HIST2H4B Gene
protein-coding GIFtS: 50
GCID: GC01M149830
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|
histone cluster 2, H4b(Previous names: histone 2, H4b )
| |
Aliases
for HIST2H4B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Histone Cluster 2, H4b1 2 | | H4/O3 | | H4/O3 | | H4F23 | | Histone 2, H4b1 2 | | H4FA3 | | Histone H42 | | H4FB3 | | H4/A3 | | H4FC3 | | H4/B3 | | H4FD3 | | H4/C3 | | H4FE3 | | H4/D3 | | H4FG3 | | H4/E3 | | H4FH3 | | H4/G3 | | H4FI3 | | H4/H3 | | H4FJ3 | | H4/I3 | | H4FK3 | | H4/J3 | | H4FM3 | | H4/K3 | | H4FN3 | | H4/M3 | | H4FO3 | | H4/N3 | | HIST2H43 |
Export aliases for HIST2H4B gene to outside databasesPrevious GC identifers: GC01U901311 GC01M148097 GC01M148092 GC01M148100 GC01M149829 GC01P121186 |
Summaries
for HIST2H4B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for HIST2H4B:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber ineukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed ofpairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through theinteraction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails;instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. Thisgene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: H4_HUMAN, P62805Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodeling
|
Genomic Views
for HIST2H4B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HIST2H4B gene promoter:
TBP AP-2alpha isoform 3 Pax-2 Pax-2a Nkx2-5 AP-2alpha isoform 2 Egr-4 AP-2alpha isoform 4 AP-2alpha AP-2alphaA
Other transcription factors
Search SABiosciences Chromatin IP Primers for HIST2H4B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIST2H4B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21 Ensembl cytogenetic band: 1q21.2 HGNC cytogenetic band: 1q21.2HIST2H4B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M149830: view genomic region
(about GC identifiers)
Start:
|
149,825,607 bp from pter |
End:
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149,832,725 bp from pter |
Size:
|
7,119 bases |
Orientation:
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minus strand |
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Proteins
for HIST2H4B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: H4_HUMAN, P62805 (See
protein sequence)Recommended Name: Histone H4 Size: 103 amino acids; 11367 Da
Subunit: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in oneH3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA
Subcellular location: Nucleus. Chromosome
Sequence caution: Sequence=AAI28106.1; Type=Frameshift; Positions=3;
6/46 PDB 3D structures from  and Proteopedia  for HIST2H4B (see all 46):2BQZ (3D)
2CV5 (3D)
2LVM (3D)
2RNY (3D)
2RS9 (3D)
3A6N (3D)
Secondary accessions: A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7Explore the universe of human proteins at neXtProt for HIST2H4B: NX_P62805
Post-translational modifications:
Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of thegenome but not in heterochromatin1
Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation1
Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylationat Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4(H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage1
Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed bySET8. Trimethylation is performed by SUV420H1 and SUV420H2 and induces gene silencing1
Phosphorylated by PAK2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histonechaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H41
Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interactionbetween histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histoneH4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it mayfunction as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21methylation (H4K20me)1
Sumoylated, which is associated with transcriptional repression1
Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells,including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks activepromoters and enhancers and confers resistance to transcriptional repressors. It is also associated withpost-meiotically activated genes on autosomes1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P62805
HIST2H4B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001029249.1
ENSEMBL proteins: ENSP00000376664 ENSP00000358153 ENSP00000376663 Reactome Protein details: P62805
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
HIST2H4B for ontologies About GeneDecksing
HIST2H4B Antibody Products:
Assay Products for HIST2H4B: |
Protein
Domains /
Families
for HIST2H4B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HIST2H4B for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P62805ProtoNet protein and cluster: P62805 UniProtKB/Swiss-Prot: H4_HUMAN, P62805Similarity: Belongs to the histone H4 family |
Function
for HIST2H4B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: H4_HUMAN, P62805Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodeling
Clone
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Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
HIST2H4B for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for HIST2H4B:
|
Pathways & Interactions
for HIST2H4B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signal transduction Activin A signaling regulation | | | 2 | Transcription_Sin3 and NuRD in transcription regulation | | | 3 | Development_Notch Signaling Pathway | | | 4 | Development NOTCH1-mediated pathway for NF-KB activity modulation | | | 5 | Type II interferon signaling (IFNG) | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5 EMD Millipore Pathways for HIST2H4B
4  GeneGo (Thomson Reuters) Pathways for HIST2H4B
2  BioSystems Pathways for HIST2H4B
5/17 
Reactome Pathways for HIST2H4B (see all 17)
1 
Kegg Pathway (Kegg details for HIST2H4B):
HIST2H4B for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HIST2H4B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/605 Interacting proteins for HIST2H4B (P628051, 2, 3 ENSP000003581534) via UniProtKB, MINT, STRING, and/or I2D (see all 605)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
