Aliases for HIVEP1 Gene
Aliases for HIVEP1 Gene
External Ids for HIVEP1 Gene
- HGNC: 4920
- Entrez Gene: 3096
- Ensembl: ENSG00000095951
- OMIM: 194540
- UniProtKB: P15822
Previous HGNC Symbols for HIVEP1 Gene
- ZNF40
Previous GeneCards Identifiers for HIVEP1 Gene
- GC06P012070
- GC06P012120
- GC06P011947
Summaries for HIVEP1 Gene
-
This gene encodes a transcription factor belonging to the ZAS family, members of which are large proteins that contain a ZAS domain - a modular protein structure consisting of a pair of C2H2 zinc fingers with an acidic-rich region and a serine/threonine-rich sequence. These proteins bind specifically to the DNA sequence motif, GGGACTTTCC, found in the enhancer elements of several viral promoters, including human immunodeficiency virus (HIV), and to related sequences found in the enhancer elements of a number of cellular promoters. This protein binds to this sequence motif, suggesting a role in the transcriptional regulation of both viral and cellular genes. [provided by RefSeq, Oct 2011]
GeneCards Summary for HIVEP1 Gene
HIVEP1 (Human Immunodeficiency Virus Type I Enhancer Binding Protein 1) is a Protein Coding gene. Diseases associated with HIVEP1 include Esophageal Varix. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is HIVEP3.
UniProtKB/Swiss-Prot for HIVEP1 Gene
-
This protein specifically binds to the DNA sequence 5-GGGACTTTCC-3 which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS (IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HIVEP1 Gene
Genomics for HIVEP1 Gene
Regulatory Elements for HIVEP1 Gene
Enhancers for HIVEP1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HIVEP1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for HIVEP1 Gene
- Chromosome:
- 6
- Start:
- 12,007,653 bp from pter
- End:
- 12,164,999 bp from pter
- Size:
- 157,347 bases
- Orientation:
- Plus strand
Genomic View for HIVEP1 Gene
Genes around HIVEP1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p24.1 by Ensembl
- 6p24.1 by Entrez Gene
- 6p24.1 by HGNC
HIVEP1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HIVEP1 Gene
Proteins for HIVEP1 Gene
-
Protein details for HIVEP1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P15822-ZEP1_HUMAN
- Recommended name:
- Zinc finger protein 40
- Protein Accession:
- P15822
- B2RTU3
- Q14122
- Q5MPB1
- Q5VW60
Protein attributes for HIVEP1 Gene
- Size:
- 2718 amino acids
- Molecular mass:
- 296865 Da
- Quaternary structure:
-
- Interacts with UTP4.
- SequenceCaution:
-
- Sequence=CAA35798.1; Type=Frameshift; Positions=Several; Evidence={ECO:0000305}; Sequence=CAH73909.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAH73982.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI14768.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI21070.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for HIVEP1 Gene
Post-translational modifications for HIVEP1 Gene
Other Protein References for HIVEP1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for HIVEP1
-
Abcam antibodies for HIVEP1
- Invitrogen Antibodies for HIVEP1
- antibodies-online Antibodies for HIVEP1: See all 6
- Search GeneTex for Antibodies for HIVEP1
-
Santa Cruz Biotechnology (SCBT) Antibodies for HIVEP1
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HIVEP1
- Origene Custom Protein Services for HIVEP1
- Novus Biologicals proteins for HIVEP1
- Search GeneTex for Proteins for HIVEP1
Assay Products
No data available for DME Specific Peptides for HIVEP1 Gene
Domains & Families for HIVEP1 Gene
Gene Families for HIVEP1 Gene
Protein Domains for HIVEP1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for HIVEP1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P15822UniProtKB/Swiss-Prot:
ZEP1_HUMAN :- Contains two sets of 2 zinc-fingers, which are widely separated and recognize the same DNA sequence. There is a fifth zinc-finger in-between.
- Domain:
-
- Contains two sets of 2 zinc-fingers, which are widely separated and recognize the same DNA sequence. There is a fifth zinc-finger in-between.
Function for HIVEP1 Gene
Molecular function for HIVEP1 Gene
- GENATLAS Biochemistry:
- human immunodeficiency virus type I enhancer binding protein 1,MHC binding protein 1,positive regulatory domain II binding (HIV - EP1/MBP1/PRDII - BF1)
- UniProtKB/Swiss-Prot Function:
- This protein specifically binds to the DNA sequence 5-GGGACTTTCC-3 which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS (IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.
- UniProtKB/Swiss-Prot Induction:
- By mitogens and phorbol ester.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | IEA | -- |
| GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding | IEA,IBA | -- |
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003677 | DNA binding | TAS | 2106471 |
| GO:0005515 | protein binding | IPI | 16713569 |
Phenotypes for HIVEP1 Gene
- MGI mutant phenotypes for HIVEP1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for HIVEP1:
Animal Models for HIVEP1 Gene
- MGI Knock Outs for HIVEP1:
-
- Hivep1 tm1Sis
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for HIVEP1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HIVEP1 gene
- Search ViGene Biosciences for HIVEP1
CRISPR Products
-
OriGene CRISPR knockouts for HIVEP1
-
Santa Cruz Biotechnology (SCBT) CRISPR for HIVEP1
- GenScript: Design CRISPR guide RNA sequences for HIVEP1
miRNA for HIVEP1 Gene
- miRTarBase miRNAs that target HIVEP1
-
- hsa-mir-221-3p (MIRT024164)
- hsa-mir-98-5p (MIRT027541)
- hsa-mir-32-5p (MIRT028301)
- hsa-mir-23a-3p (MIRT050384)
- hsa-mir-363-3p (MIRT053566)
- hsa-mir-25-3p (MIRT167703)
- hsa-mir-92a-3p (MIRT167704)
- hsa-mir-367-3p (MIRT167705)
- hsa-mir-433-3p (MIRT167706)
- hsa-mir-92b-3p (MIRT167707)
- hsa-mir-1206 (MIRT167709)
- hsa-mir-7154-5p (MIRT167718)
- hsa-mir-595 (MIRT217683)
- hsa-mir-410-3p (MIRT315729)
- hsa-mir-3613-3p (MIRT536876)
- hsa-mir-190a-3p (MIRT536877)
- hsa-mir-3163 (MIRT536878)
- hsa-mir-548e-5p (MIRT536879)
miRNA Products
- Search ViGene Biosciences for HIVEP1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HIVEP1
- Browse OriGene Inhibitory RNA Products For HIVEP1
-
ViGene Biosciences ready-to-package AAV shRNAs for HIVEP1 gene
Cell Line Products
-
Horizon Cell Lines for HIVEP1
-
ViGene Biosciences adenoviral particle packaged cDNA for HIVEP1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HIVEP1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HIVEP1 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HIVEP1 Gene
Localization for HIVEP1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HIVEP1 Gene
- Isoform 1: Nucleus.
- Isoform 2: Cytoplasm. Nucleus.
- Isoform 3: Cytoplasm. Nucleus.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| nucleus | 5 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA,TAS | 19732766 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005739 | mitochondrion | IDA | -- |
| GO:0016604 | nuclear body | IDA | -- |
Pathways & Interactions for HIVEP1 Gene
No Data Available
Interacting Proteins for HIVEP1 Gene
Selected Interacting proteins:
P15822-ZEP1_HUMAN
ENSP00000368698
for HIVEP1 Gene via
MINT
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | IEA | -- |
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006366 | transcription from RNA polymerase II promoter | IBA | -- |
| GO:0007165 | signal transduction | IBA | -- |
No data available for Pathways by source and SIGNOR curated interactions for HIVEP1 Gene
Transcripts for HIVEP1 Gene
mRNA/cDNA for HIVEP1 Gene
- (15) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (91) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HIVEP1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for HIVEP1
-
Santa Cruz Biotechnology (SCBT) CRISPR for HIVEP1
- GenScript: Design CRISPR guide RNA sequences for HIVEP1
miRNA Products
- Search ViGene Biosciences for HIVEP1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HIVEP1
- Browse OriGene Inhibitory RNA Products For HIVEP1
-
ViGene Biosciences ready-to-package AAV shRNAs for HIVEP1 gene
Flow Cytometry Products
Expression for HIVEP1 Gene
This gene is overexpressed in Heart (57.2) and Adipocyte (11.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for HIVEP1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of HIVEP1 Gene:
HIVEP1SOURCE GeneReport for Unigene cluster for HIVEP1 Gene:
Hs.567284Evidence on tissue expression from TISSUES for HIVEP1 Gene
- Liver(4.3)
Primer Products
-
OriGene qPCR primer pairs for HIVEP1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HIVEP1 Gene
Orthologs for HIVEP1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HIVEP1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | HIVEP1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Hivep1 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Hivep1 34 |
|
||
| cow (Bos Taurus) |
Mammalia | HIVEP1 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | HIVEP1 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | HIVEP1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | HIVEP1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | HIVEP1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | hivep1 34 |
|
||
| Str.7401 34 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | hivep1 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | shn 36 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | sma-9 35 |
|
OneToMany |
- Species where no ortholog for HIVEP1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for HIVEP1 Gene
(10) SIMAP similar genes for HIVEP1 Gene using alignment to 9 proteins:
Variants for HIVEP1 Gene
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs776300630 | Pathogenic | 12,123,884(+) | GAAAT(C/G/T)AGGCG | nc-transcript-variant, reference, missense | |
| rs1000001951 | -- | 12,033,868(+) | TCTTA(A/C)ACTAG | intron-variant | |
| rs1000013027 | -- | 12,181,343(+) | CAACA(-/GAGT)GAGAC | intron-variant | |
| rs1000028970 | -- | 12,140,410(+) | ATGGG(C/G)AGAAA | intron-variant | |
| rs1000068408 | -- | 12,190,288(+) | TCAAA(A/G)TTGAA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv22880 | CNV | gain+loss | 19812545 |
| esv2656995 | CNV | deletion | 23128226 |
| esv2662717 | CNV | deletion | 23128226 |
| esv2670070 | CNV | deletion | 23128226 |
| esv2677354 | CNV | deletion | 23128226 |
| esv3303878 | CNV | mobile element insertion | 20981092 |
| esv3309155 | CNV | mobile element insertion | 20981092 |
| esv3374004 | CNV | insertion | 20981092 |
| esv3398493 | CNV | insertion | 20981092 |
| esv3430431 | CNV | insertion | 20981092 |
| esv3570771 | CNV | loss | 25503493 |
| esv3608104 | CNV | loss | 21293372 |
| esv3608105 | CNV | loss | 21293372 |
| nsv1074378 | CNV | deletion | 25765185 |
| nsv1074910 | CNV | deletion | 25765185 |
| nsv1119071 | CNV | deletion | 24896259 |
| nsv509116 | CNV | insertion | 20534489 |
| nsv830586 | CNV | gain | 17160897 |
| nsv950770 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
14.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
10.52;
91.13% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HIVEP1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HIVEP1 Gene
Disorders for HIVEP1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| esophageal varix |
|
|
Search HIVEP1 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for HIVEP1
No data available for UniProtKB/Swiss-Prot and Genatlas for HIVEP1 Gene
Publications for HIVEP1 Gene
- Cirhin up-regulates a canonical NF-kappaB element through strong interaction with Cirip/HIVEP1. (PMID: 19732766) Yu B. … Richter A. (Exp. Cell Res. 2009) 3 4 22 64
- Transcription factor PRDII-BF1 activates human immunodeficiency virus type 1 gene expression. (PMID: 8289330) Seeler J.S. … Gaynor R.B. (J. Virol. 1994) 3 4 22 64
- High-resolution solution structure of the double Cys2His2 zinc finger from the human enhancer binding protein MBP-1. (PMID: 1567844) Omichinski J.G. … Gronenborn A.M. (Biochemistry 1992) 3 4 22 64
- Regulation of human immunodeficiency virus enhancer function by PRDII-BF1 and c-rel gene products. (PMID: 1727488) Muchardt C. … Gaynor R.B. (J. Virol. 1992) 3 4 22 64
- Localization of the zinc finger DNA-binding protein HIV-EP1/MBP-1/PRDII-BF1 to human chromosome 6p22.3-p24. (PMID: 2037300) Gaynor R.B. … Lusis A.J. (Genomics 1991) 2 3 22 64
Products for HIVEP1 Gene
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- Novus Biologicals Antibodies for HIVEP1
- Novus Biologicals proteins for HIVEP1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for HIVEP1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for HIVEP1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for HIVEP1 gene
- Search ViGene Biosciences for HIVEP1
- Santa Cruz Biotechnology (SCBT) Antibodies for HIVEP1
- Search Santa Cruz Biotechnology (SCBT) for HIVEP1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HIVEP1
- Horizon Cell Lines for HIVEP1
- Cyagen custom Knockout/knockin (KOKI) mouse models for HIVEP1
- VectorBuilder custom plasmid, inducible vectors for HIVEP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HIVEP1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HIVEP1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer