:03; DRB1*03:04; DRB1*03:05;
    DRB1*03:06; DRB1*03:07; DRB1*03:08; DRB1*03:09; DRB1*03:10; DRB1*03:11; DRB1*03:12; DRB1*03:13; DRB1*03:14;
    DRB1*03:15; DRB1*03:16; DRB1*03:17; DRB1*03:18; DRB1*03:19; DRB1*03:20; DRB1*03:21; DRB1*03:22; DRB1*03:23;
    DRB1*03:24; DRB1*03:25; DRB1*03:26; DRB1*03:27; DRB1*03:28; DRB1*03:29; DRB1*03:30; DRB1*03:31; DRB1*03:32;
    DRB1*03:33; DRB1*03:34; DRB1*03:35; DRB1*03:36; DRB1*03:37; DRB1*03:38; DRB1*03:39; DRB1*03:40 and DRB1*03:41. The
    sequence shown is that of DRB1*03:01
    Polymorphism: The following alleles of DRB1-4 are known: DRB1*04:01, DRB1*04:02, DRB1*04:03, DRB1*04:04, DRB1*04:05,
    DRB1*04:06, DRB1*04:07, DRB1*04:08, DRB1*04:09, DRB1*04:10, DRB1*04:11, DRB1*04:12, DRB1*04:13, DRB1*04:14,
    DRB1*04:15, DRB1*04:16, DRB1*04:17, DRB1*04:18, DRB1*04:19, DRB1*04:20, DRB1*04:21, DRB1*04:22, DRB1*04:23,
    DRB1*04:24, DRB1*04:25, DRB1*04:26, DRB1*04:27, DRB1*04:28, DRB1*04:29, DRB1*04:30, DRB1*04:31, DRB1*04:32,
    DRB1*04:33, DRB1*04:34, DRB1*04:35, DRB1*04:36, DRB1*04:37, DRB1*04:38, DRB1*04:39, DRB1*04:40, DRB1*04:41,
    DRB1*04:42, DRB1*04:43, DRB1*04:44, DRB1*04:45, DRB1*04:46, DRB1*04:47, DRB1*04:48, DRB1*04:49, DRB1*04:50,
    DRB1*04:51, DRB1*04:52, DRB1*04:53, DRB1*04:54, DRB1*04:55, DRB1*04:56, DRB1*04:57, DRB1*04:58, DRB1*04:59,
    DRB1*04:60, DRB1*04:61, DRB1*04:62, DRB1*04:63, DRB1*04:64, DRB1*04:65, DRB1*04:66, DRB1*04:67, DRB1*04:68,
    DRB1*04:69, DRB1*04:70, DRB1*04:71, DRB1*04:72, DRB1*04:73, DRB1*04:74, DRB1*04:75, DRB1*04:76, DRB1*04:77 and
    DRB1*04:78. The sequence shown is that of DRB1*04:01
    Polymorphism: The following alleles of DRB1-7 are known: DRB1*07:01, DRB1*07:03, DRB1*07:04, DRB1*07:05, DRB1*07:06,
    DRB1*07:07, DRB1*07:08, DRB1*07:09, DRB1*07:11, DRB1*07:12, DRB1*07:13, DRB1*07:14, DRB1*07:15, DRB1*07:16 and
    DRB1*07:17. The sequence shown is that of DRB1*07:01
    Polymorphism: Allele DRB1*07:01 is associated with persistent hepatitis C virus (HCV) infections [MIM:609532]
    Polymorphism: The following alleles of DRB1-8 are known: DRB1*08:01 (Dw8.1), DRB1*08:02 (Dw8.2; DRB1L), DRB1*08:03
    (Dw8.3); DRB1*08:04; DRB1*08:05, DRB1*08:06, DRB1*08:07, DRB1*08:08, DRB1*08:09, DRB1*08:10, DRB1*08:11, DRB1*08:12,
    DRB1*08:13, DRB1*08:14, DRB1*08:15, DRB1*08:16, DRB1*08:17, DRB1*08:18, DRB1*08:19, DRB1*08:20, DRB1*08:21,
    DRB1*08:22, DRB1*08:23, DRB1*08:24, DRB1*08:25, DRB1*08:26, DRB1*08:27, DRB1*08:28, DRB1*08:29, DRB1*08:30,
    DRB1*08:31, DRB1*08:32, DRB1*08:33, DRB1*08:34, DRB1*08:35 and DRB1*08:36. The sequence shown is that of DRB1*08:01
    Polymorphism: The following alleles of DRB1-9 are known: DRB1*09:01, DRB1*09:02, DRB1*09:03, DRB1*09:04, DRB1*09:05,
    DRB1*09:06, DRB1*09:07 and DRB1*09:08. The sequence shown is that of DRB1*09:01
    Polymorphism: The following alleles of DRB1-10 are known: DRB1*10:01; DRB1*10:02 and DRB1*10:03. The sequence shown is
    that of DRB1*10:01
    Polymorphism: The following alleles of DRB1-11 are known: DRB1*11:01, DRB1*11:03, DRB1*11:04, DRB1*11:05, DRB1*11:06,
    DRB1*11:07, DRB1*11:08, DRB1*11:09, DRB1*11:10, DRB1*11:11, DRB1*11:12, DRB1*11:13, DRB1*11:14, DRB1*11:15,
    DRB1*11:16, DRB1*11:17, DRB1*11:18, DRB1*11:19, DRB1*11:20, DRB1*11:21, DRB1*11:22, DRB1*11:23, DRB1*11:24,
    DRB1*11:25, DRB1*11:26, DRB1*11:27, DRB1*11:28, DRB1*11:29, DRB1*11:30, DRB1*11:31, DRB1*11:32, DRB1*11:33,
    DRB1*11:34, DRB1*11:35, DRB1*11:36, DRB1*11:37, DRB1*11:38, DRB1*11:39, DRB1*11:40, DRB1*11:41, DRB1*11:42,
    DRB1*11:43, DRB1*11:44, DRB1*11:45, DRB1*11:46, DRB1*11:47, DRB1*11:48, DRB1*11:49, DRB1*11:50, DRB1*11:51,
    DRB1*11:52, DRB1*11:53, DRB1*11:54, DRB1*11:55, DRB1*11:56, DRB1*11:57, DRB1*11:58, DRB1*11:59, DRB1*11:60,
    DRB1*11:61, DRB1*11:62, DRB1*11:63, DRB1*11:64, DRB1*11:65, DRB1*11:66, DRB1*11:67, DRB1*11:68, DRB1*11:69, DRB1*11:70
    and DRB1*11:72. The sequence shown is that of DRB1*11:01
    Polymorphism: Allele DRB1*11:01 is associated with self-limiting hepatitis C virus (HCV) infections [MIM:609532]
    Polymorphism: The following alleles of DRB1-12 are known: DRB1*12:01, DRB1*12:02, DRB1*12:03, DRB1*12:04, DRB1*12:05,
    DRB1*12:06, DRB1*12:07, DRB1*12:08, DRB1*12:09, DRB1*12:10, DRB1*12:11, DRB1*12:12, DRB1*12:13, DRB1*12:14,
    DRB1*12:15, DRB1*12:16, DRB1*12:17, DRB1*12:18 and DRB1*12:19. The sequence shown is that of DRB1*12:01
    Polymorphism: The following alleles of DRB1-13 are known: DRB1*13:01, DRB1*13:02, DRB1*13:03, DRB1*13:04, DRB1*13:05,
    DRB1*13:06, DRB1*13:07, DRB1*13:08, DRB1*13:09, DRB1*13:10, DRB1*13:11, DRB1*13:12, DRB1*13:13, DRB1*13:14,
    DRB1*13:15, DRB1*13:16, DRB1*13:17, DRB1*13:18, DRB1*13:19, DRB1*13:20, DRB1*13:21, DRB1*13:22, DRB1*13:23,
    DRB1*13:24, DRB1*13:25, DRB1*13:26, DRB1*13:27, DRB1*13:28, DRB1*13:29, DRB1*13:30, DRB1*13:31, DRB1*13:32,
    DRB1*13:33, DRB1*13:34, DRB1*13:35, DRB1*13:36, DRB1*13:37, DRB1*13:38, DRB1*13:39, DRB1*13:40, DRB1*13:41,
    DRB1*13:42, DRB1*13:43, DRB1*13:44, DRB1*13:45, DRB1*13:46, DRB1*13:47, DRB1*13:48, DRB1*13:49, DRB1*13:50,
    DRB1*13:51, DRB1*13:52, DRB1*13:53, DRB1*13:54, DRB1*13:55, DRB1*13:56, DRB1*13:57, DRB1*13:58, DRB1*13:59,
    DRB1*13:60, DRB1*13:61, DRB1*13:62, DRB1*13:63, DRB1*13:64, DRB1*13:65, DRB1*13:66, DRB1*13:67, DRB1*13:68,
    DRB1*13:69, DRB1*13:70, DRB1*13:71, DRB1*13:72, DRB1*13:73, DRB1*13:74, DRB1*13:75, DRB1*13:76, DRB1*13:77,
    DRB1*13:78, DRB1*13:79, DRB1*13:80, DRB1*13:81, DRB1*13:82, DRB1*13:83, DRB1*13:84, DRB1*13:85, DRB1*13:86, DRB1*13:87
    and DRB1*13:88. The sequence shown is that of DRB1*13:01
    Polymorphism: The following alleles of DRB1-14 are known: DRB1*14:01, DRB1*14:02, DRB1*14:03, DRB1*14:04, DRB1*14:05,
    DRB1*14:06, DRB1*14:07, DRB1*14:08, DRB1*14:09, DRB1*14:10, DRB1*14:11, DRB1*14:12, DRB1*14:13, DRB1*14:14,
    DRB1*14:15, DRB1*14:16, DRB1*14:17, DRB1*14:18, DRB1*14:19, DRB1*14:20, DRB1*14:21, DRB1*14:22, DRB1*14:23,
    DRB1*14:24, DRB1*14:25, DRB1*14:26, DRB1*14:27, DRB1*14:28, DRB1*14:29, DRB1*14:30, DRB1*14:31, DRB1*14:32,
    DRB1*14:33, DRB1*14:34, DRB1*14:35, DRB1*14:36, DRB1*14:37, DRB1*14:38, DRB1*14:39, DRB1*14:40, DRB1*14:41,
    DRB1*14:42, DRB1*14:43, DRB1*14:44, DRB1*14:45, DRB1*14:46, DRB1*14:47, DRB1*14:48, DRB1*14:49, DRB1*14:50,
    DRB1*14:51, DRB1*14:52, DRB1*14:53, DRB1*14:54, DRB1*14:55, DRB1*14:56, DRB1*14:57, DRB1*14:58, DRB1*14:59,
    DRB1*14:60, DRB1*14:61, DRB1*14:62, DRB1*14:63, DRB1*14:64, DRB1*14:65, DRB1*14:67, DRB1*14:68, DRB1*14:69,
    DRB1*14:70, DRB1*14:71, DRB1*14:72, DRB1*14:73, DRB1*14:74, DRB1*14:75, DRB1*14:76, DRB1*14:77, DRB1*14:78,
    DRB1*14:79, DRB1*14:80, DRB1*14:81, DRB1*14:82, DRB1*14:83, DRB1*14:84 and DRB1*14:85. The sequence shown is that of
    DRB1*14:01
    Polymorphism: The following alleles of DRB1-15 are known: DRB1*15:01, DRB1*15:02, DRB1*15:03, DRB1*15:04, DRB1*15:05,
    DRB1*15:06, DRB1*15:07, DRB1*15:08, DRB1*15:09, DRB1*15:10, DRB1*15:11, DRB1*15:12, DRB1*15:13, DRB1*15:14,
    DRB1*15:15, DRB1*15:16, DRB1*15:18, DRB1*15:19, DRB1*15:20, DRB1*15:21, DRB1*15:22, DRB1*15:23, DRB1*15:24,
    DRB1*15:25, DRB1*15:26, DRB1*15:27, DRB1*15:28, DRB1*15:29, DRB1*15:30, DRB1*15:31 and DRB1*15:32. The sequence shown
    is that of DRB1*15:01
    Polymorphism: The following alleles of DRB1-16 are known: DRB1*16:01; DRB1*16:02; DRB1*16:03; DRB1*16:04; DRB1*16:05;
    DRB1*16:07; DRB1*16:08; DRB1*16:09; DRB1*16:10; DRB1*16:11 and DRB1*16:12. The sequence shown is that of DRB1*16:02


    10/2620 NCBI SNPs in HLA-DRB1 are shown (see all 2620)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs10598081,2
    		C--32291334(-) GGGCTG/ATTCAT 2 /L syn11Minor allele frequency- A:0.00NA 2
    rs38301261,2
    		C--32291340(-) GGGGCA/CGGGCT 2 A syn10--------
    rs178796201,2
    		C--32294676(-) CACCTA/TCTGCA 2 Y F mis10--------
    rs178840431,2
    		C--32294677(-) ACACCC/G/TACTGC 3 H D Y mis10--------
    rs168228531,2
    		C,F--32294697(-) GCAGGA/C/GGCGGG 3 K T R mis12MN 368
    rs178786221,2
    		C--32294750(-) GAGCTA/GGGGCG 2 L syn10--------
    rs10595821,2
    		C,F,--32294757(-) GGTGAC/G/TGGAGC 3 T R M mis11EU 401
    rs178820141,2
    		C--32294869(-) AGAGGA/GAGTGT 2 K E mis10--------
    rs719457571,2
    		C,--32546054(+) CTCTC-/AGAT  
                AGAAC     		3 -- ds50010--------
    rs412871501,2
    		C,--32546056(+) CTCAGA/GTAGAA 3 -- ds50014Minor allele frequency- G:0.30WA NA EA 360

    HapMap Linkage Disequilibrium report for HLA-DRB1 (32546546 - 32557625 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 22 variations for HLA-DRB1
         15/20 CNVs (see all 20): 7567 69436 37840 69447 69420 4767 4493 64476 3603 69431 69407 69452 81340 69421 93647
         2 Indels: 33807 12831
    Human Gene Mutation Database (HGMD): HLA-DRB1

    Locus Specific Mutation Databases (LSDB): HLA-DRB1

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HLA-DRB1
    DNA2.0 Custom Variant and Variant Library Synthesis for HLA-DRB1

    Disorders / Diseases
    for HLA-DRB1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    HLA-DRB1 for disorders           About GeneDecksing

    OMIM gene information: 142857   
    OMIM disorders: 181000  126200  180300  
    UniProtKB/Swiss-Prot: 2B1G_HUMAN, Q29974
  • Genetic variation in HLA-DRB1 is a cause of susceptibility to sarcoidosis type 1 (SS1) [MIM:181000].
    • Sarcoidosis is an idiopathic, systemic, inflammatory disease characterized by the formation of immune granulomas in
    involved organs. Granulomas predominantly invade the lungs and the lymphatic system, but also skin, liver, spleen,
    eyes and other organs may be involved

    20/358 diseases for HLA-DRB1 (see all 358):    About MalaCards
    vogt-koyanagi-harada disease    pure red-cell aplasia    sarcoidosis, susceptibility l, 1    kleine-levin syndrome
    alpha 1-antitrypsin deficiency    21-hydroxylase deficiency    graft versus host disease    pars planitis
    adult-onset still's disease    porphyria cutanea tarda    polymyalgia rheumatica    epidermolysis bullosa acquisita
    relapsing-remitting multiple sclerosis    churg-strauss syndrome    rhizomelic pseudopolyarthritis    avascular necrosis of femoral head
    paroxysmal nocturnal hemoglobinuria    toxic epidermal necrolysis    chronic inflammatory demyelinating polyradiculoneuropathy    stevens-johnson syndrome

    9 diseases from the University of Copenhagen DISEASES database for HLA-DRB1:
    Hypersensitivity reaction type II disease     Rheumatoid arthritis     Diabetes mellitus     Hyperthyroidism
    Connective tissue disease     Thyroiditis     Skin disease     Leprosy
    Multiple sclerosis

    10/53 Novoseek disease relationships for HLA-DRB1 gene (see all 53)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    rheumatoid arthritis 66.3 64 1416553 (3), 16277691 (2), 16385499 (2), 10765919 (2) (see all 44)
    genetic susceptibility 65.2 8 17055211 (1), 17047287 (1), 17309132 (1), 18004301 (1) (see all 8)
    polymyalgia rheumatica 58.1 10 10225816 (2), 8147928 (2), 9458210 (2), 15305244 (2) (see all 5)
    diabetes mellitus insulin-dependent 50.2 2 10680451 (1), 7817375 (1)
    autoimmune diseases 49.3 5 16362107 (1), 19117368 (1), 16198136 (1), 1617108 (1) (see all 5)
    vogt-koyanagi-harada disease 46.6 2 7906684 (1), 15603876 (1)
    autoimmunity 44.1 4 16385499 (1), 17987563 (1), 15120192 (1), 8675578 (1)
    hepatitis autoimmune 44 3 1350267 (2), 9672174 (1)
    pemphigus foliaceus 36.9 1 9027963 (1)
    diabetes autoimmune 35.6 2 10333055 (1), 18279373 (1)

    Genetic Association Database (GAD): HLA-DRB1
    Human Genome Epidemiology (HuGE) Navigator: HLA-DRB1 (1845 documents)

    Export disorders for HLA-DRB1 gene to outside databases

    Publications
    for HLA-DRB1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HLA-DRB1 gene, integrated from 9 sources (see all 2487) (see top 10):
    (articles sorted by number of sources associating them with HLA-DRB1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. [Determination of HLA-DRB1 gene polymorphism in Luoba ethnic group of Tibet] (PubMed id 15898419)1, 4, 9 Kang L.L....Li S.B. (2005)
    2. Influence of HLA-DRB1 and TNF microsatellite polymorphisms on the expression of extraarticular manifestations in rheumatoid arthritis patients from northwest Spain. (PubMed id 11791643)1, 4, 9 Mattey D.L....Ollier W.E. (2001)
    3. [Possible association between HLA-HRB1 and DQB1 genes frequency and susceptibility or resistance to Helicobacter pylori infection in Kunming Yi ethnic group children] (PubMed id 15833172)1, 4, 9 Huang Y.K....Zhou L.F. (2005)
    4. [Association of HLA-A, B, and DR haplotypes with genotype in Chinese children with systemic lupus erythematosus] (PubMed id 14748996)1, 4, 9 Li C.F....Jiang Z.F. (2003)
    5. [Polymorphism of length of tetranucleotide repeat from the 5'-side from the myelin basic protein gene in multiple sclerosis in Russians] (PubMed id 14714495)1, 4, 9 Andreevskii T.V....Favorova O.O. (2003)
    6. HLA-DRB1 and HLA-DQB1 polymorphisms in Pacific Islands populations. (PubMed id 12144623)1, 4, 9 Velickovic Z.M....Carter J.M. (2002)
    7. Collagenase-1 (MMP-1) and HLA-DRB1 gene polymorphisms in rheumatoid arthritis: a prospective longitudinal study. (PubMed id 11824952)1, 4, 9 Constantin A....Cantagrel A. (2002)
    8. Association between protein tyrosine phosphatase 22 variant R620W in conjunction with the HLA-DRB1 shared epitope and humoral autoimmunity to an immunodominant epitope of cartilage-specific type II collagen in early rheumatoid arthritis. (PubMed id 16385499)1, 4, 9 Burkhardt H....Reis A. (2006)
    9. [Polymorphism of HLA-A,-B and DRB1 in Han population of Shanxi province] (PubMed id 16215957)1, 4, 9 Lan T....Wang G.Q. (2005)
    10. The impact of HLA-DRB1 genes on extra-articular disease manifestations in rheumatoid arthritis. (PubMed id 16277691)1, 4, 9 Turesson C....Matteson E.L. (2005)
    11. Epistatic interactions between HLA-DRB1 and interleukin 4, but not interferon-gamma, increase susceptibility to giant cell arteritis. (PubMed id 15570643)1, 4, 9 Amoli M.M....Ollier W.E. (2004)
    12. Molecular analyses of HLA-DRB1, -DPB1, and -DQB1 in Jing ethnic minority of Southwest China. (PubMed id 12878363)1, 4, 9 Lin J.H....Xu A.L. (2003)
    13. DRB1, DQA1, DQB1 genes in Turkish children with rheumatic fever. (PubMed id 15789899)1, 4, 9 Hallioglu O....Ozer S. (2005)
    14. DQB1*0602 allele shows a strong association with multiple sclerosis in patients in Malaga, Spain. (PubMed id 15083289)1, 4, 9 Fernandez O....de Ramon E. (2004)
    15. A NOTCH4 association with multiple sclerosis is secondary to HLA-DR*1501. (PubMed id 14651518)1, 4, 9 Duvefelt K....Hillert J. (2004)
    16. [Association between HLA-DRB1, DQB1 genes and pemphigus vulgaris in Chinese Hans] (PubMed id 12579512)1, 4, 9 Zhou S.H....Ye S.Z. (2003)
    17. HLA class II and TNF genes in African Americans from the Southeastern United States: regional differences in allele frequencies. (PubMed id 12770797)1, 4, 9 Kuffner T....McNicholl J. (2003)
    18. Association of the HLA-DRB1 gene with susceptibility to aortoarteritis in a Chinese Han population. (PubMed id 12358152)1, 4, 9 Dang A....Liu L. (2002)
    19. Association of DRB1*04-DQB1*0301 haplotype and lack of association of two polymorphic sites at CTLA-4 gene with Hashimoto's thyroiditis in an Italian population. (PubMed id 11288988)1, 4, 9 Petrone A....Buzzetti R. (2001)
    20. Association of HLA-DRB1(*)07 and DRB1(*)04 to citrus red mite (Panonychus citri) and house dust mite sensitive asthma. (PubMed id 11069565)1, 4, 9 Cho S.H....Min K.U. (2000)
    21. Tumor necrosis factor, tumor necrosis factor receptors type 1 and 2, lymphotoxin-alpha, and HLA-DRB1 gene polymorphisms in human T-cell lymphotropic virus type I associated myelopathy. (PubMed id 11163081)1, 4, 9 Nishimura M....Uchiyama T. (2000)
    22. MHC class II, tumour necrosis factor alpha, and lymphotoxin alpha gene haplotype associations with serological subsets of systemic lupus erythematosus. (PubMed id 16107511)1, 4, 9 McHugh N.J....Welsh K. (2006)
    23. HLA-B, -DRB1/3/4/5, and -DQB1 gene polymorphisms in human immunodeficiency virus-related Kaposi's sarcoma. (PubMed id 15902698)1, 4, 9 Dorak M.T....Kaslow R.A. (2005)
    24. Genetic predictors of coronary heart disease risk factors in premenopausal African-American women. (PubMed id 15825968)1, 4, 9 Giger J.N....Acton R.T. (2005)
    25. Association of the major histocompatibility complex with response to infliximab therapy in rheumatoid arthritis patients. (PubMed id 15077289)1, 4, 9 Martinez A....Fernandez-Gutierrez B. (2004)
    26. HLA-DRB1 and -DQB1 alleles in mestizo patients with Vogt-Koyanagi-Harada's disease in Southern California. (PubMed id 15603876)1, 4, 9 Levinson R.D....Holland G.N. (2004)
    27. [Study on the polymorphisme of human leucocyte antigen-DRB1, -DQA1 and -DQB1 alleles in patients with hepatitis B] (PubMed id 15231205)1, 4, 9 Jiang Y.G. and Wang Y.M. (2004)
    28. HLA-DRB1 alleles and HLA-DRB1 shared epitopes are markers for juvenile rheumatoid arthritis subgroups in Colombian mestizos. (PubMed id 15120191)1, 4, 9 Garavito G....Jaraquemada D. (2004)
    29. Heterogeneity in the magnitude of the insulin gene effect on HLA risk in type 1 diabetes. (PubMed id 15561961)1, 4, 9 Motzo C....Cucca F. (2004)
    30. Diabetes mellitus in adults: association of HLA DRB1 and DQB1 diabetes risk alleles with GADab presence and C-peptide secretion. (PubMed id 15388265)1, 4, 9 Novota P....Andel M. (2004)
    31. HLA class II typing in newborns reveals a low frequency of the DRB1*04 allele and a high frequency of DRB1*11 allele in three regions of continental Italy. (PubMed id 15120192)1, 4, 9 Galgani A....Buzzetti R. (2004)
    32. Analysis of major histocompatibility complex and CTLA-4 alleles in Brazilian patients with primary biliary cirrhosis. (PubMed id 12911663)1, 4, 9 Bittencourt P.L....Goldberg A.C. (2003)
    33. Novel association of HLA-haplotypes with primary sclerosing cholangitis (PSC) in a southern European population. (PubMed id 14567462)1, 4, 9 Neri T.M....Okolicsanyi L. (2003)
    34. Influence of MHC class II in susceptibility to beryllium sensitization and chronic beryllium disease. (PubMed id 14662898)1, 4, 9 Maier L.A....Newman L.S. (2003)
    35. Association of HLA class I and II alleles and extended haplotypes with nasopharyngeal carcinoma in Taiwan. (PubMed id 12464650)1, 4, 9 Hildesheim A....Erlich H.A. (2002)
    36. The association between tumor necrosis factor, HLA-DR alleles, and IgE-mediated asthma in Taiwanese adolescents. (PubMed id 12169181)1, 4, 9 Lin Y.C....Guo Y.L. (2002)
    37. HLA associations in P. falciparum malaria patients from Mumbai, western India. (PubMed id 14686115)1, 4, 9 Shankarkumar U....Mohanty D. (2002)
    38. HLA-DR and DQB1 gene polymorphism in the North-western Colombian population. (PubMed id 12144632)1, 4, 9 Correa P.A....Anaya J.M. (2002)
    39. Molecular analysis of HLA-DRB1, DQA1, DQB1, DQ promoter polymorphism and extended class I/class II haplotypes in the Seri Indians from Northwest Mexico. (PubMed id 12144622)1, 4, 9 Alaez C....Gorodezky C. (2002)
    40. Association analysis of HLA-class II and class III gene polymorphisms in the susceptibility to mediterranean visceral leishmaniasis. (PubMed id 11334675)1, 4, 9 Meddeb-Garnaoui A....Dellagi K. (2001)
    41. HLA class II alleles in Chinese patients with hepatocellular carcinoma. (PubMed id 11318984)1, 4, 9 Donaldson P.T....Johnson P.J. (2001)
    42. HLA class I and class II allele and haplotype diversity in Martinicans. (PubMed id 11285127)1, 4, 9 Bera O....Semana G. (2001)
    43. MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation. (PubMed id 18305173)1, 2 De Gassart A....Gatti E. (2008)
    44. The association of CTLA4 polymorphism with type 1 diabetes is concentrated in patients complicated with autoimmune thyroid disease: a multicenter collaborative study in Japan. (PubMed id 16352685)1, 4 Ikegami H....Ogihara T. (2006)
    45. Association of the truncating splice site mutation in BTNL2 with multiple sclerosis is secondary to HLA-DRB1*15. (PubMed id 16321988)1, 4 Traherne J.A....Trowsdale J. (2006)
    46. Interaction of loci within the HLA region influences multiple sclerosis course in the Sardinian population. (PubMed id 16096810)1, 4 Marrosu M.G....Contu P. (2006)
    47. Molecular genetic studies on the compatibility of HLA class II alleles in patients with unexplained recurrent miscarriage in the Japanese population. (PubMed id 16122986)1, 4 Takakuwa K....Tanaka K. (2006)
    48. Interleukin-12p40 gene (IL-12B) polymorphism and Type 1 diabetes mellitus in Japanese: possible role in subjects without having high-risk HLA haplotypes. (PubMed id 16005098)1, 4 Yang J.M....Ishibashi S. (2006)
    49. The prevalence of human leukocyte antigen (HLA) DR/DQ/DP alleles in Kuwaiti children with oligoarticular juvenile idiopathic arthritis. (PubMed id 15703957)1, 4 Alsaeid K....Ayoub E.M. (2006)
    50. Association of HLA-DRB1*0901-DQB1*0303 haplotype with microscopic polyangiitis in Japanese. (PubMed id 16208405)1, 4 Tsuchiya N....Tokunaga K. (2006)
    51. HLA class I and class II frequencies in patients with cutaneous malignant melanoma from southeastern Spain: the role of HLA-C in disease prognosis. (PubMed id 16365741)1, 4 Campillo J.A....Alvarez-Lopez M.R. (2006)
    52. Human leukocyte antigen class II alleles in Caucasian women with primary biliary cirrhosis. (PubMed id 15713222)1, 4 Mullarkey M.E....Nelson J.L. (2005)
    53. Human leukocyte antigen and cytokine gene variants as predictors of recurrent Chlamydia trachomatis infection in high-risk adolescents. (PubMed id 15747244)1, 4 Wang C....Kaslow R.A. (2005)
    54. Sensitivity to bee venom antigen phospholipase A2: association with specific HLA class I and class II alleles and haplotypes in beekeepers and allergic patients. (PubMed id 16112029)1, 4 Sanchez-Velasco P....Leyva-Cobian F. (2005)
    55. Association between pemphigus vulgaris and human leukocyte antigen in Han nation of northeast China. (PubMed id 16261886)1, 4 Geng L....Chen H.D. (2005)
    56. Lack of association with the CD28/CTLA4/ICOS gene region among Norwegian multiple sclerosis patients. (PubMed id 16005527)1, 4 Lorentzen A.R....Harbo H.F. (2005)
    57. HLA-DR,DQ and APOE genotypes and gender influence in Sardinian primary progressive MS. (PubMed id 15699400)1, 4 Cocco E....Marrosu M.G. (2005)
    58. Major histocompatibility complex class II (HLA-DRB and -DQB) allele frequencies in Botswana: association with human immunodeficiency virus type 1 infection. (PubMed id 16148166)1, 4 Ndung'u T....Essex M. (2005)
    59. CT60 single nucleotide polymorphisms of the cytotoxic T-lymphocyte-associated antigen-4 gene region is associated with Graves' disease in an Italian population. (PubMed id 15785242)1, 4 Petrone A....Buzzetti R. (2005)
    60. Antigen presentation of the immunodominant T-cell epitope of the major mugwort pollen allergen, Art v 1, is associated with the expression of HLA-DRB1 *01. (PubMed id 15696102)1, 4 Jahn-Schmid B....Ebner C. (2005)
    61. Major histocompatibility complex and alveolar epithelial apoptosis in idiopathic pulmonary fibrosis. (PubMed id 16133177)1, 4 Falfan-Valencia R....Selman M. (2005)
    62. MHC microsatellite diversity and linkage disequilibrium among common HLA-A, HLA-B, DRB1 haplotypes: implications for unrelated donor hematopoietic transplantation and disease association studies. (PubMed id 16029431)1, 4 Malkki M....Petersdorf E. (2005)
    63. Residual insulin secretion at diagnosis of type 1 diabetes is independently associated with both, age of onset and HLA genotype. (PubMed id 15786423)1, 4 Petrone A....Buzzetti R. (2005)
    64. Association of HLA-DRB1, DQB1 alleles with chronic urticaria. (PubMed id 16201295)1, 4 Chen J....Xiong P. (2005)
    65. The DR4-DQ8 haplotype and a specific T cell receptor Vbeta T cell subset are associated with absence of allergy to Can f 1. (PubMed id 15969672)1, 4 Kinnunen T....Virtanen T. (2005)
    66. Association between human leukocyte antigen class II alleles and genotype of Borrelia burgdorferi in patients with early lyme disease. (PubMed id 16267776)1, 4 Wormser G.P....Klempner M. (2005)
    67. HLA allelic variants encoding DR11 in diffuse and limited systemic sclerosis in Caucasian women. (PubMed id 15572392)1, 4 Loubiere L.S....Nelson J.L. (2005)
    68. Interleukin 18 and sICAM-1 serum levels in families with type 1 diabetes mellitus. (PubMed id 16358956)1, 4 Mironczuk K....Gorska M. (2005)
    69. [Analysis of HLA alleles polymorphism in Chinese patients with primary biliary cirrhosis] (PubMed id 15975271)1, 4 Liu H.Y....Zhong R.Q. (2005)
    70. Association of HLA-DR and -DQ genes with Graves disease in Koreans. (PubMed id 15993720)1, 4 Park M.H....Cho B.Y. (2005)
    71. Immunogenetics of primary Sjogren's syndrome in Colombians. (PubMed id 15846589)1, 4 Anaya J.M....Correa P.A. (2005)
    72. Anti-caspase-8 autoantibody response in silicosis patients is associated with HLA-DRB1, DQB1 and DPB1 alleles. (PubMed id 15703453)1, 4 Ueki A....Kusaka M. (2005)
    73. A case-control study to examine HLA haplotype associations in patients with posttreatment chronic Lyme disease. (PubMed id 16107953)1, 4 Klempner M.S....Schmid C. (2005)
    74. [Relationship between pneumoconiosis and the polymorphisms of HLA-DRB1*, DQB1* genes] (PubMed id 16188098)1, 4 Fan X.Y....Ma Q.K. (2005)
    75. Polymorphism of human leukocyte antigen-DRB1, -DQB1, and -DPB1 genes of Shandong Han population in China. (PubMed id 15982255)1, 4 Zhou L....Xu A. (2005)
    76. The human leucocyte antigen-DRB1*1302-DQB1*0609-DPB1*0201 haplotype may be a strong genetic marker for aspirin-induced urticaria. (PubMed id 15784113)1, 4 Kim S.H....Park H.S. (2005)
    77. Susceptibility alleles and haplotypes of human leukocyte antigen DRB1, DQA1, and DQB1 in autoimmune polyglandular syndrome type III in Japanese population. (PubMed id 16254435)1, 4 Hashimoto K....Nakamura T. (2005)
    78. Development of a new HLA-DRB real-time PCR typing method. (PubMed id 15620466)1, 4 Casamitjana N....Palou E. (2005)
    79. Association of SLC11A1 (NRAMP1) with persistent oligoarticular and polyarticular rheumatoid factor-negative juvenile idiopathic arthritis in Finnish patients: haplotype analysis in Finnish families. (PubMed id 15641099)1, 4 Runstadler J.A....Seldin M.F. (2005)
    80. [Study on the correlation between acute lymphoblastic leukemia and HLA genes in southern China Han population.] (PubMed id 15854278)1, 4 Gao S.Q....Wu G.G. (2005)
    81. Estimation of diabetes risk in Brazilian population by typing for polymorphisms in HLA-DR-DQ, INS and CTLA-4 genes. (PubMed id 16276008)1, 4 Hauache O.M....Ilonen J. (2005)
    82. New strategies for efficient typing of HLA class-II loci DQB1 and DRB1 by using Pyrosequencing. (PubMed id 15663743)1, 4 Entz P....Nagy M. (2005)
    83. Lymphoid tyrosine phosphatase (PTPN22/LYP) variant and Graves' disease in a Polish population: association and gene dose-dependent correlation with age of onset. (PubMed id 15943829)1, 4 Skorka A....Ploski R. (2005)
    84. Association of HLA class I and class II polymorphisms with age-related macular degeneration. (PubMed id 15851575)1, 4 Goverdhan S.V....Lotery A.J. (2005)
    85. Relationship between HLA-DR, HLA-DQ alleles and MEFV gene mutations in familial Mediterranean fever (FMF) patients. (PubMed id 16245224)1, 4 Kinikli G....Tokgoz G. (2005)
    86. Population frequency of HLA haplotypes contributes to the prevalence difference of multiple sclerosis in Ireland. (PubMed id 16158194)1, 4 McGuigan C....Hutchinson M. (2005)
    87. Does genotype mask the relationship between psychological factors and immune function? (PubMed id 15664787)1, 4 Smith A....Lloyd A. (2005)
    88. Association of clinical features with HLA in chronic pulmonary thromboembolism. (PubMed id 15640334)1, 4 Tanabe N....Kuriyama T. (2005)
    89. Contribution of selective HLA-DRB1/DQB1 alleles and haplotypes to the genetic susceptibility of type 1 diabetes among Lebanese and Bahraini Arabs. (PubMed id 15985473)1, 4 Al-Jenaidi F.A....Almawi W.Y. (2005)
    90. Linkage disequilibrium between human leukocyte antigen (HLA) class II and HLA-G--possible implications for human reproduction and autoimmune disease. (PubMed id 15993714)1, 4 Hviid T.V. and Christiansen O.B. (2005)
    91. Optic neuritis, multiple sclerosis and human leukocyte antigen: results of a 4-year follow-up study. (PubMed id 15613143)1, 4 Amirzargar A.A....Nikbin B. (2005)
    92. Association between psoriasis vulgaris and MHC-DRB, -DQB genes as a contribution to disease diagnosis. (PubMed id 15908298)1, 4 Cardoso C.B....Kraemer M.H. (2005)
    93. Analysis of B- and T-cell clonality and HLA class II alleles in patients with idiopathic thrombocytopenic purpura: correlation with Helicobacter pylori infection and response to eradication treatment. (PubMed id 16011982)1, 4 Veneri D....Franchini M. (2005)
    94. Allelic and haplotypic diversity of HLA-A, -B, -C, -DRB1, and -DQB1 genes in the Korean population. (PubMed id 15853898)1, 4 Lee K.W....Yang S.Y. (2005)
    95. Genetic interaction among three genomic regions creates distinct contributions to early- and late-onset type 1 diabetes mellitus. (PubMed id 16390390)1, 4 Felner E.I....White P.C. (2005)
    96. Association of CD40 gene polymorphism (C-1T) with susceptibility and phenotype of Graves' disease. (PubMed id 16279844)1, 4 Kurylowicz A....Bednarczuk T. (2005)
    97. The association between HLA DR, DQ antigens, and vulval lichen sclerosus in the UK: HLA DRB112 and its associated DRB112/DQB10301/04/09/010 haplotype confers susceptibility to vulval lichen sclerosus, and HLA DRB10301/04 and its associated DRB10301/04/DQB10201/02/03 haplotype protects from vulval lichen sclerosus. (PubMed id 16297186)1, 4 Gao X.H....Wojnarowska F. (2005)
    98. [Correlation between the polymorphism of HLA-A, -B, and -DRB1 alleles and susceptibility to leukemia] (PubMed id 16143070)1, 4 Zhou L.X. and Zhao L. (2005)
    99. Analysis of HLA class I and class II gene polymorphisms in Japanese patients with human T-cell lymphotropic virus type 1-associated uveitis. (PubMed id 16019679)1, 4 Kaminagayoshi T....Sakamoto T. (2005)
    100. Impact of HLA class I high-resolution mismatches on chronic graft-versus-host disease and survival of patients given hematopoietic stem cell grafts from unrelated donors. (PubMed id 15531903)1, 4 Greinix H.T....Fischer G.F. (2005)
    101. Human leukocyte antigen-DQB1 and -DRB1 associations in patients with idiopathic sudden sensorineural hearing loss from a defined population of Northwest Spain. (PubMed id 16303674)1, 4 Amor-Dorado J.C....Gonzalez-Gay M.A. (2005)
    102. Maternal HLA class II compatibility in men with systemic lupus erythematosus. (PubMed id 16142706)1, 4 Stevens A.M....Nelson J.L. (2005)
    103. Function associated transforming growth factor-beta gene polymorphism in chronic beryllium disease. (PubMed id 15750822)1, 4 Gaede K.I....Muller-Quernheim J. (2005)
    104. Frequency of DRB1-DQB1 two-locus haplotypes in tuberculosis: preliminary report. (PubMed id 15958261)1, 4 Dubaniewicz A....Szczerkowska Z. (2005)
    105. Retrovirus-like long-terminal repeat DQ-LTR13 and genetic susceptibility to type 1 diabetes and autoimmune Addison's disease. (PubMed id 15734871)1, 4 Gambelunghe G.... . (2005)
    106. [Studies on the association of human leukocyte antigen class II alleles with advanced hepatosplenic schistosomiasis japonica] (PubMed id 16042197)1, 4 Zhang J.H....Long X.C. (2005)
    107. HLA class I and II polymorphisms in Azores show different settlements in Oriental and Central islands. (PubMed id 16101833)1, 4 Spinola H....Bruges-Armas J. (2005)
    108. An investigation of NOS2A promoter polymorphisms in Australian multiple sclerosis patients. (PubMed id 15856071)1, 4 Bugeja M.J....Stewart G.J. (2005)
    109. Association between human leukocytes antigen alleles and chronic hepatitis C virus infection in the Korean population. (PubMed id 16343061)1, 4 Yoon S.K....Kim T.G. (2005)
    110. [Study on correlation between histocompatibility leukocyte antigen class II gene and gestational diabetes mellitus] (PubMed id 16277897)1, 4 Zhao M.L....Qi W.J. (2005)
    111. Human leukocyte antigen class II alleles and rubella-specific humoral and cell-mediated immunity following measles-mumps-rubella-II vaccination. (PubMed id 15655774)1, 4 Ovsyannikova I.G....Poland G.A. (2005)
    112. Predisposing HLA-DQ2 and HLA-DQ8 haplotypes of coeliac disease and associated enteropathy in microscopic colitis. (PubMed id 16292086)1, 4 Fernandez-Banares F....Viver J.M. (2005)
    113. Sarcoidosis is associated with a truncating splice site mutation in BTNL2. (PubMed id 15735647)1, 4 Valentonyte R....Schreiber S. (2005)
    114. Association of chronic fatigue syndrome with human leucocyte antigen class II alleles. (PubMed id 16049290)1, 4 Smith J....Mattey D.L. (2005)
    115. Contribution of MHC class I chain-related A (MICA) gene polymorphism to genetic susceptibility for systemic lupus erythematosus. (PubMed id 15522921)1, 4 Gambelunghe G....Falorni A. (2005)
    116. Association of extrahepatic manifestations with HLA class II alleles and with virus genotype in HCV infected patients. (PubMed id 16180280)1, 4 Sebastiani G.D....Galeazzi M. (2005)
    117. Identification of HLA-DQalpha and -DRbeta residues associated with susceptibility and protection to epithelial ovarian cancer. (PubMed id 15935893)1, 4 Monos D.S....Platsoucas C.D. (2005)
    118. HLA class II involvement in HIV-associated Toxoplasmic encephalitis development. (PubMed id 15885635)1, 4 Habegger de Sorrentino A....Salomon H. (2005)
    119. D6S265*15 marks a DRB1*15, DQB1*0602 haplotype associated with attenuated protection from type 1 diabetes mellitus. (PubMed id 16320082)1, 4 Valdes A.M.... . (2005)
    120. Does a central MHC gene in linkage disequilibrium with HLA-DRB1*0401 affect susceptibility to type 1 diabetes? (PubMed id 15858601)1, 4 Windsor L....Price P. (2005)
    121. Glutamic acid decarboxylase autoantibody prevalence and association with HLA genotype in patients with younger-onset type 1 diabetes and proliferative diabetic retinopathy. (PubMed id 16157380)1, 4 Mimura T....Hori S. (2005)
    122. A novel HLA allele, DRB1*1609, identified in the Chinese Han population*. (PubMed id 16101839)1, 2 Miao K.R....KuKuruga D. (2005)
    123. The Fc gammaRIIa polymorphism R/H131, autoantibodies against the platelet receptors GPIb alpha and Fc gammaRIIa and a risk for thromboembolism in lupus anticoagulant patients. (PubMed id 15735807)1, 4 Schallmoser K....Panzer S. (2005)
    124. Severe pulmonary sarcoidosis is strongly associated with the haplotype HLA-DQB1*0602-DRB1*150101. (PubMed id 16112030)1, 4 Voorter C.E....van den Berg-Loonen E.M. (2005)
    125. Relationship of human leukocyte antigen class II genes with the susceptibility to hepatitis B virus infection and the response to interferon in HBV-infected patients. (PubMed id 16237774)1, 4 Han Y.N....Zhu W. (2005)
    126. Slowly progressing form of type 1 diabetes mellitus in children: genetic analysis compared with other forms of diabetes mellitus in Japanese children. (PubMed id 16390391)1, 4 Ohtsu S....Matsuura N. (2005)
    127. HLA class II allele control of HPV load in carcinoma in situ of the cervix uteri. (PubMed id 15906352)1, 4 Beskow A.H....Gyllensten U.B. (2005)
    128. Association of HLA-DR and HLA-DQ genes with susceptibility to pulmonary tuberculosis in Koreans: preliminary evidence of associations with drug resistance, disease severity, and disease recurrence. (PubMed id 16386650)1, 4 Kim H.S....Shim Y.S. (2005)
    129. Genetic analysis of the HLA region of Japanese patien ts with type 1 autoimmune hepatitis. (PubMed id 15763345)1, 4 Yoshizawa K....Kiyosawa K. (2005)
    130. HLA class II alleles and measles virus-specific cytokine immune response following two doses of measles vaccine. (PubMed id 15712014)1, 4 Ovsyannikova I.G....Poland G.A. (2005)
    131. HLA class II DPB1, DQA1, DQB1, and DRB1 genotypic associations with occupational allergic cough to Bunashimeji mushroom. (PubMed id 15853900)1, 4 Suzuki K....Sato N. (2005)
    132. Extensive polymorphisms of LILRB1 (ILT2, LIR1) and their association with HLA-DRB1 shared epitope negative rheumatoid arthritis. (PubMed id 16014635)1, 4 Kuroki K....Tokunaga K. (2005)
    133. A recombined haplotype in the major histocompatibility region contains a cluster of genes conferring high susceptibility to ulcerative colitis in the Spanish population. (PubMed id 16116311)1, 4 Fernandez L....Martinez A. (2005)
    134. The effect of HLA class II, insulin and CTLA4 gene regions on the development of humoral beta cell autoimmunity. (PubMed id 16025255)1, 4 Hermann R....Ilonen J. (2005)
    135. HLA-DRB1 and -DQB1 alleles and gene polymorphisms of selected cytokines in systemic lupus erythematosus. (PubMed id 15449022)1, 4 Hrycek A....Szkrobka W. (2005)
    136. HLA alleles and risk of cervical intraepithelial neoplasia among southwestern American Indian women. (PubMed id 16386646)1, 4 Schiff M.A....Becker T.M. (2005)
    137. Association of HLA-DR, -DQ genotype and CTLA-4 gene polymorphism with Graves' disease in Japanese children. (PubMed id 15640608)1, 4 Iwama S....Sugihara S. (2005)
    138. Clinical characteristics, beta-cell function, HLA class II and mutations in MODY genes in non-paediatric subjects with Type 1 diabetes without pancreatic autoantibodies. (PubMed id 15660729)1, 4 Aguilera E....Conget I. (2005)
    139. [Immunogenetic analysis of human leukocyte antigen DRB1, DQB1 locus among Han ethnic children with Helicobacter pylori infection in Kunming] (PubMed id 15941540)1, 4 Wen G.S....Zhou L.F. (2005)
    140. Association of HLA DQB1 0602 in sarcoidosis patients with small fiber neuropathy. (PubMed id 16053028)1, 4 Voorter C.E....van den Berg-Loonen E.M. (2005)
    141. HLA DR/DQ alleles and risk of type I diabetes in childhood: a population-based case-control study. (PubMed id 16096857)1, 4 Altobelli E....Papola F. (2005)
    142. HLA antigens in Greek children with allergic bronchial asthma. (PubMed id 15853903)1, 4 Parapanissiou E....Polymenidis Z. (2005)
    143. Genetic prediction of type 1 diabetes in a population with low frequency of HLA risk genotypes and low incidence of the disease (the DIABFIN study). (PubMed id 15037989)1, 4 Buzzetti R....Di Mario U. (2004)
    144. [The relation between the HLA-DRB1*1501 allele and the severity of multiple sclerosis in a sample of the Spanish population from the Balearic Islands: the influence exerted by sex] (PubMed id 14752708)1, 4 Zabay-Becerril J.M....Viader-Farre C. (2004)
    145. Killer cell immunoglobulin-like receptor genes in Latvian patients with type 1 diabetes mellitus and healthy controls. (PubMed id 15699512)1, 4 Nikitina-Zake L....Sanjeevi C.B. (2004)
    146. Complex genetic predisposition in adult and juvenile rheumatoid arthritis. (PubMed id 15018649)1, 4 Miterski B....Epplen J.T. (2004)
    147. Type 1 diabetes in Jewish Ethiopian immigrants in Israel: HLA class II immunogenetics and contribution of new environment. (PubMed id 15603874)1, 4 Zung A....Israel S. (2004)
    148. Molecular basis of predisposition to develop type 1 diabetes mellitus in North Indians. (PubMed id 15245369)1, 4 Rani R....Goswami R. (2004)
    149. Association of TAP2 gene polymorphisms in Chinese patients with rheumatoid arthritis. (PubMed id 14749980)1, 4 Yu M.C....Tsai F.J. (2004)
    150. Difference in pathogenesis between vitiligo vulgaris and halo nevi associated with vitiligo is supported by an HLA association study. (PubMed id 15140072)1, 4 de Vijlder H.C....Claas F.H. (2004)
    151. HLA-DRB1, -DQA1, and -DQB1 subtypes or ACE gene polymorphisms do not seem to be risk markers for severe retinopathy in younger Type 1 diabetic patients. (PubMed id 15019597)1, 4 Agardh E....Agardh C.D. (2004)
    152. Association of HLA-DQ5 and HLA-DR1 with sensitization to organic acid anhydrides. (PubMed id 15144476)1, 4 Jones M.G....Taylor A.N. (2004)
    153. HLA alleles, IFN-gamma responses to HPV-11 E6, and disease severity in patients with recurrent respiratory papillomatosis. (PubMed id 15336778)1, 4 Bonagura V.R....Reed E.F. (2004)
    154. Association of HLA Class I and Class II genes with bcr-abl transcripts in leukemia patients with t(9;22) (q34;q11). (PubMed id 15202948)1, 4 Mundhada S....Cano P. (2004)
    155. Amino acid residue at position 13 in HLA-DR beta chain plays a critical role in the development of Kaposi's sarcoma in AIDS patients. (PubMed id 15075536)1, 4 Gaya A....Whitby D. (2004)
    156. Hepatitis C virus-related hepatocellular carcinoma and B-cell lymphoma patients show a different profile of major histocompatibility complex class II alleles. (PubMed id 15556690)1, 4 De Re V....Boiocchi M. (2004)
    157. The co-inheritance of type 1 diabetes and multiple sclerosis in Sardinia cannot be explained by genotype variation in the HLA region alone. (PubMed id 15471889)1, 4 Marrosu M.G....Cucca F. (2004)
    158. [Alleles of HLA class II DRB1 of patients with essential hypertension in Yunnan Hans] (PubMed id 15192840)1, 4 Shao J.C....Cai X.M. (2004)
    159. Polymorphism of transporter associated with antigen presentation 1 as a potential determinant for severity of disease in recurrent respiratory papillomatosis caused by human papillomavirus types 6 and 11. (PubMed id 14976605)1, 4 Vambutas A....Steinberg B.M. (2004)
    160. A variant of childhood-onset myasthenia gravis: HLA typing and clinical characteristics in Japan. (PubMed id 15003812)1, 4 Shinomiya N....Segawa M. (2004)
    161. Patients with Goodpasture's disease have two normal COL4A3 alleles encoding the NC1 domain of the type IV collagen alpha 3 chain. (PubMed id 15199166)1, 4 Persson U....Segelmark M. (2004)
    162. Associations between human leukocyte antigen (HLA) alleles and very high levels of measles antibody following vaccination. (PubMed id 15121303)1, 4 Ovsyannikova I.G....Poland G.A. (2004)
    163. Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans. (PubMed id 14669136)1, 4 Oksenberg J.R....Hauser S.L. (2004)
    164. HLA-DRB1*04 and HLA-DQB1*03 association with the atrophic but not with the goitrous form of chronic autoimmune thyroiditis in a Brazilian population. (PubMed id 15305234)1, 4 Zantut-Wittmann D.E....Joao Pavin E. (2004)
    165. Combined association between IFN-gamma 3,3 homozygosity and DRB1*03 in Lofgren's syndrome patients. (PubMed id 15019280)1, 4 Wysoczanska B....Lange A. (2004)
    166. The association of HLA-DRB, DQA1, DQB1 alleles and haplotype frequency in Iranian patients with pulmonary tuberculosis. (PubMed id 15305487)1, 4 Amirzargar A.A....Nikbin B. (2004)
    167. Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences. (PubMed id 14730600)1, 4 Kochi Y....Yamamoto K. (2004)
    168. Association of MHC class I related gene B (MICB) to celiac disease. (PubMed id 15089901)1, 4 Gonzalez S....Lopez-Larrea C. (2004)
    169. A study of promoter and intronic markers of ApoI/Fas gene and the interaction with Fas ligand in relapsing multiple sclerosis. (PubMed id 15218339)1, 4 Lucas M....Izquierdo G. (2004)
    170. HLA class-I and HLA class-II phenotypic, gene and haplotypic frequencies in Tunisians by using molecular typing data. (PubMed id 15361135)1, 4 Ayed K....Gebuhrer L. (2004)
    171. Is TAP2*0102 allele involved in insulin-dependent diabetes mellitus (type 1) protection? (PubMed id 15336779)1, 4 Cesari M....Pabion M. (2004)
    172. Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis. (PubMed id 15248208)1, 4 van Gaalen F.A....de Vries R.R. (2004)
    173. MHC class I region plays a role in the development of diverse clinical forms of celiac disease in a Saharawi population. (PubMed id 15089899)1, 4 Lopez-Vazquez A....Lopez-Larrea C. (2004)
    174. Curative effects of interferon-alpha and HLA-DRB1 -DQA1 and -DQB1 alleles in chronic viral hepatitis B. (PubMed id 15237447)1, 4 Zang G.Q....Tang Z.H. (2004)
    175. Lack of association of the HLA-DRB1 shared epitope with rheumatoid nodules: an individual patient data meta-analysis of 3,272 Caucasian patients with rheumatoid arthritis. (PubMed id 15022316)1, 4 Gorman J.D....Criswell L.A. (2004)
    176. Haplotype associations of the MHC with psoriasis vulgaris in Chinese Hans. (PubMed id 15245541)1, 4 Yang S....Zhang X.J. (2004)
    177. HLA typing in Taiwanese patients with oral submucous fibrosis. (PubMed id 15061705)1, 4 Chen H.M....Chiang C.P. (2004)
    178. HLA-DQB1 alleles may influence the surface expression of DQ molecules in lymphomononuclear cells of type 1 diabetes mellitus patients. (PubMed id 15030582)1, 4 Fernandes A.P....Donadi E.A. (2004)
    179. Susceptibility gene for non-obstructive azoospermia in the HLA class II region: correlations with Y chromosome microdeletion and spermatogenesis. (PubMed id 14718045)1, 4 Takao T....Okuyama A. (2004)
    180. HLA and cytokine gene polymorphisms are independently associated with responses to hepatitis B vaccination. (PubMed id 15057902)1, 4 Wang C....Kaslow R.A. (2004)
    181. [Distribution features of HLA-DRB1 allele frequencies in normal cord blood donors of 3 438 Shandong Hans] (PubMed id 15228652)1, 4 Yan W.Y....Jiang X.F. (2004)
    182. Inheritance mode of multiple sclerosis: the effect of HLA class II alleles is stronger than additive. (PubMed id 15300424)1, 4 Boon M....te Meerman G.J. (2004)
    183. Influence of HLA on progression of optic neuritis to multiple sclerosis: results of a four-year follow-up study. (PubMed id 15471368)1, 4 Kheradvar A....Amirzargar A.A. (2004)
    184. Genetic screening for individuals at high risk for type 1 diabetes in the general population using HLA Class II alleles as disease markers. A comparison between three European populations with variable rates of disease incidence. (PubMed id 15250035)1, 4 Hermann R....Ilonen J. (2004)
    185. [Study of HLA polymorphism in the 6965 Han bone marrow registry donors] (PubMed id 15555263)1, 4 Wu G.G....Wang D.M. (2004)
    186. HLA-DQ6 and ingestion of contaminated water: possible gene-environment interaction in an outbreak of Leptospirosis. (PubMed id 15014429)1, 4 Lingappa J....McNicholl J. (2004)
    187. HLA class II genotype and factor VIII inhibitors in mild haemophilia A patients with an Arg593 to Cys mutation. (PubMed id 15357778)1, 4 Bril W.S....Voorberg J. (2004)
    188. [A study on the correlation between HLA-DR genes and susceptibility to pulmonary tuberculosis in a population of Han nationality from southern China] (PubMed id 15256088)1, 4 Liu Z.H....Liu Z.Q. (2004)
    189. Impact of shared epitope genotype and ethnicity on erosive disease: a meta-analysis of 3,240 rheumatoid arthritis patients. (PubMed id 14872482)1, 4 Gorman J.D....Criswell L.A. (2004)
    190. Association of polymorphic MHC microsatellites with GVHD, survival, and leukemia relapse in unrelated hematopoietic stem cell transplant donor/recipient pairs matched at five HLA loci. (PubMed id 15009808)1, 4 Li S....Inoko H. (2004)
    191. Strong linkage disequilibrium between HLA-B*3913 and DRB1*0807 in Brazilians. (PubMed id 15194283)1, 4 Moraes M.E....Moraes J.R. (2004)
    192. HLA-DRB1 and -DRB3 allele frequencies and haplotypic associations in Koreans. (PubMed id 15041167)1, 4 Song E.Y....Park M.H. (2004)
    193. Distribution of HLA class II (DRB1/DQB1) alleles and haplotypes among Bahraini and Lebanese Arabs. (PubMed id 15350494)1, 4 Almawi W.Y....Motala A.A. (2004)
    194. Molecular analysis of HLA allele frequencies and haplotypes in Baloch of Iran compared with related populations of Pakistan. (PubMed id 15496201)1, 4 Farjadian S....Inoko H. (2004)
    195. Possession of human leucocyte antigen DQ6 alleles and the rate of CD4 T-cell decline in human immunodeficiency virus-1 infection. (PubMed id 15096192)1, 4 Vyakarnam A....Peakman M. (2004)
    196. HLA class II polymorphism in Egyptian children with lymphomas. (PubMed id 15203870)1, 4 Al-Tonbary Y....El-Shawaf R. (2004)
    197. [Prediction of acute GVHD after umbilical cord blood transplantation by HLA three-dimensional structure matching] (PubMed id 15228651)1, 4 Xu R....Pei X.T. (2004)
    198. Lack of a strong association between HLA class II, tumour necrosis factor and transporter associated with antigen processing gene polymorphisms and virological response to alpha-interferon treatment in patients with chronic hepatitis C. (PubMed id 15548263)1, 4 Airoldi A....Pinzello G. (2004)
    199. Association of a specific haplotype across the genes MMP1 and MMP3 with radiographic joint destruction in rheumatoid arthritis. (PubMed id 15142265)1, 4 Dorr S....Keyszer G. (2004)
    200. [HLA polymorphism in a racially admixed sample of the population of Teresina, Piaui] (PubMed id 15666025)1, 4 Monte S.J....Gerbase-DeLima M. (2004)
    201. Human leukocyte antigen class II associations with systemic sclerosis in South Africans. (PubMed id 15104683)1, 4 Tikly M....Welsh K. (2004)
    202. HLA DRB1* and DQB1* allelic diversity among Nadars: a primitive south Indian Dravidian caste group. (PubMed id 15336786)1, 4 Shankarkumar U. and Sridharan B. (2004)
    203. The involvement of HLA -DRB1*, DQA1*, DQB1* and complement C4A loci in diagnosing systemic lupus erythematosus among Tunisians. (PubMed id 15310011)1, 4 Ayed K....Bardi R. (2004)
    204. HLA class II genotype influences the type of liver injury in drug-induced idiosyncratic liver disease. (PubMed id 15185301)1, 4 Andrade R.J....Hidalgo R. (2004)
    205. Genetic association of cutaneous neonatal lupus with HLA class II and tumor necrosis factor alpha: implications for pathogenesis. (PubMed id 15334474)1, 4 Clancy R.M....Buyon J.P. (2004)
    206. [Analysis of polymorphism of the HLA-DRB1 gene in populations from the Volga-Ural region] (PubMed id 15065436)1, 4 Khidiiatova I.M....Khusnutdinova E.K. (2004)
    207. Systemic lupus erythematosus in southern Spain: a comparative clinical and genetic study between Caucasian and Gypsy patients. (PubMed id 15645749)1, 4 Ramal L.M....Jimenez-Alonso J. (2004)
    208. HLA class II profile and distribution of HLA-DRB1 and HLA-DQB1 alleles and haplotypes among Lebanese and Bahraini Arabs. (PubMed id 15242955)1, 4 Almawi W.Y....Motala A.A. (2004)
    209. Genetic polymorphisms in tumor necrosis factor (TNF)-alpha and TNF-beta in a population-based study of systemic lupus erythematosus: associations and interaction with the interleukin-1alpha-889 C/T polymorphism. (PubMed id 15219382)1, 4 Parks C.G....Cooper G.S. (2004)
    210. Is HLA class II susceptibility to primary antiphospholipid syndrome different from susceptibility to secondary antiphospholipid syndrome? (PubMed id 14995006)1, 4 Freitas M.V....Louzada-Junior P. (2004)
    211. HLA-DRB1* alleles and temporomandibular joint erosion in patients with various rheumatic diseases. (PubMed id 15124939)1, 4 Helenius L.M....Leirisalo-Repo M. (2004)
    212. HLA class II (DRB1, DQA1 and DQB1) allele and haplotype frequencies among HIV-infection discordant Thai couples. (PubMed id 15565951)1, 4 Bejrachandra S....Chandanayingyong D. (2004)
    213. Interaction between RANKL and HLA-DRB1 genotypes may contribute to younger age at onset of seropositive rheumatoid arthritis in an inception cohort. (PubMed id 15476205)1, 4 Wu H....Tsao B.P. (2004)
    214. HLA-DRB1 and -DQB1 alleles and haplotypes in Zambian couples and their associations with heterosexual transmission of HIV type 1. (PubMed id 15116308)1, 4 Tang J....Kaslow R.A. (2004)
    215. Distinct MHC class I and II alleles are associated with hepatitis C viral clearance, originating from a single source. (PubMed id 15239092)1, 4 McKiernan S.M....Kelleher D. (2004)
    216. Bias in parental transmission of the HLA-DR3 allele in Sardinian multiple sclerosis. (PubMed id 15452304)1, 4 Marrosu M.G....Contu P. (2004)
    217. Variation of HLA class II genes in the Nganasan and Ket, two aboriginal Siberian populations. (PubMed id 15009181)1, 4 Uinuk-Ool T.S....Sukernik R.I. (2004)
    218. HLA class II and class I polymorphism in Venezuelan patients with myasthenia gravis. (PubMed id 14700596)1, 4 Fernandez-Mestre M.T....Layrisse Z. (2004)
    219. Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome. (PubMed id 15191952)1, 4 Flomenberg N....Weisdorf D. (2004)
    220. Human leukocyte antigen class II alleles and natural history of HPV 2/27/57-induced common warts. (PubMed id 15257408)1, 4 Spelten B....Rubben A. (2004)
    221. Screening for arthrofibrosis after anterior cruciate ligament reconstruction: analysis of association with human leukocyte antigen. (PubMed id 15122136)1, 4 Skutek M....Bosch U. (2004)
    222. [HLA-Cw alleles polymorphism and haplotypes in Guangdong Han population] (PubMed id 15321756)1, 4 Ma H.J....Ye X. (2004)
    223. HLA-DRB1, TAP2/TAP1, and HLA-DPB1 haplotypes in Finnish juvenile idiopathic arthritis: more complexity within the MHC. (PubMed id 15343265)1, 4 Runstadler J.A....Seldin M.F. (2004)
    224. Specific HLA-DRB and -DQB alleles and haplotypes confer disease susceptibility or resistance in Bahraini type 1 diabetes patients. (PubMed id 15013978)1, 4 Al-Harbi E.M....Almawi W.Y. (2004)
    225. Analysis of HLA DR, HLA DQ, C4A, FcgammaRIIa, FcgammaRIIIa, MBL, and IL-1Ra allelic variants in Caucasian systemic lupus erythematosus patients suggests an effect of the combined FcgammaRIIa R/R and IL-1Ra 2/2 genotypes on disease susceptibility. (PubMed id 15535834)1, 4 Jonsen A....Truedsson L. (2004)
    226. The rising incidence of childhood type 1 diabetes and reduced contribution of high-risk HLA haplotypes. (PubMed id 15530631)1, 4 Gillespie K.M....Gale E.A. (2004)
    227. HLA haplotypes associated with type 1 diabetes mellitus in North Indian children. (PubMed id 14700595)1, 4 Kanga U....Mehra N.K. (2004)
    228. HLA-DR-DQ haplotypes and genotypes in Finnish patients with rheumatoid arthritis. (PubMed id 15479890)1, 4 Laivoranta-Nyman S....Ilonen J. (2004)
    229. Two major histocompatibility complex haplotypes influence susceptibility to sporadic inclusion body myositis: critical evaluation of an association with HLA-DR3. (PubMed id 15496200)1, 4 Price P....Laing N. (2004)
    230. [Analysis of HLA-DRB1,DQB1 allele polymorphism in the Kunming Yi nationality population] (PubMed id 15476187)1, 4 Wen G....Yu L. (2004)
    231. Association of maternal histocompatibility at class II HLA loci with maternal microchimerism in the fetus. (PubMed id 15128924)1, 4 Berry S.M....Kaplan J. (2004)
    232. HLA allele frequency and clinical outcome in Italian patients with cutaneous melanoma. (PubMed id 15191529)1, 4 Luongo V....Lombardi M.L. (2004)
    233. Human leucocyte antigen polymorphisms in nut-allergic patients in South Wales. (PubMed id 15144462)1, 4 Hand S....Davies B.H. (2004)
    234. Chagas' disease susceptibility/resistance: linkage disequilibrium analysis suggests epistasis between major histocompatibility complex and interleukin-10. (PubMed id 15191519)1, 4 Moreno M....Arcos-Burgos M. (2004)
    235. [The distribution of HLA alleles class I and class II among patientes with psoriatic arthritis in Croatia] (PubMed id 15554365)1, 4 Grubic Z....Kerhin-Brkljacic V. (2004)
    236. HLA class-I and class-II allele frequencies and two-locus haplotypes in Melanesians of Vanuatu and New Caledonia. (PubMed id 15546341)1, 4 Maitland K....Williams T.N. (2004)
    237. [Predictive genetic screening for type-1 diabetes in the Hungarian population] (PubMed id 15049049)1, 4 Hermann R. and Soltesz G. (2004)
    238. Development of donor-specific microchimerism in liver transplant recipient with HLA-DRB1 and -DQB1 mismatch related to rejection episodes. (PubMed id 15194331)1, 4 Araujo M.B....Kraemer M.H. (2004)
    239. HLA-DR B1 and DQ B1 polymorphisms in patients with coronary artery ectasia. (PubMed id 15529553)1, 4 Akdemir R....Uyan C. (2004)
    240. Analysis of children with type 1 diabetes in Korea: high prevalence of specific anti-islet autoantibodies, immunogenetic similarities to Western populations with 'unique' haplotypes, and lack of discrimination by aspartic acid at position 57 of DQB. (PubMed id 15507397)1, 4 Yu J....Eisenbarth G.S. (2004)
    241. Differences in the contribution of HLA-DR and -DQ haplotypes to susceptibility to adult- and childhood-onset type 1 diabetes in Japanese patients. (PubMed id 15448101)1, 4 Murao S....Osawa H. (2004)
    242. [Association of HLA-DRB1*1501 polymorphism with the susceptibility to severe chronic periodontitis in Chinese Han nationality] (PubMed id 15269854)1, 4 Zhang S.J....Tang Y. (2004)
    243. A study of HLA-DR and -DQ alleles in 588 patients and 562 controls confirms that HLA-DRB1*03 is associated with recurrent miscarriage. (PubMed id 15070884)1, 4 Kruse C....Christiansen O.B. (2004)
    244. Molecular typing of human leukocyte antigen and related polymorphisms following whole genome amplification. (PubMed id 15304010)1, 4 Shao W....Kaslow R.A. (2004)
    245. Helicobacter pylori infection: CagA-specific antibodies are associated with clinical outcome, but not with HLA-class II polymorphisms of the host. (PubMed id 12635936)1, 4 Kunstmann E....Epplen J.T. (2003)
    246. [Genotyping of HLA-DRB by oligonucleotide arrays in Han populations in southern China] (PubMed id 12820921)1, 4 Xiao J.Q....Ding Y.D. (2003)
    247. HLA types in celiac disease patients not carrying the DQA1*05-DQB1*02 (DQ2) heterodimer: results from the European Genetics Cluster on Celiac Disease. (PubMed id 12651074)1, 4 Karell K....Partanen J. (2003)
    248. Candidate gene studies in focal dystonia. (PubMed id 14581671)1, 4 Sibbing D....Bandmann O. (2003)
    249. Association between human leukocyte antigen polymorphism and human papillomavirus 16-positive vulval intraepithelial neoplasia in British women. (PubMed id 12543794)1, 4 Davidson E.J....Stern P.L. (2003)
    250. The degree of matching at HLA-DPB1 predicts for acute graft-versus-host disease and disease relapse following haematopoietic stem cell transplantation. (PubMed id 12774051)1, 4 Shaw B.E....Madrigal J.A. (2003)
    251. Myelin basic protein gene is associated with MS in DR4- and DR5-positive Italians and Russians. (PubMed id 12939427)1, 4 Guerini F.R....Favorova O.O. (2003)
    252. Association of the HLA-DRB1 gene locus with gastric adenocarcinoma in Japan. (PubMed id 12870731)1, 4 Ohtani M....Kuriyama M. (2003)
    253. Meningioma: is there an association with human leukocyte antigens? (PubMed id 14693734)1, 4 Machulla H.K....Rainov N.G. (2003)
    254. HLA class II is associated with distal interphalangeal osteoarthritis. (PubMed id 12594107)1, 4 Riyazi N....Kloppenburg M. (2003)
    255. Reduced frequency of HLA DRB1*03-DQB1*02 in children with type 1 diabetes associated with enterovirus RNA. (PubMed id 12721936)1, 4 Craig M.E....Rawlinson W.D. (2003)
    256. Ethnic differences in the associations between the HLA-DRB1*04 subtypes and type 1 diabetes. (PubMed id 14679080)1, 4 Rewers A....Erlich H.A. (2003)
    257. [Clinical, metabolic, immunologic and genotypic characteristics in non-pediatric patients with type 1A diabetes mellitus. Onset and short-term prognosis] (PubMed id 12605834)1, 4 Aguilera E....Conget I. (2003)
    258. Heterozygosity or homozygosity for 2 HLA class II haplotypes predict favorable outcomes for renal cell carcinoma treated with cytokine therapy. (PubMed id 12771724)1, 4 Ellerhorst J.A....Grimm E.A. (2003)
    259. The HLA-DRB, -DQB polymorphism and anti-insulin antibody response in Slovenian patients with type 1 diabetes. (PubMed id 12787001)1, 4 Battelino T....Vidan-Jeras B. (2003)
    260. [HLA-DRB and -DQB allele contribution to narcolepsy susceptibility in Chinese patients with narcolepsy] (PubMed id 12887819)1, 4 Han F....Ding D.J. (2003)
    261. New HLA haplotype frequency reference standards: high-resolution and large sample typing of HLA DR-DQ haplotypes in a sample of European Americans. (PubMed id 12974796)1, 4 Klitz W....Fernandez-Vina M. (2003)
    262. HLA genotypes and disease severity assessed by magnetic resonance imaging findings in patients with multiple sclerosis. (PubMed id 14504973)1, 4 Zivadinov R....Zorzon M. (2003)
    263. Association between HLA class II gene and susceptibility or resistance to chronic hepatitis B. (PubMed id 14562382)1, 4 Jiang Y.G....Liu J. (2003)
    264. Genetic background of Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis: association of HLA-DRB1*0901 with microscopic polyangiitis. (PubMed id 12858454)1, 4 Tsuchiya N....Hashimoto H. (2003)
    265. Association of the CTLA-4 gene 49 A/G polymorphism with type 1 diabetes and autoimmune thyroid disease in Japanese children. (PubMed id 12610047)1, 4 Mochizuki M....Nanazawa S. (2003)
    266. Are there HLA combinations typical supporting for or making resistant against aggressive and/or chronic periodontitis? (PubMed id 12941076)1, 4 Stein J....Machulla H.K. (2003)
    267. Dissecting the associations of endemic pemphigus foliaceus (Fogo Selvagem) with HLA-DRB1 alleles and genotypes. (PubMed id 12618858)1, 4 Pavoni D.P....Petzl-Erler M.L. (2003)
    268. HLA-DRB1*, -DQB1* in Piramalai Kallars and Yadhavas, two Dravidian-speaking castes of Tamil Nadu, South India. (PubMed id 12823769)1, 4 Shanmugalakshmi S....Pitchappan R.M. (2003)
    269. HLA-A, B, C, DRB1, DQB1 matching heterogeneity in 'favourably matched' kidney recipients. (PubMed id 14551034)1, 4 Rees M.T. and Darke C. (2003)
    270. Common genomic HLA haplotypes contributing to successful donor search in unrelated hematopoietic transplantation. (PubMed id 12665835)1, 4 Pedron B....Sterkers G. (2003)
    271. HLA in Czech adult patients with autoimmune diabetes mellitus: comparison with Czech children with type 1 diabetes and patients with type 2 diabetes. (PubMed id 14675393)1, 4 Cerna M....Andel M. (2003)
    272. HLA class II associations with rheumatic heart disease among clinically homogeneous patients in children in Latvia. (PubMed id 14680508)1, 4 Stanevicha V....Shantere R. (2003)
    273. HLA-DRB1*1101: a significant risk factor for sarcoidosis in blacks and whites. (PubMed id 14508706)1, 4 Rossman M.D....Monos D. (2003)
    274. Polymorphism of HLA-DMA and DMB alleles in patients with systemic lupus erythematosus. (PubMed id 12858445)1, 4 Morel J....Eliaou J.F. (2003)
    275. Evidence for novel DRB1*15 allele association among clinically definite multiple sclerosis patients from Mumbai, India. (PubMed id 12651075)1, 4 Kankonkar S....Shankarkumar U. (2003)
    276. HLA-DQA1*0301-associated susceptibility for autoimmune polyglandular syndrome type II and III. (PubMed id 12734793)1, 4 Wallaschofski H....Lohmann T. (2003)
    277. Association of MICA polymorphism with rheumatoid arthritis patients in Koreans. (PubMed id 14630402)1, 4 Mok J.W....Park K.S. (2003)
    278. Limited diversity of HLA-DRB1*02 alleles and DRB1-DRB5 haplotype associations in four United States population groups. (PubMed id 12694574)1, 4 Baldassarre L.A....Hurley C.K. (2003)
    279. Pemphigus vulgaris in Jewish patients is associated with HLA-A region genes: mapping by microsatellite markers. (PubMed id 12878355)1, 4 Slomov E....Gazit E. (2003)
    280. The role of HLA-DRB1*04 alleles and their association with HLA-DQB genes in genetic susceptibility to rheumatoid arthritis in Hungarian patients. (PubMed id 12793199)1, 4 Varga E....Petri I.B. (2003)
    281. Two subtypes of hepatitis B virus-associated glomerulonephritis are associated with different HLA-DR2 alleles in Koreans. (PubMed id 14617034)1, 4 Park M.H....Lee H.S. (2003)
    282. Study of host and virological factors of patients with chronic HCV infection and associated laboratory or clinical autoimmune manifestations. (PubMed id 14740435)1, 4 Vassilopoulos D....Calabrese L.H. (2003)
    283. Long-term follow-up of hepatitis C virus infection: H LA class II loci influences the natural history of the disease. (PubMed id 12694584)1, 4 Yoshizawa K....Kiyosawa K. (2003)
    284. [Effects of HCV genotypes and HLA-DRB alleles on the response of chronic hepatitis C patients to interferon alpha and libavilin] (PubMed id 14572343)1, 4 Jiao J. and Wang J.B. (2003)
    285. Protective effect of DRB1 locus against type 2 diabetes mellitus in Mexican Mestizos. (PubMed id 12507821)1, 4 Perez-Luque E....Gorodezky C. (2003)
    286. Genetic and functional studies in multiple sclerosis patients from Martinique attest for a specific and direct role of the HLA-DR locus in the syndrome. (PubMed id 12694585)1, 4 Quelvennec E....Semana G. (2003)
    287. Association of the TAP2*Bky2 allele with presence of SS-A/Ro and other autoantibodies in Japanese patients with systemic lupus erythematosus. (PubMed id 12729048)1, 4 Kanagawa S....Kumagai S. (2003)
    288. Analysis of HLA class I and II alleles in sporadic inclusion-body myositis. (PubMed id 14648147)1, 4 Lampe J.B....Lochmuller H. (2003)
    289. Comparison of TAP2 frequencies in type 1 diabetes patients and healthy controls from three ethnic groups indicates an African origin for the TAP2 G allele. (PubMed id 12786999)1, 4 Hoarau J.J....Pabion M. (2003)
    290. The complexity of HLA class II (DRB1, DQB1, DM) associations with disseminated Mycobacterium avium complex infection among HIV-1-seropositive whites. (PubMed id 12794545)1, 4 Naik E....Kaslow R.A. (2003)
    291. [Genetic history of Aleuts of the Komandor islands from results of analyzing variability of class II HLA genes] (PubMed id 14964841)1, 4 Volod'ko N.V....Sukernik R.I. (2003)
    292. Frequency of HLA class 1 and 2 alleles in Brazilian patients with AIDS and cytomegalovirus retinitis. (PubMed id 14510801)1, 4 Veronese Rodrigues M.d.e. . . . . . . . . . . .L....Donadi E.A. (2003)
    293. Variation in immune response genes and chronic Q fever. Concepts: preliminary test with post-Q fever fatigue syndrome. (PubMed id 12595908)1, 4 Helbig K.J....Marmion B.P. (2003)
    294. HLA alleles in isolated populations from North Spain: origin of the Basques and the ancient Iberians. (PubMed id 12753657)1, 4 Sanchez-Velasco P....Arnaiz-Villena A. (2003)
    295. Human leukocyte antigen class II genes and Helicobacter pylori infection: does genotype overwhelm environmental exposure? (PubMed id 12921878)1, 4 Russo A....Bertario L. (2003)
    296. Temporal changes in the frequencies of HLA genotypes in patients with Type 1 diabetes--indication of an increased environmental pressure? (PubMed id 12687342)1, 4 Hermann R....Ilonen J. (2003)
    297. HLA class II genotypic frequencies in atopic asthma: association of DRB1*01-DQB1*0501 genotype with Artemisia vulgaris allergic asthma. (PubMed id 12878360)1, 4 Torio A....Alvarez-Lopez M.R. (2003)
    298. Human leukocyte antigen class I and II alleles and response to interferon-alpha treatment, in Taiwanese patients with chronic hepatitis C virus infection. (PubMed id 12825172)1, 4 Yu M.L....Chang W.Y. (2003)
    299. HLA class II allele frequencies in the Lebanese population. (PubMed id 12835080)1, 4 Samaha H....Hakime N. (2003)
    300. HLA class II antigens associated with lupus nephritis in Italian SLE patients. (PubMed id 12651073)1, 4 Marchini M....Scorza R. (2003)
    301. A population- and family-based study of Canadian families reveals association of HLA DRB1*0103 with colonic involvement in inflammatory bowel disease. (PubMed id 12656131)1, 4 Silverberg M.S....Siminovitch K.A. (2003)
    302. HLA class II alleles in systemic sclerosis patients with anti-RNA polymerase I/III antibody: associations with subunit reactivities. (PubMed id 14677183)1, 4 Kuwana M....Kaburaki J. (2003)
    303. HLA-DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South-western China. (PubMed id 12694588)1, 4 Fu Y....Xu A. (2003)
    304. Independent association of HLA-DR and FCgamma receptor polymorphisms in Korean patients with systemic lupus erythematosus. (PubMed id 12867584)1, 4 Lee H.S....Yoo D.H. (2003)
    305. MCP-1 promoter polymorphism in Spanish patients with rheumatoid arthritis. (PubMed id 12826377)1, 4 Gonzalez-Escribano M.F....Nunez-Roldan A. (2003)
    306. Roles of HLA-B, HLA-C and HLA-DPA1 incompatibilities in the outcome of unrelated stem-cell transplantation. (PubMed id 12956878)1, 4 Schaffer M....Olerup O. (2003)
    307. Immunogenetics of the rare HLA-B allele B*4408. (PubMed id 12648281)1, 4 Street J....Darke C. (2003)
    308. Genetic affinities among Mongol ethnic groups and their relationship to Turks. (PubMed id 12753667)1, 4 Machulla H.K....Dorak M.T. (2003)
    309. MHC class II alleles in Mexican patients with rheumatic heart disease. (PubMed id 14602216)1, 4 Hernandez-Pacheco G....Vargas-Alarcon G. (2003)
    310. Associations of MHC ancestral haplotypes with resistance/susceptibility to AIDS disease development. (PubMed id 12574360)1, 4 Flores-Villanueva P.O....Zagury J.F. (2003)
    311. Evidence for human leukocyte antigen-related susceptibility in idiopathic childhood ischemic stroke. (PubMed id 12373032)1, 4 Zou L.P....Mix E. (2002)
    312. [Comparative study of HLA-DQA1 and HLA-DRB1 allele in patients with endometriosis and adenomyosis] (PubMed id 11836687)1, 4 Zong L....Xu A. (2002)
    313. Differences in idiopathic inflammatory myopathy phenotypes and genotypes between Mesoamerican Mestizos and North American Caucasians: ethnogeographic influences in the genetics and clinical expression of myositis. (PubMed id 12124873)1, 4 Shamim E.A....Miller F.W. (2002)
    314. HLA class II markers and clinical heterogeneity in Swedish patients with primary biliary cirrhosis. (PubMed id 12144621)1, 4 Wassmuth R....Lindgren S. (2002)
    315. Class II MHC alleles in rheumatoid arthritis in Tamilnadu, India: is there an association? (PubMed id 12021152)1, 4 Parthiban M....Chandrasekaran A.N. (2002)
    316. Newborn screening for high-risk human leukocyte antigen markers associated with insulin-dependent diabetes mellitus: the ABIS study. (PubMed id 12021131)1, 4 Berzina L....Sanjeevi C.B. (2002)
    317. Nodular disease in rheumatoid arthritis: association with cigarette smoking and HLA-DRB1/TNF gene interaction. (PubMed id 12415586)1, 4 Mattey D.L....Ollier W.E. (2002)
    318. A null mutation within the ciliary neurotrophic factor (CNTF)-gene: implications for susceptibility and disease severity in patients with multiple sclerosis. (PubMed id 11857064)1, 4 Hoffmann V....Hardt C. (2002)
    319. Association between two tumour necrosis factor intronic polymorphisms and HLA alleles. (PubMed id 11841486)1, 4 Low A.S....Wilson A.G. (2002)
    320. HLA profile of three ethnic groups living in the North-Western region of Russia. (PubMed id 11972877)1, 4 Evseeva I....Alexeev L.L. (2002)
    321. [Association of immune response to hepatitis B vaccine with HLA-DRB1*02, 07, 09 genes in the population of Han nationality in Guangdong Province] (PubMed id 12390851)1, 4 Qian Y....Luo K.X. (2002)
    322. Association of CTLA-4 with systemic sclerosis in Japanese patients. (PubMed id 12508774)1, 4 Takeuchi F....Tanimoto K. (2002)
    323. Additional association of intra-MHC genes, MICA and D6S273, with Addison's disease. (PubMed id 12392510)1, 4 Park Y.S....Eisenbarth G.S. (2002)
    324. Stromelysin 1 (matrix metalloproteinase 3) and HLA-DRB1 gene polymorphisms: Association with severity and progression of rheumatoid arthritis in a prospective study. (PubMed id 12124858)1, 4 Constantin A....Cantagrel A. (2002)
    325. Distinctive KIR and HLA diversity in a panel of north Indian Hindus. (PubMed id 11904677)1, 4 Rajalingam R....Parham P. (2002)
    326. Investigation of linkage and association/linkage disequilibrium of HLA A-, DQA1-, DQB1-, and DRB1-alleles in 69 sib-pair- and 89 trio-families with schizophrenia. (PubMed id 11920855)1, 4 Schwab S.G....Wildenauer D.B. (2002)
    327. Association and linkage of juvenile MS with HLA-DR2(15) in Russians. (PubMed id 11865153)1, 4 Boiko A.N....Favorova O.O. (2002)
    328. HLA DRB10405-DQB10401 haplotype is associated with autoimmune pancreatitis in the Japanese population. (PubMed id 11984513)1, 4 Kawa S....Kiyosawa K. (2002)
    329. Susceptibility locus for non-obstructive azoospermia is localized within the HLA-DR/DQ subregion: primary role of DQB1*0604. (PubMed id 12366783)1, 4 Matsuzaka Y....Inoko H. (2002)
    330. Association of HLA-DQB1*0301 and HLA-DQB1*0602 with different subtypes of gastric cancer in Taiwan. (PubMed id 11985790)1, 4 Wu M.S....Lin J.T. (2002)
    331. TAP, HLA-DQB1, and HLA-DRB1 polymorphism in Colombian patients with primary Sjogren's syndrome. (PubMed id 12077712)1, 4 Anaya J.M....Arcos-Burgos M. (2002)
    332. [Determination of HLA-DRB1 gene polymorphism by PCR-SBT in Lahu ethnic group of Yunnan, China] (PubMed id 16118124)1, 4 Jia Z.J....Xu A.L. (2002)
    333. MICA rather than MICB, TNFA, or HLA-DRB1 is associated with susceptibility to psoriatic arthritis. (PubMed id 12022360)1, 4 Gonzalez S....Lopez-Larrea C. (2002)
    334. HLA-DRB1*1502 confers susceptibility to ulcerative colitis, but is negatively associated with its intractability: a Korean study. (PubMed id 12073071)1, 4 Myung S.J....Min I. (2002)
    335. Susceptibility to primary sclerosing cholangitis in Brazil is associated with HLA-DRB1*13 but not with tumour necrosis factor alpha -308 promoter polymorphism. (PubMed id 12235090)1, 4 Bittencourt P.L....Goldberg A.C. (2002)
    336. Association of HLA class I and class II alleles with susceptibility to endometriosis. (PubMed id 12392856)1, 4 Kitawaki J....Honjo H. (2002)
    337. TAP1 and TAP2 gene polymorphism in rheumatoid arthritis in a population in eastern France. (PubMed id 12047361)1, 4 Zhang S.L....Toussirot E. (2002)
    338. Evaluation of the role of MHC class II alleles, haplotypes and selected amino acid sequences in primary sclerosing cholangitis. (PubMed id 12765483)1, 4 Donaldson P.T. and Norris S. (2002)
    339. HLA-DRB1, DQB1, and DQA1 allele profile in Brazilian patients with type 1 diabetes mellitus. (PubMed id 12021129)1, 4 Fernandes A.P....Donadi E.A. (2002)
    340. DR3 is associated with type 1 diabetes and blood group ABO incompatibility. (PubMed id 12021139)1, 4 Berzina L....Sanjeevi C.B. (2002)
    341. Juvenile idiopathic arthritis classified by the ILAR criteria: HLA associations in UK patients. (PubMed id 12364641)1, 4 Thomson W....Southwood T. (2002)
    342. Pediatric celiac disease in India is associated with multiple DR3-DQ2 haplotypes. (PubMed id 12121676)1, 4 Kaur G....Mehra N.K. (2002)
    343. Mannose-binding lectin variant alleles and HLA-DR4 alleles are associated with giant cell arteritis. (PubMed id 12375325)1, 4 Jacobsen S....Garred P. (2002)
    344. HLA class II alleles and haplotypes in Icelandic Type I diabetic patients: comparison of Icelandic and Norwegian populations. (PubMed id 11914753)1, 4 Backman V.M....Stefansson K. (2002)
    345. The first large population based twin study of coeliac disease. (PubMed id 11950806)1, 4 Greco L....Stazi M.A. (2002)
    346. HLA and cytokine gene polymorphisms in biliary atresia. (PubMed id 12100571)1, 4 Donaldson P.T....Kelley D. (2002)
    347. Genotyping for HLA-A, B and C alleles in Japanese patients with pemphigus: prevalence of Asian alleles of the HLA-B15 family. (PubMed id 11841366)1, 4 Miyagawa S....Kaneshige T. (2002)
    348. HLA class II alleles in patients with alopecia areata. (PubMed id 11978563)1, 4 Akar A....Gur A.R. (2002)
    349. DRB1*14 diversity and DRB3 associations in four major population groups in the United States. (PubMed id 12144619)1, 4 Gans C.P.... Hurley C.K. (2002)
    350. HLA-DR/DQ haplotype in rheumatoid arthritis: novel allelic associations in UK Caucasians. (PubMed id 12233873)1, 4 Milicic A....Wordsworth B.P. (2002)
    351. Histological features and HLA class II alleles in hepatitis C virus chronically infected patients with persistently normal alanine aminotransferase levels. (PubMed id 12235085)1, 4 Renou C....Caillat-Zucman S. (2002)
    352. HLA-DQ8 and the HLA-DQ8-DR4 haplotype are positively associated with the hevein-specific IgE immune response in health care workers with latex allergy. (PubMed id 12209103)1, 4 Rihs H.P....Bruning T. (2002)
    353. HLA polymorphism in a Majorcan population of Jewish descent: comparison with Majorca, Minorca, Ibiza (Balearic Islands) and other Jewish communities. (PubMed id 12472657)1, 4 Crespi C....Matamoros N. (2002)
    354. HLA class II DNA typing in a large series of European patients with systemic lupus erythematosus: correlations with clinical and autoantibody subsets. (PubMed id 11997714)1, 4 Galeazzi M....Marcolongo R. (2002)
    355. DRB1*1502-DQB1*0601-DQA1*0103 and DRB1*04-DQB1*0302 in Jewish hypersomnolent patients. (PubMed id 14592217)1, 4 Peled N....Pillar G. (2002)
    356. Asian-specific HLA haplotypes reveal heterogeneity of the contribution of HLA-DR and -DQ haplotypes to susceptibility to type 1 diabetes. (PubMed id 11812768)1, 4 Kawabata Y....Ogihara T. (2002)
    357. HLA-DRB1 and DQB1 allele distribution in the Muong population exposed to malaria in Vietnam. (PubMed id 12445316)1, 4 Busson M....Hors J. (2002)
    358. Positive association between HLA-DRB1*07 and specific IgE responses to purified major allergens of D. pteronyssinus (Der p 1 and Der p 2). (PubMed id 11868921)1, 4 Kim Y.K....Min K.U. (2002)
    359. Molecular genetic analysis of HLA-DR and -DQ alleles in Spanish patients with melanoma. (PubMed id 12125959)1, 4 Nagore E....Fortea J.M. (2002)
    360. HLA haplotypes and susceptibility to rheumatoid arthritis. More than class II genes. (PubMed id 12455817)1, 4 Pascual M....Martin J. (2002)
    361. [Genotyping of HLA-DRB1 by PCR-SSP in Yunnan Lahu ethnic groups] (PubMed id 12905660)1, 4 Hong K.X....Chu J.Y. (2002)
    362. HLA-DRB alleles and systemic lupus erythematosus in Jamaicans. (PubMed id 12144077)1, 4 Smikle M....Nicholson G. (2002)
    363. Differences in the genetic background of latent autoimmune diabetes in adults (LADA) and type 1 diabetes mellitus. (PubMed id 12270547)1, 4 Vatay A....Panczel P. (2002)
    364. Studies on the association of Fc gamma receptor IIA, IIB, IIIA and IIIB polymorphisms with rheumatoid arthritis in the Japanese: evidence for a genetic interaction between HLA-DRB1 and FCGR3A. (PubMed id 12486608)1, 4 Kyogoku C....Tokunaga K. (2002)
    365. The clinical significance of human leukocyte antigen (HLA) allele compatibility in patients receiving a marrow transplant from serologically HLA-A, HLA-B, and HLA-DR matched unrelated donors. (PubMed id 12010826)1, 4 Morishima Y....Kodera Y. (2002)
    366. Preeclampsia: a multifactorial disease resulting from the interaction of the feto-maternal HLA genotype and HCMV infection. (PubMed id 12443029)1, 4 Carreiras M....Layrisse Z. (2002)
    367. Heterogeneity of HLA-DRB1*04 and its associated haplotypes in the North Indian population. (PubMed id 11916167)1, 4 Jaini R....Mehra N.K. (2002)
    368. Human leukocyte antigen class II and cervical cancer risk: a population-based study. (PubMed id 12447731)1, 4 Madeleine M.M....Galloway D.A. (2002)
    369. Infectious complications in sickle cell disease are influenced by HLA class II alleles. (PubMed id 11872237)1, 4 Tamouza R....Charron D. (2002)
    370. [The relationship between silicosis and the polymorphism of HLA-DRB1 *, DQB1 * genes] (PubMed id 14694619)1, 4 Yuan B....Shan X. (2002)
    371. Polymorphisms of the human leukocyte antigen DRB1 and DQB1 genes and the natural history of human papillomavirus infection. (PubMed id 12134251)1, 4 Maciag P.C....Villa L.L. (2002)
    372. A male-specific increase in the HLA-DRB4 (DR53) frequency in high-risk and relapsed childhood ALL. (PubMed id 12008082)1, 4 Dorak M.T....Carin M. (2002)
    373. HLA class II sequence-based typing in normal Saudi individuals. (PubMed id 12445309)1, 4 Al-Hussein K.A....Tilanus M.G. (2002)
    374. Association of HLA-DRB1*1502-DQB1*0501 haplotype with susceptibility to systemic lupus erythematosus in Thais. (PubMed id 12028537)1, 4 Sirikong M....Tokunaga K. (2002)
    375. Genetic dissection of the human leukocyte antigen region by use of haplotypes of Tasmanians with multiple sclerosis. (PubMed id 11923913)1, 4 Rubio J.P....Foote S.J. (2002)
    376. Role of G protein beta3 subunit C825T and HLA class II polymorphisms in the immune response after HBV vaccination. (PubMed id 12083823)1, 4 Lindemann M....Grosse-Wilde H. (2002)
    377. The association of specific HLA class I and II alleles with type 1 diabetes among Filipinos. (PubMed id 12445315)1, 4 Bugawan T.L....Erlich H.A. (2002)
    378. Origin and affinities of indigenous Siberian populations as revealed by HLA class II gene frequencies. (PubMed id 11935333)1, 4 Uinuk-Ool T.S....Klein J. (2002)
    379. A comparison of HLA-DR and -DQ allele and haplotype frequencies in Trinidadian populations of African, South Asian, and mixed ancestry. (PubMed id 12392858)1, 4 Carrington C.V....Stephens H.A. (2002)
    380. Human leukocyte antigen class II alleles may contribute to the severity of hepatitis C virus-related liver disease. (PubMed id 12089669)1, 4 Hue S....Caillat-Zucman S. (2002)
    381. CTLA-4 gene polymorphism contributes to the genetic risk for latent autoimmune diabetes in adults. (PubMed id 12021137)1, 4 Cosentino A....Falorni A. (2002)
    382. HLA-DR and DQ polymorphisms in bullous pemphigoid from northern China. (PubMed id 12139680)1, 4 Gao X.H....Wojnarowska F. (2002)
    383. HLA-patterns in patients with multiple sclerosis and type I diabetes mellitus: evidence for possible mutual exclusion of both diseases. (PubMed id 12149602)1, 4 Lobnig B.M....Tuomilehto-Wolf E. (2002)
    384. Analysis of HLA in children with gelatin allergy. (PubMed id 12144625)1, 4 Sakaguchi M....Inouye S. (2002)
    385. HLA class II haplotypic association and DQCAR microsatellite polymorphisms in Croatian patients with psoriasis. (PubMed id 12137324)1, 4 Grubic Z....Kastelan A. (2002)
    386. HLA haplotypes and class II molecular alleles in Argentinian patients with pemphigus vulgaris. (PubMed id 12196893)1, 4 Glorio R....Woscoff A. (2002)
    387. Associations of HLA class II alleles with pulmonary tuberculosis in Thais. (PubMed id 12358854)1, 4 Vejbaesya S....Stephens H.A. (2002)
    388. Common HLA-B8-DR3 haplotype in Northern India is different from that found in Europe. (PubMed id 12542740)1, 4 Witt C.S....Mehra N.K. (2002)
    389. Association of HLA-DQ and HLA-DR alleles with susceptibility or resistance to HIV-1 infection among the population of Chaco Province, Argentina. (PubMed id 12150008)1, 4 Motta P....Habegger de Sorrentino A. (2002)
    390. [Frequency of DRB1* and DQB1* alleles in Polish patients with dilated cardiomyopathy] (PubMed id 12362498)1, 4 Bilinska Z.T....Ruzyl/l/o W. (2002)
    391. HLA and hypocretin studies in Korean patients with narcolepsy. (PubMed id 12071546)1, 4 Hong S.C....Mignot E. (2002)
    392. CTLA-4 49 A/G dimorphism and type 1 diabetes susceptibility: a French case-control study and segregation analysis. Evidence of a maternal effect. (PubMed id 12047362)1, 4 Fajardy I....Fontaine P. (2002)
    393. HLA class II haplotypes associated with pulmonary interstitial lesions of polymyositis/dermatomyositis in Japanese patients. (PubMed id 11972875)1, 4 Horiki T....Inoko H. (2002)
    394. HLA-DQBl alleles and susceptibility to cervical squamous cell carcinoma in Southern Iranian patients. (PubMed id 11994765)1, 4 Dehaghani A.S....Ghaderi A. (2002)
    395. DRB1*03 diversity and DRB3 associations in five major population groups in the United States. (PubMed id 11872240)1, 4 Tang T.F....Katovich Hurley C. (2002)
    396. Human leukocyte antigen alleles in patients with bipolar disorder in the Korean population. (PubMed id 12109964)1, 4 Jun T.Y....Han H. (2002)
    397. HLA-A, B, Cw, DRB1, DRB3/4/5, DQB1 in German patients suffering from rapidly progressive periodontitis (RPP) and adult periodontitis (AP). (PubMed id 12296785)1, 4 Machulla H.K....Reichert S. (2002)
