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Aliases for HLA-DPB2 Gene

Aliases for HLA-DPB2 Gene

  • Major Histocompatibility Complex, Class II, DP Beta 2 (Pseudogene) 2 3
  • HLA-DP2B 3
  • DPbeta2 3
  • COL11A2 6
  • DFNA13 6
  • DFNB53 6
  • FBCG2 6
  • STL3 6
  • DP2B 3
  • DPB2 3

External Ids for HLA-DPB2 Gene

Previous Symbols for HLA-DPB2 Gene

  • HLA-DP2B

Summaries for HLA-DPB2 Gene

GeneCards Summary for HLA-DPB2 Gene

HLA-DPB2 (Major Histocompatibility Complex, Class II, DP Beta 2 (Pseudogene)) is a Pseudogene. Diseases associated with HLA-DPB2 include otospondylomegaepiphyseal dysplasia and fibrochondrogenesis. Among its related pathways are PI3K-Akt signaling pathway and ERK Signaling.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HLA-DPB2 Gene

Genomics for HLA-DPB2 Gene

Genomic Location for HLA-DPB2 Gene

Start:
33,112,451 bp from pter
End:
33,129,113 bp from pter
Size:
16,663 bases
Orientation:
Plus strand

Genomic View for HLA-DPB2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for HLA-DPB2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Regulatory Elements for HLA-DPB2 Gene

Proteins for HLA-DPB2 Gene

Post-translational modifications for HLA-DPB2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HLA-DPB2 Gene

Domains for HLA-DPB2 Gene

Gene Families for HLA-DPB2 Gene

HGNC:
  • HLA :Histocompatibility complex
genes like me logo Genes that share domains with HLA-DPB2: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for HLA-DPB2 Gene

Function for HLA-DPB2 Gene

Molecular function for HLA-DPB2 Gene

GENATLAS Biochemistry: HLA-DP,beta chain-related pseudogene

Phenotypes for HLA-DPB2 Gene

GenomeRNAi human phenotypes for HLA-DPB2:
genes like me logo Genes that share phenotypes with HLA-DPB2: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for HLA-DPB2 Gene

Localization for HLA-DPB2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for HLA-DPB2 Gene COMPARTMENTS Subcellular localization image for HLA-DPB2 gene
Compartment Confidence
lysosome 2

No data available for Gene Ontology (GO) - Cellular Components for HLA-DPB2 Gene

Pathways for HLA-DPB2 Gene

genes like me logo Genes that share pathways with HLA-DPB2: view

Interacting Proteins for HLA-DPB2 Gene

Gene Ontology (GO) - Biological Process for HLA-DPB2 Gene

None

Transcripts for HLA-DPB2 Gene

mRNA/cDNA for HLA-DPB2 Gene

Unigene Clusters for HLA-DPB2 Gene

Major histocompatibility complex, class II, DP beta 2 (pseudogene):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HLA-DPB2 Gene

No ASD Table

Relevant External Links for HLA-DPB2 Gene

GeneLoc Exon Structure for
HLA-DPB2
ECgene alternative splicing isoforms for
HLA-DPB2

Expression for HLA-DPB2 Gene

mRNA expression in normal human tissues for HLA-DPB2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for HLA-DPB2 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (5.0) and Brain - Cerebellum (4.6).

SOURCE GeneReport for Unigene cluster for HLA-DPB2 Gene Hs.665450

genes like me logo Genes that share expressions with HLA-DPB2: view

Orthologs for HLA-DPB2 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for HLA-DPB2 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia H2-Pb 16
Species with no ortholog for HLA-DPB2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for HLA-DPB2 Gene

ENSEMBL:
Gene Tree for HLA-DPB2 (if available)
TreeFam:
Gene Tree for HLA-DPB2 (if available)

Paralogs for HLA-DPB2 Gene

No data available for Paralogs for HLA-DPB2 Gene

Variants for HLA-DPB2 Gene

Structural Variations from Database of Genomic Variants (DGV) for HLA-DPB2 Gene

Variant ID Type Subtype PubMed ID
dgv1047e201 CNV Deletion 23290073
nsv516221 CNV Loss 19592680
esv33191 CNV Gain 17666407
esv32606 CNV Gain 17666407
esv2650098 CNV Deletion 19546169
esv2199795 CNV Deletion 18987734
esv3157 CNV Deletion 18987735
esv2731885 CNV Deletion 23290073
esv2676552 CNV Deletion 23128226
esv7387 CNV Loss 19470904
nsv885767 CNV Loss 21882294

Relevant External Links for HLA-DPB2 Gene

HapMap Linkage Disequilibrium report
HLA-DPB2
Human Gene Mutation Database (HGMD)
HLA-DPB2
Locus Specific Mutation Databases (LSDB)
HLA-DPB2

No data available for Sequence variations from dbSNP and Humsavar for HLA-DPB2 Gene

Disorders for HLA-DPB2 Gene

(6) OMIM Diseases for HLA-DPB2 Gene (120290)

(1) University of Copenhagen DISEASES for HLA-DPB2 Gene

Relevant External Links for HLA-DPB2

Genetic Association Database (GAD)
HLA-DPB2
Human Genome Epidemiology (HuGE) Navigator
HLA-DPB2
genes like me logo Genes that share disorders with HLA-DPB2: view

No data available for UniProtKB/Swiss-Prot for HLA-DPB2 Gene

Publications for HLA-DPB2 Gene

  1. Analysis of 17,576 potentially functional SNPs in three case-control studies of myocardial infarction. (PMID: 18682748) Shiffman D. … Devlin J.J. (PLoS ONE 2008) 3 49
  2. HLA-DPB1 and DPB2 are genetic loci for systemic sclerosis: a genome-wide association study in Koreans with replication in North Americans. (PMID: 19950302) Zhou X. … Lee E.B. (Arthritis Rheum. 2009) 3 49
  3. A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project. (PMID: 20031603) Marroni F. … Pramstaller P.P. (Circ Cardiovasc Genet 2009) 3 49
  4. Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. (PMID: 20587610) Ucisik-Akkaya E. … Dorak M.T. (Mol. Hum. Reprod. 2010) 3 49
  5. Genome-wide association study identifies susceptibility loci for IgA nephropathy. (PMID: 21399633) Gharavi A.G. … Lifton R.P. (Nat. Genet. 2011) 3 49

Products for HLA-DPB2 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate HLA-DPB2
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for HLA-DPB2
    • Block miRNA regulation of HLA-DPB2 using miScript Target Protectors

    Sources for HLA-DPB2 Gene

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