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Aliases for HLA-DPB2 Gene

Aliases for HLA-DPB2 Gene

  • Major Histocompatibility Complex, Class II, DP Beta 2 (Pseudogene) 2 3 5
  • HLA-DP2B 3
  • DPbeta2 3
  • DP2B 3
  • DPB2 3

External Ids for HLA-DPB2 Gene

Previous HGNC Symbols for HLA-DPB2 Gene

  • HLA-DP2B

Previous GeneCards Identifiers for HLA-DPB2 Gene

  • GC06U990045
  • GC06P033127
  • GC06P033188
  • GC06P032822

Summaries for HLA-DPB2 Gene

GeneCards Summary for HLA-DPB2 Gene

HLA-DPB2 (Major Histocompatibility Complex, Class II, DP Beta 2 (Pseudogene)) is a Pseudogene. Among its related pathways are Immune response NFAT in immune response and Immune response Antigen presentation by MHC class II.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HLA-DPB2 Gene

Genomics for HLA-DPB2 Gene

Regulatory Elements for HLA-DPB2 Gene

Genomic Location for HLA-DPB2 Gene

Chromosome:
6
Start:
33,112,451 bp from pter
End:
33,129,113 bp from pter
Size:
16,663 bases
Orientation:
Plus strand

Genomic View for HLA-DPB2 Gene

Genes around HLA-DPB2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HLA-DPB2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HLA-DPB2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for HLA-DPB2 Gene

Post-translational modifications for HLA-DPB2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HLA-DPB2 Gene

Domains & Families for HLA-DPB2 Gene

Gene Families for HLA-DPB2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HLA-DPB2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HLA-DPB2 Gene

Function for HLA-DPB2 Gene

Molecular function for HLA-DPB2 Gene

GENATLAS Biochemistry:
HLA-DP,beta chain-related pseudogene

Phenotypes for HLA-DPB2 Gene

GenomeRNAi human phenotypes for HLA-DPB2:
genes like me logo Genes that share phenotypes with HLA-DPB2: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HLA-DPB2 Gene

Localization for HLA-DPB2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HLA-DPB2 Gene

Pathways & Interactions for HLA-DPB2 Gene

genes like me logo Genes that share pathways with HLA-DPB2: view

Interacting Proteins for HLA-DPB2 Gene

Gene Ontology (GO) - Biological Process for HLA-DPB2 Gene

None

No data available for SIGNOR curated interactions for HLA-DPB2 Gene

Drugs & Compounds for HLA-DPB2 Gene

(1) Drugs for HLA-DPB2 Gene - From: PharmGKB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Aspirin Approved Pharma Channel blocker 1029
genes like me logo Genes that share compounds with HLA-DPB2: view

Transcripts for HLA-DPB2 Gene

mRNA/cDNA for HLA-DPB2 Gene

(3) Additional mRNA sequences :
(599) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HLA-DPB2 Gene

Major histocompatibility complex, class II, DP beta 2 (pseudogene):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HLA-DPB2 Gene

No ASD Table

Relevant External Links for HLA-DPB2 Gene

GeneLoc Exon Structure for
HLA-DPB2
ECgene alternative splicing isoforms for
HLA-DPB2

Expression for HLA-DPB2 Gene

mRNA expression in normal human tissues for HLA-DPB2 Gene

mRNA differential expression in normal tissues according to GTEx for HLA-DPB2 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x5.0) and Brain - Cerebellum (x4.6).

SOURCE GeneReport for Unigene cluster for HLA-DPB2 Gene Hs.665450

genes like me logo Genes that share expression patterns with HLA-DPB2: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for HLA-DPB2 Gene

Orthologs for HLA-DPB2 Gene

Evolution for HLA-DPB2 Gene

ENSEMBL:
Gene Tree for HLA-DPB2 (if available)
TreeFam:
Gene Tree for HLA-DPB2 (if available)

No data available for Orthologs for HLA-DPB2 Gene

Paralogs for HLA-DPB2 Gene

No data available for Paralogs for HLA-DPB2 Gene

Variants for HLA-DPB2 Gene

Structural Variations from Database of Genomic Variants (DGV) for HLA-DPB2 Gene

Variant ID Type Subtype PubMed ID
dgv1047e201 CNV Deletion 23290073
nsv516221 CNV Loss 19592680
esv33191 CNV Gain 17666407
esv32606 CNV Gain 17666407
esv2650098 CNV Deletion 19546169
esv2199795 CNV Deletion 18987734
esv3157 CNV Deletion 18987735
esv2731885 CNV Deletion 23290073
esv2676552 CNV Deletion 23128226
esv7387 CNV Loss 19470904
nsv885767 CNV Loss 21882294

Relevant External Links for HLA-DPB2 Gene

HapMap Linkage Disequilibrium report
HLA-DPB2
Human Gene Mutation Database (HGMD)
HLA-DPB2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for HLA-DPB2 Gene

Disorders for HLA-DPB2 Gene

Relevant External Links for HLA-DPB2

Genetic Association Database (GAD)
HLA-DPB2
Human Genome Epidemiology (HuGE) Navigator
HLA-DPB2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HLA-DPB2

No disorders were found for HLA-DPB2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HLA-DPB2 Gene

Publications for HLA-DPB2 Gene

  1. Genome-wide association study identifies susceptibility loci for IgA nephropathy. (PMID: 21399633) Gharavi A.G. … Lifton R.P. (Nat. Genet. 2011) 3 48 67
  2. Class II genes of the human major histocompatibility complex. Evolution of the DP region as deduced from nucleotide sequences of the four genes. (PMID: 3036829) Gustafsson K. … Peterson P.A. (J. Biol. Chem. 1987) 2 3
  3. A genome-wide association study on thyroid function and anti-thyroid peroxidase antibodies in Koreans. (PMID: 24722205) Kwak S.H. … Cho N.H. (Hum. Mol. Genet. 2014) 3
  4. Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis. (PMID: 23740775) Xie G. … Siminovitch K.A. (Arthritis Rheum. 2013) 3
  5. A genome-wide association study identifies two new cervical cancer susceptibility loci at 4q12 and 17q12. (PMID: 23817570) Shi Y. … Ma D. (Nat. Genet. 2013) 3

Products for HLA-DPB2 Gene

Sources for HLA-DPB2 Gene

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