    398. MHC class I chain related gene A (MICA) modulates the development of coeliac disease in patients with the high risk heterodimer DQA1*0501/DQB1*0201. (PubMed id 11839711)1, 4 Lopez-Vazquez A....Lopez-Larrea C. (2002)
    399. Crohn disease: susceptibility and disease heterogeneity revealed by HLA genotyping. (PubMed id 11423176)1, 4 Lombardi M.L....Castiglione F. (2001)
    400. Associations of MHC class II alleles in Norwegian primary Sjogren's syndrome patients: implications for development of autoantibodies to the Ro52 autoantigen. (PubMed id 11555411)1, 4 Nakken B....Halse A.K. (2001)
    401. Immunogenetics of HLA class II in Israeli Ashkenazi Jewish, Israeli non-Ashkenazi Jewish, and in Israeli Arab IDDM patients. (PubMed id 11165718)1, 4 Kwon O.J....Israel S. (2001)
    402. HLA class II gene polymorphisms in antiphospholipid syndrome: haplotype analysis in 83 Caucasoid patients. (PubMed id 11157139)1, 4 Caliz R....Hughes G.R. (2001)
    403. Association of HLA-DR genotypes and IL-1ra gene polymorphism with treatment failure of budesonide and disease patterns in Crohn's disease. (PubMed id 11742191)1, 4 Gelbmann C.M....Andus T. (2001)
    404. Case-control study with narcoleptic patients and healthy controls who, like the patients, possess both HLA-DRB1*1501 and -DQB1*0602. (PubMed id 11285131)1, 4 Hohjoh H....Tokunaga K. (2001)
    405. Human leukocyte antigen class II allele frequencies and haplotype association in Iranian normal population. (PubMed id 11704285)1, 4 Amirzargar A....Ghaderi A. (2001)
    406. HLA polymorphism in the Murcia population (Spain): in the cradle of the archaeologic Iberians. (PubMed id 11543893)1, 4 Muro M....Alvarez-Lopez M.R. (2001)
    407. Polymorphism of Immune Response Genes as a Factor for Predisposition to Development of Diseases. (PubMed id 12687213)1, 4 Konenkov V.I....Smolnikova M.V. (2001)
    408. Human leukocyte antigen class I and II alleles and risk of cervical neoplasia: results from a population-based study in Costa Rica. (PubMed id 11679920)1, 4 Wang S.S....Apple R.J. (2001)
    409. Heat-shock protein 70-1 and HLA class II gene polymorphisms associated with celiac disease susceptibility in Navarra (Spain). (PubMed id 11476906)1, 4 Ramos-Arroyo M.A....Valiente A. (2001)
    410. Relationship between HLA-DRB1 and DQ alleles and the genetic susceptibility to type 1 diabetes. (PubMed id 11780465)1, 4 Sang Y....Ni G. (2001)
    411. Novel alleles at the lymphotoxin alpha (LTalpha) locus mark extended HLA haplotypes in native Africans. (PubMed id 11250044)1, 4 Tang J....Kaslow R.A. (2001)
    412. Genes of the class II and class III major histocompatibility complex are associated with typhoid fever in Vietnam. (PubMed id 11120931)1, 4 Dunstan S.J....Dougan G. (2001)
    413. HLA alleles in relation to specific immunity to liver stage antigen-1 from plasmodium falciparum in Gabon. (PubMed id 11294566)1, 4 Migot-Nabias F....Deloron P. (2001)
    414. The distribution of HLA class II susceptible/protective haplotypes could partially explain the low incidence of type 1 diabetes in continental Italy (Lazio region). (PubMed id 11929589)1, 4 Petrone A....Buzzetti R. (2001)
    415. HLA class II DR-DQ and increased risk of cervical cancer among Senegalese women. (PubMed id 11588129)1, 4 Lin P....Kiviat N.B. (2001)
    416. [Linkage of allergic rhinitis with HLA-DRB alleles polymorphism] (PubMed id 12541760)1, 4 Xing Z. and Yu D. (2001)
    417. Cytotoxic T lymphocyte antigen 4 gene polymorphism confers susceptibility to type 1 diabetes in Japanese children: analysis of association with HLA genotypes and autoantibodies. (PubMed id 11894970)1, 4 Kikuoka N....Murata M. (2001)
    418. Rheumatoid arthritis in southern Spain: toward elucidation of a unifying role of the HLA class II region in disease predisposition. (PubMed id 11229460)1, 4 Pascual M....Zanelli E. (2001)
    419. HLA class II polymorphism in Aka Pygmies and Bantu Congolese and a reassessment of HLA-DRB1 African diversity. (PubMed id 11782272)1, 4 Renquin J....Kaplan C. (2001)
    420. HLA DMA and DMB show no association with rheumatoid arthritis in US Caucasians. (PubMed id 11881821)1, 4 Moxley G. and Han J. (2001)
    421. Low frequency of HLA DRB1*03 - DQB1*02 and DQB1*0302 haplotypes in Romania is consistent with the country's low incidence of Type I diabetes. (PubMed id 11724419)1, 4 Ionescu-Tirgoviste C....Todd J.A. (2001)
    422. Protection against severe disease is conferred by DERAA-bearing HLA-DRB1 alleles among HLA-DQ3 and HLA-DQ5 positive rheumatoid arthritis patients. (PubMed id 11334677)1, 4 Seidl C....Kaltwasser J.P. (2001)
    423. [Prediction of insulin-dependent diabetes mellitus in children of first-degree relatives of diabetic patients] (PubMed id 11678027)1, 4 Cinek O....Vavrinec J. (2001)
    424. Histocompatibility leucocyte antigens and closely linked immunomodulatory genes in autoimmune thyroid disease. (PubMed id 11678832)1, 4 Hunt P.J....Welsh K.I. (2001)
    425. The HLA class I and class II allele frequencies studied at the DNA level in the Svanetian population (Upper Caucasus) and their relationships to Western European populations. (PubMed id 11782273)1, 4 Sanchez-Velasco P. and Leyva-Cobian F. (2001)
    426. [Analysis of the association between HLA-DRB(1), DQB(1) gene and pulmonary tuberculosis complicated with diabetes mellitus] (PubMed id 11802942)1, 4 Zhao Y....Song C. (2001)
    427. [Association of HLA-DRB1 genes with pulmonary tuberculosis] (PubMed id 11802982)1, 4 Wang J....Wang S. (2001)
    428. HLA and interleukin 1 gene polymorphisms in primary biliary cirrhosis: associations with disease progression and disease susceptibility. (PubMed id 11171832)1, 4 Donaldson P....Jones D. (2001)
    429. Tumour necrosis factor microsatellites and HLA-DRB1*, HLA-DQA1*, and HLA-DQB1* alleles in Peruvian patients with rheumatoid arthritis. (PubMed id 11454644)1, 4 Castro F....Sandberg-Wollheim M. (2001)
    430. Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups. (PubMed id 11179016)1, 4 Mignot E....Risch N. (2001)
    431. HLA-DRB1*07 may have a susceptibility and DRB1*04 a protective effect upon the development of a sensitization to house dust mite Dermatophagoides pteronyssinus. (PubMed id 11167958)1, 4 Kim Y.K....Min K.U. (2001)
    432. Association of chronic lymphocytic leukemia with specific alleles of the HLA-DR4:DR53:DQ8 haplotype in German patients. (PubMed id 11291046)1, 4 Machulla H.K....Langner J. (2001)
    433. HLA class I and class II are both associated with the genetic predisposition to primary Sjogren syndrome. (PubMed id 11423179)1, 4 Loiseau P....Goldberg D. (2001)
    434. Polymorphism and distribution of HLA-DR2 alleles in Mexican populations. (PubMed id 11250046)1, 4 Vargas-Alarcon G....Arnaiz-Villena A. (2001)
    435. Plasma tumor necrosis factor alpha levels and the -238*A promoter polymorphism in patients with antiphospholipid syndrome. (PubMed id 11246532)1, 4 Bertolaccini M.L....Hughes G.R. (2001)
    436. HLA haplotype analysis in Finnish patients with rheumatoid arthritis. (PubMed id 11229461)1, 4 Tuokko J....Ilonen J. (2001)
    437. Six microsatellite markers on the short arm of chromosome 6 in relation to HLA-DR3 and TNF-308A in systemic lupus erythematosus. (PubMed id 11704803)1, 4 van der Linden M.W....Huizinga T.W. (2001)
    438. HLA-DRB3*0101 is associated with Graves' disease in Jamaicans. (PubMed id 11895223)1, 4 Smikie M.F....James O. (2001)
    439. Identification of an association between HLA class II alleles and low antibody levels after measles immunization. (PubMed id 11672906)1, 4 Poland G.A....Schaid D.J. (2001)
    440. HLA class II genes determine the natural variance of hepatitis C viral load. (PubMed id 11124840)1, 4 Fanning L.J....Shanahan F. (2001)
    441. DQA1 and DQB1 promoter diversity and linkage disequilibrium with class II haplotypes in Mexican Mestizo population. (PubMed id 11477477)1, 4 Alaez C....Gorodezky C. (2001)
    442. Analysis of HLA haplotypes in autoimmune hepatitis type 1: identifying the major susceptibility locus. (PubMed id 11182227)1, 4 Goldberg A.C....Kalil J. (2001)
    443. Association of HLA class II genes with systemic sclerosis in Koreans. (PubMed id 11469465)1, 4 Kang S.H....Takeuchi F. (2001)
    444. Class II HLA associations with autoantibodies in scleroderma: a highly significant role for HLA-DP. (PubMed id 11393660)1, 4 Gilchrist F.C....du Bois R.M. (2001)
    445. Evidence for a protective role of the human leukocyte antigen class II region in early rheumatoid arthritis. (PubMed id 11257148)1, 4 Vos K....Zanelli E. (2001)
    446. The telomeric part of the HLA region predisposes to rheumatoid arthritis independently of the class II loci. (PubMed id 11165717)1, 4 Zanelli E....Giphart M.J. (2001)
    447. Can MHC class II genes mediate resistance to type 1 diabetes? (PubMed id 11903620)1, 4 Price P....Allcock R.J. (2001)
    448. Class II allele and haplotype frequencies in Mexican systemic lupus erythematosus patients: the relevance of considering homologous chromosomes in determining susceptibility. (PubMed id 11476905)1, 4 Vargas-Alarcon G....Alarcon-Segovia D. (2001)
    449. The HLA-DR3,DQ2 heterozygous genotype is associated with an accelerated progression of primary sclerosing cholangitis. (PubMed id 11495087)1, 4 Boberg K.M....Schrumpf E. (2001)
    450. HLA-DRB1*03, DRB1*11 or DRB1*12 and their respective DRB3 specificities in clinical variants of sarcoidosis. (PubMed id 11169267)1, 4 Bogunia-Kubik K....Lange A. (2001)
    451. Combination of HLA-A and HLA class II alleles controls the susceptibility to rheumatoid arthritis. (PubMed id 11929590)1, 4 Tsuchiya K....Sasazuki T. (2001)
    452. HLA class II allele distribution in the Gypsy community of Andalusia, southern Spain. (PubMed id 11260508)1, 4 Ramal L.M....Lopez-Nevot M.A. (2001)
    453. HLA class II genetic association of type 1 diabetes mellitus in Czech children. (PubMed id 15016191)1, 4 Cinek O....Ronningen K.S. (2001)
    454. [Two loci HLA haplotypes in celiac children. Linkage imbalance and haplotype frequencies. Comparative study with a control population] (PubMed id 11181188)1, 4 Ruiz del Prado M.Y....Lasierra Diaz M.P. (2001)
    455. Additive effect of the HLA-DR15 haplotype on susceptibility to multiple sclerosis. (PubMed id 11424637)1, 4 Rasmussen H.B....Clausen J. (2001)
    456. Two distinct MICA gene markers discriminate major autoimmune diabetes types. (PubMed id 11502807)1, 4 Gambelunghe G....Falorni A. (2001)
    457. HLA-DR and -DQ polymorphism in Cameroon. (PubMed id 11580849)1, 4 Pimtanothai N....Johnson A.H. (2001)
    458. Human leukocyte antigen class II alleles in white Brazilian patients with celiac disease. (PubMed id 11045836)1, 4 Silva E.M....Donadi E.A. (2000)
    459. Screening for the IDDM high-risk genotype. A rapid microtitre plate method using serum as source of DNA. (PubMed id 11098934)1, 4 Cinek O....Ronningen K.S. (2000)
    460. A comparison of molecular HLA-DR and DQ allele profiles forming DR51-, DR52-, and DR53-related haplotypes in five ethnic Thai populations from mainland southeast Asia. (PubMed id 11082517)1, 4 Stephens H.A....Rungruang E. (2000)
    461. The inter-regional distribution of HLA class II haplotypes indicates the suitability of the Sardinian population for case-control association studies in complex diseases. (PubMed id 11115839)1, 4 Lampis R....Cucca F. (2000)
    462. Allele frequencies and haplotypic associations defined by allelic DNA typing at HLA class I and class II loci in the Japanese population. (PubMed id 11169242)1, 4 Saito S....Ota M. (2000)
    463. [Association of HLA-DRB genes with Vogt-Koyanagi-Harada syndrome in a Chinese Han population] (PubMed id 12903490)1, 4 Zhang M....Hu T. (2000)
    464. Non-class II HLA gene associated with type 1 diabetes maps to the 240-kb region near HLA-B. (PubMed id 11118029)1, 4 Nejentsev S....Ilonen J. (2000)
    465. Contribution of HLA class II genes to end stage renal disease in mexican patients with type 2 diabetes mellitus. (PubMed id 11082516)1, 4 Perez-Luque E....Gorodezky C. (2000)
    466. Major histocompatibility complex class II polymorphisms and risk of cervical cancer and human papillomavirus infection in Brazilian women. (PubMed id 11097225)1, 4 Maciag P.C....Petzl-Erler M.L. (2000)
    467. Susceptibility to severe ulcerative colitis is associated with polymorphism in the central MHC gene IKBL. (PubMed id 11113070)1, 4 de la Concha E.G....Diaz-Rubio M. (2000)
    468. Genetic susceptibility to breast cancer: HLA DQB*03032 and HLA DRB1*11 may represent protective alleles. (PubMed id 11027344)1, 4 Chaudhuri S....Pillai S. (2000)
    469. HLA alleles in patients with Guillain-Barre syndrome. (PubMed id 11776098)1, 4 Li H....Wang S. (2000)
    470. HLA-DRB1 and DQB1 polymorphisms in southern France and genetic relationships with other Mediterranean populations. (PubMed id 11053637)1, 4 Gibert M....Boetsch G. (2000)
    471. [A probe for evaluating the role of HLA class II antigens coded with the DRB gene in etiopathogenesis of familial sarcoidosis in Poland using the K-nearest neighbor experimental statistical method] (PubMed id 11320565)1, 4 Goljan A....Zielinski J. (2000)
    472. [Correlative study on HLA-DR2 allelic polymorphism and systemic lupus erythematosus in the Han nationality in Hunan province] (PubMed id 12212234)1, 4 Tian W....Guo S.S. (2000)
    473. HLA class I and class II allele distribution in the Peruvian population. (PubMed id 11169240)1, 4 de Pablo R....Martin J. (2000)
    474. Co-amoxiclav jaundice: clinical and histological features and HLA class II association. (PubMed id 11034591)1, 4 O'Donohue J....Mills P.R. (2000)
    475. The distribution of HLA class II haplotypes reveals that the Sardinian population is genetically differentiated from the other Caucasian populations. (PubMed id 11169241)1, 4 Lampis R....Cucca F. (2000)
    476. Polymorphisms in the SOD2 and HLA-DRB1 genes are associated with nonfamilial idiopathic dilated cardiomyopathy in Japanese. (PubMed id 10425186)1, 4 Hiroi S....Kimura A. (1999)
    477. A novel HLA-DRB1-DR2 allele associated with HLA mistyping. (PubMed id 8436426)1, 2 Rosenlicht J.W.... Frey J. (1993)
    478. Molecular studies of a rare DR2/LD-5a/DQw3 HLA class II haplotype. Multiple genetic mechanisms in the generation of polymorphic HLA class II genes. (PubMed id 3129499)1, 2 Liu C.P.... Wu S.K. (1988)
    479. HLA-DR2 subtypes form an additional supertypic family of DR beta alleles. (PubMed id 2885840)1, 2 Lee B.S.M.... McDevitt H.O. (1987)
    480. cDNA cloning and sequencing reveals that the electrophoretically constant DR beta 2 molecules, as well as the variable DR beta 1 molecules, from HLA-DR2 subtypes have different amino acid sequences including a hypervariable region for a functionally important epitope. (PubMed id 3571980)1, 2 Wu S.K.... Bach F.H. (1987)
    481. Genetic variations of HLA-DRB1 and susceptibility to Kawasaki disease in Taiwanese children. (PubMed id 17207714)1, 9 Huang F.Y....Lee Y.J. (2007)
    482. Pro-inflammatory variants of DRB1 and RAGE genes are associated with susceptibility to pediatric type 1 diabetes: a new hypothesis on the adaptive role of autoimmunity. (PubMed id 17987563)1, 9 Damiani G....Cuccia M. (2007)
    483. [Study on the genic polymorphism of HLA-DRB1 in a population in the north of China] (PubMed id 12903044)1, 9 Li D....Yu Y. (2003)
    484. HLA-DRB1 allele in 35 patients with alveolar echinococcosis in Gansu Province of China. (PubMed id 14570623)1, 9 Li F....Craig P.S. (2003)
    485. The effect of HLA-DRB1 genes, rheumatoid factor, and treatment on radiographic disease progression in rheumatoid arthritis over 6 years. (PubMed id 11093435)1, 9 Rau R....Fenner H. (2000)
    486. Role of HLA-DRB1 and PTPN22 genes in susceptibility to juvenile idiopathic arthritis in Hungarian patients. (PubMed id 19210888)1, 9 PazA!r B....PoA^r G. (2008)
    487. [Gene and haplotype frequencies for the loci HLA-A, B and DRB1 in 11755 north Chinese Han bone marrow registry donors] (PubMed id 17493347)1, 9 Wu Q.J....Wei X.Q. (2007)
    488. [Polymorphism of human leukocyte antigen-A, B, and DRB1 genes in bone marrow registry donors of Shaanxi province analysis of 14 006 cases] (PubMed id 17288808)1, 9 Liu M.L....Liu S. (2006)
    489. Polymorphism of HLA-DRB1 gene shows no strong association with ulcerative colitis in Chinese patients. (PubMed id 16426241)1, 9 Lu M. and Xia B. (2006)
    490. [The analysis of HLA-A, B and DRB1 allelic polymorphism in Han race population in Lanzhou region of China] (PubMed id 16456797)1, 9 Li C.L....Wei H.L. (2006)
    491. [Polymorphism distribution of HLA-DRB1 gene locus in Han race population in Liaoning of China] (PubMed id 16767683)1, 9 Qu Z....Li J.P. (2006)
    492. [The role of HLA DRB1 genetic polymorphisms in non-Hodgkin's lymphomas] (PubMed id 16786764)1, 9 Kalinka E....Warzocha K. (2005)
    493. HLA-DRB1 allele polymorphosm associated with susceptibility to leukemia in Han nationality of Gansu. (PubMed id 16277843)1, 9 Cao H.X....Zhou L.X. (2005)
    494. CARD15 and HLA DRB1 alleles influence susceptibility and disease localization in Crohn's disease. (PubMed id 15046222)1, 9 Newman B....Siminovitch K. (2004)
    495. HLA-DRB1 allele distribution in polymyalgia rheumatica and giant cell arteritis: influence on clinical subgroups and prognosis. (PubMed id 15305244)1, 9 Martinez-Taboda V.M....Rodriguez-Valverde V. (2004)
    496. Tumor necrosis factor alpha 5'-flanking region, tumor necrosis factor receptor II, and HLA-DRB1 polymorphisms in Japanese patients with rheumatoid arthritis. (PubMed id 10765919)4, 9 Shibue T....Tokunaga K. (2000)
    497. Unique sequences for two HLA-DRB1 genes expressed on distinct DRw6 haplotypes. (PubMed id 1975801)1, 9 Petersdorf E.W.... Hansen J.A. (1990)
    498. MICA polymorphisms and haplotypes with HLA-B and HLA- DRB1 in Koreans. (PubMed id 19895570)1, 9 Sohn Y.H....Kwon O.J. (2010)
    499. Familial disease, the HLA-DRB1 shared epitope and anti-CCP antibodies influence time at appearance of substantial joint damage in rheumatoid arthritis. (PubMed id 19117726)1, 9 Rojas-Villarraga A....Anaya J.M. (2009)
    500. Association study of CCR5 delta 32 polymorphism among the HLA-DRB1 Caucasian population in Northern Parana, Brazil. (PubMed id 18623133)1, 9 Muxel S.M....Ehara Watanabe M.A. (2008)
    501. HLA-DPB1, -DRB1, and -DQB1 polymorphism defined in Ewenki ethnic minority of China Inner Mongolia Autonomous Region. (PubMed id 18001300)1, 9 Su X....Gong M. (2007)
    502. Influence of HLA-DRB1 genes and the shared epitope on genetic susceptibility to rheumatoid arthritis in Taiwanese. (PubMed id 17309132)1, 9 Liu S.C....Huang C.H. (2007)
    503. [HLA-A, B, DRB1 gene polymorphism of Beijing population was studied by high-resolution polymerase chain reaction sequence-based typing] (PubMed id 16456803)1, 9 Deng Y.J....Liu Y. (2006)
    504. HLA-A, HLA-B, and HLA-DRB1 alleles and haplotypes in Naxi and Han populations in southwestern China (Yunnan province). (PubMed id 16451199)1, 9 Shi L....Tokunaga K. (2006)
    505. Complete coding sequences and haplotypic associations of HLA-B*0707, -B*1524, -B*4405, -B*4802, -DRB1*0409, -DRB1*0411, -DRB1*1115, - DRB1*1305, and the novel allele -DRB1*0709. Group-specific amplification of cDNA from DRB1 alleles associated to DRB3 and DRB4. (PubMed id 15896200)1, 9 Vilches C.... DePablo R. (2005)
    506. Association of tumour necrosis factor-alpha, lymphotoxin-alpha and HLA-DRB1 gene polymorphisms with Lofgren's syndrome in Czech patients with sarcoidosis. (PubMed id 15713215)1, 9 Mrazek F....Petrek M. (2005)
    507. HLA-DRB1 genes and disease severity in rheumatoid arthritis in Turkey. (PubMed id 14690140)1, 9 Kinikli G....Tokgoz G. (2003)
    508. HLA-DRB1 genes and susceptibility to rheumatoid arthritis in three ethnic groups from Malaysia. (PubMed id 12482190)1, 9 Kong K.F....Phipps M.E. (2002)
    509. HLA-DRB1 gene transcripts in rheumatoid arthritis. (PubMed id 11359453)1, 9 Kerlan-Candon S....Eliaou J.F. (2001)
    510. Independent contribution of HLA-DRB1 and TNF alpha promoter polymorphisms to the susceptibility to Crohn's disease. (PubMed id 11196680)4, 9 Kawasaki A....Tokunaga K. (2000)
    511. HLA-A, -B, and -DRB1 gene polymorphism in the Miao et hnic group of Hunan, China. (PubMed id 20448347)1, 9 Qian X....Lu G. (2010)
    512. Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis. (PubMed id 18832704)1, 9 Caillier S.J....Oksenberg J.R. (2008)
    513. Association of the HLA-DRB1 gene with premature death, particularly from cardiovascular disease, in patients with rheumatoid arthritis and inflammatory polyarthritis. (PubMed id 18240242)1, 9 Farragher T.M....Barton A. (2008)
    514. A single tumour necrosis factor haplotype influences the response to adalimumab in rheumatoid arthritis. (PubMed id 17673491)1, 9 Miceli-Richard C....Mariette X. (2008)
    515. Meta-analysis of HLA-DRB1 and HLA-DQB1 polymorphisms in Latin American patients with systemic lupus erythematosus. (PubMed id 18295738)1, 9 Castano-Rodriguez N....Anaya J.M. (2008)
    516. Association of the HLA-DRB1 alleles with characteristic MRI features of Asian multiple sclerosis. (PubMed id 18952831)1, 9 Matsuoka T....Kira J. (2008)
    517. Investigating the role of the HLA-Cw*06 and HLA-DRB1 genes in susceptibility to psoriatic arthritis: comparison with psoriasis and undifferentiated inflammatory arthritis. (PubMed id 17728335)1, 9 Ho P.Y....Bruce I.N. (2008)
    518. Associations between HLA-DRB1, RANK, RANKL, OPG, and IL-17 genotypes and disease severity phenotypes in Japanese patients with early rheumatoid arthritis. (PubMed id 17876645)1, 9 Furuya T....Kotake S. (2007)
    519. The polymorphism and haplotype analysis of HLA-A, -B and -DRB1 genes of population in Jiangsu province of China. (PubMed id 18001297)1, 9 Miao K.R....Wang C.Y. (2007)
    520. A second major histocompatibility complex susceptibility locus for multiple sclerosis. (PubMed id 17252545)1, 9 Yeo T.W....Sawcer S. (2007)
    521. [Human leucocyte antigen gene (HLA-A, HLA-B, HLA-DRB1) frequencies in deceased organ donors] (PubMed id 18320121)1, 9 Rodriguez L.M....Garcia L.F. (2007)
    522. The association between the genetic polymorphism of HLA-DQA1, DQB1, and DRB1 and serum alanine aminotransferase levels in chronic hepatitis C in the Chinese population. (PubMed id 18028350)1, 9 Yu R.B....Ge D.F. (2007)
    523. Group-specific amplification of cDNA from DRB1 genes. Complete coding sequences of partially defined alleles and identification of the new alleles DRB1*040602, DRB1*111102, DRB1*080103, and DRB1*0113. (PubMed id 17174751)1, 9 Balas A.... Vicario J.L. (2006)
    524. Influence and interactions of cathepsin D, HLA-DRB1 and APOE on cognitive abilities in an older non-demented population. (PubMed id 16417614)1, 9 Payton A....Pendleton N. (2006)
    525. [HLA-DRB1 gene distribution in Croatian arthritis patients] (PubMed id 16689106)1, 9 Zerjavic N.L....Ivanisevic G. (2005)
    526. Association between migraine and HLA-DRB1 gene polymorphisms. (PubMed id 16362659)1, 9 Rainero I....Pinessi L. (2005)
    527. Polymorphisms of the HLA-B and HLA-DRB1 genes in Thai malaria patients. (PubMed id 15728986)1, 9 Hananantachai H....Tokunaga K. (2005)
    528. [The association of HLA-DRB1 allele polymorphism with the genetic susceptibility to liver cirrhosis due to hepatitis B virus] (PubMed id 12778456)1, 9 Cheng Y.Q....Xiong P. (2003)
    529. Possible association of HLA-DRB1 gene with the autoantibody against myocardial mitochondria ADP/ATP carrier in dilated cardiomyopathy. (PubMed id 12658812)1, 9 Wang Q....Zhang J. (2002)
    530. [Study on the relations between HLA-DRB1 alleles and idiopathic thrombocytopenic purpura in children] (PubMed id 12170464)1, 9 Wang H....Hou H. (2002)
    531. HLA-DRB4 genotyping by PCR-RFLP: diversity in the associations between HLA-DRB4 and DRB1 alleles. (PubMed id 9062971)1, 9 Naruse T.K....Inoko H. (1997)
    532. A possible association between basic amino acids of position 13 of DRB1 chains and autoimmune hepatitis. (PubMed id 1350267)4, 9 Ota M....Inoko H. (1992)
    533. A new HLA-DRB1 allele within the DRw52 supertypic specificity (DRw13- DwHAG): sequencing and direct identification by oligonucleotide typing. (PubMed id 2311644)1, 9 Tiercy J.M.... Mach B. (1990)
    534. Association of HLA DRB1 alleles with juvenile idiopat hic arthritis in Mexicans. (PubMed id 20346252)1, 9 Silva-Ramirez B....Burgos-Vargas R. (2010)
    535. HLA-B, DR and DQ antigens polymorphism in Tunisian pa tients with ankylosing spondylitis (a case-control study). (PubMed id 19655145)1, 9 Kchir M.M....Makni S. (2010)
    536. Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex. (PubMed id 19295542)1, 9 Viken M.K....Lie B.A. (2009)
    537. Confirmation of HLA class II independent type 1 diabetes associations in the major histocompatibility complex including HLA-B and HLA-A. (PubMed id 19143813)1, 9 Howson J.M....Todd J.A. (2009)
    538. HLA class II polymorphism in children with coeliac di sease in Tunisia: is there any influence on clinical manifestation? (PubMed id 19474744)1, 9 Laadhar L....Ben Hariz M. (2009)
    539. Opposing effects of HLA-DRB1*13 alleles on the risk of developing anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis. (PubMed id 19333936)1, 9 LundstrAPm E....Padyukov L. (2009)
    540. TNF, LTA, HSPA1L and HLA-DR gene polymorphisms in HIV-positive patients with hypersensitivity to cotrimoxazole. (PubMed id 19374512)1, 9 Alfirevic A....Pirmohamed M. (2009)
    541. Association of HLA-DRB1, interleukin-6 and cyclin D1 polymorphisms with cervical cancer in the Swedish population--a candidate gene approach. (PubMed id 19585495)1, 9 Castro F.A....Pawlita M. (2009)
    542. Transfer of the shared epitope through microchimerism in women with rheumatoid arthritis. (PubMed id 19117368)1, 9 Rak J.M....Lambert N.C. (2009)
    543. [HLA-A, B, and DRB1 gene polymorphisms in Mongol ethnic group of Inner Mongolia, China] (PubMed id 18244920)1, 9 Shen C.M....Li S.B. (2008)
    544. Associations between genetic factors, tobacco smoking and autoantibodies in familial and sporadic rheumatoid arthritis. (PubMed id 17660221)1, 9 Michou L....Petit-Teixeira E. (2008)
    545. [Expression and analysis of HLA-A, B and DRB1 genes in patients with chronic myelogenous leukemia in Guangdong area] (PubMed id 18718089)1, 9 Wei L....Chong F. (2008)
    546. Human Leukocyte Antigen (HLA)-B, -DRB1 and -DQB1 Allotypes Associated with Disease and Protection in Trachoma Endemic Villages. (PubMed id 18824733)1, 9 Abbas M....West S.K. (2008)
    547. Independent association of tumor necrosis factor polymorphism with type 1 diabetes susceptibility. (PubMed id 19120272)1, 9 Shin H.D....Park Y. (2008)
    548. HLA DRB1, DQB1 and insulin promoter VNTR polymorphisms: interactions and the association with adult-onset diabetes mellitus in Czech patients. (PubMed id 18279373)1, 9 Cejkova P....Zdarsky E. (2008)
    549. A suggestive association of fuchs heterochromic cyclitis with cytotoxic T cell antigen 4 gene polymorphism. (PubMed id 17287608)1, 9 Spriewald B.M....Wenkel H. (2007)
    550. Influence of human leucocyte antigen-DRB1 on the susceptibility to rheumatoid arthritis and on the production of anti-cyclic citrullinated peptide antibodies in a Portuguese population. (PubMed id 16793843)1, 9 Ligeiro D....Branco J. (2007)
    551. Prevalence of HLA DQB1*0602 allele in patients with migraine. (PubMed id 18345414)1, 9 Santos Coelho F.M....Tufik S. (2007)
    552. HLA Dr-Dq haplotypes and the TNFA-308 polymorphism: associations with asthma and allergy. (PubMed id 17686102)1, 9 Munthe-Kaas M.C....Undlien D. (2007)
    553. MHC class I chain-related gene B (MICB) is associated with rheumatoid arthritis susceptibility. (PubMed id 17003176)1, 9 Lopez-Arbesu R.... Gonzalez S. (2007)
