Aliases for HIVEP2 Gene
External Ids for HIVEP2 Gene
This gene encodes a member of a family of closely related, large, zinc finger-containing transcription factors. The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth, development and metastasis. The protein contains the ZAS domain comprised of two widely separated regions of zinc finger motifs, a stretch of highly acidic amino acids and a serine/threonine-rich sequence. [provided by RefSeq, Nov 2012]
GeneCards Summary for HIVEP2 Gene
HIVEP2 (Human Immunodeficiency Virus Type I Enhancer Binding Protein 2) is a Protein Coding gene. An important paralog of this gene is HIVEP1.
UniProtKB/Swiss-Prot for HIVEP2 Gene
This protein specifically binds to the DNA sequence 5-GGGACTTTCC-3 which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon-beta genes. It may act in T-cell activation