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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HKDC1 Gene

protein-coding   GIFtS: 52
GCID: GC10P070980

hexokinase domain containing 1
 Explore 4 diseases affiliated with
HKDC1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for HKDC1    

Aliases
for HKDC1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Hexokinase Domain Containing 11 2     FLJ377671
Hexokinase Domain-Containing Protein 12 3     Putative Hexokinase HKDC12
EC 2.7.1.13 8     EC 2.7.18
FLJ227611     

External Ids:    HGNC: 233021   Entrez Gene: 802012   Ensembl: ENSG000001565107   UniProtKB: Q2TB903   

Export aliases for HKDC1 gene to outside databases

Previous GC identifers: GC10U900457 GC10P070651 GC10P064980


Summaries
for HKDC1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
  --

Genomic Views
for HKDC1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.1  NT_030059.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HKDC1 gene promoter:
         COUP-TF1   GR   C/EBPbeta   GR-beta   COUP   CUTL1   HNF-4alpha1   GATA-1   COUP-TF   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: HKDC1 promoter sequence
   Search SABiosciences Chromatin IP Primers for HKDC1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HKDC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.1   Ensembl cytogenetic band:  10q22.1   HGNC cytogenetic band: 10q22.1

HKDC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HKDC1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P070980:  view genomic region     (about GC identifiers)

Start:
 70,980,059 bp from pter      End:
 71,027,315 bp from pter
Size:
 47,257 bases      Orientation:
 plus strand

Proteins
for HKDC1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: HKDC1_HUMAN, Q2TB90 (See protein sequence)
Recommended Name: Putative hexokinase HKDC1  
Size: 917 amino acids; 102545 Da
Sequence caution: Sequence=AAH21278.1; Type=Frameshift; Positions=457; Sequence=BAB15478.1; Type=Frameshift;
Positions=345;
Secondary accessions: B5MDN9 Q2TB91 Q5VTC7 Q7Z373 Q8WU37 Q96EH2 Q9H5Y9
Alternative splicing: 3 isoforms:  Q2TB90-1   Q2TB90-2   Q2TB90-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for HKDC1: NX_Q2TB90

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q2TB90

    • 4/23 DME Specific Peptides for HKDC1 (Q2TB90) (see all 23)
     DIRTEFD  PDGTEKG  EWGAFGD  TMMTCGY 

    HKDC1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_079406.3  
    ENSEMBL proteins: 
     ENSP00000346643   ENSP00000378521  

    Human Recombinant Protein Products: 
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    Novus Biologicals HKDC1 Proteins
    Novus Biologicals HKDC1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for HKDC1

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005739mitochondrion IDA--
    GO:0005829cytosol IBA--


    HKDC1 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for HKDC1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HKDC1 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR019807 Hexokinase_CS
     IPR001312 Hexokinase
     IPR022672 Hexokinase_N
     IPR022673 Hexokinase_C

    Graphical View of Domain Structure for InterPro Entry Q2TB90

    ProtoNet protein and cluster: Q2TB90

    UniProtKB/Swiss-Prot: HKDC1_HUMAN, Q2TB90
    Similarity: Belongs to the hexokinase family


    Function
    for HKDC1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: HKDC1_HUMAN, Q2TB90
    Catalytic activity: ATP + D-hexose = ADP + D-hexose 6-phosphate

    Enzyme Numbers (IUBMB): EC 2.7.1.11 2 EC 2.7.12

    miRNA
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate HKDC1:
    hsa-miR-185* hsa-miR-1243 hsa-miR-876-5p hsa-miR-551b* hsa-miR-3167 hsa-miR-3144-3p
    SwitchGear 3'UTR luciferase reporter plasmid: HKDC1 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HKDC1 (see all 3)
    OriGene siRNA: HKDC1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HKDC1

    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for HKDC1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HKDC1

    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004340glucokinase activity IBA--
    GO:0004396hexokinase activity ----
    GO:0005524ATP binding IEA--
    GO:0008865fructokinase activity IBA--
    GO:0019158mannokinase activity IBA--


    HKDC1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for HKDC1:
     Increased cell death HMECs cel 


    Pathways & Interactions
    for HKDC1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/12 super-pathways (see all 12) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1GDP-glucose biosynthesis
    		glucose and glucose-1-phosphate degradation1.00
    		trehalose degradation II (trehalase)0.29
    		GDP-glucose biosynthesis1.00
    2Carbohydrate digestion and absorption
    		Carbohydrate digestion and absorption1.00
    3Type II diabetes mellitus
    		Type II diabetes mellitus1.00
    4Butirosin and neomycin biosynthesis
    		Butirosin and neomycin biosynthesis1.00
    5Amino sugar and nucleotide sugar metabolism
    		Amino sugar and nucleotide sugar metabolism1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    4 BioSystems Pathways for HKDC1 
        GDP-glucose biosynthesis
    UDP-N-acetyl-D-galactosamine biosynthesis II
    trehalose degradation II (trehalase)
    glucose and glucose-1-phosphate degradation