    554. The association between HLA genes and radiological erosions in Malaysian patients with rheumatoid arthritis. (PubMed id 17453717)1, 9 Yeap S.S....Phipps M.E. (2007)
    555. New HLA DRB1 and DQB1 haplotypes in a pedigree of familial Graves' disease in Japan. (PubMed id 17785916)1, 9 Sasaki M....Ishikawa S.E. (2007)
    556. Analysis of extended HLA haplotypes in multiple sclerosis and narcolepsy families confirms a predisposing effect for the class I region in Tasmanian MS patients. (PubMed id 17256150)1, 9 Rubio J.P....Foote S.J. (2007)
    557. Three allele combinations associated with multiple sclerosis. (PubMed id 16872485)1, 9 Favorova O.O....Ochs M.F. (2006)
    558. Association of HLA class II DRB1, DPA1 and DPB1 polymorphism with genetic susceptibility to idiopathic dilated cardiomyopathy in Chinese Han nationality. (PubMed id 17060025)1, 9 Liu W....Gan R.T. (2006)
    559. Association between the HLA-DRB1 gene and clinical features of systemic sclerosis in Korea. (PubMed id 16467040)1, 9 Joung C.I....Yoo D.H. (2006)
    560. [Influence of alleles and haplotypes of the main histocompatibility complex on the susceptibility to systemic lupus erythematosus in the Mexican population] (PubMed id 16875346)1, 9 Granados J....Vargas-Alarcon G. (2006)
    561. Association of HLA-DR, -DQ, and vitamin D receptor alleles and haplotypes with tuberculosis in the Venda of South Africa. (PubMed id 16916662)1, 9 Lombard Z....Bornman L. (2006)
    562. Is the association between TNF-alpha-308 A allele and DMT1 independent of HLA-DRB1, DQB1 alleles? (PubMed id 17047287)1, 9 Deja G....Mal/ecka-Tendera E. (2006)
    563. Tumor HLA-DR expression linked to early intrahepatic recurrence of hepatocellular carcinoma. (PubMed id 15688398)1, 9 Matoba K....Oka M. (2005)
    564. [The association of tuberculosis with the specificities of the HLA gene DRB1 in different regions of Tuva] (PubMed id 16130422)1, 9 Pospelova L.E....Mes'ko E.M. (2005)
    565. [Determination of HLA-A, B, and DRB1 gene polymorphism in Monba ethnic group of Xizang Autonomous Region, China] (PubMed id 15952133)1, 9 Zhang H.B....Li S.B. (2005)
    566. Crohn's disease associated CARD15 (NOD2) variants are not involved in the susceptibility to type 1 diabetes. (PubMed id 16198136)1, 9 Ghandil P....Julier C. (2005)
    567. [Polymorphism of human HLA-DRB1 leukocyte antigen alleles and its association to juvenile rheumatoid arthritis in a sample of Colombian mestizo children] (PubMed id 14582328)1, 9 Garavito G....Egea E. (2003)
    568. Different gene loci within the HLA-DR and TNF regions are independently associated with susceptibility and severity in Spanish rheumatoid arthritis patients. (PubMed id 10852383)4, 9 Hajeer A.H....Ollier W.E. (2000)
    569. Risk for Alzheimer's disease in older late-onset cases is associated with HLA-DRB1*03. (PubMed id 10568518)4, 9 Neill D....Perry R. (1999)
    570. Genetic association of the HLA DRB1 gene locus on chromosome 6p21.3 with schizophrenia. (PubMed id 8942447)4, 9 Wright P....Murray R.M. (1996)
    571. Association of LMP2 and LMP7 genes within the major histocompatibility complex with insulin-dependent diabetes mellitus: population and family studies. (PubMed id 7847389)4, 9 Deng G.Y....She J.X. (1995)
    572. (PubMed id 16362107)4, 9 
    573. Search for schizophrenia susceptibility variants at th e HLA-DRB1 locus among a British population. (PubMed id 23053058)1 Halley L....Wei J. (2013)
    574. Brief report: Association of HLA-DRB1*0101/*0405 with susceptibility to anti-melanoma differentiation-associated gene 5 antibody-posit ive dermatomyositis in the Japanese population. (PubMed id 22886382)1 Gono T....Yamanaka H. (2012)
    575. Very high levels of anti-citrullinated protein antibod ies are associated with HLA-DRB1*15 non-shared epitope allele in patients with r heumatoid arthritis. (PubMed id 22307773)1 Laki J....Padyukov L. (2012)
    576. HLA-DRB1*12:02:01 plays a protective role against coro nary artery disease in women of southern Han Chinese descent. (PubMed id 22122841)1 Liu B....Liu S.M. (2012)
    577. Proinflammatory HLA-DRB1*01-haplotype predisposes to S T-elevation myocardial infarction. (PubMed id 22310063)1 Paakkanen R....Sinisalo J. (2012)
    578. A retrospective review of 15 patients with familial my asthenia gravis over a period of 25 years. (PubMed id 22057263)1 Feng H.Y....Huang R.X. (2012)
    579. The role of the HLA-G gene and molecule on the clinica l expression of rheumatologic diseases. (PubMed id 22286648)1 Brenol C.V....Xavier R.M. (2012)
    580. Lapatinib-induced liver injury characterized by class II HLA and Gilbert's syndrome genotypes. (PubMed id 22357454)1 Spraggs C.F....Dollery C.T. (2012)
    581. HLA-DRB1 allele frequencies and C4 copy number variati on in Finnish sarcoidosis patients and associations with disease prognosis. (PubMed id 22074998)1 Wennerstrom A....Selroos O. (2012)
    582. Protective effect of HLA-DRB1 11 and predisposition of HLA-C 04 in the development of severe liver damage in Brazilian patients with c hronic hepatitis C virus infection. (PubMed id 22803655)1 Marangon A.V....Moliterno R.A. (2012)
    583. A genome-wide association study of host genetic determ inants of the antibody response to Anthrax Vaccine Adsorbed. (PubMed id 22658931)1 Pajewski N.M....Kaslow R.A. (2012)
    584. Genetic characterization and susceptibility for sarcoi dosis in Japanese patients: risk factors of BTNL2 gene polymorphisms and HLA cla ss II alleles. (PubMed id 22991420)1 Suzuki H....Mizuki N. (2012)
    585. Clinical Sindbis alphavirus infection is associated wi th HLA-DRB1*01 allele and production of autoantibodies. (PubMed id 22523259)1 Sane J....Vapalahti O. (2012)
    586. Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. (PubMed id 22286218)1 Raychaudhuri S....de Bakker P.I. (2012)
    587. Analysis of human leucocyte antigen genes in Caucasian patients with idiopathic moyamoya angiopathy. (PubMed id 22234791)1 Kraemer M....Heinemann F.M. (2012)
    588. HLA class II DRB1*1302 allele protects against progres sion to cervical intraepithelial neoplasia grade 3: a multicenter prospective co hort study. (PubMed id 22391763)1 Matsumoto K....Yoshikawa H. (2012)
    589. High frequency of human leukocyte antigen class II DRB 1*1602 haplotype in Greek patients with myelodysplastic syndrome and of DRB1*150 1 in the low-risk subgroup. (PubMed id 22244918)1 Kritikou-Griva E....Stavropoulos-Giokas C. (2012)
    590. Association of human leukocyte antigen-DRB1 alleles wi th chronic hepatitis B virus infection in the Han Chinese of Northeast China. (PubMed id 22367481)1 Han Y....Chen L. (2012)
    591. Correlations between HLA-A, HLA-B and HLA-DRB1 allele polymorphisms and childhood susceptibility to acquired aplastic anemia. (PubMed id 22572536)1 Chen C....Xiao L. (2012)
    592. Protective human leucocyte antigen haplotype, HLA-DRB1 *01-B*14, against chronic Chagas disease in Bolivia. (PubMed id 22448298)1 del Puerto F....Hirayama K. (2012)
    593. Association study of human leukocyte antigen-DRB1 alle les with rheumatoid arthritis in south Tunisian patients. (PubMed id 22349877)1 Ben Hamad M....Maalej A. (2012)
    594. HLA-DRB1-DQB1 haplotypes confer susceptibility and res istance to multiple sclerosis in Sardinia. (PubMed id 22509268)1 Cocco E....Marrosu M.G. (2012)
    595. DRB1*12:01 presents a unique subset of epitopes by pre ferring aromatics in pocket 9. (PubMed id 22196942)1 Chow I.T....Kwok W.W. (2012)
    596. Interaction analysis between HLA-DRB1 shared epitope a lleles and MHC class II transactivator CIITA gene with regard to risk of rheumat oid arthritis. (PubMed id 22461888)1 Ronninger M....Padyukov L. (2012)
    597. [Analysis of allele frequencies of HLA-DRB1*12:01:01G and HLA-DRB1*14:01:01G groups]. (PubMed id 22311500)1 He J.J....Yan L.X. (2012)
    598. Three novel alleles at the HLA-DRB1 locus identified b y sequence-based typing. (PubMed id 22119882)1 Frison S....Poli F. (2012)
    599. Association of HLA-DRB1 alleles and neuropsychological function in autism. (PubMed id 21716163)1 Chien Y.L....Chao Y.L. (2012)
    600. A spectrum of susceptibility to rheumatoid arthritis w ithin HLA-DRB1: stratification by autoantibody status in a large UK population. (PubMed id 21881596)1 Mackie S.L....Morgan A.W. (2012)
    601. Anti-citrullinated fibronectin antibodies in rheumatoi d arthritis are associated with human leukocyte antigen-DRB1 shared epitope alle les. (PubMed id 22339947)1 van Beers J.J....Pruijn G.J. (2012)
    602. DRB1*03:01 haplotypes: differential contribution to mu ltiple sclerosis risk and specific association with the presence of intrathecal IgM bands. (PubMed id 22363536)1 de la Concha E.G....Nunez C. (2012)
    603. The ancestry of the HLA-DRB1*15 allele predisposes the Mexican mestizo to the development of aplastic anemia. (PubMed id 22580214)1 Fernandez-Torres J....Lopez-Reyes A. (2012)
    604. Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein. (PubMed id 22860026)1 Bozzacco L....Fenyo D. (2012)
    605. Human leukocyte antigen (HLA)-DRB1*14 is associated wi th a high incidence of acute lymphocytic leukemia. (PubMed id 22868506)1 Zhou M....Miao K. (2012)
    606. A multicentre study of acute kidney injury in severe s epsis and septic shock: association with inflammatory phenotype and HLA genotype . (PubMed id 22701553)1 Payen D....Busson M. (2012)
    607. The HLA-DRB1 gene and Graves disease in Taiwanese chil dren: a case-control and family-based study. (PubMed id 22731780)1 Wu Y.L....Lee Y.J. (2012)
    608. Common and well-documented (CWD) alleles of human leuk ocyte antigen-A, -B, -C, -DRB1, and -DQB1 loci for the Chinese Han population do not quite correlate with the ASHI CWD alleles. (PubMed id 21712058)1 He J....Hou J. (2012)
    609. The influence of the HLA-DRB1 and HLA-DQB1 allele hete rogeneity on disease risk and severity in Iranian patients with multiple scleros is. (PubMed id 22404765)1 Kollaee A....Zamani M. (2012)
    610. Association between Parkinson's disease and the HLA-DR B1 locus. (PubMed id 22807207)1 Ahmed I....Elbaz A. (2012)
    611. HIV-1 Gag-virus-like particles induce natural killer c ell immune responses via activation and maturation of dendritic cells. (PubMed id 21778700)1 Chang M.O....Takaku H. (2012)
    612. HLA-dependent hypersensitivity reaction to nevirapine in Chinese Han HIV-infected patients. (PubMed id 21902584)1 Gao S....Dong B. (2012)
    613. Amino acid position 11 of HLA-DRb1 is a major determin ant of chromosome 6p association with ulcerative colitis. (PubMed id 22170232)1 Achkar J.P....Duerr R.H. (2012)
    614. Inflammatory bowel disease: susceptibility and disease heterogeneity revealed by human leukocyte antigen genotyping. (PubMed id 22224635)1 Bouzid D....Masmoudi H. (2012)
    615. Late onset myasthenia gravis is associated with HLA DR B1*15:01 in the Norwegian population. (PubMed id 22590574)1 Maniaol A.H....Harbo H.F. (2012)
    616. Associations of HLA DR and DQ molecules with Lyme borr eliosis in Latvian patients. (PubMed id 22892251)1 Kovalchuka L....Krumina A. (2012)
    617. Intracellular overexpression of HIV-1 Nef impairs diff erentiation and maturation of monocytic precursors towards dendritic cells. (PubMed id 22808111)1 Guo Y....Zhang H.T. (2012)
    618. A genome-wide association study in Han Chinese identif ies multiple susceptibility loci for IgA nephropathy. (PubMed id 22197929)1 Yu X.Q....Liu J.J. (2012)
    619. HLA-DRB1*1501 and HLA-DQB1*0301 alleles are positively associated with HPV16 infection-related Kazakh esophageal squamous cell carcino ma in Xinjiang China. (PubMed id 22588649)1 Hu J....Li F. (2012)
    620. Classical HLA-DRB1 and DPB1 alleles account for HLA as sociations with primary biliary cirrhosis. (PubMed id 22573116)1 Invernizzi P....Seldin M.F. (2012)
    621. Association of HLA-DRB1*14 with rheumatic heart disease patients from Chandigarh, North India. (PubMed id 22204478)1 Toor D....Chakraborti A. (2012)
    622. Pediatric adrenocortical tumors: morphological diagno stic criteria and immunohistochemical expression of matrix metalloproteinase ty pe 2 and human leucocyte-associated antigen (HLA) class II antigens. Results fr om the Italian Pediatric Rare Tumor (TREP) Study project. (PubMed id 21820153)1 Magro G....Alaggio R. (2012)
    623. Investigation of the possible association between the HLA antigens and idiopathic thrombocytopenic purpura (ITP). (PubMed id 21806423)1 Negi R.R....Luthra-Guptasarma M. (2012)
    624. Potential association of vitamin D receptor polymorphi sm Taq1 with multiple sclerosis. (PubMed id 21816760)1 Cox M.B....Lechner-Scott J. (2012)
    625. HLA alleles and amino-acid signatures of the peptide- binding pockets of HLA molecules in vitiligo. (PubMed id 21833019)1 Singh A....Rani R. (2012)
    626. Human leukocyte antigen class I (A, B, C) and II (DRB1 ) diversity in the black and Caucasian South African population. (PubMed id 22074999)1 Paximadis M....Puren A. (2012)
    627. Interaction of HLA-DRB1*03 and smoking for the develop ment of anti-Jo-1 antibodies in adult idiopathic inflammatory myopathies: a Euro pean-wide case study. (PubMed id 22186711)1 Chinoy H....Cooper R.G. (2012)
    628. Age-related islet autoantibody incidence in offspring of patients with type 1 diabetes. (PubMed id 22289814)1 Ziegler A.G. and Bonifacio E. (2012)
    629. Influence of HLA alleles in response to treatment with pegylated interferon-alpha and ribavirin in patients with chronic hepatitis C. (PubMed id 22284614)1 Marangon A.V....Silva G.F. (2012)
    630. Novel associations for hypothyroidism include known au toimmune risk loci. (PubMed id 22493691)1 Eriksson N....Do C.B. (2012)
    631. The correlation of HLA allele frequencies and HLA anti bodies in sensitized kidney transplantation candidates. (PubMed id 22310618)1 Fu Q....Liu L. (2012)
    632. HLA-DRB1,-DQA1 and -DQB1 allele and haplotype frequenc ies in female patients with early onset breast cancer. (PubMed id 21720852)1 Mahmoodi M....Amirzargar A. (2012)
    633. HLA, PTPN22 and PD-1 associations as markers of autoim munity in neuromyelitis optica. (PubMed id 21908482)1 Asgari N....Lillevang S.T. (2012)
    634. HLA-DQ association and allele competition in Chinese n arcolepsy. (PubMed id 22862152)1 Han F....Mignot E. (2012)
    635. Frequency of HLA-DRB1 gene alleles in patients with mu ltiple sclerosis in a Lithuanian population. (PubMed id 22370504)1 Balnyte R....Vitkauskiene A. (2012)
    636. Frequency of autoantibodies and correlation with HLA-D RB1 genotype in sporadic inclusion body myositis (s-IBM): a population control s tudy. (PubMed id 22554526)1 Rojana-Udomsart A....Mastaglia F. (2012)
    637. High-resolution HLA-DRB1 genotyping in an Australian i nclusion body myositis (s-IBM) cohort: an analysis of disease-associated alleles and diplotypes. (PubMed id 22633068)1 Rojana-udomsart A....Mastaglia F. (2012)
    638. Association of HLA genes with clinical outcomes of ANC A-associated vasculitis. (PubMed id 22595829)1 Chang D.Y....Zhao M.H. (2012)
    639. HLA-DRB1 allele distribution and its relation to rheum atoid arthritis in eastern Black Sea Turkish population. (PubMed id 21246357)1 Ucar F....Karaca A. (2012)
    640. Quantitative effect of HLA-DRB1 alleles to ACPA levels in Japanese rheumatoid arthritis: no strong genetic impact of shared epitope to ACPA levels after stratification of HLA-DRB1*09:01. (PubMed id 22233603)1 Terao C....Mimori T. (2012)
    641. GWAS identifies novel susceptibility loci on 6p21.32 a nd 21q21.3 for hepatocellular carcinoma in chronic hepatitis B virus carriers. (PubMed id 22807686)1 Li S....Zhou W. (2012)
    642. HLA class II susceptibility to cervical cancer among T unisian women. (PubMed id 22863772)1 Ben Othmane Y....Yacoubi Loueslati B. (2012)
    643. HLA-DRB1*15:01 and multiple sclerosis: a female associ ation? (PubMed id 22127897)1 Irizar H....Otaegui D. (2012)
    644. Mapping the HLA-DO/HLA-DM complex by FRET and mutagene sis. (PubMed id 22733780)1 Yoon T....Mellins E.D. (2012)
    645. Vitamin D receptor gene polymorphisms and HLA DRB1*04 cosegregation in Saudi type 2 diabetes patients. (PubMed id 22219324)1 Al-Daghri N.M....Clerici M. (2012)
    646. The genetic variants at the HLA-DRB1 gene are associat ed with primary IgA nephropathy in Han Chinese. (PubMed id 22578019)1 Jiyun Y....Zhenglin Y. (2012)
    647. The influence of the HLA-DRB, HLA-DQB and polymorphic positions of the HLA-DRb1 and HLA-DQb1 molecules on risk of Iranian type 1 diabe tes mellitus patients. (PubMed id 22494469)1 Sayad A....Zamani M. (2012)
    648. HLA-A and HLA-DRB1 amino acid polymorphisms are associ ated with susceptibility and protection to pulmonary tuberculosis in a Greek pop ulation. (PubMed id 22504415)1 Magira E.E....Monos D.S. (2012)
    649. Relationship of HLA-DRB1 alleles with hepatocellular c arcinoma development in chronic hepatitis B patients. (PubMed id 22499074)1 Jin Y.J....Yang S.H. (2012)
    650. Related transplantation with HLA-1 Ag mismatch in the GVH direction and HLA-8/8 allele-matched unrelated transplantation: a nationwide retrospective study. (PubMed id 22042692)1 Kanda J....Kanda Y. (2012)
    651. Influence of HLA-DRB1 and HLA-DQB1 alleles on IgG anti body response to the P. vivax MSP-1, MSP-3a and MSP-9 in individuals from Brazil ian endemic area. (PubMed id 22649493)1 Lima-Junior J.C....de Oliveira-Ferreira J. (2012)
    652. [Analysis of HLA-A, B, and DRB1 polymorphism and genet ic distance in Han population living in Yantai and Weihai regions of Shandong pr ovince]. (PubMed id 22487840)1 Zhang Y....Zhu C.F. (2012)
    653. Association of HLA-DRB1*15 allele and CSF oligoclonal bands in a Spanish multiple sclerosis cohort. (PubMed id 21418440)1 Romero-Pinel L....Arbizu T. (2011)
    654. Pancreatic autoantibodies, HLA DR and PTPN22 polymorph isms in first degree relatives of patients with type 1 diabetes and multiethnic background. (PubMed id 22068554)1 Barone B....Oliveira J.E. (2011)
    655. Association of HLA and TNF polymorphisms with the out come of HBV infection in the South Indian population. (PubMed id 21593777)1 Fletcher G.J....Abraham P. (2011)
    656. Characterization of three novel HLA-DRB1 alleles, DRB 1*03:55, *11:46:02 and *04:92, by exon 2, 3 and 4 sequencing-based typing. (PubMed id 21676191)1 Balas A....Vicario J.L. (2011)
    657. Non-HLA genes modulate the risk of rheumatoid arthrit is associated with HLA-DRB1 in a susceptible North American Native population. (PubMed id 21614018)1 El-Gabalawy H.S....Siminovitch K.A. (2011)
    658. Human leukocyte antigen class II susceptibility confe rring alleles among non-insulin dependent diabetes mellitus patients. (PubMed id 21276381)1 Tipu H.N....Bashir M.M. (2011)
    659. HPV-16 and HLA-DRB1 alleles are associated with cervi cal carcinoma in Mexican Mestizo women. (PubMed id 21911185)1 Alaez-Verson C....Gorodezky-Lauferman C. (2011)
    660. Association of HLA-DRB alleles and pulmonary tubercul osis in North Chinese patients. (PubMed id 21751159)1 Shi G.L....Song C.X. (2011)
    661. Polymorphism of human leukocyte antigen-A, -B, and -D RB1 in a Moroccan population from Casablanca: study of the allelic and the hapl otypic frequencies. (PubMed id 21659045)1 Kabbaj M....Bennani S. (2011)
    662. HLA DRB1*1503 allelic haplotype predominance and asso ciated immunodysregulation in systemic lupus erythematosus. (PubMed id 21497601)1 Suggs M.J....Cruse J.M. (2011)
    663. Conformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchang e. (PubMed id 22084083)1 Painter C.A....Stern L.J. (2011)
    664. HLA-DRB1*13:99, a novel HLA-DRB1*13 allele identified by sequence-based typing. (PubMed id 21388361)1 Ko S.Y....Kwon O.J. (2011)
    665. [Distribution of HLA specificity frequencies in patien ts with cystic echinococcosis]. (PubMed id 22308705)1 Lukmanova G.I....Lukmanova L.I. (2011)
    666. HLA-DRB1*0407 and *1304 are risk factors for sclerode rma renal crisis. (PubMed id 21280007)1 Nguyen B....Assassi S. (2011)
    667. [Review of research approach on allergens of Shuanghu anglian injection and its important research strategy of susceptibility gene]. (PubMed id 21809595)1 Zhao Y....Li Y. (2011)
    668. HLA-DQ A1, -DQB1 and -DRB1 gene polymorphism--in Mala y type 1 diabetes mellitus patients and their use for risk prediction. (PubMed id 22106694)1 Rohana A.G....Khalid B.A. (2011)
    669. Single-nucleotide polymorphisms in HLA- and non-HLA g enes associated with the development of antibodies to interferon-I^ therapy in m ultiple sclerosis patients. (PubMed id 21502966)1 Weber F....Hemmer B. (2011)
    670. Identification of novel genetic markers associated wit h clinical phenotypes of systemic sclerosis through a genome-wide association st rategy. (PubMed id 21779181)1 Gorlova O....Martin J. (2011)
    671. Misdirection of membrane trafficking by HIV-1 Vpu and Nef: Keys to viral virulence and persistence. (PubMed id 21922073)1 Tokarev A. and Guatelli J. (2011)
    672. Predicting arthritis outcomes--what can be learned fr om the Leiden Early Arthritis Clinic? (PubMed id 20639266)1 de Rooy D.P....van der Helm-van Mil A.H. (2011)
    673. [Association of HLA DRB1 polymorphism with susceptibi lity to myelodysplastic syndrome and aplastic anemia in Chinese Han population] . (PubMed id 21644227)1 Huo M.R....Li D. (2011)
    674. Weak association of anti-sperm antibodies and strong association of familial cryptorchidism/infertility with HLA-DRB1 polymorphisms in prepubertal Ukrainian boys. (PubMed id 21955839)1 Kurpisz M....Kusnierczyk P. (2011)
    675. HLA-class II genes in Mexican Amerindian Mayas: relat edness with Guatemalan Mayans and other populations. (PubMed id 20923326)1 Vargas-AlarcA^n G....Arnaiz-Villena A. (2011)
    676. The significance of HLA DRB1*1501 and oligoclonal band s in multiple sclerosis: clinical features and disability. (PubMed id 22112985)1 Balnyte R....Vitkauskiene A. (2011)
    677. Novel alleles of HLA-DQ and -DR loci show association with recurrent miscarriages among South Indian women. (PubMed id 21325036)1 Aruna M....Reddy B.M. (2011)
    678. Frequency of HLA-A, -B and -DRB1 specificities and ha plotypic associations in the population of Castilla y LeA^n (northwest-central S pain). (PubMed id 21929573)1 Alcoceba M....GonzA!lez M. (2011)
    679. Correlation between HLA-DRB1, HLA-DQB1 polymorphism a nd autoantibodies against angiotensin AT(1) receptors in Chinese patients with essential hypertension. (PubMed id 21557256)1 Zhu F....Liao Y. (2011)
    680. Two novel HLA class II alleles, DRB1*11:96 and DQB1*02:01:03, identified in Koreans. (PubMed id 21395562)1 Lee K.W. (2011)
    681. Study of the frequency of HLA-DRB1 alleles in Brazili an patients with rheumatoid arthritis. (PubMed id 21952999)1 Usnayo M.J....Pinheiro G.d.a. .R. (2011)
    682. Chronic cerebrospinal vascular insufficiency is not a ssociated with HLA DRB1*1501 status in multiple sclerosis patients. (PubMed id 21340025)1 Weinstock-Guttman B....Ramanathan M. (2011)
    683. Association of atherosclerotic cerebral infarction an d human leukocyte antigen-DRB in a North Chinese Han population. (PubMed id 21891926)1 Liu S.Y....Han X.M. (2011)
    684. Interaction of HLA-DRB1*1501 allele and TNF-alpha -30 8 G/A single nucleotide polymorphism in the susceptibility to multiple sclerosi s. (PubMed id 21396892)1 Shahbazi M....Rshaidbaghan A. (2011)
    685. Immunogenetic aspects of erosive osteoarthritis of th e hand in patients from northern Italy. (PubMed id 20919945)1 Ramonda R....Punzi L. (2011)
    686. Bimodal distribution of RNA expression levels in huma n skeletal muscle tissue. (PubMed id 21299892)1 Mason C.C....Bogardus C. (2011)
    687. The association of HLA-DRB1 alleles with antineutroph il cytoplasmic antibody-associated systemic vasculitis in Chinese patients. (PubMed id 21354458)1 Luo H....Zhao M.H. (2011)
    688. Affinity maturation of human CD4 by yeast surface dis play and crystal structure of a CD4-HLA-DR1 complex. (PubMed id 21900604)1 Wang X.X....Mariuzza R.A. (2011)
    689. Association of polycystic ovarian syndrome with human leukocyte antigen polymorphism in Korean women. (PubMed id 21851420)1 Kim J.J....Roh E.Y. (2011)
    690. HLA-DRBeta1, circulating Th1/Th2 cytokines and immuno logical homunculus in coronary atherosclerosis. (PubMed id 21358010)1 Mostafazadeh A....Bijani A. (2011)
    691. HLA-DRB1*04:02, DRB1*08:04 and DRB1*14 alleles associ ated to pemphigus vulgaris in southeastern Brazilian population. (PubMed id 21554253)1 Weber R....Miziara I.D. (2011)
    692. Frequency of HLA-DRB1 alleles in rheumatoid arthritis patients in Zahedan, southeast Iran. (PubMed id 21422655)1 Sandoughi M....Hashemi M. (2011)
    693. Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European suscepti bility loci. (PubMed id 21452313)1 Freudenberg J....Bae S.C. (2011)
    694. The association of HLA class II DR B1 alleles with HC V infection in Egyptian children. (PubMed id 21429451)1 Yosry A....Ghoneim M.A. (2011)
    695. HLA-DRB1/DQB1 susceptibility for autoimmune polygland ular syndrome type II and III in south of Tunisia. (PubMed id 21652028)1 Fourati H....Masmoudi H. (2011)
    696. Distribution of human leucocyte antigen-A, -B and -DR alleles and haplotypes at high resolution in the population from Jiangsu provinc e of China. (PubMed id 21816002)1 Qin Qin P....Jie S. (2011)
    697. HLA-DRB1 shared epitope genotyping using the revised c lassification and its association with circulating autoantibodies, acute phase r eactants, cytokines and clinical indices of disease activity in a cohort of Sout h African rheumatoid arthritis patients. (PubMed id 21978430)1 Meyer P.W....Anderson R. (2011)
    698. HLA class II alleles as markers of tuberculosis susce ptibility and resistance. (PubMed id 21251479)1 Duarte R....Martins B. (2011)
    699. The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients. (PubMed id 21569485)1 Luo H....Zhao M.H. (2011)
    700. A genome-wide association study identifies two new ris k loci for Graves' disease. (PubMed id 21841780)1 Chu X....Song H.D. (2011)
    701. Black patients of African descent and HLA-DRB1*15:03 frequency overrepresented in epidermolysis bullosa acquisita. (PubMed id 21833018)1 Zumelzu C....Prost-Squarcioni C. (2011)
    702. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    703. HLA class II DPB1 and DRB1 polymorphisms associated w ith genetic susceptibility to beryllium toxicity. (PubMed id 21186201)1 Rosenman K.D....Monos D. (2011)
    704. HLA class II alleles and chronic hepatitis C virus in fection. (PubMed id 21535077)1 Cangussu L.O....Gerbase-DeLima M. (2011)
    705. The investigation of HLA microsatellites influence in predisposition to sarcoidosis among Croatians. (PubMed id 21796887)1 GrubiA8 Z....Zunec R. (2011)
    706. Electrostatic modifications of the human leukocyte an tigen-DR P9 peptide-binding pocket and susceptibility to primary sclerosing cho langitis. (PubMed id 21413052)1 Hov J.R....Karlsen T.H. (2011)
    707. Smoking and two human leukocyte antigen genes interac t to increase the risk for multiple sclerosis. (PubMed id 21303861)1 HedstrAPm A.K....Alfredsson L. (2011)
    708. Increased frequencies of myelin oligodendrocyte glyco protein/MHC class II-binding CD4 cells in patients with multiple sclerosis. (PubMed id 21653833)1 Raddassi K....Hafler D.A. (2011)
    709. Genome-wide association study identifies susceptibili ty loci for IgA nephropathy. (PubMed id 21399633)1 Gharavi A.G....Lifton R.P. (2011)
    710. Analysis of the complete cDNA sequences of HLA-DRB1 a lleles with group-specific amplification primers in the Chinese Han population. (PubMed id 21388356)1 Zhu F....Yan L. (2011)
    711. Predictors of associated autoimmune diseases in famil ies with type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium. (PubMed id 21744463)1 WAogner A.M....Mauricio D. (2011)
    712. Endometriosis and autoimmune disease: association of susceptibility to moderate/severe endometriosis with CCL21 and HLA-DRB1. (PubMed id 20797713)1 Sundqvist J....D'Hooghe T.M. (2011)
    713. Genome-wide meta-analysis identifies novel multiple sc lerosis susceptibility loci. (PubMed id 22190364)1 Patsopoulos N.A....de Bakker P.I. (2011)
    714. Common viruses associated with lower pediatric multip le sclerosis risk. (PubMed id 21646624)1 Waubant E....James J.A. (2011)
    715. HLA association in SLE patients from Lahore-Pakistan. (PubMed id 21342137)1 Hussain N....Hasnain S. (2011)
    716. HLA-DRB1 may be antagonistically regulated by the coor dinately evolved promoter and 3'-UTR under stabilizing selection. (PubMed id 22028790)1 Liu B....Xu A. (2011)
    717. Immunosuppressive CD14+HLA-DR(low)/- monocytes in B-c ell non-Hodgkin lymphoma. (PubMed id 21063024)1 Lin Y....Dietz A.B. (2011)
    718. Characterization of 236 novel alleles at the HLA-A, - B, -C, -DRB1, -DQB1 and -DPB1 loci from China Marrow Donor Program. (PubMed id 21732917)1 Li J....Yi X. (2011)
    719. Association of the HLA-DRB1 locus with syphilis in a Chinese population. (PubMed id 21411354)1 Jiang H.W....Zhang F.R. (2011)
    720. Comparisons of clinical features of HLA-DRB1*07 positi ve and negative vitiligo patients in Chinese Han population. (PubMed id 21241376)1 Hu D.Y....Zhang X.J. (2011)
    721. Human leukocyte antigens class II genes are associate d with cancer development in the autoimmune rheumatic diseases. (PubMed id 21888287)1 Miranda-Duarte A....Vill A.R. (2011)
    722. Faster REM sleep EEG and worse restedness in older in somniacs with HLA DQB1*0602. (PubMed id 21292329)1 Zeitzer J.M....Friedman L. (2011)
    723. Association of HLA class II alleles and CTLA-4 polymo rphism with type 1 diabetes. (PubMed id 21422625)1 Ei Wafai R.J....Fakhoury H. (2011)
    724. Acquisition of the rheumatoid arthritis HLA shared epi tope through microchimerism. (PubMed id 21360493)1 Yan Z....Nelson J.L. (2011)
    725. Clinical and genetic characteristics of patients with type 1 diabetes associated with interferon therapy. (PubMed id 21270202)1 Nakanishi K. and Saitoh S. (2011)
    726. Association between T-lymphocyte regulatory gene CTLA 4 single nucleotide polymorphism at position 49 in exon 1 and HLA-DRB1*08 in Ja panese patients with psoriasis vulgaris. (PubMed id 21316924)1 Muto M....Ichimiya M. (2011)
    727. A large-scale association study identified multiple HL A-DRB1 alleles associated with ACPA-negative rheumatoid arthritis in Japanese su bjects. (PubMed id 21873689)1 Terao C....Mimori T. (2011)
    728. Conformational analysis of the I9I9I!83-99 (Phe91) and I9I9I!83-99 (Tyr91) peptide analogues and study of their interactions with the HLA -DR2 and human TCR receptors by using molecular dynamics. (PubMed id 21898163)1 Potamitis C....GoliA8 Grdadolnik S. (2011)
    729. Effect of donor-recipient HLA matching at HLA A, B, C , and DRB1 on outcomes after umbilical-cord blood transplantation for leukaemia and myelodysplastic syndrome: a retrospective analysis. (PubMed id 21982422)1 Eapen M.... . (2011)
    730. HLA-DRB1 gene polymorphism is associated with idiopat hic dilated cardiomyopathy: a meta-analysis. (PubMed id 21709571)1 Deng J....Li X. (2011)
    731. [HLA-DRB1 typing in Caucasians patients with neuromye litis optica]. (PubMed id 21748712)1 Blanco Y....Saiz A. (2011)
    732. Association of HLA-A*02:06 and HLA-DRB1*04:05 with cl inical subtypes of juvenile idiopathic arthritis. (PubMed id 21179106)1 Yanagimachi M....Yokota S. (2011)
    733. Multiple sclerosis in a patient with membranous glome rulopathy: is vitamin D deficiency the culprit in the presence of HLA DRB1*1501 allele? (PubMed id 20876154)1 Sivaramakrishnan R....Gupta S. (2011)
    734. HLA-A, -B, -C, -DQB1, and -DRB1,3,4,5 allele and hapl otype frequencies in the Costa Rica Central Valley Population and its relations hip to worldwide populations. (PubMed id 20937338)1 Arrieta-BolaA+os E....Madrigal J.A. (2011)
    735. HLA associations with multiple sclerosis in Greece. (PubMed id 21741664)1 Kouri I....Pelidou S.H. (2011)
    736. A novel HLA-DRB1 allele: DRB1*15:02:08. (PubMed id 21726205)1 Sun Y....Du K. (2011)
    737. Genetic predictors of 25-hydroxyvitamin D levels and r isk of multiple sclerosis. (PubMed id 21431378)1 Simon K.C....Ascherio A. (2011)
    738. Association between HLA-DRB1 and myasthenia gravis in a northern Han Chinese population. (PubMed id 21924912)1 Xie Y.C....Wang D.X. (2011)
    739. Distribution of the HLA class II frequency alleles in patients with leprosy from the mid-west of Brazil. (PubMed id 21599852)1 Lavado-Valenzuela R....Caballero A. (2011)
    740. Variation in effects of non-Hodgkin lymphoma risk fact ors according to the human leukocyte antigen (HLA)-DRB1*01:01 allele and ancestr al haplotype 8.1. (PubMed id 22096508)1 Wang S.S....Hartge P. (2011)
    741. Meta-analysis identifies 29 additional ulcerative col itis risk loci, increasing the number of confirmed associations to 47. (PubMed id 21297633)1 Anderson C.A....Rioux J.D. (2011)
    742. Heterogeneity at the HLA-DRB1 allelic variation locus does not influence multiple sclerosis disease severity, brain atrophy or cogni tion. (PubMed id 21149397)1 Van der Walt A....Butzkueven H. (2011)
    743. HLA-Cw*1202-B*5201-DRB1*1502 Haplotype Increases Risk for Ulcerative Colitis but Reduces Risk for Crohn's Disease. (PubMed id 21699788)1 Okada Y....Kubo M. (2011)
    744. Major histocompatibility complex and strong human leuk ocyte antigen-DRB1 and gender association with Vogt-Koyanagi-Harada syndrome in Mexican Mestizos. (PubMed id 21964432)1 Alaez C....Gorodezky C. (2011)
    745. HLA-DRB1*010101 allele is closely associated with poor virological response to lamivudine therapy in patients with chronic hepatitis B . (PubMed id 22156484)1 Jin Y.J....Yang S.H. (2011)
    746. HLA genes in Wayu Amerindians from Colombia. (PubMed id 20923327)1 Silvera C....Arnaiz-Villena A. (2011)
    747. HLA-A, HLA-B, and HLA-DRB1 allele distribution in a l arge Armenian population sample. (PubMed id 21501120)1 Matevosyan L....Jordan F. (2011)
    748. HLA-DRB1 confers increased risk of pediatric-onset MS in children with acquired demyelination. (PubMed id 21288988)1 Disanto G....Bar-Or A. (2011)
    749. Association of the HLA-DRB1 epitope LA(67, 74) with r heumatoid arthritis and citrullinated vimentin binding. (PubMed id 22094856)1 Freed B.M....Aubrey M.T. (2011)
    750. Susceptibility to aplastic anemia is associated with HLA-DRB1*1501 in an aboriginal population in Sabah, Malaysia. (PubMed id 21762745)1 Dhaliwal J.S....Murad S. (2011)
    751. Genetic variants in the HLA-DRB1 gene are associated w ith Kashin-Beck disease in the Tibetan population. (PubMed id 21739420)1 Shi Y....Yang Z. (2011)
    752. HLA DRB1*1501 is only modestly associated with lesion burden at the first demyelinating event. (PubMed id 21621859)1 Horakova D....Ramanathan M. (2011)
    753. HLA-DRB1 reduces the risk of type 2 diabetes mellitus by increased insulin secretion. (PubMed id 21484216)1 Williams R.C....Bogardus C. (2011)
    754. HLA-DRB1 association with schizophrenia in Saudi Arabi an patients. (PubMed id 22121859)1 Kadasah S....Tariq M. (2011)
    755. Spinal cord involvement in multiple sclerosis: A corr elative MRI and high-resolution HLA-DRB1 genotyping study. (PubMed id 20884011)1 Qiu W....Kermode A.G. (2011)
    756. The HLA class II Allele DRB1*1501 is over-represented in patients with idiopathic pulmonary fibrosis. (PubMed id 21373184)1 Xue J....Duncan S.R. (2011)
    757. DRB1*15 allele is a risk factor for PR3-ANCA disease in African Americans. (PubMed id 21617122)1 Cao Y....Preston G.A. (2011)
    758. Association of TNFAIP3 interacting protein 1, TNIP1 w ith systemic lupus erythematosus in a Japanese population: a case-control assoc iation study. (PubMed id 20849588)1 Kawasaki A....Tsuchiya N. (2010)
    759. HLA class II alleles and multiple sclerosis in Tunisi an patients. (PubMed id 20691532)1 Messadi A....Gritli N. (2010)
    760. Combined effects of smoking, anti-EBNA antibodies, an d HLA-DRB1*1501 on multiple sclerosis risk. (PubMed id 20375311)1 Simon K.C....Ascherio A. (2010)
    761. Acquired haemophilia caused by non-haemophilic factor VIII gene variants. (PubMed id 20054547)1 Tiede A....Ganser A. (2010)
    762. Human leucocyte antigen class II genotype in suscepti bility and resistance to co-amoxiclav-induced liver injury. (PubMed id 20800921)1 Donaldson P.T....Aithal G.P. (2010)
    763. Extended LTA, TNF, LST1 and HLA gene haplotypes and t heir association with rubella vaccine-induced immunity. (PubMed id 20668555)1 Ovsyannikova I.G....Poland G.A. (2010)
    764. Molecular analysis of HLA Class I and Class II genes in four indigenous Malaysian populations. (PubMed id 20003135)1 Jinam T.A....Phipps M.E. (2010)
    765. Serum Interleukin-4 and Total Immunoglobulin E in Non atopic Alopecia Areata Patients and HLA-DRB1 Typing. (PubMed id 20671941)1 Attia E.A....Sefin A. (2010)
    766. The role of tumor necrosis factor alpha G-308A polymo rphisms in the course of pulmonary sarcoidosis. (PubMed id 20070603)1 Wijnen P.A....Drent M. (2010)
    767. Pemphigus vulgaris in White Europeans is linked with HLA Class II allele HLA DRB1*1454 but not DRB1*1401. (PubMed id 19847191)1 Saha M....Groves R.W. (2010)
    768. Haplotype analysis discriminates genetic risk for DR3 -associated endocrine autoimmunity and helps define extreme risk for Addison's disease. (PubMed id 20631027)1 Baker P.R....Eisenbarth G.S. (2010)
    769. Genetic association of htSNPs across the major histoc ompatibility complex with rheumatoid arthritis in an African-American populatio n. (PubMed id 19741715)1 Reynolds R.J....Bridges S.L. (2010)
    770. Frequency and impact of obstetric complications prior and subsequent to unexplained secondary recurrent miscarriage. (PubMed id 20395221)1 Nielsen H.S....Christiansen O.B. (2010)
    771. Cumulative association of 22 genetic variants with se ropositive rheumatoid arthritis risk. (PubMed id 20233754)1 Karlson E.W....Plenge R.M. (2010)
    772. HLA-Class II in Latin American patients with type 1 d iabetes. (PubMed id 20561992)1 Rojas-Villarraga A....Anaya J.M. (2010)
    773. High frequency of low-risk human leukocyte antigen cl ass II genotypes in latent celiac disease. (PubMed id 21075156)1 Schirru E....Congia M. (2010)
    774. Mold-sensitivity in children with moderate-severe ast hma is associated with HLA-DR and HLA-DQ. (PubMed id 20486920)1 Knutsen A.P....Shah M.R. (2010)
    775. Leprosy and the adaptation of human toll-like recepto r 1. (PubMed id 20617178)1 Wong S.H....Vannberg F.O. (2010)
    776. A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01. (PubMed id 20593013)1 Cree B.A.... . (2010)
    777. Parent-of-origin effects at the major histocompatibil ity complex in multiple sclerosis. (PubMed id 20634196)1 Chao M.J....Ebers G.C. (2010)
    778. Distributions of human leukocyte antigen-A, -B, and - DRB1 alleles and haplotypes based on 46,915 Taiwanese donors. (PubMed id 20493227)1 Lai M.J....Yang K.L. (2010)
    779. [Polymorphism of HLA-DRB1 and -DQB1 alleles among you ng women with cervical squamous cell carcinoma and its relation with human papi llomavirus type 16 infection]. (PubMed id 21029659)1 Hu Y....Shuai C.X. (2010)
    780. High frequency of the IL-2 -330 T/HLA-DRB1*1501 haplo type in patients with multiple sclerosis. (PubMed id 20594918)1 Shahbazi M....Shahbazi S. (2010)
    781. HLA genotype in patients with acquired haemophilia A. (PubMed id 20536993)1 Pavlova A....Oldenburg J. (2010)
    782. Association of the human leucocyte antigen region wit h susceptibility to Parkinson's disease. (PubMed id 20462916)1 Saiki M....Goris A. (2010)
    783. [Immune polymorphism analysis of HLA class II antigen s in ulcer diseases associated with Helicobacter pylori in children]. (PubMed id 20405713)1 Nizhevich A.A....Tsyglintseva N.P. (2010)
    784. Clinical and genetic characteristics of patients with autoimmune thyroid disease with anti-islet autoimmunity. (PubMed id 20825955)1 Moriguchi M....Ikegami H. (2010)
    785. Impact of highly conserved HLA haplotype on acute gra ft-versus-host disease. (PubMed id 20335219)1 Morishima S....Morishima Y. (2010)
    786. Presence or absence of a known diabetic ketoacidosis precipitant defines distinct syndromes of 'A-beta+' ketosis-prone dia betes based on long-term beta-cell function, human leukocyte antigen class II a lleles, and sex predilection. (PubMed id 20170930)1 Nalini R....Balasubramanyam A. (2010)
    787. New classification of the shared epitope in rheumatoi d arthritis: impact on the production of various anti-citrullinated protein ant ibodies. (PubMed id 19920092)1 Gyetvai A....Lakos G. (2010)
    788. HLA-DR genotypes influence age at disease onset in ch ildren and juveniles with type 1 diabetes mellitus. (PubMed id 20371654)1 Awa W.L....Holl R.W. (2010)
    789. Immunogenetic characteristics of patients with autoim mune gastritis. (PubMed id 20082482)1 Oksanen A.M....Partanen J.A. (2010)
    790. The type 1 diabetes - HLA susceptibility interactome- -identification of HLA genotype-specific disease genes for type 1 diabetes. (PubMed id 20221424)1 Brorsson C....Pociot F. (2010)
    791. Anti-citrullinated protein antibody (ACPA) in rheumat oid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione S-transferase in a cross-sectional study . (PubMed id 21087494)1 Mikuls T.R....Gregersen P.K. (2010)
    792. Genome-wide association study meta-analysis identifie s seven new rheumatoid arthritis risk loci. (PubMed id 20453842)1 Stahl E.A....Plenge R.M. (2010)
    793. Different HLA class II (DRB1 and DQB1) alleles determ ine either susceptibility or resistance to NMO and multiple sclerosis among the French Afro-Caribbean population. (PubMed id 20861181)1 Deschamps R....Cabre P. (2010)
    794. Two HLA class I genes independently associated with m ultiple sclerosis. (PubMed id 20678810)1 Link J....Brynedal B. (2010)
    795. Contribution of HLA-DRB1*04 alleles and anti-cyclic c itrullinated antibodies to development of resistance to disease-modifying antir heumatic drugs in early rheumatoid arthritis. (PubMed id 20383728)1 Mori S....Yonemura K. (2010)
    796. Association of immunoglobulin A deficiency and elevat ed thyrotropin-receptor autoantibodies in two Nordic countries. (PubMed id 20977916)1 Jorgensen G.H....Ludviksson B.R. (2010)
    797. Diagnostic value of anti-cyclic citrullinated peptide s and association with HLA-DRB1 shared epitope alleles in African rheumatoid ar thritis patients. (PubMed id 20196860)1 Singwe-Ngandeu M....Gabay C. (2010)
    798. Cytotoxic T lymphocyte antigen-4 Ala17 polymorphism i s a genetic marker of autoimmune adrenal insufficiency: Italian association stu dy and meta-analysis of European studies. (PubMed id 19884265)1 Brozzetti A....Falorni A. (2010)
    799. HLA-DRB1*0102 is associated with TINU syndrome and bi lateral, sudden-onset anterior uveitis but not with interstitial nephritis alon e. (PubMed id 21059595)1 Mackensen F....Rosenbaum J.T. (2010)
    800. HLA has strongest association with IgA nephropathy in genome-wide analysis. (PubMed id 20595679)1 Feehally J....Ratcliffe P.J. (2010)
    801. HLA association with nasopharyngeal carcinoma in sout hern Tunisia. (PubMed id 19714482)1 Makni H....Frikha M. (2010)
    802. Infectious mononucleosis-linked HLA class I single nu cleotide polymorphism is associated with multiple sclerosis. (PubMed id 20736246)1 Jafari N....Hintzen R.Q. (2010)
    803. Relationship of type 1 diabetes to ancestral proporti ons and HLA DR/DQ alleles in a sample of the admixed Cuban population. (PubMed id 20569042)1 Diaz-Horta O....Novoa L. (2010)
    804. Association of HLA-A, -B and -DRB1 genotype with birt hweight and CD34+ cell content: analysis of Korean newborns and their cord bloo d. (PubMed id 20154067)1 Shin S....Roh E.Y. (2010)
    805. An HLA-A*02:01-B*13:01-DRB1*14:01:03 haplotype conser ved in Taiwanese and a possible close relationship between DRB1*14:01:03 and DR B1*14:54. (PubMed id 21040492)1 Yang K.L....Lin P.Y. (2010)
    806. HLA class I and class II polymorphisms in Tunisian Be rbers. (PubMed id 20666704)1 Hajjej A....Hmida S. (2010)
    807. Distribution of KIR genes in the population of unrela ted individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3). (PubMed id 20492596)1 Jindra P....Koza V. (2010)
    808. Tumor Necrosis Factor Polymorphism Affects Transplant ation Outcome in Patients with Myelodysplastic Syndrome but Not in Those with C hronic Myelogenous Leukemia, Independent of the Presence of HLA-DR15. (PubMed id 20541027)1 Newell L.F....Deeg H.J. (2010)
    809. Masking of a cathepsin G cleavage site in vivo contri butes to the proteolytic resistance of major histocompatibility complex class I I molecules. (PubMed id 20331476)1 Burster T....Mellins E.D. (2010)
    810. Clinical profile and HLA-DRB1 genotype of late onset multiple sclerosis in Western Australia. (PubMed id 20580995)1 Qiu W....Kermode A.G. (2010)
    811. Association of HLA-DRB1*0405 with resistance to multi bacillary leprosy in Taiwanese. (PubMed id 20353806)1 Hsieh N.K....Lin M. (2010)
    812. HLA genes in populations of the Aleutian islands. (PubMed id 21417892)1 Rey D....Arnaiz-Villena A. (2010)
    813. Detection of a rare Caucasoid HLA-DRB1*0337 in a Taiw anese bone marrow donor using sequence-based typing method. (PubMed id 19758311)1 Chen M.J....Yang K.L. (2010)
    814. PheWAS: demonstrating the feasibility of a phenome-wi de scan to discover gene-disease associations. (PubMed id 20335276)1 Denny J.C....Crawford D.C. (2010)
    815. Refining the association of MHC with multiple scleros is in African Americans. (PubMed id 20466734)1 McElroy J.P....Gourraud P.A. (2010)
    816. HLA-DRB1*1501 intensifies the impact of IL-6 promoter polymorphism on the susceptibility to multiple sclerosis in an Iranian populat ion. (PubMed id 20685768)1 Shahbazi M....Rashidbaghan A. (2010)
    817. Association analysis about HLA-DRB1, -DQB1 polymorphi sm and auto-antibodies against I+(1)-adrenergic receptors in Chinese patients wi th essential hypertension. (PubMed id 21091360)1 Sun Y....Liao Y. (2010)
    818. Analysis of maternal-offspring HLA compatibility, par ent-of-origin and noninherited effects for HLA-DRB1 in systemic lupus erythemat osus. (PubMed id 20191587)1 Bronson P.G....Barcellos L.F. (2010)
    819. Common risk allele in aromatic antiepileptic-drug ind uced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese. (PubMed id 20235791)1 Hung S.I....Chen Y.T. (2010)
    820. Correlation between genetic HLA class I and II polymo rphisms and anthropological aspects in the Chaouya population from Morocco (Ara bic speaking). (PubMed id 20492599)1 Canossi A....Adorno D. (2010)
    821. HLA polymorphism in three indigenous populations of S abah and Sarawak. (PubMed id 20196825)1 Dhaliwal J.S....Lee Y.Y. (2010)
    822. Genetic and environmental factors and the distributio n of multiple sclerosis in Europe. (PubMed id 20345929)1 Handel A.E....Ramagopalan S.V. (2010)
    823. Immune dysregulation by the rheumatoid arthritis shar ed epitope. (PubMed id 20592276)1 De Almeida D.E....Holoshitz J. (2010)
    824. Human leukocyte antigen alleles and the response to p egylated interferon/ribavirin therapy in chronic hepatitis C patients. (PubMed id 19931565)1 Dai C.Y....Yu M.L. (2010)
    825. Association between HLA-DRB1, HLA-DRQB1 alleles, and CD4(+)CD28 (null) T cells in a Chinese population with coronary heart disease. (PubMed id 20842443)1 Sun W....Huang L. (2010)
    826. HLA-A, -B, -DRB1 allele frequencies and haplotypic as sociation from DNA typing data of 7096 Korean cord blood units. (PubMed id 20196826)1 Yoon J.H....Roh E.Y. (2010)
    827. Evidence for molecular mimicry between human T cell e pitopes in rotavirus and pancreatic islet autoantigens. (PubMed id 20083660)1 Honeyman M.C....Harrison L.C. (2010)
    828. Cancer-associated myositis and anti-p155 autoantibody in a series of 85 patients with idiopathic inflammatory myopathy. (PubMed id 20075704)1 Trallero-AraguA!s E....Vilardell-TarrAcs M. (2010)
    829. Genetic associations in Italian primary sclerosing ch olangitis: heterogeneity across Europe defines a critical role for HLA-C. (PubMed id 20347497)1 Hov J.R....Invernizzi P. (2010)
    830. The beneficial impact of missing KIR ligands and abse nce of donor KIR2DS3 gene on outcome following unrelated hematopoietic SCT for myeloid leukemia in the Chinese population. (PubMed id 20173784)1 Wu G.Q....Huang H. (2010)
    831. Variants within the immunoregulatory CBLB gene are as sociated with multiple sclerosis. (PubMed id 20453840)1 Sanna S....Cucca F. (2010)
    832. Different HLA-DRB1 allele distributions in distinct c linical subgroups of sarcoidosis patients. (PubMed id 20187937)1 Grunewald J....Eklund A. (2010)
    833. Human leukocyte antigen type and progression from ons et of symptoms to development of asthma. (PubMed id 20214848)1 Martyn M.B....Juhn Y.J. (2010)
    834. Allergic women show reduced T helper type 1 allorespo nses to fetal human leucocyte antigen mismatch during pregnancy. (PubMed id 19860744)1 Prescott S.L....Christiansen F.T. (2010)
    835. Distribution of HLA class II alleles and haplotypes i n Mexican Mestizo population: comparison with other populations. (PubMed id 20380523)1 Vargas-AlarcA^n G....Arnaiz-Villena A. (2010)
    836. Human leucocyte antigen class II DRB1 and DQB1 associ ations in human immunodeficiency virus-infected patients of Mumbai, India. (PubMed id 20345872)1 Shankarkumar U....Pazare A. (2010)
    837. Variation within DNA repair pathway genes and risk of multiple sclerosis. (PubMed id 20522537)1 Briggs F.B....Barcellos L.F. (2010)
    838. [Clinical and epidemiological features and HLA associ ation in patients with pars planitis] (PubMed id 20537664)1 Mantrana-Bermejo M.E....SA!nchez-RomA!n J. (2010)
    839. Epistasis between HLA-DRB1 parental alleles in a Span ish cohort with multiple sclerosis. (PubMed id 20810130)1 Romero-Pinel L....Arbizu T. (2010)
    840. Association of killer cell immunoglobulin-like recept ors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diab etes. (PubMed id 20580654)1 Jobim M....Schwartsmann G. (2010)
    841. A functional RANKL polymorphism associated with young er age at onset of rheumatoid arthritis. (PubMed id 20533289)1 Tan W....Tsao B.P. (2010)
    842. The impact of pregnancy on rheumatoid arthritis outco me: the role of maternofetal HLA class II disparity. (PubMed id 20031464)1 Zrour S.H....Bergaoui N. (2010)
    843. Evaluation of the rheumatoid arthritis susceptibility loci HLA-DRB1, PTPN22, OLIG3/TNFAIP3, STAT4 and TRAF1/C5 in an inception cohor t. (PubMed id 20353580)1 Morgan A.W....Emery P. (2010)
    844. Genetic heterogeneity in latent autoimmune diabetes i s linked to various degrees of autoimmune activity: results from the Nord-TrA,nd elag Health Study. (PubMed id 19833889)1 Pettersen E....Grill V. (2010)
    845. Patient HLA-DRB1* and -DQB1* allele and haplotype ass ociation with hepatitis C virus persistence and clearance. (PubMed id 20392899)1 Ali L....Khan K.M. (2010)
    846. IgA deficiency and the MHC: assessment of relative ri sk and microheterogeneity within the HLA A1 B8, DR3 (8.1) haplotype. (PubMed id 19834793)1 Mohammadi J....HammarstrAPm L. (2010)
    847. Polymorphisms in the genes encoding TGF-beta1, TNF-al pha, and IL-6 show association with type 1 diabetes mellitus in the Slovak popu lation. (PubMed id 20686866)1 Javor J....Buc M. (2010)
    848. A polymorphism in the HLA-DPB1 gene is associated wit h susceptibility to multiple sclerosis. (PubMed id 21049023)1 Field J....Stankovich J. (2010)
    849. Peanut-allergic subjects and their peanut-tolerant si blings have large differences in peanut-specific IgG that are independent of HL A class II. (PubMed id 20850383)1 Dreskin S.C....Freed B.M. (2010)
    850. Cutting edge: HLA-DM-mediated peptide exchange functi ons normally on MHC class II-peptide complexes that have been weakened by elimi nation of a conserved hydrogen bond. (PubMed id 20038641)1 Ferrante A. and Gorski J. (2010)
    851. Effect of human leukocyte antigen homozygosity on rub ella vaccine-induced humoral and cell-mediated immune responses. (PubMed id 19896518)1 Kennedy R.B....Poland G.A. (2010)
    852. HLA class II alleles and haplotypes in Lithuanian chi ldren with type 1 diabetes and healthy children (HLA and type 1 diabetes). (PubMed id 20966625)1 SkrodenienA9 E....Ludvigsson J. (2010)
    853. HLA class I and II alleles and haplotypes in ethnic N ortheast Thais. (PubMed id 20230525)1 Romphruk A.V....Leelayuwat C. (2010)
    854. HLA class II, MICA and PRL gene polymorphisms: the co mmon contribution to the systemic lupus erythematosus development in Czech popu lation. (PubMed id 20352225)1 FojtA-kovA! M....CernA! M. (2010)
    855. Association of IFIH1 and other autoimmunity risk alle les with selective IgA deficiency. (PubMed id 20694011)1 Ferreira R.C....HammarstrAPm L. (2010)
    856. Genetic link among Hani, Bulang and other Southeast A sian populations: evidence from HLA -A, -B, -C, -DRB1 genes and haplotypes dist ribution. (PubMed id 20637045)1 Shi L....Chu J.Y. (2010)
    857. A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. (PubMed id 20639878)1 Singer J.B....Paulding C.A. (2010)
    858. The frequency of DRB1*1454 in South German Caucasians . (PubMed id 20210922)1 FA1rst D....Mytilineos J. (2010)
    859. Identification of HLA-DRB1 Alleles Associated with Gr aves' Disease in Koreans by Sequence-Based Typing. (PubMed id 21062236)1 Jang H.W....Chung J.H. (2010)
    860. Association between HLA-B*4001 and lipodystrophy amon g HIV-infected patients from Thailand who received a stavudine-containing antir etroviral regimen. (PubMed id 20073992)1 Wangsomboonsiri W....Sungkanuparph S. (2010)
    861. Analysis of HLA-A, HLA-B and HLA-DRB1 alleles in Chin ese patients with lung cancer. (PubMed id 20449807)1 Yang L....Xu S.F. (2010)
    862. Structural basis for the presentation of tumor-associ ated MHC class II-restricted phosphopeptides to CD4+ T cells. (PubMed id 20417641)1 Li Y....Mariuzza R.A. (2010)
    863. HIV controllers with HLA-DRB1*13 and HLA-DQB1*06 alle les have strong, polyfunctional mucosal CD4+ T-cell responses. (PubMed id 20719952)1 Ferre A.L....Shacklett B.L. (2010)
    864. Preserved MHC class II antigen processing in monocyte s from HIV-infected individuals. (PubMed id 20209134)1 Woc-Colburn L....Canaday D.H. (2010)
    865. Associations of cigarette smoking with rheumatoid art hritis in African Americans. (PubMed id 20722010)1 Mikuls T.R....Bridges S.L. (2010)
    866. Polymorphism of HLA class II genes in Berbers from So uthern Tunisia. (PubMed id 20670354)1 Fadhlaoui-Zid K....Sanchez-Mazas A. (2010)
    867. HLA-DRB1 as a risk factor in children with autoimmune hepatitis and its relation to hepatitis A infection. (PubMed id 21067577)1 Elfaramawy A.A....Aziz H.M. (2010)
    868. Sarcoidosis HLA class II genotyping distinguishes dif ferences of clinical phenotype across ethnic groups. (PubMed id 20685690)1 Sato H....Welsh K.I. (2010)
    869. Association of human leukocyte antigen class II allel es with response to immunosuppressive therapy in Korean aplastic anemia patient s. (PubMed id 19819281)1 Song E.Y....Park M.H. (2010)
    870. Role of HIV-1 Nef protein for virus replication in vit ro. (PubMed id 19770068)1 Jere A....Nomaguchi M. (2010)
    871. Analysis of HLA-DRB1 polymorphisms in Japanese patien ts with primary biliary cirrhosis (PBC): The HLA-DRB1polymorphism determines th e relative risk of antinuclear antibodies for disease progression in PBC. (PubMed id 20374297)1 Nakamura M....Ishibashi H. (2010)
    872. ESTIMATION OF GENETIC RISK FOR TYPE 1 DIABETES MELLIT US IN NEWBORNS ON DRIED BLOOD SPOT. (PubMed id 20101097)1 Giannattasio A....d'Annunzio G. (2010)
    873. Specific human leukocyte antigen class I and II allel es associated with hepatitis C virus viremia. (PubMed id 20169624)1 Kuniholm M.H....Carrington M. (2010)
    874. A shared HLA-DRB1 epitope in the DR beta first domain is associated with Vogt-Koyanagi-Harada syndrome in Indian patients. (PubMed id 20216938)1 Tiercy J.M....Baglivo E. (2010)
    875. Multiple sclerosis risk markers in HLA-DRA, HLA-C, an d IFNG genes are associated with sex-specific childhood leukemia risk. (PubMed id 21067287)1 Morrison B.A....Dorak M.T. (2010)
    876. Number of autoantibodies and HLA genotype, more than high titers of glutamic acid decarboxylase autoantibodies, predict insulin depe ndence in latent autoimmune diabetes of adults. (PubMed id 20603341)1 Maioli M....Cucca F. (2010)
    877. No evidence for an effect of DNA methylation on multi ple sclerosis severity at HLA-DRB1*15 or HLA-DRB5. (PubMed id 20394989)1 Handel A.E....Ramagopalan S.V. (2010)
    878. Influence of HLA-DRB1 alleles on the susceptibility a nd resistance to multiple sclerosis in Japanese patients with respect to anti-a quaporin 4 antibody status. (PubMed id 20028711)1 Isobe N....Kira J. (2010)
    879. HLA-DRB1*11: a strong risk factor for acquired severe ADAMTS13 deficiency-related idiopathic thrombotic thrombocytopenic purpura in Caucasians. (PubMed id 20141578)1 Coppo P....Loiseau P. (2010)
    880. MSH5 is not a genetic predisposing factor for immunog lobulin A deficiency but marks the HLA-DRB1*0102 subgroup carrying susceptibili ty. (PubMed id 20542071)1 Pozo N.D....NA_A+ez C. (2010)
    881. Nonmyeloablative HLA-haploidentical bone marrow trans plantation with high-dose posttransplantation cyclophosphamide: effect of HLA d isparity on outcome. (PubMed id 19925877)1 Kasamon Y.L....Fuchs E.J. (2010)
    882. Association between HLA-DRB1 alleles polymorphism and hepatocellular carcinoma: a meta-analysis. (PubMed id 21172035)1 Lin Z.H....Xuan S.Y. (2010)
    883. HLA-A, -B, -DRB1 alleles and haplotypes frequencies i n Moroccan patients with leukemia. (PubMed id 20478772)1 Kabbaj M....Hassar M. (2010)
    884. CIITA variation in the presence of HLA-DRB1*1501 incr eases risk for multiple sclerosis. (PubMed id 20211854)1 Bronson P.G....Haines J.L. (2010)
    885. Effect of HLA class I and class II alleles on progres sion from autoantibody positivity to overt type 1 diabetes in children with ris k-associated class II genotypes. (PubMed id 20739684)1 Lipponen K....Ilonen J. (2010)
    886. HLA and KIR frequencies in Sicilian Centenarians. (PubMed id 20426625)1 ListA- F....Candore G. (2010)
    887. HLA alleles and haplotypes distribution in Dai popula tion in Yunnan province, Southwest China. (PubMed id 20003137)1 Shi L....Tokunaga K. (2010)
    888. HLA polymorphisms and detection of kaposi sarcoma-ass ociated herpesvirus DNA in saliva and peripheral blood among children and their mothers in the uganda sickle cell anemia KSHV Study. (PubMed id 21087485)1 Guech-Ongey M....Mbulaiteye S.M. (2010)
    889. Human leukocyte antigen-DR15, low infant sibling expo sure and multiple sclerosis: gene-environment interaction. (PubMed id 20225292)1 van der Mei I.A....Dwyer T. (2010)
    890. Diverging effects of HLA-DPB1 matching status on outc ome following unrelated donor transplantation depending on disease stage and th e degree of matching for other HLA alleles. (PubMed id 19924143)1 Shaw B.E....Madrigal J.A. (2010)
    891. Human leukocyte antigen-A, -B, and -DRB1 allele and h aplotype frequencies in the Mozambican population: a blood donor-based populati on study. (PubMed id 20600444)1 Assane A.A....Porto L.C. (2010)
    892. Presence of CSF oligoclonal bands (OCB) is associated with the HLA-DRB1 genotype in a West Australian multiple sclerosis cohort. (PubMed id 19879597)1 Wu J.S....Kermode A.G. (2010)
    893. Genome-wide association study identifies new HLA clas s II haplotypes strongly protective against narcolepsy. (PubMed id 20711174)1 Hor H....Tafti M. (2010)
    894. Visual hallucinations and HLA class II antigens in co rtical dementia. (PubMed id 20606439)1 GA^mez-Tortosa E....CA!rdaba B. (2010)
    895. HLA-DRB1*1501 tagging rs3135388 polymorphism is not a ssociated with neuromyelitis optica. (PubMed id 20591987)1 Matiello M....Weinshenker B.G. (2010)
    896. Influence of female hormonal factors, in relation to autoantibodies and genetic markers, on the development of rheumatoid arthritis in northern Sweden: a case-control study. (PubMed id 20560812)1 Berglin E....RantapAoAo Dahlqvist S. (2010)
    897. Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis. (PubMed id 21072187)1 Laukens D....De Vos M. (2010)
    898. HLA-DR association in papillary thyroid carcinoma. (PubMed id 20164547)1 Amoli M.M....Bazzaz J.T. (2010)
    899. Common vaccinations among adults do not increase the risk of developing rheumatoid arthritis: results from the Swedish EIRA study. (PubMed id 20603497)1 Bengtsson C....Alfredsson L. (2010)
    900. Allele polymorphism and haplotype diversity of HLA-A, -B and -DRB1 loci in sequence-based typing for Chinese Uyghur ethnic group. (PubMed id 21079793)1 Shen C.M....Zhang J.J. (2010)
    901. Anthropological analysis of Koreans using HLA class I I diversity among East Asians. (PubMed id 20522202)1 Yang J.H....Oh H.B. (2010)
    902. Major histocompatibility complex (MHC) class II allel es, haplotypes and epitopes which confer susceptibility or protection in system ic sclerosis: analyses in 1300 Caucasian, African-American and Hispanic cases a nd 1000 controls. (PubMed id 19596691)1 Arnett F.C....Reveille J.D. (2010)
    903. HLA class II polymorphism in Latin American patients with multiple sclerosis. (PubMed id 19896562)1 Rojas O.L....Anaya J.M. (2010)
    904. HLA-DRB1*15, low infant sibling exposure, and multipl e sclerosis gene-environment interaction. (PubMed id 20437569)1 Ramagopalan S.V....Ebers G.C. (2010)
    905. Dissection of the FCGR3A association with RA: increas ed association in men and with autoantibody positive disease. (PubMed id 19700393)1 Robinson J.I....Taylor J.C. (2010)
    906. Human leukocyte antigen (HLA) A1-B8-DR3 (8.1) haploty pe, tumor necrosis factor (TNF) G-308A, and risk of non-Hodgkin lymphoma. (PubMed id 20147981)1 Abdou A.M....Wang S.S. (2010)
    907. HLA-DRB1*03 and DRB1*04 are associated with atrophic gastritis in an Italian population. (PubMed id 20627832)1 Lahner E....Annibale B. (2010)
    908. HLA polymorphisms in Sindhi community in Mumbai, Indi a. (PubMed id 20518846)1 Chhaya S....Saranath D. (2010)
    909. Genetic variants in the prediction of rheumatoid arth ritis. (PubMed id 20439292)1 van der Helm-van Mil A.H....Huizinga T.W. (2010)
    910. Association of human leukocyte antigen class II allel es with pemphigus vulgaris in a Turkish population. (PubMed id 20507388)1 Tunca M....Akar A. (2010)
    911. HLA-DRB1*01 allele and low plasma immunoglobulin G1 c oncentration may predispose to herpes-associated recurrent lymphocytic meningit is. (PubMed id 19879913)1 Kallio-Laine K....Lokki M.L. (2010)
    912. Major histocompatibility complex class II transactiva tor gene polymorphism: associations with LAPfgren's syndrome. (PubMed id 20230522)1 Grunewald J....Padyukov L. (2010)
    913. Polymorphism located in TCRA locus confers susceptibi lity to essential hypersomnia with HLA-DRB1*1501-DQB1*0602 haplotype. (PubMed id 19927159)1 Miyagawa T....Tokunaga K. (2010)
    914. Juvenile idiopathic arthritis and HLA class I and cla ss II interaction and age of onset effects. (PubMed id 20191588)1 Glass D.N. (2010)
    915. Association of IL-4RA single nucleotide polymorphisms , HLA-DR and HLA-DQ in children with Alternaria-sensitive moderate-severe asthm a. (PubMed id 20298583)1 Knutsen A.P....Shah M.R. (2010)
    916. Prediction of radiographic progression in rheumatoid arthritis and the role of antibodies against mutated citrullinated vimentin: re sults from a 10-year prospective study. (PubMed id 19648126)1 Syversen S.W....Kvien T.K. (2010)
    917. Human leukocyte antigen-A, -B, -C, -DRB1 allele and h aplotype frequencies in Americans originating from southern Europe: Contrasting patterns of population differentiation between Italian and Spanish Americans. (PubMed id 20974205)1 Mack S.J....Katovich Hurley C. (2010)
    918. Association of IL4R single-nucleotide polymorphisms w ith rheumatoid nodules in African Americans with rheumatoid arthritis. (PubMed id 20444266)1 Burgos P.I....Bridges S.L. (2010)
    919. HLA status in patients with chronic spontaneous urtic aria. (PubMed id 20559009)1 Bozek A....Jarzab J. (2010)
    920. Genetic aspect of venom allergy: association with HLA class I and class II antigens. (PubMed id 20684489)1 Karakis G.P....Misirligil Z. (2010)
    921. Role of major histocompatibility complex and ethnicit y in acute renal graft rejection. (PubMed id 20692483)1 Torres-Machorro A....Granados J. (2010)
    922. Characterization of tumor necrosis factor-I+ block hap lotypes associated with susceptibility to chronic venous leg ulcers in Caucasia n patients. (PubMed id 20854863)1 Tan J.H....Wallace H.J. (2010)
    923. Polymorphic major histocompatibility complex class II Alu insertions at five loci and their association with HLA-DRB1 and -DQB1 in J apanese and Caucasians. (PubMed id 20403137)1 Kulski J.K....Inoko H. (2010)
    924. The conundrum of HLA-DRB1*14:01/*14:54 and HLA-DRB3*0 2:01/*02:02 mismatches in unrelated hematopoietic SCT. (PubMed id 20972469)1 Pasi A....Martinetti M. (2010)
    925. Correlation of molecular human leukocyte antigen typi ng and outcome in high-risk melanoma patients receiving adjuvant interferon. (PubMed id 20549830)1 Gogas H....Spyropoulou-Vlachou M. (2010)
    926. The impact of anti-HY responses on outcome in current and subsequent pregnancies of patients with recurrent pregnancy losses. (PubMed id 20307907)1 Christiansen O.B....Nielsen H.S. (2010)
    927. HLA class II alleles: susceptibility or resistance to cystic echinococcosis in Yemeni patients. (PubMed id 20424860)1 Al-Ghoury A.B....Rayan H.Z. (2010)
    928. [An evaluation of HLA class 2 alleles and anti-islet antibodies as evidence for non-autoimmune diabetes in Wolfram syndrome]. (PubMed id 21447263)1 ZmysA8owska A....MA8ynarski W. (2010)
    929. Anti-CCP antibodies are associated with early age at onset in patients with rheumatoid arthritis. (PubMed id 20888281)1 Diaz F.J....Anaya J.M. (2010)
    930. [Associations of human leukocyte antigen-A, B, DRB1 g enes with leukemia patients in Anhui province of China]. (PubMed id 20723328)1 Liao Y.Q....Wang B.L. (2010)
    931. Genetic markers in acquired haemophilia. (PubMed id 20586801)1 Oldenburg J....Pavlova A. (2010)
    932. The Severity of Acute Puumala Hantavirus Infection Do es Not Predict the Long-Term Outcome of Patients. (PubMed id 20502044)1 Miettinen M.H....Mustonen J.T. (2010)
    933. Human leukocyte antigen typing in tuberculous rheumat ism: Poncet's disease. (PubMed id 20550778)1 Lugo-Zamudio G.E....Granados J. (2010)
    934. An assessment of the association between childhood as thma and HLA DRB1*03 using extended haplotype analysis. (PubMed id 20735759)1 Hanchard N.A....Juhn Y.J. (2010)
    935. HLA-DRB1: genetic susceptibility and disability progr ession in a Spanish multiple sclerosis population. (PubMed id 20629714)1 Romero-Pinel L....Arbizu T. (2010)
    936. HLA-DRB1*0407 and *1304 are risk factors for sclerode rma renal crisis. (PubMed id 20981823)1 Nguyen B....Assassi S. (2010)
    937. HLA-DRB1 allele heterogeneity influences multiple scl erosis severity as well as risk in Western Australia. (PubMed id 20006387)1 Wu J.S....Kermode A.G. (2010)
    938. HLA polymorphism in a Guarani-Indian population from Paraguay and its usefulness for the Hispano-Indian admixture study in Paraguay. (PubMed id 20670332)1 Benitez O....Loiseau P. (2010)
    939. Influence of HLA DRB1 alleles in the susceptibility o f rheumatoid arthritis and the regulation of antibodies against citrullinated p roteins and rheumatoid factor. (PubMed id 20370905)1 Balsa A....Pascual-Salcedo D. (2010)
    940. HLA-DRB association in neuromyelitis optica is differ ent from that observed in multiple sclerosis. (PubMed id 19995845)1 Brum D.G....Donadi E.A. (2010)
    941. MHC variation and risk of childhood B-cell precursor acute lymphoblastic leukaemia. (PubMed id 21059899)1 Hosking F.J....Houlston R.S. (2010)
    942. Autoimmune hepatitis, HLA and extended haplotypes. (PubMed id 20933106)1 Oliveira L.C....Goldberg A.C. (2010)
    943. Association of HLA-DRB1 alleles with keloids in Chine se Han individuals. (PubMed id 20522201)1 Lu W.S....Yang S. (2010)
    944. Shared molecular amino acid signature in the HLA-DR p eptide binding pocket predisposes to both autoimmune diabetes and thyroiditis. (PubMed id 20837527)1 Menconi F....Tomer Y. (2010)
    945. Human risk allele HLA-DRB1*0405 predisposes class II transgenic Ab0 NOD mice to autoimmune pancreatitis. (PubMed id 20303356)1 Freitag T.L....nderstrup G. (2010)
    946. Human leukocyte antigen association in idiopathic thr ombotic thrombocytopenic purpura: evidence for an immunogenetic link. (PubMed id 19922436)1 Scully M....Machin S. (2010)
    947. Impact of amino acid substitution at residue 9 of HLA -A2 on the development of acute GVHD in Korean pediatric patients receiving unr elated hematopoietic stem cell transplantation. (PubMed id 20536911)1 Hwang S.H....Lee E.Y. (2010)
    948. Clinical and immunological differences between early and late-onset myasthenia gravis in Japan. (PubMed id 21074862)1 Suzuki S....Suzuki N. (2010)
    949. Association of HLA-DRB1* and keloid disease in an Afr o-Caribbean population. (PubMed id 19874322)1 Brown J.J....Bayat A. (2010)
    950. Influence of HLA-DRB1 allele heterogeneity on disease risk and clinical course in a West Australian MS cohort: a high-resolution gen otyping study. (PubMed id 20207784)1 Wu J.S....Kermode A.G. (2010)
    951. Hormonal replacement therapy may reduce the risk for RA in women with early arthritis who carry HLA-DRB1 *01 and/or *04 alleles by p rotecting against the production of anti-CCP: results from the ESPOIR cohort. (PubMed id 19740903)1 Salliot C....Dougados M. (2010)
    952. Opposing effects of the HLA-DRB1*0301-DQB1*0201 haplo type on the risk for multiple sclerosis in diverse Arab populations in Israel. (PubMed id 20463743)1 Benedek G....Miller A. (2010)
    953. Molecular identification of the HLA-DRB1-DQB1 for dia gnosis and follow-up of acute leukemias. (PubMed id 20051322)1 Fernandes T.A....Kraemer M.H. (2010)
    954. Human leukocyte antigen (HLA) and single nucleotide p olymorphisms (SNPs) tumor necrosis factor (TNF)-alpha -238 and -308 as genetic markers of susceptibility to psoriasis and severity of the disease in a long-te rm follow-up Brazilian study. (PubMed id 20931685)1 MagalhALes R.F....Kraemer M.H. (2010)
    955. HLA DR-DQ combination associated with the increased r isk of developing human HCV positive non-Hodgkin's lymphoma is related to the t ype II mixed cryoglobulinemia. (PubMed id 20002609)1 De Re V....Toffoli G. (2010)
    956. MHC class II-associated proteins in B-cell exosomes a nd potential functional implications for exosome biogenesis. (PubMed id 20458337)1 Buschow S.I....Stoorvogel W. (2010)
    957. Human leukocyte antigens and HIV type 1 viral load in early and chronic infection: predominance of evolving relationships. (PubMed id 20224785)1 Tang J....Kaslow R.A. (2010)
    958. Genetic and diabetic auto-antibody markers in Saudi c hildren with type 1 diabetes. (PubMed id 20858521)1 Manan H....Sitelbanat A. (2010)
    959. Contribution of anti-CCP antibodies, proximal interph alangeal joint involvement, HLA-DRB1 shared epitope, and PADI4 as risk factors for the development of rheumatoid arthritis in palindromic rheumatism. (PubMed id 20476860)1 Tamai M....Eguchi K. (2010)
    960. Characterization of D6S2806 and D6S2879 short tandem repeat loci in HLA-DRB1 region in Iranian population. (PubMed id 20403136)1 Vallian S....Hojati Z. (2010)
    961. Peptidyl arginine deiminase type IV (PADI4) haplotype s interact with shared epitope regardless of anti-cyclic citrullinated peptide antibody or erosive joint status in rheumatoid arthritis: a case control study. (PubMed id 20537173)1 Bang S.Y....Kang C. (2010)
    962. Association of HLA haplotypes with paroxysmal nocturn al hemoglobinuria. (PubMed id 20970669)1 Nowak J....Zupanska B. (2010)
    963. Modifying effects of HLA-DRB1 allele interactions on age at onset of multiple sclerosis in Western Australia. (PubMed id 19995849)1 Wu J.S....Kermode A.G. (2010)
    964. Smoking increases rheumatoid arthritis susceptibility in individuals carrying the HLA-DRB1 shared epitope, regardless of rheumatoid factor or anti-cyclic citrullinated peptide antibody status. (PubMed id 20112396)1 Bang S.Y....Bae S.C. (2010)
    965. [HLA-DRB1 allelic polymorphism in children with juven ile idiopathic arthritis] (PubMed id 20497637)1 Wu J. and Zeng H.S. (2010)
    966. Does pregnancy provide vaccine-like protection agains t rheumatoid arthritis? (PubMed id 20309863)1 Guthrie K.A....Nelson J.L. (2010)
    967. Association of specific amino acid sequence (QRRAA) o f HLA-DRB1*0405 with rheumatoid arthritis in a Tunisian population. (PubMed id 21598828)1 Dhaouadi T....Lakhoua-Gorgi Y. (2010)
    968. Type 1 diabetes and LADA--occurrence of HLA-DRB1 *03 and DRB1 *04 alleles in two age different groups of diabetics. (PubMed id 21033293)1 Weber P....Cerna M. (2010)
    969. HLA Class I and II profiles in SALo Miguel Island (Azo res): genetic diversity and linkage disequilibrium. (PubMed id 20462405)1 Pacheco P.R....Mota-Vieira L. (2010)
    970. Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respirato ry papillomatosis. (PubMed id 19861144)1 Bonagura V.R....Rajalingam R. (2010)
    971. Distribution of human leukocyte antigen alleles and h aplotypes in Oroqen and Ewenki nationality minority in Inner Mongolia Autonomou s Region of China. (PubMed id 20518845)1 Zhang H.B....Lai J.H. (2010)
    972. Effect of human leukocyte antigen class II genes on a cute-onset and slow-onset type 1 diabetes in the Japanese population. (PubMed id 20510319)1 Katahira M....Yasuda Y. (2010)
    973. Association of HLA Class II alleles and haplotypes wi th cervical dystonia: HLA DR13-DQ6 (DQB1*0604) homozygotes are at greatly incre ased risk of cervical dystonia in Caucasian Americans. (PubMed id 20843162)1 Deitiker P.R....Atassi M.Z. (2010)
    974. HLA-DRB1*0901 lowers anti-cyclic citrullinated peptid e antibody levels in Japanese patients with rheumatoid arthritis. (PubMed id 19854714)1 Okada Y....Yamamoto K. (2010)
    975. HLA-DQ2(+) individuals are susceptible to Hu-Ab assoc iated paraneoplastic neurological syndromes. (PubMed id 20547426)1 de Graaf M.T....Smitt P.A. (2010)
    976. Genetic variants of CC chemokine genes in experimenta l autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis. (PubMed id 19865101)1 Ockinger J....Olsson T. (2010)
    977. HLA genotyping in the international Type 1 Diabetes G enetics Consortium. (PubMed id 20595243)1 Mychaleckyj J.C....Erlich H.A. (2010)
    978. Adult Patients with Eosinophilic Esophagitis Do Not S how an Increased Frequency of the HLA-DQ2/DQ8 Genotypes Predisposing to Celiac Disease. (PubMed id 20725783)1 Lucendo A.J....Rodrigo L. (2010)
    979. HLA Class I and Class II HLA DRB Profiles in Egyptian Children with Rheumatic Valvular Disease. (PubMed id 20145915)1 El-Hagrassy N....Joseph N. (2010)
    980. Low level of systemic autoimmunity in Western Austral ian multiple sclerosis patients. (PubMed id 20150397)1 Wei Qiu ....Kermode A.G. (2010)
    981. Capture of type 1 diabetes-susceptible HLA DR-DQ hapl otypes in Japanese subjects using a tag single nucleotide polymorphism. (PubMed id 19837788)1 Nakanishi K. and Shima Y. (2010)
    982. Absence of consistent association between human leuko cyte antigen-I and -II alleles and human T-lymphotropic virus type 1 (HTLV-1)-a ssociated myelopathy/tropical spastic paraparesis risk in an HTLV-1 French Afro -Caribbean population. (PubMed id 20851016)1 Deschamps R....Olindo S. (2010)
    983. Genotyping HLA-DRB1 and HLA-DQB1 alleles in Japanese patients with normal tension glaucoma. (PubMed id 21031025)1 Suzuki M....Mizuki N. (2010)
    984. Immunoglobulin IgG Fc-receptor polymorphisms and HLA class II molecules in Guillain-BarrAc syndrome. (PubMed id 20105138)1 Sinha S....Agrawal S. (2010)
    985. Evidence for interaction between 5-hydroxytryptamine (serotonin) receptor 2A and MHC type II molecules in the development of rheumat oid arthritis. (PubMed id 20179740)1 Seddighzadeh M....Padyukov L. (2010)
    986. Therapeutic immunization with HIV-1 Tat reduces immune activation and loss of regulatory T-cells and improves immune function in subje cts on HAART. (PubMed id 21085635)1 Ensoli B....Garaci E. (2010)
    987. Association of HLA-A, -B, and -DRB1 with pulmonary tu berculosis in western Javanese Indonesia. (PubMed id 20438789)1 Yuliwulandari R....Tokunaga K. (2010)
    988. Human leukocyte antigen class I and II alleles in non -Hodgkin lymphoma etiology. (PubMed id 20385791)1 Wang S.S....Carrington M. (2010)
    989. The impact of HLA-DRB alleles on the subclass titres of antibodies against citrullinated peptides. (PubMed id 20584722)1 Engelmann R....Mueller-Hilke B. (2010)
    990. HLA-DRB1*15 confers susceptibility to juvenile SLE bu t is not associated with disease presentation: an Egyptian Study. (PubMed id 20380521)1 Mosaad Y.M....Elhanbly S. (2010)
    991. A regulatory variant in CCR6 is associated with rheum atoid arthritis susceptibility. (PubMed id 20453841)1 Kochi Y....Yamamoto K. (2010)
    992. Genetic variants of STAT4 associated with rheumatoid arthritis in persons of Asian and European ancestry do not replicate in African Americans. (PubMed id 20237121)1 Kelley J.M....Bridges S.L. (2010)
    993. HLA class I and genetic susceptibility to type 1 diab etes: results from the Type 1 Diabetes Genetics Consortium. (PubMed id 20798335)1 Noble J.A....Erlich H.A. (2010)
    994. Distribution of HLA-DRB1 alleles in Argentinean patie nts with Chagas' disease cardiomyopathy. (PubMed id 19811437)1 GarcA-a BorrA!s S....Racca A. (2009)
    995. HLA-DRB1 and -DQB1 loci in three west African ethnic groups: genetic relationship with sub-Saharan African and European populations. (PubMed id 19664674)1 Lulli P....Modiano D. (2009)
    996. High-density SNP screening of the major histocompatib ility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1 Barcellos L.F....Criswell L.A. (2009)
    997. HLA-DPB1 and NFKBIL1 may confer the susceptibility to chronic thromboembolic pulmonary hypertension in the absence of deep vein thrombosis. (PubMed id 19165231)1 Kominami S....Kimura A. (2009)
    998. HLA class II alleles in patients with multiple sclero sis in the Biscay province (Basque Country, Spain). (PubMed id 19585166)1 FernA!ndez O....Leyva L. (2009)
    999. [Association study between HLA-DRB genes and asthmati c children] (PubMed id 20095337)1 Zhao J....Qiu C.C. (2009)
    1000. Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex. (PubMed id 19098025)1 Chao M.J....Ebers G.C. (2009)
    1001. HLA haplotypes and birth weight variation: is your fu ture going to be light or heavy? (PubMed id 19500315)1 Capittini C....Cuccia M. (2009)
    1002. [Frequencies of the DRB1, DQA1, DQB1 and TNFA alleles in immigrant population of West Siberia] (PubMed id 19769302)1 Golovanova O.V....Smol'nikova M.V. (2009)
    1003. Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci. (PubMed id 19116923)1 Vignal C....Wilson A.G. (2009)
    1004. Human leukocyte antigen-DRB1 and -DQB1 genotyping in lupus patients with and without antiphospholipid syndrome. (PubMed id 19758197)1 Kapitany A....Kiss E. (2009)
    1005. Allelic distribution and the effect of haplotype combination for HLA type II loci in the celiac disease population of the Valencian community (Spain). (PubMed id 19254257)1 Donat E....Ribes-Koninckx C. (2009)
    1006. Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D. (PubMed id 19197344)1 Ramagopalan S.V....Knight J.C. (2009)
    1007. Influence of Common and Specific HLA-DRB1/DQB1 Haplotypes on Genetic Susceptibilities of Three Distinct Arab Populations to Type 1 Diabetes. (PubMed id 19005023)1 Stayoussef M....Almawi W.Y. (2009)
    1008. Effects of mismatching for minor histocompatibility a ntigens on clinical outcomes in HLA-matched, unrelated hematopoietic stem cell transplants. (PubMed id 19539218)1 Spellman S....Ellis T.M. (2009)
    1009. The gene founder effect of two spontaneous mutations in ethnic Chinese (Taiwanese) CAH patients with 21-hydroxylase deficiency. (PubMed id 19201236)1 Lee Y.J....Lee H.H. (2009)
    1010. Molecular analysis of HLA-DRB1 allelic associations w ith systemic lupus erythematous and lupus nephritis in Taiwan. (PubMed id 19502265)1 Pan C.F....Lee Y.J. (2009)
    1011. A common variant in DRD3 receptor is associated with autism spectrum disorder. (PubMed id 19058789)1 de Krom M....van Ree J.M. (2009)
    1012. High-resolution HLA matching in double-umbilical-cord-blood reduced-intensity transplantation in adults. (PubMed id 19159415)1 Delaney M....Ballen K.K. (2009)
    1013. Study on association between polymorphism of HLA-DRB1 alleles and BehAset's disease. (PubMed id 20205319)1 Shang Y.B....Chen H.D. (2009)
    1014. Human leukocyte antigen profile in HIV-1 infected ind ividuals and AIDS patients from Chongqing, China. (PubMed id 19703245)1 Huang X....Xiong H. (2009)
    1015. The HLA Alleles DRB1*13 and DQB1*06 Are Associated to Whipple's Disease. (PubMed id 19208355)1 Martinetti M....Corazza G.R. (2009)
    1016. Prediction of duration and success rate of unrelated hematopoietic stem cell donor searches based on the patient's HLA-DRB1 allele and DRB1-DQB1 haplotype frequencies. (PubMed id 19290000)1 Hirv K....Mytilineos J. (2009)
    1017. Differential association of HLA with three subtypes o f type 1 diabetes: fulminant, slowly progressive and acute-onset. (PubMed id 19812988)1 Kawabata Y....Makino H. (2009)
    1018. MHC class I and class II genes in Tunisian patients w ith reactive and undifferentiated arthritis. (PubMed id 19473559)1 Siala M....Makni H. (2009)
    1019. HLA-DR, -DQB typing of steroid-sensitive idiopathic nephrotic syndrome children in Taiwan. (PubMed id 19390203)1 Huang Y.Y....Lan J.L. (2009)
    1020. Immunogenetic susceptibility to diabetes mellitus in patients with liver disease. (PubMed id 19663932)1 Montano-Loza A.J....Mason A.L. (2009)
    1021. Association of polymorphism in genes encoding kappaB inhibitors (IkappaB) with susceptibility to and phenotype of Graves' disease: a case-control study. (PubMed id 19886988)1 Kurylowicz A....Bednarczuk T. (2009)
    1022. An extension to a statistical approach for family based association studies provides insights into genetic risk factors for multiple sclerosis in the HLA-DRB1 gene. (PubMed id 19193207)1 Ramagopalan S.V....Wittkowski K.M. (2009)
    1023. Cutting edge: permissive MHC class II allele changes the pattern of antitumor immune response resulting in failure of tumor rejection. (PubMed id 19155468)1 Klyushnenkova E.N....Alexander R.B. (2009)
    1024. Interactions of viral protein U (Vpu) with cellular fa ctors. (PubMed id 20012522)1 Guatelli J.C. (2009)
    1025. Genotype and phenotype correlations in diabetic patie nts in Uruguay. (PubMed id 19937591)1 Mimbacas A....Javiel G. (2009)
    1026. Multiple sclerosis risk: interaction between human le ukocyte antigen and the environment in Sardinian population. (PubMed id 19625333)1 Cocco E....Marrosu M.G. (2009)
    1027. Genetic susceptibility to haemorrhagic fever with ren al syndrome caused by Hantaan virus in Chinese Han population. (PubMed id 19473214)1 Wang M.L....Jin B.Q. (2009)
    1028. Prominent brainstem and cerebellar involvement in mul tiple sclerosis with psoriasis. (PubMed id 19482865)1 Ganesvaran G....Pender M.P. (2009)
    1029. Association of human leukocyte antigen class II allel es with severe acute respiratory syndrome in the Vietnamese population. (PubMed id 19445991)1 Keicho N....Quy T. (2009)
    1030. Genetic polymorphism at codon 129 of the prion protein gene is not associated with multiple sclerosis. (PubMed id 19204171)1 StA1ve O....Oksenberg J.R. (2009)
    1031. A regulatory SNP at position -899 in CDKN1A is associated with systemic lupus erythematosus and lupus nephritis. (PubMed id 19262578)1 Kim K....Bae S.C. (2009)
    1032. HLA-DR-DQ haplotypes and type 1 diabetes in Macedonia. (PubMed id 19332095)1 Ilonen J....Knip M. (2009)
    1033. Immunoregulatory effects of HIV-1 Nef protein. (PubMed id 19449444)1 Quaranta M.G....Viora M. (2009)
    1034. HLA risk markers for chronic myelogenous leukemia in Eastern Canada. (PubMed id 19235017)1 Naugler C. and Liwski R. (2009)
    1035. LAPfgren's syndrome: human leukocyte antigen strongly influences the disease course. (PubMed id 18996998)1 Grunewald J. and Eklund A. (2009)
    1036. Risk for intentional violent death associated with HL A genotypes: a preliminary survey of deceased American organ donors. (PubMed id 19495996)1 Hollar D.W. (2009)
    1037. The DERAA HLA-DR alleles in patients with early polyarthritis: protection against severe disease and lack of association with rheumatoid arthritis autoantibodies. (PubMed id 19248090)1 Carrier N....Boire G. (2009)
    1038. Non-inherited maternal human leukocyte antigen alleles in susceptibility to familial rheumatoid arthritis. (PubMed id 18684745)1 Guthrie K.A....Nelson J.L. (2009)
    1039. Analysis of maternal-offspring HLA compatibility, parent-of-origin and non-inherited maternal effects for the classical HLA loci in type 1 diabetes. (PubMed id 19143818)1 Bronson P.G....Barcellos L.F. (2009)
    1040. Race differences in immunogenetic features and photos ensitivity of cutaneous lupus erythematosus from the aspect of Japanese studies . (PubMed id 19758198)1 Furukawa F....Muto M. (2009)
    1041. A functional haplotype of PADI4 gene in rheumatoid arthritis: positive correlation in a French population. (PubMed id 19332633)1 Gandjbakhch F....Solau-Gervais E. (2009)
    1042. HLA haplotype and supertype associations with cellular immune responses and cytokine production in healthy children after rubella vaccine. (PubMed id 19200828)1 Ovsyannikova I.G....Poland G.A. (2009)
    1043. Evidence for an association of HLA-DRB1*15 and DRB1*0 9 with leprosy and the impact of DRB1*09 on disease onset in a Chinese Han popu lation. (PubMed id 20003324)1 Zhang F....Liu J. (2009)
    1044. HLA class I and II polymorphisms in Mexican Mestizo p atients with dengue fever. (PubMed id 19653987)1 FalcA^n-Lezama J.A....Vargas-AlarcA^n G. (2009)
    1045. Confirmation of the novel association at the BTNL2 lo cus with ulcerative colitis. (PubMed id 19659809)1 Pathan S....Jewell D.P. (2009)
    1046. Clinical and immunogenetic prognostic factors for rad iographic severity in ankylosing spondylitis. (PubMed id 19565552)1 Ward M.M....Weisman M.H. (2009)
    1047. Autoantibodies to a 140-kd protein in juvenile dermat omyositis are associated with calcinosis. (PubMed id 19479859)1 Gunawardena H....McHugh N.J. (2009)
    1048. A novel HLA-DRB1 allele, DRB*1611, is identified in two Taiwanese individuals. (PubMed id 19500310)2 Chu C.-C.... Lin M. (2009)
    1049. Relatedness and HLA-DRB1 typing may discriminate the magnitude of the genetic susceptibility to tuberculosis using a household conta ct model. (PubMed id 19692729)1 Lucena-Silva N....de Albuquerque M.D. (2009)
    1050. HLA-DRB1 and month of birth in multiple sclerosis. (PubMed id 20018638)1 Ramagopalan S.V....Ebers G.C. (2009)
    1051. HLA-E gene polymorphism associated with susceptibility to Kawasaki disease and formation of coronary artery aneurysms. (PubMed id 19180512)1 Lin Y.J....Tsai F.J. (2009)
    1052. Haplotype analysis of HLA-A, -B antigens and -DRB1 alleles in south Indian HIV-1-infected patients with and without pulmonary tuberculosis. (PubMed id 19392836)1 Raghavan S....Narayanan P.R. (2009)
    1053. Major histocompatibility complex class II (DRB1*, DQA1*, and DQB1*) and DRB1*04 subtypes' associations of Hashimoto's thyroiditis in a Greek population. (PubMed id 19254248)1 Kokaraki G....Yovos J.G. (2009)
    1054. Ethnic and geographical differences in HLA associations with the outcome of hepatitis C virus infection. (PubMed id 19409091)1 Wang J.H....Rong L. (2009)
    1055. Impact of polymorphisms of the major histocompatibili ty complex class II, interleukin-10, tumor necrosis factor-alpha and cytotoxic T-lymphocyte antigen-4 genes on inhibitor development in severe hemophilia A. (PubMed id 19817985)1 Pavlova A....Oldenburg J. (2009)
    1056. Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region. (PubMed id 19116921)1 Ding B....Klareskog L. (2009)
    1057. Reevaluation of the interaction between HLA-DRB1 shar ed epitope alleles, PTPN22, and smoking in determining susceptibility to autoan tibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Ca ucasian population. (PubMed id 19714585)1 Morgan A.W....Martin S.G. (2009)
    1058. Human leukocyte antigens I and II haplotypes associat ed with human papillomavirus 16-positive invasive cervical cancer in Mexican wo men. (PubMed id 19820376)1 HernA!ndez-HernA!ndez D.M....Mohar-Betancourt A. (2009)
    1059. [A 1:2 matched case-control study on the interaction of HPV16E6 and HLA-DR9 allele to esophageal cancer in Kazakh ethnicity, Xinjian g] (PubMed id 20193235)1 Liao P.H....He L. (2009)
    1060. HLA-DR allele frequencies in Mexican mestizos with au toimmune liver diseases including overlap syndromes. (PubMed id 19811438)1 Zepeda-Gomez S....Vargas-AlarcA^n G. (2009)
    1061. Genetic variation of promoter sequence modulates XBP1 expression and genetic risk for vitiligo. (PubMed id 19543371)1 Ren Y....Zhang X. (2009)
    1062. Gene-environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident RA. (PubMed id 19151010)1 Karlson E.W....Costenbader K.H. (2009)
    1063. The binding of antigenic peptides to HLA-DR is influe nced by interactions between pocket 6 and pocket 9. (PubMed id 19648278)1 James E.A....Kwok W.W. (2009)
    1064. Homozygosity of the polymorphism MICA5.1 identifies e xtreme risk of progression to overt adrenal insufficiency among 21-hydroxylase antibody-positive patients with type 1 diabetes. (PubMed id 19820007)1 Triolo T.M....Barker J.M. (2009)
    1065. Specific interaction between genotype, smoking and au toimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthrit is. (PubMed id 19898480)1 Mahdi H....Lundberg K. (2009)
    1066. Autoantibodies, polymorphisms in the serotonin pathwa y, and human leukocyte antigen class II alleles in chronic fatigue syndrome: ar e they associated with age at onset and specific symptoms? (PubMed id 19758204)1 Ortega-Hernandez O.D....Shoenfeld Y. (2009)
    1067. Phenotypic variance in childhood coeliac disease and the HLA-DQ/DR dose effect. (PubMed id 18932050)1 Vermeulen B.A....Mearin M.L. (2009)
    1068. HLA B27 as predisposition factor to suffer age relate d macular degeneration. (PubMed id 19728932)1 Villegas Becerril E....Gallardo Galera J.M. (2009)
    1069. Ethnic differences in immunogenetic features and photosensitivity of cutaneous lupus erythematosus. (PubMed id 18797890)1 Furukawa F. and Muto M. (2009)
    1070. High-resolution human leukocyte antigen (HLA) haploty pes and linkage disequilibrium of HLA-B and -C and HLA-DRB1 and -DQB1 alleles i n a Taiwanese population. (PubMed id 19480851)1 Yang K.L....Lin P.Y. (2009)
    1071. Polymorphisms of HLA genes in Western Javanese (Indonesia): close affinities to Southeast Asian populations. (PubMed id 19140832)1 Yuliwulandari R....Tokunaga K. (2009)
    1072. Immunogenetic Risks of Anti-Cyclical Citrullinated Peptide Antibodies in a North American Native Population with Rheumatoid Arthritis and Their First-degree Relatives. (PubMed id 19411392)1 El-Gabalawy H.S....Oen K. (2009)
    1073. Association of HLA-A, B, DRB1 alleles and haplotypes with HIV-1 infection in Chongqing, China. (PubMed id 20003377)1 Huang X....Xiong H. (2009)
    1074. The tag SNP for HLA-DRB11501, rs3135388, is significantly associated with multiple sclerosis susceptibility: Cost-effective high-throughput detection by real-time PCR. (PubMed id 19433080)1 ZivkoviA8 M....AlavantiA8 D. (2009)
    1075. Meta-analysis of genome scans and replication identif y CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. (PubMed id 19525953)1 De Jager P.L.... J.R. (2009)
    1076. HLA allele and haplotype frequencies in the Albanian population and their relationship with the other European populations. (PubMed id 19703234)1 Sulcebe G....Kardhashi V. (2009)
    1077. Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis. (PubMed id 19333951)1 van der Woude D....de Vries R.R. (2009)
    1078. Association of cytotoxic T lymphocyte antigen-4 gene polymorphisms and HLA class II alleles with the development of type 1 diabetes in Korean children and adolescents. (PubMed id 19949652)1 Jung M.H....Lee B.C. (2009)
    1079. HLA-DRB1 and multiple sclerosis in Argentina. (PubMed id 19364369)1 Patrucco L....Cristiano E. (2009)
    1080. Effect of the human leukocyte antigen HLA-DRB1 and an ti-cyclic citrullinated peptide on the outcome of rheumatoid arthritis patients . (PubMed id 19738989)1 Farouk H.M....Zarouk W.A. (2009)
    1081. HLA class II polymorphism in patients with type 1 dia betes mellitus from a Brazilian racially admixtured population. (PubMed id 20073143)1 Alves C....Carvalho G.C. (2009)
    1082. Common polygenic variation contributes to risk of sch izophrenia and bipolar disorder. (PubMed id 19571811)1 (2009)
    1083. HLA polymorphism in six Malay subethnic groups in Malaysia. (PubMed id 19364514)1 Edinur H.A....Norazmi M.N. (2009)
    1084. Influence of nitric oxide synthase gene polymorphisms on the risk of cardiovascular events in rheumatoid arthritis. (PubMed id 19327239)1 Gonzalez-Gay M.A....Martin J. (2009)
    1085. The common Scandinavian human leucocyte antigen ancestral haplotype 62.1 as prognostic factor in patients with advanced malignant melanoma. (PubMed id 19214504)1 Helgadottir H....Masucci G.V. (2009)
    1086. Protective role of the HLA-A*02 allele in Portuguese patients with multiple sclerosis. (PubMed id 19482867)1 Silva A.M....Martins B. (2009)
    1087. Identification of HLA-A*02-B*46 haplotype allele variant in Guangdong Han populations on the basis of PCR-SBT. (PubMed id 19348686)1 Xiong F....Huang F. (2009)
    1088. T cell responses to steroid cytochrome P450 21-hydrox ylase in patients with autoimmune primary adrenal insufficiency. (PubMed id 19890026)1 Bratland E....Husebye E.S. (2009)
    1089. The role of polymorphic protein tyrosine phosphatase non-receptor type 22 in leprosy. (PubMed id 19516267)1 Rani R....Kar H.K. (2009)
    1090. HLA genes in Uros from Titikaka Lake, Peru: origin an d relationship with other Amerindians and worldwide populations. (PubMed id 19490211)1 Arnaiz-Villena A....Moscoso J. (2009)
    1091. HLA antigens and nontuberculous mycobacterial lung disease in korean patients. (PubMed id 19219503)1 Um S.W....Koh W.J. (2009)
    1092. Association of HLA alleles with hepatitis C infection in Maharashtra, western India. (PubMed id 20090103)1 Tripathy A.S....Arankalle V.A. (2009)
    1093. Positive association of DRB1 04 and DRB1 15 alleles w ith Fya immunization in a Southern European population. (PubMed id 19702653)1 Picard C....Chiaroni J. (2009)
    1094. Sporadic inclusion body myositis: HLA-DRB1 allele int eractions influence disease risk and clinical phenotype. (PubMed id 19720533)1 Mastaglia F.L....Christiansen F.T. (2009)
    1095. Genome Wide Association Study of Determinants of Anti-cyclic Citrullinated Peptide Antibody Titer in Adults with Rheumatoid Arthritis. (PubMed id 19287509)1 Cui J....Karlson E. (2009)
    1096. Is neuromyelitis optica associated with human leukocyte antigen? (PubMed id 19299434)1 ZAcphir H....de Seze J. (2009)
    1097. Anti-'Mi(a)' immunization is associated with HLA-DRB1*0901. (PubMed id 19243543)1 Chu C.C....Lin M. (2009)
    1098. Identification of MICA as a Susceptibility Gene for Pulmonary Mycobacterium avium Complex Infection. (PubMed id 19405864)1 Shojima J....Inoko H. (2009)
    1099. The frequency of HLA class I and II alleles in Pakist ani patients with aplastic anemia. (PubMed id 19860590)1 Rehman S....Mehmood T. (2009)
    1100. TNF-alpha polymorphisms in primary biliary cirrhosis: a northern and southern Italian experience. (PubMed id 19758199)1 Niro G.A....Invernizzi P. (2009)
    1101. TRAF1/C5 polymorphism is not associated with pemphigus. (PubMed id 19416238)1 Mejri K....Makni S. (2009)
    1102. HLA-DRB1*1501 and spinal cord magnetic resonance imag ing lesions in multiple sclerosis. (PubMed id 20008659)1 Sombekke M.H....Polman C.H. (2009)
    1103. A diabetes-specific HLA-DR restricted pro-inflammatory T cell response to wheat polypeptides in tissue transglutaminase antibody negative patients with type 1 diabetes. (PubMed id 19401421)1 Mojibian M....Scott F.W. (2009)
    1104. [Correlation between HLA-DRB1*0901 and 1501, HLA-DQB1 *0301 and 0602 alleles and esophageal squamous cell carcinoma of Kazakh in Xinj iang, China.] (PubMed id 20193456)1 Chen Y.Z....Li F. (2009)
    1105. Synergistic effect of HLA class II loci and cytokine gene polymorphisms on the risk of gastric cancer in Japanese patients with Heli cobacter pylori infection. (PubMed id 19544559)1 Ando T....Yoshikawa T. (2009)
    1106. 3-Layer-based analysis of peptide-MHC interaction: in silico prediction, peptide binding affinity and T cell activation in a relevan t allergen-specific model. (PubMed id 19232439)1 Knapp B....Jahn-Schmid B. (2009)
    1107. Association of HY-restricting HLA class II alleles with pregnancy outcome in patients with recurrent miscarriage subsequent to a firstborn boy. (PubMed id 19223392)1 Nielsen H.S....Christiansen O.B. (2009)
    1108. HLA-B is the best candidate of susceptibility genes i n HLA for Japanese ulcerative colitis. (PubMed id 19493234)1 Aizawa H....Shimosegawa T. (2009)
    1109. Genomewide association study of leprosy. (PubMed id 20018961)1 Zhang F.R....Liu J.J. (2009)
    1110. Integration of genetic risk factors into a clinical a lgorithm for multiple sclerosis susceptibility: a weighted genetic risk score. (PubMed id 19879194)1 De Jager P.L.... E.W. (2009)
    1111. HLA-DRB1 among patients with Vogt-Koyanagi-Harada dis ease in Saudi Arabia. (PubMed id 19756183)1 Iqniebi A....Tabbara K.F. (2009)
    1112. HLA DRB1*130101-DQB1*060101 haplotype is associated with acute chest syndrome in sickle cell anemia patients. (PubMed id 19254255)1 Mahdi N....Almawi W.Y. (2009)
    1113. MHC Class II alleles in ulcerative colitis-associated colorectal cancer. (PubMed id 19251712)1 Garrity-Park M.M....Smyrk T.C. (2009)
    1114. Molecular study of receptor for advanced glycation en dproduct gene promoter and identification of specific HLA haplotypes possibly i nvolved in chronic fatigue syndrome. (PubMed id 19822091)1 Carlo-Stella N....Cuccia M. (2009)
    1115. Tunisian endemic pemphigus foliaceus is associated wi th the HLA-DR3 gene: anti-desmoglein 1 antibody-positive healthy subjects bear protective alleles. (PubMed id 19486004)1 Abida O....Masmoudi H. (2009)
    1116. Association of the human leukocyte antigen class II a lleles with chronic atrophic gastritis and gastric carcinoma in Koreans. (PubMed id 19906105)1 Lee H.W....Lee K.W. (2009)
    1117. Thirty-six novel HLA alleles: 7 HLA-A, 11 HLA-B, 15 HLA-C and 3 HLA- DRB1. (PubMed id 19744147)1 Anholts J.D.... Oudshoorn M. (2009)
    1118. Investigating the viability of genetic screening/test ing for RA susceptibility using combinations of five confirmed risk loci. (PubMed id 19741008)1 McClure A....Barton A. (2009)
    1119. Association of HLA-DR and -DQ Genes with Familial Moy amoya Disease in Koreans. (PubMed id 20062572)1 Hong S.H....Park M.H. (2009)
    1120. Acute disseminated encephalomyelitis: clinical featur es, HLA DRB1*1501, HLA DRB1*1503, HLA DQA1*0102, HLA DQB1*0602, and HLA DPA1*03 01 allelic association study. (PubMed id 19722042)1 Alves-Leon S.V....Quirico-Santos T. (2009)
    1121. HLA type and immune response to Borrelia burgdorferi outer surface protein a in people in whom arthritis developed after Lyme disease vaccination. (PubMed id 19333928)1 Ball R....Braun M.M. (2009)
    1122. Genetic factors in mother-to-child transmission of HC V infection. (PubMed id 19481774)1 Bevilacqua E....Amoroso A. (2009)
    1123. Molecular variation at the HLA-A, B, C, DRB1, DQA1, a nd DQB1 loci in full heritage American Indians in Arizona: private haplotypes a nd their evolution. (PubMed id 19845915)1 Williams R....Knowler W. (2009)
    1124. CD74 in antigen presentation, inflammation, and cancers of the gastrointestinal tract. (PubMed id 19533806)2 Beswick E.J. and Reyes V.E. (2009)
    1125. HLA-A disparities illustrate challenges for ranking t he impact of HLA mismatches on bone marrow transplant outcomes in the United St ates. (PubMed id 19589487)1 Baxter-Lowe L.A....Hurley C.K. (2009)
    1126. The frequent and conserved DR3-B8-A1 extended haplotype confers less diabetes risk than other DR3 haplotypes. (PubMed id 19143812)1 Baschal E.E....Eisenbarth G.S. (2009)
    1127. Human leukocyte antigens among primary biliary cirrhosis patients born in Mexico. (PubMed id 19221531)1 VA!zquez-Elizondo G....MAcndez-SA!nchez N. (2009)
    1128. Multiple sclerosis susceptibility alleles in African Americans. (PubMed id 19865102)1 Johnson B.A....Oksenberg J.R. (2009)
    1129. Clear and independent associations of several HLA-DRB 1 alleles with differential antibody responses to hepatitis B vaccination in yo uth. (PubMed id 19597844)1 Li Y....Tang J. (2009)
    1130. Full likelihood analysis of genetic risk with variabl e age at onset disease--combining population-based registry data and demographi c information. (PubMed id 19718441)1 PitkAoniemi J....Arjas E. (2009)
    1131. [Analysis on haplotypes of five HLA loci in southern Chinese Han population by sequence-based typing.] (PubMed id 19350523)1 Gao S....Deng Z. (2009)
    1132. HLA-association of serum levels of natural antibodies. (PubMed id 19167759)1 Pozsonyi E....FA1st G. (2009)
    1133. Replication of rubella vaccine population genetic stu dies: validation of HLA genotype and humoral response associations. (PubMed id 19761839)1 Ovsyannikova I.G....Poland G.A. (2009)
    1134. High-resolution HLA genotyping and severe cutaneous a dverse reactions in lamotrigine-treated patients. (PubMed id 19668019)1 Kazeem G.R....Foot E. (2009)
    1135. HLA haplotype A33-B58-Cw10 may modulate radiographic development of bamboo spine in Taiwanese patients with primary ankylosing spondylitis. (PubMed id 19407364)1 Lu M.C....Lai N.S. (2009)
    1136. IFIH1-GCA-KCNH7 locus is not associated with genetic susceptibility to multiple sclerosis in French patients. (PubMed id 19156166)1 Couturier N....Brassat D. (2009)
    1137. High resolution human leukocyte antigen (HLA) class I and class II allele typing in Mexican mestizo women with sporadic breast cancer: case-control study. (PubMed id 19196481)1 CantA_ de LeA^n D....Granados J. (2009)
    1138. Additional sequence analysis outside exon 2 clarifies DRB1*12 and DRB1*14 allelic frequencies in Koreans. (PubMed id 19286445)1 Lee K.W. and Jung Y.A. (2009)
    1139. Analysis of HLA class I and II alleles regarding to lymph node and distant metastasis in patients with non-small cell lung cancer. (PubMed id 19246116)1 Bulut I....Gorguner M. (2009)
    1140. Parent-of-origin of HLA-DRB1*1501 and age of onset of multiple sclerosis. (PubMed id 19629136)1 Ramagopalan S.V....Sadovnick A.D. (2009)
    1141. [Relation of HLA-DRB1*15 with pathogenesis in 162 chi ldhood cases of acute lymphoblastic leukemia] (PubMed id 20030936)1 Wang X.J....Zhu X.F. (2009)
    1142. Association of HLA class II genes with systemic scler osis in Spanish patients. (PubMed id 19884273)1 SimeA^n C.P....Vilardell M. (2009)
    1143. HLA-DR and HLA-DQ alleles in patients from the south of Brazil: markers for leprosy susceptibility and resistance. (PubMed id 19698125)1 da Silva S.A....Visentainer J.E. (2009)
    1144. Modification of Multiple Sclerosis Phenotypes by African Ancestry at HLA. (PubMed id 19204159)1 Cree B.A....Oksenberg J.R. (2009)
    1145. Variation in the ATP-binding cassette transporter 2 gene is a separate risk factor for systemic lupus erythematosus within the MHC. (PubMed id 19387463)1 Ramos P.S....Moser K.L. (2009)
    1146. [Association of hemorrhagic fever with renal syndrome and HLA-DRB allele polymorphisms in Han nationality, Hubei province.] (PubMed id 20193583)1 Wei B....Tang X.Y. (2009)
    1147. The HLA DRB1*1501-DQB1*0602-DPB1*0501 haplotype is a risk factor for toluene diisocyanate-induced occupational asthma. (PubMed id 19439981)1 Choi J.H....Park H.S. (2009)
    1148. Long-range linkage on chromosome 6p of VEGF, FKBP5, HLA and TNF alleles associated with transplant rejection. (PubMed id 19233472)1 Chen Y....Hutchinson I.V. (2009)
    1149. Association between protective and deleterious HLA al leles with multiple sclerosis in Central East Sardinia. (PubMed id 19654877)1 Pastorino R....Bernardinelli L. (2009)
    1150. The effect of the MHC locus on autoantibodies in type 1 diabetes. (PubMed id 19429597)1 Qu H.Q. and Polychronakos C. (2009)
    1151. HLA class I and class II polymorphisms in Saudi patie nts with myasthenia gravis. (PubMed id 19490212)1 Hajeer A.H....Al Jumah M. (2009)
    1152. HLA-DQ, DR allele polymorphism of type 1 diabetes in the Chinese population: a meta-analysis. (PubMed id 19493426)1 Zhang X.M....Ji L.N. (2009)
    1153. Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1. (PubMed id 19143814)1 Valdes A.M. and Thomson G. (2009)
    1154. Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. (PubMed id 19525955)1 (2009)
    1155. HLA-B62 and HLA-DQ8 are associated with Complex Regio nal Pain Syndrome with fixed dystonia. (PubMed id 19523767)1 de Rooij A.M....van Hilten J.J. (2009)
    1156. Effects of infectious mononucleosis and HLA-DRB1*15 i n multiple sclerosis. (PubMed id 19153174)1 Nielsen T.R....Hjalgrim H. (2009)
    1157. HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients. (PubMed id 19104471)1 Chantarangsu S....Nakamura Y. (2009)
    1158. HLA in Portuguese systemic lupus erythematosus patien ts and their relation to clinical features. (PubMed id 19758202)1 Vasconcelos C....Martins B. (2009)
    1159. Donor-recipient mismatches in MHC class I chain-relat ed gene A in unrelated donor transplantation lead to increased incidence of acu te graft-versus-host disease. (PubMed id 19654407)1 Parmar S....Fernandez-Vina M. (2009)
    1160. Do non-HLA genes influence development of persistent islet autoimmunity and type 1 diabetes in children with high-risk HLA-DR,DQ genotypes? (PubMed id 19188433)1 Steck A.K....Rewers M.J. (2009)
    1161. Epistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibility. (PubMed id 19380721)1 Lincoln M.R....Ebers G.C. (2009)
    1162. Polymorphism located between CPT1B and CHKB, and HLA- DRB1*1501-DQB1*0602 haplotype confer susceptibility to CNS hypersomnias (essent ial hypersomnia). (PubMed id 19404393)1 Miyagawa T....Tokunaga K. (2009)
    1163. A systematic meta-analysis of genetic association stu dies for diabetic retinopathy. (PubMed id 19587357)1 Abhary S....Craig J.E. (2009)
    1164. [Genetic predisposition to multiple sclerosis as a po lygenic autoimmune disease] (PubMed id 19894308)1 Favorova O.O....Ochs M.F. (2009)
    1165. The major histocompatibility complex conserved extend ed haplotype 8.1 in AIDS-related non-Hodgkin lymphoma. (PubMed id 19654554)1 Aissani B....Kaslow R.A. (2009)
    1166. Role of human leukocyte antigen, killer-cell immunogl obulin-like receptors, and cytokine gene polymorphisms in leptospirosis. (PubMed id 19683555)1 Fialho R.N....Bruges-Armas J. (2009)
    1167. [Study on the association between chronic hepatitis B cirrhosis and HLA-DRB1 * 1301,1302 allele] (PubMed id 20108780)1 Liang H.X....Jiang H.Q. (2009)
    1168. HIV-1 Nef promotes endocytosis of cell surface MHC cla ss II molecules via a constitutive pathway. (PubMed id 19620308)1 Chaudhry A....Rath S. (2009)
    1169. The non-inherited maternal HLA haplotype affects the risk for type 1 diabetes. (PubMed id 19055605)1 Akesson K....Kockum I. (2009)
    1170. HLA-DPB1 associations differ between DRB1*03 positive anti-Jo-1 and anti-PM-Scl antibody positive idiopathic inflammatory myopathy. (PubMed id 19690132)1 Chinoy H....Cooper R.G. (2009)
    1171. [DRB1 * 1454: the common allele of human leukocyte an tigen-DRB1 * 14 in Chinese Han populations] (PubMed id 20017299)1 Cheng L.H....Wang D.M. (2009)
    1172. Three microsatellites from the T1DGC MHC data set show highly significant association with type 1 diabetes, independent of the HLA-DRB1, -DQA1 and -DQB1 genes. (PubMed id 19143811)1 Eike M.C....Lie B.A. (2009)
    1173. HLA-DRB1 Alleles are Associated with the Clinical Cou rse of Disease and Steroid Dependence in Mexican Patients with Ulcerative Colit is. (PubMed id 19674023)1 Yamamoto-Furusho J.K....Granados J. (2009)
    1174. HLA-A *3303* and *3301 predispose patients to persist ent hepatitis B infection. (PubMed id 19337647)1 Ramezani A....Velayati A.A. (2009)
    1175. Influence of HLA-DRB1 Alleles on Antibody Responses to PfCP-2.9-Immunized and Naturally Infected Individuals. (PubMed id 19247821)1 Zhang Q....Pan W. (2009)
    1176. Primary autoimmune neutropenia in children in Taiwan. (PubMed id 19210322)1 Wang L.Y....Lin M. (2009)
    1177. Killer immunoglobulin-like receptor ligand HLA-Bw4 pr otects against multiple sclerosis. (PubMed id 19630074)1 Lorentzen A.R....Harbo H.F. (2009)
    1178. Gene-environment interaction between the DRB1 shared epitope and smoking in the risk of anti-citrullinated protein antibody-positive rheumatoid arthritis: all alleles are important. (PubMed id 19479873)1 LundstrAPm E....Padyukov L. (2009)
    1179. Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study. (PubMed id 19122664)1 Silverberg M.S....Duerr R.H. (2009)
    1180. HLA-DRB115 and cerebrospinal-fluid-specific oligoclon al immunoglobulin G bands lower age at attainment of important disease mileston es in multiple sclerosis. (PubMed id 19327846)1 Imrell K....Masterman T. (2009)
    1181. Association of MHC SNP genotype with susceptibility to type 1 diabetes: a modified survival approach. (PubMed id 19143821)1 McKinnon E....James I. (2009)
    1182. Autoimmune type 1 diabetes genetic susceptibility enc oded by human leukocyte antigen DRB1 and DQB1 genes in Tunisia. (PubMed id 19553558)1 Stayoussef M....Almawi W.Y. (2009)
    1183. Haplotype-based search for SNPs associated with differential type 1 diabetes risk among chromosomes carrying a specific HLA DRB1-DQA1-DQB1 haplotype. (PubMed id 19143810)1 McGinnis R....Deloukas P. (2009)
    1184. The Value of HLA-DRB1 Shared Epitope, -308 Tumor Necrosis Factor-{alpha} Gene Promoter Polymorphism, Rheumatoid Factor, Anti-Citrullinated Peptide Antibodies, and Early Erosions for Predicting Radiological Outcome in Recent-Onset Rheumatoid Arthritis. (PubMed id 19411391)1 Reneses S....GarcA-a A. (2009)
    1185. HLA-DRB1 associations with disease susceptibility and clinical course in Australians with multiple sclerosis. (PubMed id 19392788)1 Stankovich J....Rubio J.P. (2009)
    1186. Clinical, immunological, and genetic features of auto immune primary adrenal insufficiency: observations from a Norwegian registry. (PubMed id 19858318)1 Erichsen M.M....Husebye E.S. (2009)
    1187. Association of the HLA-DPB1*0501 allele with anti-aquaporin-4 antibody positivity in Japanese patients with idiopathic central nervous system demyelinating disorders. (PubMed id 19140826)1 Matsushita T....Kira J. (2009)
    1188. Experimental and clinical characteristics in myelodys plastic syndrome patients with or without HLA-DR15 allele. (PubMed id 19593744)