HIST2H4B for ontologies About GeneDecksing
|
Drugs & Compounds
for HIST2H4B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for HIST2H4B
Search CenterWatch for drugs/clinical trials and news about HIST2H4B / H4
|
Transcripts
for HIST2H4B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HIST2H4B gene: NM_001034077.4 Unigene Clusters for HIST2H4B: Histone cluster 2, H4b Hs.55468 [show with all ESTs], Hs.706635 Unigene Representative Sequences: BQ671323, NM_0010340773 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000392933 ENST00000369157(uc001esz.1) ENST00000392932(uc001eta.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HIST2H4B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HIST2H4B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: HIST2H4B (NM_001034077) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HIST2H4B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HIST2H4B |
15 DOTS entries: DT.454682 DT.121432794 DT.97825938 DT.121432862 DT.308787 DT.121432859 DT.92452709 DT.97768687 DT.97791265 DT.100709488 DT.121437909 DT.121437914 DT.121437916 DT.121432831 DT.95282586
GeneLoc Exon Structure
|
Expression
for HIST2H4B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HIST2H4B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATGTGGTGT
About this image
See HIST2H4B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HIST2H4B
SOURCE GeneReport for Unigene clusters: Hs.55468 Hs.706635
SABiosciences Custom PCR Arrays for HIST2H4B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HIST2H4B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat HIST2H4B | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST2H4B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST2H4B |
Orthologs
for HIST2H4B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals and fungi.
Orthologs for HIST2H4B gene from 4/11 species (see all 11) About this table
ENSEMBL Gene Tree for HIST2H4B (if available)
TreeFam Gene Tree for HIST2H4B (if available) |
Paralogs
for HIST2H4B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for HIST2H4B gene
- HIST2H4A1 2 HIST1H4I1 2 HIST1H4K1 2 HIST1H4J1 2 HIST1H4A1 2 HIST1H4L1 2 HIST1H4F1 2 HIST1H4H1 2
- HIST1H4D1 2 HIST1H4E1 2 HIST1H4B1 2 HIST4H41 2 HIST1H4C1 2 HIST1H4G2
3 SIMAP similar genes for HIST2H4B using alignment to 1 protein entry: H4_HUMAN:HIST1H4J HIST1H4H HIST1H4G
HIST2H4B for paralogs About GeneDecksing
|
Genomic Variants
for HIST2H4B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HIST2H4B (149825607 - 149832725 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 9 variations for HIST2H4B
6 CNVs: 3313 2326 48130 4255 2052 8329
3 Inversions: 0391 37081 37080 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for HIST2H4B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HIST2H4B for disorders About GeneDecksing
7  diseases for HIST2H4B: About MalaCardsnon-hodgkin lymphoma systemic lupus erythematosus lupus erythematosus hodgkin's lymphoma
hepatocellular carcinoma carcinoma leukemia
1 disease from the University of Copenhagen DISEASES database for HIST2H4B:Cancer Export disorders for HIST2H4B gene to outside databases
|
Publications
for HIST2H4B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HIST2H4B gene, integrated from 9 sources (see all 65):
(articles sorted by number of sources associating them with HIST2H4B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Functional characterization of a human histone gene cluster duplication. (PubMed id 15527963)1, 2, 3 Braastad C.D....Stein G.S. (2004)
- The human and mouse replication-dependent histone genes. (PubMed id 12408966)1, 2 Marzluff W.F....Maltais L.J. (2002)
- Protein-DNA interactions in vivo upstream of a cell cycle-regulated human H4 histone gene. (PubMed id 3035717)1, 2 Pauli U.... Nick H. (1987)
- The interaction between ubiquitin C-terminal hydrolas e 37 and glucose-regulated protein 78 in hepatocellular carcinoma. (PubMed id 21800051)1 Fang Y....Shen X. (2012)
- A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. (PubMed id 21925322)2 Tan M.... Zhao Y. (2011)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Activity-based chemical proteomics accelerates inhibi tor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (2011)
- Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)1 Emanuele M.J....Elledge S.J. (2011)
|
External Searches for HIST2H4B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HIST2H4B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HIST2H4B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HIST2H4B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for HIST2H4B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for HIST2H4B gene:
Search GeneIP for patents involving HIST2H4B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HIST2H4B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for HIST2H4B | | OriGene shRNA RFP for HIST2H4B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HIST2H4B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HIST2H4B | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HIST2H4B | | OriGene 3'-UTR Clone for HIST2H4B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HIST2H4B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HIST2H4B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HIST2H4B | | OriGene Custom Protein Services for HIST2H4B | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HIST2H4B | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HIST2H4B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIST2H4B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HIST2H4B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST2H4B | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST2H4B |
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 | | | HIST2H4B Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for HIST2H4B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HIST2H4B |
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