Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HLA-DPA1 Gene

protein-coding   GIFtS: 57
GCID: GC06M033032

major histocompatibility complex, class II, DP alpha 1


(Previous symbol: HLA-DP1A)
 Explore 47 diseases affiliated with
HLA-DPA1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for HLA-DPA1    

Aliases
for HLA-DPA1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Major Histocompatibility Complex, Class II, DP Alpha 11 2     HLADP2 5
HLA-DP1A1 2 3     PLT12
DP(W3)2 3     HLA Class II Histocompatibility Antigen, DP Alpha 1 Chain2
DP(W4)2 3     HLA Class II Histocompatibility Antigen, DP Alpha Chain2
HLASB2 3     MHC Class II Antigen2
HLA-SB Alpha Chain2 3     MHC Class II HLA-DPA1 Antigen2
MHC Class II DP3-Alpha2 3     Primed Lymphocyte Test-12
MHC Class II DPA12 3     

External Ids:    HGNC: 49381   Entrez Gene: 31132   Ensembl: ENSG000002313897   OMIM: 1428805   UniProtKB: P200363   

Export aliases for HLA-DPA1 gene to outside databases

Previous GC identifers: GC06U990043 GC06M033029 GC06M033079 GC06M033140 GC06M032775


Summaries
for HLA-DPA1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for HLA-DPA1:
HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an
alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by
presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells
(APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5
exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the
transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain
the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. (provided by
RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: DPA1_HUMAN, P20036
Function: Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and
presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides
of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins
that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous
antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and
for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their
way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal
compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a
source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition
to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molecules and CD74
and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molecule that presents an
antigen, three MHC class II molecules (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the
ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen
processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a
small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM
via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molecules
until primary high affinity antigenic peptides are bound. The MHC II molecule bound to a peptide is then transported
to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by
HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal miroenvironment has been implicated in the
regulation of antigen loading into MHC II molecules, increased acidification produces increased proteolysis and
efficient peptide loading




Genomic Views
for HLA-DPA1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  NT_113891.2  NT_167244.1  NT_167245.1  NT_167246.1  NT_167247.1  
NT_167248.1  NT_167249.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HLA-DPA1 gene promoter:
         GR   NRSF form 1   p300   CUTL1   MIF-1   NRSF form 2   PPAR-alpha   STAT3   GR-alpha   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: HLA-DPA1 promoter sequence
   Search SABiosciences Chromatin IP Primers for HLA-DPA1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HLA-DPA1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p21.32   HGNC cytogenetic band: 6p21.3

HLA-DPA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HLA-DPA1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M033032:  view genomic region     (about GC identifiers)

Start:
 33,032,346 bp from pter      End:
 33,048,552 bp from pter
Size:
 16,207 bases      Orientation:
 minus strand

6/7 alternative locations (see all 7):
Chr6-,ALT_REF_LOCI_6 32,961,400-33,006,013      Chr6-,ALT_REF_LOCI_5 32,981,090-32,989,656      Chr6-,ALT_REF_LOCI_2 32,954,322-33,002,542     
Chr6-,ALT_REF_LOCI_3 33,010,288-33,030,358      Chr6-,ALT_REF_LOCI_1 33,015,768-33,033,082      Chr6-,ALT_REF_LOCI_4 33,109,993-33,118,577     

Proteins
for HLA-DPA1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: DPA1_HUMAN, P20036 (See protein sequence)
Recommended Name: HLA class II histocompatibility antigen, DP alpha 1 chain precursor  
Size: 260 amino acids; 29381 Da
Subunit: Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic
reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant
chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes
sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC
class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of
antigenic peptides
Subcellular location: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass
type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome
membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=The MHC
class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the
cell membrane for antigen presentation
Sequence caution: Sequence=AAC64233.1; Type=Erroneous gene model prediction; Sequence=AAD42927.1; Type=Erroneous gene
model prediction;
1 PDB 3D structure from and Proteopedia for HLA-DPA1:
3LQZ (3D)    
Secondary accessions: A9YWH7 B9UKH4 O19722 O46883 P01905 P79554 Q2Q060 Q2Q061 Q5EY03 Q5STP1 Q6DQK4
Q9BCQ1 Q9TPX3 Q9XS10

Explore the universe of human proteins at neXtProt for HLA-DPA1: NX_P20036

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P20036

    • HLA-DPA1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001229453.1  NP_001229454.1  NP_291032.2  

    ENSEMBL proteins: 
     ENSP00000393566   ENSP00000405500   ENSP00000412313   ENSP00000390929   ENSP00000398134  
     ENSP00000402872  
    Reactome Protein details: P20036
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: HLA-DPA1
    OriGene Custom Protein Services for HLA-DPA1 
    GenScript Custom Purified and Recombinant Proteins Services for HLA-DPA1
    Novus Biologicals HLA-DPA1 Protein
    Novus Biologicals HLA-DPA1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Uscn

    Gene Ontology (GO): 5/15 cellular component terms (GO ID links to tree view) (see all 15):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0005765lysosomal membrane TAS--
    GO:0005789endoplasmic reticulum membrane ----
    GO:0005794Golgi apparatus ----
    GO:0005886plasma membrane TAS--


    HLA-DPA1 for ontologies           About GeneDecksing



    HLA-DPA1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for HLA-DPA1 
    GenScript Custom Superior Antibodies Services for HLA-DPA1
    Novus Biologicals HLA-DPA1 Antibodies
    Search for Antibodies for HLA-DPA1 at Abcam  
    Browse Antibodies at Uscn
    Search ThermoFisher Antibodies for HLA-DPA1

    Assay Products for HLA-DPA1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for HLA-DPA1
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs and CLIAs at Uscn

    Protein Domains /
    Families
    for HLA-DPA1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HLA-DPA1 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR001003 MHC_II_a_N
     IPR011162 MHC_I/II-like_Ag-recog
     IPR013783 Ig-like_fold
     IPR014745 MHC_II_a/b_N
     IPR003597 Ig_C1-set

    Graphical View of Domain Structure for InterPro Entry P20036

    ProtoNet protein and cluster: P20036

    2 Blocks protein families:
    IPB001003 MHC Class II alpha chain
    IPB003597 Immunoglobulin C-type


    UniProtKB/Swiss-Prot: DPA1_HUMAN, P20036
    Similarity: Belongs to the MHC class II family
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain


    Function
    for HLA-DPA1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: DPA1_HUMAN, P20036
    Function: Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and
    presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides
    of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins
    that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous
    antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and
    for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their
    way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal
    compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a
    source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition
    to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molecules and CD74
    and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molecule that presents an
    antigen, three MHC class II molecules (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the
    ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen
    processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a
    small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM
    via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molecules
    until primary high affinity antigenic peptides are bound. The MHC II molecule bound to a peptide is then transported
    to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by
    HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal miroenvironment has been implicated in the
    regulation of antigen loading into MHC II molecules, increased acidification produces increased proteolysis and
    efficient peptide loading

         Genatlas biochemistry entry for HLA-DPA1:
    HLA-DP,alpha chain

    miRNA
    Products:            		 OriGene 3'-UTR Clone: HLA-DPA1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HLA-DPA1
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate HLA-DPA1:
    hsa-miR-877* hsa-miR-631 hsa-miR-3661
    SwitchGear 3'UTR luciferase reporter plasmid: HLA-DPA1 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    Browse OriGene 29mer shRNA kits
    OriGene siRNA: HLA-DPA1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HLA-DPA1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for HLA-DPA1

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HLA-DPA1
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HLA-DPA1 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: HLA-DPA1 (NM_033554)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HLA-DPA1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HLA-DPA1 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for HLA-DPA1
    Search LifeMap BioReagents cell lines for HLA-DPA1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HLA-DPA1

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032395MHC class II receptor activity NAS2461352


    HLA-DPA1 for ontologies           About GeneDecksing



    Pathways & Interactions
    for HLA-DPA1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/28 super-pathways (see all 28) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Allograft rejection
    8/10 pathways (see all 10)
    		Allograft rejection1.00
    		THC Differentiation Pathway0.39
    		Type I diabetes mellitus0.67
    		CTL Mediated Apoptosis0.38
    		Graft-versus-host disease0.63
    		Intestinal immune network for IgA production0.38
    		Autoimmune thyroid disease0.60
    		Viral myocarditis0.33
    2Transport of MHC II:Ii complex along Golgi to TGN
    		Transport of MHC II:Ii complex to plasma membrane1.00
    		Trafficking of nonameric complex in the endocytic pathway1.00
    		Transport of MHC II:Ii complex along Golgi to TGN1.00
    		Internalization of MHC II:Ii clathrin coated vesicle0.52
    		Insertion of MHC II:Ii complex in to the plasma membrane1.00
    3Translocation of ZAP-70 to Immunological synapse
    		Translocation of ZAP-70 to Immunological synapse1.00
    		PD-1 signaling0.76
    		Phosphorylation of CD3 and TCR zeta chains0.85
    		Generation of second messenger molecules0.64
    4ICos-ICosL Pathway in T-Helper Cell
    		ICos-ICosL Pathway in T-Helper Cell1.00
    		Calcium Mediated T-Cell Apoptosis0.31
    		CD28 Signaling in T-Helper Cell0.66
    5PKC-Theta Pathway
    		PKC-Theta Pathway1.00
    		ITK and TCR Signaling0.54
    		TCR Signaling0.68

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    5/6 EMD Millipore Pathways for HLA-DPA1 (see all 6)
        Immune response Antigen presentation by MHC class II
    G-protein signaling N-RAS regulation pathway
    Immune response IL-22 signaling pathway
    Immune response NFAT in immune response
    Immune response ICOS pathway in T-helper cell

    5/12 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for HLA-DPA1 (see all 12)
        THC Differentiation Pathway
    Calcium Mediated T-Cell Apoptosis
    IL-4 Pathway
    ICos-ICosL Pathway in T-Helper Cell
    CDC42 Pathway

    5/6 GeneGo (Thomson Reuters) Pathways for HLA-DPA1 (see all 6)
        Immune response Antigen presentation by MHC class II
    Immune response ICOS pathway in T-helper cell
    Immune response T cell receptor signaling pathway
    Immune response IL-22 signaling pathway
    G-protein signaling N-RAS regulation pathway

    5/20        Reactome Pathways for HLA-DPA1 (see all 20)
        Internalization of MHC II:Ii clathrin coated vesicle
    Costimulation by the CD28 family
    Transport of MHC II:Ii complex along Golgi to TGN
    Transport of MHC II:Ii complex to plasma membrane
    Transport of antigen loaded MHC II molecules to surface


    5/17         Kegg Pathways  (Kegg details for HLA-DPA1) (see all 17):
        Phagosome
    Cell adhesion molecules (CAMs)
    Antigen processing and presentation
    Intestinal immune network for IgA production
    Type I diabetes mellitus


    HLA-DPA1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HLA-DPA1

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for HLA-DPA1 (P200362, 3 ENSP000003935664) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CD74P042332, 3, ENSP000000095304MINT-72790 I2D: score=2 STRING: ENSP00000009530
    HLA-DPB1P044403, ENSP000004081464I2D: score=1 STRING: ENSP00000408146
    CD4P017303, ENSP000000116534I2D: score=2 STRING: ENSP00000011653
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002504antigen processing and presentation of peptide or polysaccharide antigen via MHC class II ----
    GO:0006955immune response NAS2461352
    GO:0019221cytokine-mediated signaling pathway TAS--
    GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II TAS--
    GO:0031295T cell costimulation TAS--


    HLA-DPA1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for HLA-DPA1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    HLA-DPA1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HLA-DPA1
    1 Novoseek chemical compound relationship for HLA-DPA1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    dpa 1 95 5 9154456 (3), 8225437 (1)

    Search CenterWatch for drugs/clinical trials and news about HLA-DPA1 / DPA1 

    Transcripts
    for HLA-DPA1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for HLA-DPA1 gene (3 alternative transcripts): 
    NM_001242524.1  NM_001242525.1  NM_033554.3  

    Unigene Cluster for HLA-DPA1:

    Major histocompatibility complex, class II, DP alpha 1
    Hs.347270  [show with all ESTs]
    Unigene Representative Sequence: NM_001242524
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000419277(uc003ocs.2 uc021ywg.1 uc021ywh.1) ENST00000479107(uc010juk.3)
    ENST00000437811 ENST00000448544 ENST00000453337 ENST00000476642 ENST00000463066
    ENST00000417724 ENST00000428995

    miRNA
    Products:             		 OriGene 3'-UTR Clone: HLA-DPA1
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HLA-DPA1
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate HLA-DPA1:
    hsa-miR-877* hsa-miR-631 hsa-miR-3661
    SwitchGear 3'UTR luciferase reporter plasmid: HLA-DPA1 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    Browse OriGene 29mer shRNA kits
    OriGene siRNA: HLA-DPA1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HLA-DPA1
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HLA-DPA1
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HLA-DPA1 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: HLA-DPA1 (NM_033554)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HLA-DPA1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HLA-DPA1 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HLA-DPA1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat HLA-DPA1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HLA-DPA1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HLA-DPA1

    Additional cDNA sequence: 

    AK292709.1 BC009956.2 M27487.1 X00457.1 

    24/35 DOTS entries (see all 35):

    DT.121402866  DT.95202456  DT.449635  DT.100838953  DT.95163813  DT.100830372  DT.95163821  DT.100838951 
    DT.95163812  DT.100838955  DT.95163819  DT.100045889  DT.121402704  DT.91970147  DT.95106210  DT.100855331 
    DT.95163816  DT.121402712  DT.121402724  DT.121402761  DT.121402790  DT.121402837  DT.121402842  DT.121402868 

    24/699 AceView cDNA sequences (see all 699):

    CD516536 BM767502 BG152603 CA426210 CA425192 BQ642196 BQ955105 BE765202 
    CA435547 BI769913 BQ446410 BQ890384 BQ057757 BQ056978 BM996250 CA308455 
    BQ062257 BX363746 AU139061 H66976 AI474920 BI517599 BU621846 BU617249 

    GeneLoc Exon Structure


    Expression
    for HLA-DPA1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HLA-DPA1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGAAAACTAC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    HLA-DPA1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Umbilical CordUmbilical VeinsUmbilical Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See HLA-DPA1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HLA-DPA1

    SOURCE GeneReport for Unigene cluster: Hs.347270
        SABiosciences Expression via Pathway-Focused PCR Array including HLA-DPA1: 
              Antigen Presenting Cells in human mouse rat

    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HLA-DPA1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat HLA-DPA1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HLA-DPA1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HLA-DPA1
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HLA-DPA1

    Orthologs
    for HLA-DPA1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for HLA-DPA1 gene from 2/4 species (see all 4)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    		 --
    		 59(a)
    54(a)
    		 many ↔ many
    many ↔ many
    		 GL343775.1(36865-38243)
    GL343809.1(2435-3996)
    zebrafish
    (Danio rerio)    		 Actinopterygii si:dkeyp-2h4.26
    si:zfos-2070c2.16
    (see all 10)    		 si:zfos-2070c2.1
    (see all 10)    		 31(a)
    30(a)
    (see all 10)    		 many ↔ many
    many ↔ many
    (see all 10)    		 8(37539907-37543263)
    8(37488525-37498906)


    ENSEMBL Gene Tree for HLA-DPA1 (if available)
    TreeFam Gene Tree for HLA-DPA1 (if available) 

    Paralogs
    for HLA-DPA1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HLA-DPA1 gene
    HLA-DRB52  HLA-DQA12  HLA-DQB12  HLA-DRA2  HLA-DOB2  HLA-DRB12  HLA-DMA2  HLA-DQB22  
    HLA-DOA2  ENSG000002489932  HLA-DMB2  HLA-DQA22  HLA-DPB12  
    18/41 SIMAP similar genes for HLA-DPA1 using alignment to 106 protein entries:     DPA1_HUMAN (see all proteins) (see all similar genes):
    HLA-DQA2    HLA-DRA1    HLA-DQA1/DRA    HLA-DQA1    DQ-A1    HLA-DRA
    HLA-DOA    DQA1-0103    HLA-DPB1    HLA-DQ3    HLA-DQB2    HLA-DPB
    HLA-DQB1    HLA-DQB    HLA-D    HLQ-DQB1    HLA-DRB1    B2M

    HLA-DPA1 for paralogs           About GeneDecksing



    Genomic Variants
    for HLA-DPA1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    UniProtKB/Swiss-Prot: DPA1_HUMAN, P20036
    Polymorphism: The following alleles of DPA1 are known: DPA1*01:03, DPA1*01:04, DPA1*01:05, DPA1*01:06, DPA1*01:07,
    DPA1*01:08, DPA1*01:09, DPA1*01:10, DPA1*02:01, DPA1*02:02, DPA1*02:03, DPA1*02:04, DPA1*03:01, DPA1*03:02,
    DPA1*03:03, DPA1*04:01 The sequence shown is that of DPA1*01:03


    10/988 NCBI SNPs in HLA-DPA1 are shown (see all 988)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1500377971,2
    		C,--33031917(+) TTTTT-/CCAATA 3 -- ds50010--------
    rs1131455171,2
    		C,--33031920(+) TTTCAG/ATAGTT 3 -- ds50011Minor allele frequency- A:0.00CSA 1
    rs2000914121,2
    		--33031920(+) TTCAA-/GTAGTT 3 -- ds50010--------
    rs728739461,2
    		C,--33031934(+) AGGAGC/TTTAAA 3 -- ds50015Minor allele frequency- T:0.49WA CSA NA EA 361
    rs668822831,2
    		C,--33031986(+) CACTTA/CACATG 3 -- ds50016Minor allele frequency- C:0.49WA CSA NA EA 363
    rs675146921,2
    		C,--33031994(+) ATGTAT/CAAGAA 3 -- ds50017Minor allele frequency- C:0.49WA NA CSA EA 365
    rs733979161,2
    		C,--33032013(+) CATTAT/CACTTC 3 -- ds50015Minor allele frequency- C:0.24WA CSA NA EA 361
    rs1819004191,2
    		--33032074(+) GTATGC/TTATAA 3 -- ds50010--------
    rs172208991,2
    		C,F,--33032096(+) ATTTTT/CACTTT 3 -- ds50017Minor allele frequency- C:0.46MN WA CSA NA EA 415
    rs1386186731,2
    		C,--33032122(+) AACTT-/AAAAAA 3 -- ds50010--------

    HapMap Linkage Disequilibrium report for HLA-DPA1 (33032346 - 33048552 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for HLA-DPA1
         3 CNVs: 69474 69477 59334
    Locus Specific Mutation Databases (LSDB): HLA-DPA1

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HLA-DPA1
    DNA2.0 Custom Variant and Variant Library Synthesis for HLA-DPA1

    Disorders / Diseases
    for HLA-DPA1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    HLA-DPA1 for disorders           About GeneDecksing

    OMIM gene information: 142880    OMIM disorders: --

    20/47 diseases for HLA-DPA1 (see all 47):    About MalaCards
    pre-eclampsia    severe pre-eclampsia    graft versus host disease    herpetic keratitis
    glanzmann's thrombasthenia    acute disseminated encephalomyelitis    intrahepatic cholestasis    intrahepatic cholestasis of pregnancy
    amyotrophic lateral sclerosis    lupus erythematosus    berylliosis    lateral sclerosis
    cutaneous leishmaniasis    systemic lupus erythematosus    cholestasis    celiac disease
    inflammatory bowel disease    keratitis    dilated cardiomyopathy    eclampsia

    2 Novoseek disease relationships for HLA-DPA1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    celiac disease 39.7 2 7576003 (1), 1676703 (1)
    lupus erythematosus systemic 17.7 4 8154937 (2), 2323107 (1)

    Genetic Association Database (GAD): HLA-DPA1
    Human Genome Epidemiology (HuGE) Navigator: HLA-DPA1 (45 documents)

    Export disorders for HLA-DPA1 gene to outside databases

    Publications
    for HLA-DPA1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HLA-DPA1 gene, integrated from 9 sources (see all 159):
    (articles sorted by number of sources associating them with HLA-DPA1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Isotypic and allotypic variation of human class II histocompatibility antigen alpha-chain genes. (PubMed id 6584734)1, 2, 3 Auffray C....Strominger J.L. (1984)
    2. [Studies on the association of human leukocyte antigen class II alleles with advanced hepatosplenic schistosomiasis japonica] (PubMed id 16042197)1, 4 Zhang J.H....Long X.C. (2005)
    3. Identification of HLA-DRPhebeta47 as the susceptibility marker of hypersensitivity to beryllium in individuals lacking the berylliosis-associated supratypic marker HLA-DPGlubeta69. (PubMed id 16098233)1, 4 Amicosante M....Saltini C. (2005)
    4. High-resolution sequence-based DPA1 typing identified two novel DPA1 alleles, DPA1*010303 and DPA1*0303, from a Kenyan population. (PubMed id 15663751)1, 2 Luo M.... Plummer F.A. (2005)
    5. HLA-DPA1 promoter haplotypes are differently distributed in southern Chinese ethnic groups. (PubMed id 15713216)1, 4 Liu X....Xu A. (2005)
    6. Role of HLA class II alleles in susceptibility to and protection from localized cutaneous leishmaniasis. (PubMed id 15041165)1, 4 Olivo-Diaz A....Gorodezky C. (2004)
    7. Genetic polymorphism and linkage disequilibrium of the HLA-DP region in Basques from Navarre (Spain). (PubMed id 15304007)1, 4 Perez-Miranda A.M....Pena J.A. (2004)
    8. HLA-DP polymorphism in Venezuelan Amerindians. (PubMed id 15603877)1, 4 Gendzekhadze K....Layrisse Z. (2004)
    9. Associations between human leukocyte antigen (HLA) alleles and very high levels of measles antibody following vaccination. (PubMed id 15121303)1, 4 Ovsyannikova I.G....Poland G.A. (2004)
    10. Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome. (PubMed id 15191952)1, 4 Flomenberg N....Weisdorf D. (2004)

    External Searches for HLA-DPA1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing HLA-DPA1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3113 HGNC: 4938 AceView: HLA-DPA1 Ensembl:ENSG00000231389 euGenes: HUgn3113
    ECgene: HLA-DPA1 Kegg: 3113 H-InvDB: HLA-DPA1

    Other Databases showing HLA-DPA1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing HLA-DPA1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HLA-DPA1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for HLA-DPA1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for HLA-DPA1 gene:
    Search GeneIP for patents involving HLA-DPA1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for HLA-DPA1 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   Browse OriGene shRNA RFPs  
     Browse OriGene 29mer shRNA kits in GFP-retroviral vector   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HLA-DPA1  
     OriGene Protein Over-expression Lysate for HLA-DPA1   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for HLA-DPA1   OriGene 3'-UTR Clone for HLA-DPA1  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HLA-DPA1   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HLA-DPA1  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for HLA-DPA1   OriGene Custom Protein Services for HLA-DPA1  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HLA-DPA1
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HLA-DPA1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HLA-DPA1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HLA-DPA1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HLA-DPA1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HLA-DPA1
     GenScript Custom Purified and Recombinant Proteins Services for HLA-DPA1 GenScript cDNA clones with any tag delivered in your preferred vector for HLA-DPA1
     GenScript Custom Assay Services for HLA-DPA1 GenScript Custom Superior Antibodies Services for HLA-DPA1
     GenScript Custom overexpressing Cell Line Services for HLA-DPA1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in HLA-DPA1 promoter
     Search Chromatin IP Primers for HLA-DPA1
     RT2 qPCR Primer Assay in human, mouse / rat HLA-DPA1
     GNC Network for HLA-DPA1
     SABiosciences PCR Arrays including human, mouse / rat HLA-DPA1
     Search Tocris compounds for HLA-DPA1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     HLA-DPA1 antibodies
     HLA-DPA1 proteins
     HLA-DPA1 lysates
     Search for Antibodies for HLA-DPA1 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for HLA-DPA1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse ELISAs, CLIAs, Proteins, and Antibodies at Uscn
     Search LifeMap BioReagents cell lines for HLA-DPA1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HLA-DPA1
     SwitchGear 3'UTR luciferase reporter plasmids for HLA-DPA1
     SwitchGear Promoter luciferase reporter plasmids for HLA-DPA1
     Search ThermoFisher Antibodies for HLA-DPA1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HLA-DPA1
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      HLA-DPA1 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4