Aliases for HJURP Gene
External Ids for HJURP Gene
Previous GeneCards Identifiers for HJURP Gene
GeneCards Summary for HJURP Gene
HJURP (Holliday Junction Recognition Protein) is a Protein Coding gene. Diseases associated with HJURP include Fibrillary Astrocytoma. Among its related pathways are Chromosome Maintenance and Chromatin Regulation / Acetylation. GO annotations related to this gene include identical protein binding and histone binding.
UniProtKB/Swiss-Prot for HJURP Gene
Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.