    5/10         Kegg Pathways  (Kegg details for HKDC1) (see all 10):
        Glycolysis / Gluconeogenesis
    Fructose and mannose metabolism
    Galactose metabolism
    Starch and sucrose metabolism
    Amino sugar and nucleotide sugar metabolism

    UniProtKB/Swiss-Prot: HKDC1_HUMAN, Q2TB90
    Pathway: Carbohydrate metabolism; hexose metabolism


    HKDC1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HKDC1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/49 Interacting proteins for HKDC1 (ENSP000003466434) via UniProtKB, MINT, STRING, and/or I2D (see all 49)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    C12orf5ENSP000001792594STRING: ENSP00000179259
    GPIENSP000003488774STRING: ENSP00000348877
    MPIENSP000003183184STRING: ENSP00000318318
    PFKFB3ENSP000003691004STRING: ENSP00000369100
    PFKLENSP000002698484STRING: ENSP00000269848
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001678cellular glucose homeostasis IBA--
    GO:0006096glycolysis IBA--
    GO:0051156glucose 6-phosphate metabolic process IBA--


    HKDC1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for HKDC1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HKDC1
    Search CenterWatch for drugs/clinical trials and news about HKDC1 

    Transcripts
    for HKDC1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for HKDC1 gene: 
    NM_025130.3  

    Unigene Cluster for HKDC1:

    Hexokinase domain containing 1
    Hs.522988  [show with all ESTs]
    Unigene Representative Sequence: NM_025130
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000354624(uc001jpf.4 uc010qje.2 uc009xqb.3) ENST00000486754
    ENST00000488706 ENST00000470920 ENST00000395086

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HKDC1
    6 QIAGEN miScript miRNA Assays for microRNAs that regulate HKDC1:
    hsa-miR-185* hsa-miR-1243 hsa-miR-876-5p hsa-miR-551b* hsa-miR-3167 hsa-miR-3144-3p
    SwitchGear 3'UTR luciferase reporter plasmid: HKDC1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HKDC1 (see all 3)
    OriGene siRNA: HKDC1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HKDC1
    Clone
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    GenScript: all cDNA clones in your preferred vector: HKDC1 (NM_025130)
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HKDC1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HKDC1

    Additional cDNA sequence: 

    AK026414.1 AK095086.1 AK291024.1 AK303408.1 BC012337.1 BC021278.2 BC069201.1 BC110504.1 
    BC110505.2 

    6 DOTS entries:

    DT.92418174  DT.101980253  DT.65287645  DT.102824413  DT.121282699  DT.75108663 

    24/71 AceView cDNA sequences (see all 71):

    BG326941 BQ686849 AK026414 BC012337 BU621064 BC069201 BX098625 AA877626 
    CA391830 AW271679 BQ188285 AK095086 BU736574 BQ949965 AW194769 BM715632 
    BC021278 AI492487 BX093628 AI380397 AA494373 AI339520 AV724583 BG386920 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for HKDC1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20
    SP1:                                -                 -                                                                             -               
    SP2:                                                  -                                                                                             
    SP3:                                                                                                                                                
    SP4:                                                                                                                                                


    ECgene alternative splicing isoforms for HKDC1

    Expression
    for HKDC1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HKDC1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGGTGGGGTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    HKDC1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    10/11 LifeMap In Vivo Development Anatomical Compartments/Cells (see all 11) 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Gut TubeHindgutHindgut Endoderm CellsEndoderm
    Gut TubeMidgutMidgut Endoderm CellsEndoderm
    Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor CellsMotor Neurons
    BrainChoroid PlexusBrain
    EyeRetinaEye
    Gut TubeHindgutGut Tube
    Gut TubeMidgutGut Tube
    LiverLiver LobuleLiver
    Neural TubeMesencephalic Ventricular ZoneNeural Tube
    Neural TubeMetencephalonNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Extraembryonic endoderm-like cells (Generation of extrae...)

    See HKDC1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HKDC1

    SOURCE GeneReport for Unigene cluster: Hs.522988
        SABiosciences Custom PCR Arrays for HKDC1
    Primer
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    In Situ
    Assay Products:     
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    Orthologs
    for HKDC1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for HKDC1 gene from 7/24 species (see all 24)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves HKDC11 hexokinase domain containing 1 75.42(n)
    84.62(a)    		   423698  XM_421579.3  XP_421579.2 
    lizard
    (Anolis carolinensis)    		 Reptilia HKDC16
    		 --
    		 81(a)
    		 1 ↔ 1
    		 GL343215.1(2056025-2079157)
    zebrafish
    (Danio rerio)    		 Actinopterygii hkdc11 hexokinase domain containing 1 69.94(n)
    75.25(a)    		   321224  NM_001115125.1  NP_001108597.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Hex-C6
    Hex-t26
    (see all 4)    		 Hex-t2
    (see all 4)    		 42(a)
    39(a)
    (see all 4)    		 many ↔ many
    many ↔ many
    (see all 4)    		 2R(11106342-11107917)
    3R(22276374-22278049)
    worm
    (Caenorhabditis elegans)    		 Secernentea F14B4.26
    Y77E11A.16
    (see all 3)    		 --
    		 42(a)
    35(a)
    (see all 3)    		 many ↔ many
    many ↔ many
    (see all 3)    		 I(9271436-9278681)
    IV(1497629-1509967)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons HXK21 hexokinase 2 44.52(n)
    39.19(a)    		   816505  NM_127544.2  NP_179576.1 
    rice
    (Oryza sativa)    		 Liliopsida Os01g07425001 hypothetical protein 48.56(n)
    41.26(a)    		   4326547  NM_001050749.1  NP_001044214.1 


    ENSEMBL Gene Tree for HKDC1 (if available)
    TreeFam Gene Tree for HKDC1 (if available) 

    Paralogs
    for HKDC1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HKDC1 gene
    HK32  HK22  HK12  GCK2  
    5 SIMAP similar genes for HKDC1 using alignment to 1 protein entry:     HKDC1_HUMAN:
    HK1    HK2    DKFZp686M1669    GCK    HK3

    HKDC1 for paralogs           About GeneDecksing



    Genomic Variants
    for HKDC1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/58 NCBI SNPs in HKDC1 are shown (see all 58)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 10 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs109986791,2
    		C,F,H,--65024616(+) ATATAC/TCCTGC 1 -- int128Minor allele frequency- T:0.06NS EA NA 2942
    rs801264971,2
    		--65025021(+) CTCGGC/TTTCTA 1 -- int10--------
    rs109986801,2
    		F,--65025504(+) GAAGAT/CGCATC 1 -- int11Minor allele frequency- C:0.02NA 120
    rs786099041,2
    		C,--65025559(+) ATTCAA/GTCTGA 1 -- int14Minor allele frequency- G:0.07NA WA EA 360
    rs792078941,2
    		F,--65025741(+) CACACG/AGGGCT 1 -- int11Minor allele frequency- A:0.03WA 118
    rs1123364831,2
    		C,--65025813(+) CTTGAG/CCCCAG 1 -- int13Minor allele frequency- C:0.06NA EA 242
    rs757442331,2
    		F,--65026030(+) ACCCTG/AGGCAA 1 -- int11Minor allele frequency- A:0.02WA 118
    rs37406011,2
    		C,--65026423(+) AGAGAC/GCAATG 1 -- ut31 ese35Minor allele frequency- G:0.06EA NA WA 1850
    rs118174581,2
    		C,F,H,--65027210(+) ATGGAA/TTAAGG 1 -- int16Minor allele frequency- T:0.02NS EA NA WA 532
    rs785080561,2
    		C,--65027224(+) GCAGAG/ATCAGA 1 -- int14Minor allele frequency- A:0.06NA WA EA 360

    HapMap Linkage Disequilibrium report for HKDC1 (70980059 - 71027315 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for HKDC1
         1 CNV: 100975
         3 Indels: 61034 44775 42764

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    Disorders / Diseases
    for HKDC1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    HKDC1 for disorders           About GeneDecksing

    4 diseases for HKDC1:    About MalaCards
    amebiasis    alzheimer's disease    malaria    alcoholism

    Human Genome Epidemiology (HuGE) Navigator: HKDC1 (4 documents)

    Export disorders for HKDC1 gene to outside databases

    Publications
    for HKDC1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HKDC1 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with HKDC1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    3. The global gene-expression profiles of U-937 human mac rophages treated with Tat peptide and Tat-FITC conjugate. (PubMed id 22632162)1 Lin C.W....Jan M.S. (2012)
    4. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    7. Investigation of genetic susceptibility factors for h uman longevity - A targeted nonsynonymous SNP study. (PubMed id 20800603)1 Flachsbart F....Nebel A. (2010)
    8. Case-control genome-wide association study of attenti on-deficit/hyperactivity disorder. (PubMed id 20732627)1 Neale B.M....Biederman J. (2010)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)

    External Searches for HKDC1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing HKDC1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80201 HGNC: 23302 AceView: FLJ22761 Ensembl:ENSG00000156510 euGenes: HUgn80201
    ECgene: HKDC1 Kegg: 80201 H-InvDB: HKDC1

    Other Databases showing HKDC1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing HKDC1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HKDC1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for HKDC1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for HKDC1 gene:
    Search GeneIP for patents involving HKDC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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