Aliases for HJURP Gene
External Ids for HJURP Gene
Previous GeneCards Identifiers for HJURP Gene
GeneCards Summary for HJURP Gene
HJURP (Holliday Junction Recognition Protein) is a Protein Coding gene. Diseases associated with HJURP include lung cancer. Among its related pathways are Cell Cycle, Mitotic and Packaging Of Telomere Ends. GO annotations related to this gene include histone binding.
UniProtKB/Swiss-Prot for HJURP Gene
Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.