Aliases for HLA-DOA Gene
Aliases for HLA-DOA Gene
External Ids for HLA-DOA Gene
- HGNC: 4936
- Entrez Gene: 3111
- Ensembl: ENSG00000204252
- OMIM: 142930
- UniProtKB: P06340
Previous HGNC Symbols for HLA-DOA Gene
- HLA-DZA
- HLA-DNA
Previous GeneCards Identifiers for HLA-DOA Gene
- GC06M032976
- GC06M033020
- GC06M033081
- GC06M032971
- GC06M032714
Summaries for HLA-DOA Gene
-
HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008]
GeneCards Summary for HLA-DOA Gene
HLA-DOA (Major Histocompatibility Complex, Class II, DO Alpha) is a Protein Coding gene. Diseases associated with HLA-DOA include Keshan Disease. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and CTLA4 Signaling. GO annotations related to this gene include MHC class II protein complex binding and MHC class II receptor activity. An important paralog of this gene is HLA-DQA1.
UniProtKB/Swiss-Prot for HLA-DOA Gene
-
Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HLA-DOA Gene
Genomics for HLA-DOA Gene
Regulatory Elements for HLA-DOA Gene
Enhancers for HLA-DOA Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HLA-DOA on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the HLA-DOA gene promoter:
Regulatory Element Products
Genomic Location for HLA-DOA Gene
- Chromosome:
- 6
- Start:
- 33,004,178 bp from pter
- End:
- 33,009,612 bp from pter
- Size:
- 5,435 bases
- Orientation:
- Minus strand
Genomic View for HLA-DOA Gene
Genes around HLA-DOA on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p21.32 by Ensembl
- 6p21.32 by Entrez Gene
- 6p21.32 by HGNC
HLA-DOA Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HLA-DOA Gene
Proteins for HLA-DOA Gene
-
Protein details for HLA-DOA Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P06340-DOA_HUMAN
- Recommended name:
- HLA class II histocompatibility antigen, DO alpha chain
- Protein Accession:
- P06340
- Q58HU0
- Q58HU1
- Q5STC7
- Q9TQC6
- Q9TQC7
- Q9TQC8
- Q9TQC9
- Q9TQD0
- Q9TQD1
- Q9TQD2
- Q9TQD3
Protein attributes for HLA-DOA Gene
- Size:
- 250 amino acids
- Molecular mass:
- 27599 Da
- Quaternary structure:
-
- Heterodimer of an alpha chain (DOA) and a beta chain (DOB). Forms a heterotetrameric complex with an HLA-DM molecule during intracellular transport in endosomal/lysosomal compartments in B-cells.
Protein Expression for HLA-DOA Gene
Post-translational modifications for HLA-DOA Gene
Other Protein References for HLA-DOA Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for HLA-DOA
-
Abcam antibodies for HLA-DOA
- Invitrogen Antibodies for HLA-DOA
- antibodies-online Antibodies for HLA-DOA: See all 28
- GeneTex HLA-DOA antibody for HLA-DOA
-
Santa Cruz Biotechnology (SCBT) Antibodies for HLA-DOA
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HLA-DOA
- Origene Custom Protein Services for HLA-DOA
- ProSpec Recombinant Proteins for HLA-DOA
- antibodies-online Proteins for HLA-DOA: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Proteins for HLA-DOA
-
Abcam proteins for HLA-DOA
Assay Products
No data available for DME Specific Peptides for HLA-DOA Gene
Domains & Families for HLA-DOA Gene
Gene Families for HLA-DOA Gene
Protein Domains for HLA-DOA Gene
Suggested Antigen Peptide Sequences for HLA-DOA Gene
- GenScript: Design optimal peptide antigens:
-
- Major histocompatibility complex, class II, DO alpha (A2ALI8_HUMAN)
- Major histocompatibility complex, class II, DO alpha (A9R9R2_HUMAN)
- Major histocompatibility complex, class II, DO alpha (B0V049_HUMAN)
- Major histocompatibility complex, class II, DO alpha (B0V2A6_HUMAN)
- Major histocompatibility complex, class II, DO alpha (B1ATE8_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P06340- Family:
-
- Belongs to the MHC class II family.
Function for HLA-DOA Gene
Molecular function for HLA-DOA Gene
- UniProtKB/Swiss-Prot Function:
- Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0023026 | MHC class II protein complex binding | IDA | 22733780 |
| GO:0032395 | MHC class II receptor activity | TAS | 3000765 |
Phenotypes for HLA-DOA Gene
- MGI mutant phenotypes for HLA-DOA:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for HLA-DOA:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences ready-to-package AAV shRNAs for HLA-DOA gene
- Search ViGene Biosciences for HLA-DOA
CRISPR Products
- Browse CRISPR knockouts for HLA-DOA
-
Santa Cruz Biotechnology (SCBT) CRISPR for HLA-DOA
- GenScript: Design CRISPR guide RNA sequences for HLA-DOA
miRNA for HLA-DOA Gene
- miRTarBase miRNAs that target HLA-DOA
-
- hsa-mir-6809-3p (MIRT448002)
- hsa-mir-6833-3p (MIRT448004)
- hsa-mir-4768-5p (MIRT448005)
- hsa-mir-3191-5p (MIRT448006)
- hsa-mir-6770-5p (MIRT448007)
- hsa-mir-1253 (MIRT448008)
- hsa-mir-6846-3p (MIRT448009)
- hsa-mir-6859-3p (MIRT448010)
- hsa-mir-6761-5p (MIRT448011)
- hsa-mir-4251 (MIRT448012)
- hsa-mir-4329 (MIRT448013)
- hsa-mir-4653-5p (MIRT448014)
- hsa-mir-3921 (MIRT448015)
- hsa-mir-301b-5p (MIRT448016)
- hsa-mir-301a-5p (MIRT448017)
- hsa-mir-146a-3p (MIRT448018)
- hsa-mir-4511 (MIRT448019)
- hsa-mir-130b-5p (MIRT450608)
- hsa-mir-3915 (MIRT491496)
- hsa-mir-6734-5p (MIRT491497)
- hsa-mir-7704 (MIRT491498)
- hsa-mir-6738-5p (MIRT491499)
- hsa-mir-7160-5p (MIRT491500)
- hsa-mir-5194 (MIRT491501)
- hsa-mir-1914-3p (MIRT491502)
- hsa-mir-3184-5p (MIRT491503)
- hsa-mir-423-5p (MIRT491504)
- hsa-mir-3928-3p (MIRT491505)
- hsa-mir-6732-5p (MIRT491507)
miRNA Products
- Search ViGene Biosciences for HLA-DOA
Inhibitory RNA Products
-
ViGene Biosciences ready-to-package AAV shRNAs for HLA-DOA gene
Clone Products
- Sino Biological Human cDNA Clone for HLA-DOA
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for HLA-DOA
-
ViGene Biosciences adenoviral particle packaged cDNA for HLA-DOA gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HLA-DOA gene
- Search ViGene Biosciences for HLA-DOA
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HLA-DOA Gene
Localization for HLA-DOA Gene
Subcellular locations from UniProtKB/Swiss-Prot for HLA-DOA Gene
- Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| lysosome | 5 |
| endosome | 5 |
| extracellular | 2 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005764 | lysosome | IEA | -- |
| GO:0005765 | lysosomal membrane | TAS | -- |
| GO:0005768 | endosome | IEA | -- |
| GO:0005886 | plasma membrane | TAS | 3000765 |
| GO:0010008 | endosome membrane | IEA | -- |
Pathways & Interactions for HLA-DOA Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Allograft rejection |
.44
|
|
| 2 | Th17 cell differentiation | ||
| 3 | ICos-ICosL Pathway in T-Helper Cell | ||
| 4 | TCR Signaling (Qiagen) |
.68
|
|
| 5 | Immune response NFAT in immune response | ||
Pathways by source for HLA-DOA Gene
1 BioSystems pathway for HLA-DOA Gene
3 Reactome pathways for HLA-DOA Gene
23 KEGG pathways for HLA-DOA Gene
6 GeneGo (Thomson Reuters) pathways for HLA-DOA Gene
12 Qiagen pathways for HLA-DOA Gene
Interacting Proteins for HLA-DOA Gene
Selected Interacting proteins:
ENSP00000229829
P06340-DOA_HUMAN
for HLA-DOA Gene via
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002504 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | IEA | -- |
| GO:0002587 | negative regulation of antigen processing and presentation of peptide antigen via MHC class II | IDA | 22733780 |
| GO:0006955 | immune response | IEA | -- |
| GO:0007165 | signal transduction | IEA | -- |
| GO:0019882 | antigen processing and presentation | IEA | -- |
No data available for SIGNOR curated interactions for HLA-DOA Gene
Transcripts for HLA-DOA Gene
mRNA/cDNA for HLA-DOA Gene
- (1) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (121) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HLA-DOA Gene
CRISPR Products
- Browse CRISPR knockouts for HLA-DOA
-
Santa Cruz Biotechnology (SCBT) CRISPR for HLA-DOA
- GenScript: Design CRISPR guide RNA sequences for HLA-DOA
miRNA Products
- Search ViGene Biosciences for HLA-DOA
Inhibitory RNA Products
-
ViGene Biosciences ready-to-package AAV shRNAs for HLA-DOA gene
Clone Products
- Sino Biological Human cDNA Clone for HLA-DOA
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for HLA-DOA Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Neural Tube (Nervous System)
- Inner Cell Mass (Early Embryonic Tissues)
-
Blood (Hematopoietic System)
- Mature B-Cells Peripheral Blood
- Brain (Nervous System)
- Umbilical Cord (Extraembryonic Tissues)
- Bone (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for HLA-DOA Gene
This gene is overexpressed in Spleen (x5.1).
This gene is overexpressed in Blymphocyte (38.0), Lymph node (17.0), and Monocytes (13.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for HLA-DOA Gene
- Elite partner
SOURCE GeneReport for Unigene cluster for HLA-DOA Gene:
Hs.631991Evidence on tissue expression from TISSUES for HLA-DOA Gene
- Lung(4.2)
- Blood(2.1)
Primer Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HLA-DOA Gene
Orthologs for HLA-DOA Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HLA-DOA 35 |
|
OneToOne | |
| LOC471979 34 |
|
||||
| dog (Canis familiaris) |
Mammalia | DLA-DOA 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | BOLA-DOA 34 |
|
||
| BOLA-DNA 35 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | RT1-DOa 34 |
|
||
| mouse (Mus musculus) |
Mammalia | H2-Oa 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| zebrafish (Danio rerio) |
Actinopterygii | si:busm1-48c11.3 35 |
|
ManyToMany |
- Species where no ortholog for HLA-DOA was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for HLA-DOA Gene
Paralogs for HLA-DOA Gene
(25) SIMAP similar genes for HLA-DOA Gene using alignment to 3 proteins:
Variants for HLA-DOA Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for HLA-DOA Gene
- DOA_HUMAN-P06340
- The following alleles of DOA are known: DOA*01:01, DOA*01:02 and DOA*01:03. The sequence shown is that of DOA*01:01.
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000345977 | -- | 33,008,774(+) | CTCAA(A/G)GCATT | intron-variant | |
| rs1000717381 | -- | 33,008,868(+) | CTTCC(A/G)TAACT | intron-variant | |
| rs1002083573 | -- | 33,004,625(+) | ACACC(A/G)CTAAC | utr-variant-3-prime | |
| rs1002460930 | -- | 33,010,661(+) | AGGGA(A/T)GCCTA | upstream-variant-2KB | |
| rs1002749401 | -- | 33,007,079(+) | CTGCA(C/T)CTGGG | splice-donor-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1024429 | CNV | loss | 25217958 |
| nsv1073969 | CNV | deletion | 25765185 |
| nsv1112900 | CNV | deletion | 24896259 |
| nsv1119076 | CNV | deletion | 24896259 |
| nsv483081 | CNV | loss | 15286789 |
| nsv602818 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
77.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.14;
51.47% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HLA-DOA Gene
Disorders for HLA-DOA Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| keshan disease |
|
|
Search HLA-DOA in MalaCards
View complete list of genes associated with diseases
Relevant External Links for HLA-DOA
No data available for UniProtKB/Swiss-Prot and Genatlas for HLA-DOA Gene
Publications for HLA-DOA Gene
- Limited polymorphism in the HLA-DOA gene. (PMID: 10323340) Naruse T.K. … Inoko H. (Tissue Antigens 1999) 3 4 22 64
- The HLA-DNA (DZA) gene is correctly expressed as a 1.1 kb mature mRNA transcript. (PMID: 2370084) Young J.A. … Trowsdale J. (Immunogenetics 1990) 2 3 4 64
- New gene functions in megakaryopoiesis and platelet formation. (PMID: 22139419) Gieger C. … Soranzo N. (Nature 2011) 3 46 64
- Genetic association of htSNPs across the major histocompatibility complex with rheumatoid arthritis in an African-American population. (PMID: 19741715) Reynolds R.J. … Bridges S.L. (Genes Immun. 2010) 3 46 64
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 46 64
Products for HLA-DOA Gene
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- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HLA-DOA
- Origene Custom Protein Services for HLA-DOA
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for HLA-DOA in any vector
- GenScript Custom Purified and Recombinant Proteins Services for HLA-DOA
- GenScript Custom Assay Services for HLA-DOA
- GenScript Custom overexpressing Cell Line Services for HLA-DOA
- GenScript: Design CRISPR guide RNA sequences for HLA-DOA
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for HLA-DOA
- Novus Biologicals proteins and lysates for HLA-DOA
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for HLA-DOA
- Abcam proteins for HLA-DOA
- Search for Assays for HLA-DOA at Abcam
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- ProSpec Recombinant Proteins for HLA-DOA
- antibodies-online Antibodies for HLA-DOA: See all 28
- Search antibodies-online for kits
- antibodies-online Proteins for HLA-DOA: See all 3
- Search antibodies-online for peptides
- GeneTex HLA-DOA antibody for HLA-DOA
- Search GeneTex for Proteins for HLA-DOA
- ViGene Biosciences adenoviral particle packaged cDNA for HLA-DOA gene
- ViGene Biosciences ready-to-package AAV shRNAs for HLA-DOA gene
- Search ViGene Biosciences for HLA-DOA
- Santa Cruz Biotechnology (SCBT) Antibodies for HLA-DOA
- Search Santa Cruz Biotechnology (SCBT) for HLA-DOA siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HLA-DOA
- Horizon Cell Lines for HLA-DOA
- Cyagen custom Knockout/knockin (KOKI) mouse models for HLA-DOA
- VectorBuilder custom plasmid, inducible vectors for HLA-DOA
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HLA-DOA
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HLA-DOA Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
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- (122) diseasecard
- (123) NIH Rare Diseases
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- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
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- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer