Aliases for HIST3H2BB Gene
Aliases for HIST3H2BB Gene
External Ids for HIST3H2BB Gene
- HGNC: 20514
- Entrez Gene: 128312
- Ensembl: ENSG00000196890
- OMIM: 615046
- UniProtKB: Q8N257
Previous GeneCards Identifiers for HIST3H2BB Gene
- GC01P224384
- GC01P225031
- GC01P225620
- GC01P224952
- GC01P226712
- GC01P228645
- GC01P199161
Summaries for HIST3H2BB Gene
-
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]
GeneCards Summary for HIST3H2BB Gene
HIST3H2BB (Histone Cluster 3 H2B Family Member B) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BN.
UniProtKB/Swiss-Prot for HIST3H2BB Gene
-
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HIST3H2BB Gene
Genomics for HIST3H2BB Gene
Regulatory Elements for HIST3H2BB Gene
Enhancers for HIST3H2BB Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HIST3H2BB on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for HIST3H2BB Gene
- Chromosome:
- 1
- Start:
- 228,458,107 bp from pter
- End:
- 228,460,470 bp from pter
- Size:
- 2,364 bases
- Orientation:
- Plus strand
Genomic View for HIST3H2BB Gene
Genes around HIST3H2BB on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q42.13 by Ensembl
- 1q42.13 by Entrez Gene
- 1q42.13 by HGNC
HIST3H2BB Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HIST3H2BB Gene
Proteins for HIST3H2BB Gene
-
Protein details for HIST3H2BB Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N257-H2B3B_HUMAN
- Recommended name:
- Histone H2B type 3-B
- Protein Accession:
- Q8N257
- A4FU05
- Q3ZCP6
- Q5TA30
Protein attributes for HIST3H2BB Gene
- Size:
- 126 amino acids
- Molecular mass:
- 13908 Da
- Quaternary structure:
-
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Protein Expression for HIST3H2BB Gene
Post-translational modifications for HIST3H2BB Gene
- Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells, including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. It is also associated with post-meiotically activated genes on autosomes.
- GlcNAcylation at Ser-113 promotes monoubiquitination of Lys-121. It fluctuates in response to extracellular glucose, and associates with transcribed genes (By similarity).
- Monoubiquitination at Lys-35 (H2BK34Ub) by the MSL1/MSL2 dimer is required for histone H3 Lys-4 (H3K4me) and Lys-79 (H3K79me) methylation and transcription activation at specific gene loci, such as HOXA9 and MEIS1 loci. Similarly, monoubiquitination at Lys-121 (H2BK120Ub) by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 Lys-4 and Lys-79 methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II. H2BK120Ub also acts as a regulator of mRNA splicing: deubiquitination by USP49 is required for efficient cotranscriptional splicing of a large set of exons.
- Phosphorylation at Ser-37 (H2BS36ph) by AMPK in response to stress promotes transcription (By similarity). Phosphorylated on Ser-15 (H2BS14ph) by STK4/MST1 during apoptosis; which facilitates apoptotic chromatin condensation. Also phosphorylated on Ser-15 in response to DNA double strand breaks (DSBs), and in correlation with somatic hypermutation and immunoglobulin class-switch recombination.
- Ubiquitination at isoforms=121
- Glycosylation at posLast=113113
- Modification sites at PhosphoSitePlus
Other Protein References for HIST3H2BB Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore top HIST3H2BB Antibody
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for HIST3H2BB
- Novus Biologicals Antibodies for HIST3H2BB
- Invitrogen Antibodies for HIST3H2BB
- Search GeneTex for Antibodies for HIST3H2BB
Protein Products
- EMD Millipore Purified and/or Recombinant HIST3H2BB Protein
-
OriGene Purified Proteins for HIST3H2BB
- Search Origene for MassSpec and Protein Over-expression Lysates for HIST3H2BB
- Origene Custom Protein Services for HIST3H2BB
- antibodies-online Proteins for HIST3H2BB: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Proteins for HIST3H2BB
Assay Products
No data available for DME Specific Peptides for HIST3H2BB Gene
Domains & Families for HIST3H2BB Gene
Gene Families for HIST3H2BB Gene
- HGNC:
Protein Domains for HIST3H2BB Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for HIST3H2BB Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8N257- Family:
-
- Belongs to the histone H2B family.
Function for HIST3H2BB Gene
Molecular function for HIST3H2BB Gene
- UniProtKB/Swiss-Prot Function:
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
| GO:0003677 | DNA binding | IBA | -- |
| GO:0046982 | protein heterodimerization activity | IEA | -- |
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for HIST3H2BB gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HIST3H2BB gene
- Search ViGene Biosciences for HIST3H2BB
CRISPR Products
-
OriGene CRISPR knockouts for HIST3H2BB
-
Santa Cruz Biotechnology (SCBT) CRISPR for HIST3H2BB
- GenScript: Design CRISPR guide RNA sequences for HIST3H2BB
miRNA for HIST3H2BB Gene
- miRTarBase miRNAs that target HIST3H2BB
-
- hsa-mir-34a-5p (MIRT025276)
- hsa-mir-5693 (MIRT511560)
- hsa-mir-6839-3p (MIRT511561)
- hsa-mir-4507 (MIRT511562)
- hsa-mir-3940-5p (MIRT511563)
- hsa-mir-8057 (MIRT511564)
- hsa-mir-23b-5p (MIRT511565)
- hsa-mir-23a-5p (MIRT511566)
- hsa-mir-6822-3p (MIRT511567)
- hsa-mir-4766-5p (MIRT511568)
- hsa-mir-146a-3p (MIRT511569)
- hsa-mir-1276 (MIRT511570)
- hsa-mir-760 (MIRT511571)
- hsa-mir-6759-5p (MIRT523188)
- hsa-mir-6793-5p (MIRT523189)
- hsa-mir-6748-5p (MIRT523190)
- hsa-mir-4483 (MIRT523191)
- hsa-mir-1293 (MIRT523192)
- hsa-mir-6766-5p (MIRT523193)
- hsa-mir-6756-5p (MIRT523194)
- hsa-mir-6745 (MIRT523195)
- hsa-mir-363-5p (MIRT523196)
- hsa-mir-24-3p (MIRT610567)
- hsa-mir-4330 (MIRT610568)
- hsa-mir-10b-3p (MIRT610569)
- hsa-mir-8485 (MIRT610570)
- hsa-mir-4769-5p (MIRT713702)
- hsa-mir-615-5p (MIRT713703)
- hsa-mir-5192 (MIRT713704)
- hsa-mir-4644 (MIRT713705)
- hsa-mir-4306 (MIRT713706)
- hsa-mir-185-5p (MIRT713707)
- hsa-mir-8082 (MIRT713708)
- hsa-mir-4534 (MIRT713709)
- hsa-mir-6732-5p (MIRT713710)
miRNA Products
- Search ViGene Biosciences for HIST3H2BB
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HIST3H2BB
- Browse OriGene Inhibitory RNA Products For HIST3H2BB
-
ViGene Biosciences ready-to-package AAV shRNAs for HIST3H2BB gene
Clone Products
-
OriGene ORF clones in human for HIST3H2BB
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for HIST3H2BB
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for HIST3H2BB
-
ViGene Biosciences adenoviral particle packaged cDNA for HIST3H2BB gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HIST3H2BB gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HIST3H2BB gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HIST3H2BB Gene
Localization for HIST3H2BB Gene
Subcellular locations from UniProtKB/Swiss-Prot for HIST3H2BB Gene
- Nucleus. Chromosome.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 4 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000786 | nucleosome | IEA | -- |
| GO:0005634 | nucleus | IDA,IEA | 16319397 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005694 | chromosome | IEA | -- |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for HIST3H2BB Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 |
.88
|
.34
|
| 2 | DNA Double-Strand Break Repair |
.53
|
|
| 3 | Cellular Senescence | ||
| 4 | Chromosome Maintenance | ||
| 5 | Cell Cycle, Mitotic |
.83
|
.60
|
Pathways by source for HIST3H2BB Gene
66 Reactome pathways for HIST3H2BB Gene
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Activation of HOX genes during differentiation
- Amyloid fiber formation
- B-WICH complex positively regulates rRNA expression
3 KEGG pathways for HIST3H2BB Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006334 | nucleosome assembly | IBA | -- |
No data available for SIGNOR curated interactions for HIST3H2BB Gene
Transcripts for HIST3H2BB Gene
mRNA/cDNA for HIST3H2BB Gene
- (1) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (6) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HIST3H2BB Gene
CRISPR Products
-
OriGene CRISPR knockouts for HIST3H2BB
-
Santa Cruz Biotechnology (SCBT) CRISPR for HIST3H2BB
- GenScript: Design CRISPR guide RNA sequences for HIST3H2BB
miRNA Products
- Search ViGene Biosciences for HIST3H2BB
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HIST3H2BB
- Browse OriGene Inhibitory RNA Products For HIST3H2BB
-
ViGene Biosciences ready-to-package AAV shRNAs for HIST3H2BB gene
Clone Products
-
OriGene ORF clones in human for HIST3H2BB
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for HIST3H2BB
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for HIST3H2BB Gene
mRNA differential expression in normal tissues according to GTEx for HIST3H2BB Gene
This gene is overexpressed in Brain - Cerebellar Hemisphere (x6.9), Cervix - Ectocervix (x6.0), Brain - Spinal cord (cervical c-1) (x4.2), and Brain - Cerebellum (x4.1).
This gene is overexpressed in CD8 Tcells (16.8), Pancreas (14.6), NK cells (8.8), Testis (8.1), Ovary (7.9), and Fetal gut (6.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for HIST3H2BB Gene
NURSA nuclear receptor signaling pathways regulating expression of HIST3H2BB Gene:
HIST3H2BBSOURCE GeneReport for Unigene cluster for HIST3H2BB Gene:
Hs.376691Primer Products
-
OriGene qPCR primer pairs for HIST3H2BB
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HIST3H2BB Gene
Orthologs for HIST3H2BB Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HIST3H2BB 35 |
|
OneToOne | |
| LOC469701 34 |
|
||||
| dog (Canis familiaris) |
Mammalia | -- 35 |
|
OneToMany | |
| LOC482202 34 |
|
||||
| mouse (Mus musculus) |
Mammalia | Hist3h2ba 35 |
|
OneToOne | |
| Hist3h2bb-ps 34 16 |
|
||||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
ManyToMany | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
ManyToMany | |
| rat (Rattus norvegicus) |
Mammalia | Hist3h2bb 34 |
|
||
| cow (Bos Taurus) |
Mammalia | HIST3H2BB 34 35 |
|
||
| chicken (Gallus gallus) |
Aves | H2B-V 35 |
|
ManyToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
ManyToMany | |
| zebrafish (Danio rerio) |
Actinopterygii | zgc:194989 35 |
|
ManyToMany | |
| wu:fe11b02 35 35 35 35 35 35 35 35 |
|
ManyToMany | |||
| ano9a 35 35 |
|
ManyToMany | |||
| zgc:171759 35 35 35 35 35 35 35 35 35 35 |
|
ManyToMany | |||
| si:dkey-261m9.19 35 |
|
ManyToMany | |||
| si:dkey-261m9.6 35 |
|
ManyToMany | |||
| zgc:112234 35 35 35 35 35 |
|
ManyToMany | |||
| zgc:173587 35 |
|
ManyToMany | |||
| CABZ01086354.1 35 |
|
ManyToMany |
- Species where no ortholog for HIST3H2BB was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for HIST3H2BB Gene
Paralogs for HIST3H2BB Gene
(23) SIMAP similar genes for HIST3H2BB Gene using alignment to 1 proteins:
Pseudogenes.org Pseudogenes for HIST3H2BB Gene
Variants for HIST3H2BB Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000238442 | -- | 228,458,768(+) | AGTAA(C/T)GTTGG | downstream-variant-500B, upstream-variant-2KB | |
| rs1001050817 | -- | 228,458,095(+) | CCGAG(C/G)GCCGC | upstream-variant-2KB | |
| rs1002053230 | -- | 228,457,188(+) | TTCCC(-/TGT)TGTTA | downstream-variant-500B, upstream-variant-2KB | |
| rs1002084351 | -- | 228,457,042(+) | TTGAT(G/T)ACCAC | downstream-variant-500B, upstream-variant-2KB | |
| rs1003133451 | -- | 228,457,383(+) | AAGAG(A/C)CTTTA | upstream-variant-2KB, utr-variant-3-prime |
Residual Variation Intolerance Score:
23.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.32;
7.12% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HIST3H2BB Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HIST3H2BB
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HIST3H2BB Gene
Disorders for HIST3H2BB Gene
Relevant External Links for HIST3H2BB
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- HIST3H2BB
No disorders were found for HIST3H2BB Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HIST3H2BB Gene
Publications for HIST3H2BB Gene
- The human and mouse replication-dependent histone genes. (PMID: 12408966) Marzluff W.F. … Maltais L.J. (Genomics 2002) 2 3 4 64
- Characterization of histones H2A and H2B variants and their post- translational modifications by mass spectrometry. (PMID: 16319397) Bonenfant D. … van Oostrum J. (Mol. Cell. Proteomics 2006) 3 4 64
- Quantitative proteomic analysis of post-translational modifications of human histones. (PMID: 16627869) Beck H.C. … Jensen O.N. (Mol. Cell. Proteomics 2006) 3 4 64
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
- Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. (PMID: 16713563) Pavri R. … Reinberg D. (Cell 2006) 3 4 64
Products for HIST3H2BB Gene
- Browse Small Molecules at EMD Millipore
- EMD Millipore top HIST3H2BB Antibody
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for HIST3H2BB
- EMD Millipore Purified and/or Recombinant HIST3H2BB Protein
- Browse Kits and Assays available from EMD Millipore
- EMD Millipore genomic analysis products
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for HIST3H2BB
- Search Origene for MassSpec and Protein Over-expression Lysates for HIST3H2BB
- Origene Custom Protein Services for HIST3H2BB
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HIST3H2BB
- Browse OriGene Inhibitory RNA Products For HIST3H2BB
- OriGene qPCR primer pairs for HIST3H2BB
- OriGene CRISPR knockouts for HIST3H2BB
- OriGene ORF clones in human for HIST3H2BB
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HIST3H2BB
- GenScript: Next-day shipping cDNA ORF clone for HIST3H2BB in any vector
- GenScript Custom Purified and Recombinant Proteins Services for HIST3H2BB
- GenScript Custom Assay Services for HIST3H2BB
- GenScript Custom overexpressing Cell Line Services for HIST3H2BB
- GenScript: Design CRISPR guide RNA sequences for HIST3H2BB
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for HIST3H2BB
- Sino Biological Human cDNA Clone for HIST3H2BB
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for HIST3H2BB
- Novus Biologicals proteins and lysates for HIST3H2BB
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Invitrogen Antibodies for HIST3H2BB
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ViGene Biosciences adenoviral particle packaged cDNA for HIST3H2BB gene
- ViGene Biosciences lentiviral particle packaged cDNA for HIST3H2BB gene
- ViGene Biosciences ready-to-package AAV shRNAs for HIST3H2BB gene
- Search ViGene Biosciences for HIST3H2BB
- Search Santa Cruz Biotechnology (SCBT) for HIST3H2BB Antibodies
- Search Santa Cruz Biotechnology (SCBT) for HIST3H2BB siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HIST3H2BB
- Horizon Cell Lines for HIST3H2BB
- Cyagen custom Knockout/knockin (KOKI) mouse models for HIST3H2BB
- VectorBuilder custom plasmid, inducible vectors for HIST3H2BB
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HIST3H2BB
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HIST3H2BB Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer