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Aliases for HLA-DPB2 Gene

Aliases for HLA-DPB2 Gene

  • Major Histocompatibility Complex, Class II, DP Beta 2 (Pseudogene) 2 3 5
  • HLA-DP2B 3
  • DPbeta2 3
  • DP2B 3
  • DPB2 3

External Ids for HLA-DPB2 Gene

Previous HGNC Symbols for HLA-DPB2 Gene

  • HLA-DP2B

Previous GeneCards Identifiers for HLA-DPB2 Gene

  • GC06U990045
  • GC06P033127
  • GC06P033188
  • GC06P032822

Summaries for HLA-DPB2 Gene

GeneCards Summary for HLA-DPB2 Gene

HLA-DPB2 (Major Histocompatibility Complex, Class II, DP Beta 2 (Pseudogene)) is a Pseudogene. Among its related pathways are G-protein signaling N-RAS regulation pathway and Immune response NFAT in immune response.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HLA-DPB2 Gene

Genomics for HLA-DPB2 Gene

Regulatory Elements for HLA-DPB2 Gene

Enhancers for HLA-DPB2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F033079 0.2 ENCODE 47.1 -31.7 -31709 2.0 PKNOX1 KLF17 GLI4 ZNF2 ZNF121 GLIS2 ZNF366 ZNF391 EGR2 ZNF263 HLA-DPB1 HLA-DPB2 HLA-DPA1 RPL32P1 HLA-DMA HLA-DPA3 RPS18 GC06P033079
GH06F033142 0.5 Ensembl 17.7 +30.9 30850 1.0 CTCF RAD51 USF1 SPI1 HLA-DPA1 HLA-DPB1 HLA-DPB2 HSD17B8 COL11A2 RPL32P1 HLA-DPA3 PIR47274
GH06F033116 0.8 Ensembl ENCODE 15.1 +5.1 5110 2.5 HDGF BCOR ELF3 CTCF PKNOX1 TEAD4 MAX ZMYM3 EBF1 ZNF2 HLA-DPB1 HLA-DPA1 HLA-DPB2 HCG24 RPL32P1 COL11A2 HSD17B8 PIR46525 PIR47274
GH06F033145 0.7 Ensembl ENCODE 12.5 +32.2 32150 0.4 CTCF PKNOX1 ATF1 YY2 CEBPB MAX JUND RFXANK PBX2 NFYB HLA-DPB2 COL11A2 HLA-DPA1 RPL32P1 HLA-DPB1 HSD17B8 HCG24
GH06F033144 0.2 Ensembl 10 +31.7 31650 0.2 HLA-DPB1 COL11A2 RPL32P1 HLA-DPA1 HLA-DPB2 HCG24
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around HLA-DPB2 on UCSC Golden Path with GeneCards custom track

Genomic Location for HLA-DPB2 Gene

Chromosome:
6
Start:
33,112,451 bp from pter
End:
33,129,113 bp from pter
Size:
16,663 bases
Orientation:
Plus strand

Genomic View for HLA-DPB2 Gene

Genes around HLA-DPB2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HLA-DPB2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HLA-DPB2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for HLA-DPB2 Gene

Post-translational modifications for HLA-DPB2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HLA-DPB2 Gene

Domains & Families for HLA-DPB2 Gene

Gene Families for HLA-DPB2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HLA-DPB2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HLA-DPB2 Gene

Function for HLA-DPB2 Gene

Molecular function for HLA-DPB2 Gene

GENATLAS Biochemistry:
HLA-DP,beta chain-related pseudogene

Phenotypes for HLA-DPB2 Gene

GenomeRNAi human phenotypes for HLA-DPB2:
genes like me logo Genes that share phenotypes with HLA-DPB2: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HLA-DPB2 Gene

Localization for HLA-DPB2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HLA-DPB2 Gene

Pathways & Interactions for HLA-DPB2 Gene

genes like me logo Genes that share pathways with HLA-DPB2: view

Interacting Proteins for HLA-DPB2 Gene

Gene Ontology (GO) - Biological Process for HLA-DPB2 Gene

None

No data available for SIGNOR curated interactions for HLA-DPB2 Gene

Drugs & Compounds for HLA-DPB2 Gene

(1) Drugs for HLA-DPB2 Gene - From: PharmGKB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Aspirin Approved, Vet_approved Pharma Channel blocker 1112
genes like me logo Genes that share compounds with HLA-DPB2: view

Transcripts for HLA-DPB2 Gene

mRNA/cDNA for HLA-DPB2 Gene

Unigene Clusters for HLA-DPB2 Gene

Major histocompatibility complex, class II, DP beta 2 (pseudogene):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HLA-DPB2 Gene

No ASD Table

Relevant External Links for HLA-DPB2 Gene

GeneLoc Exon Structure for
HLA-DPB2
ECgene alternative splicing isoforms for
HLA-DPB2

Expression for HLA-DPB2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for HLA-DPB2 Gene

mRNA differential expression in normal tissues according to GTEx for HLA-DPB2 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x5.0) and Brain - Cerebellum (x4.6).

SOURCE GeneReport for Unigene cluster for HLA-DPB2 Gene:

Hs.665450
genes like me logo Genes that share expression patterns with HLA-DPB2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for HLA-DPB2 Gene

Orthologs for HLA-DPB2 Gene

Evolution for HLA-DPB2 Gene

ENSEMBL:
Gene Tree for HLA-DPB2 (if available)
TreeFam:
Gene Tree for HLA-DPB2 (if available)

No data available for Orthologs for HLA-DPB2 Gene

Paralogs for HLA-DPB2 Gene

No data available for Paralogs for HLA-DPB2 Gene

Variants for HLA-DPB2 Gene

Structural Variations from Database of Genomic Variants (DGV) for HLA-DPB2 Gene

Variant ID Type Subtype PubMed ID
dgv1000e201 CNV deletion 23290073
dgv1760e212 CNV loss 25503493
esv2199795 CNV deletion 18987734
esv2650098 CNV deletion 19546169
esv2676552 CNV deletion 23128226
esv2731885 CNV deletion 23290073
esv3157 CNV loss 18987735
esv32606 CNV gain 17666407
esv33191 CNV gain 17666407
esv3567589 CNV deletion 23714750
esv7387 CNV loss 19470904
nsv1024429 CNV loss 25217958
nsv1073969 CNV deletion 25765185
nsv1112900 CNV deletion 24896259
nsv1119076 CNV deletion 24896259
nsv516221 CNV loss 19592680
nsv602818 CNV loss 21841781

Relevant External Links for HLA-DPB2 Gene

Human Gene Mutation Database (HGMD)
HLA-DPB2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
HLA-DPB2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for HLA-DPB2 Gene

Disorders for HLA-DPB2 Gene

Relevant External Links for HLA-DPB2

Genetic Association Database (GAD)
HLA-DPB2
Human Genome Epidemiology (HuGE) Navigator
HLA-DPB2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HLA-DPB2

No disorders were found for HLA-DPB2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HLA-DPB2 Gene

Publications for HLA-DPB2 Gene

  1. Genome-wide association study identifies susceptibility loci for IgA nephropathy. (PMID: 21399633) Gharavi A.G. … Lifton R.P. (Nat. Genet. 2011) 3 46 64
  2. Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. (PMID: 20587610) Ucisik-Akkaya E. … Dorak M.T. (Mol. Hum. Reprod. 2010) 3 46 64
  3. A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project. (PMID: 20031603) Marroni F. … Pramstaller P.P. (Circ Cardiovasc Genet 2009) 3 46 64
  4. HLA-DPB1 and DPB2 are genetic loci for systemic sclerosis: a genome-wide association study in Koreans with replication in North Americans. (PMID: 19950302) Zhou X. … Lee E.B. (Arthritis Rheum. 2009) 3 46 64
  5. Analysis of 17,576 potentially functional SNPs in three case-control studies of myocardial infarction. (PMID: 18682748) Shiffman D. … Devlin J.J. (PLoS ONE 2008) 3 46 64

Products for HLA-DPB2 Gene

Sources for HLA-DPB2 Gene

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