HIST2H3PS2 Gene
pseudogene GIFtS: 23
GCID: GC01M149400
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histone cluster 2, H3, pseudogene 2(Previous names: histone 2, H3, pseudogene 2 )
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Aliases
for HIST2H3PS2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
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| Aliases |
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| Histone Cluster 2, H3, Pseudogene 21 2 | | P061 | | Histone 2, H3, Pseudogene 21 |
Export aliases for HIST2H3PS2 gene to outside databasesPrevious GC identifers: GC01M147666 GC01M147671 |
Summaries
for HIST2H3PS2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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Gene Wiki entry for HIST2H3PS2
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Genomic Views
for HIST2H3PS2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for HIST2H3PS2
Other transcription factors
Search SABiosciences Chromatin IP Primers for HIST2H3PS2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIST2H3PS2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21.2 Ensembl cytogenetic band: 1q21.2 HGNC cytogenetic band: 1q21.1HIST2H3PS2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M149400: view genomic region
(about GC identifiers)
Start:
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149,398,877 bp from pter |
End:
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149,400,542 bp from pter |
Size:
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1,666 bases |
Orientation:
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minus strand |
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Proteins
for HIST2H3PS2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB/TrEMBL: Q5TEC6 (See
protein sequence)Recommended Name: Histone cluster 2, H3, pseudogene 2 Size: 136 amino acids; 15430 Da
1 PDB 3D structure from  and Proteopedia  for HIST2H3PS2:4H75 (3D)
HIST2H3PS2 Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000376675
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
HIST2H3PS2 for ontologies About GeneDecksing
HIST2H3PS2 Antibody Products:
Assay Products for HIST2H3PS2: |
Protein
Domains /
Families
for HIST2H3PS2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
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HIST2H3PS2 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q5TEC6ProtoNet protein and cluster: Q5TEC6 |
Function
for HIST2H3PS2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0003677 | DNA binding |
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HIST2H3PS2 for ontologies About GeneDecksing
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Pathways & Interactions
for HIST2H3PS2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HIST2H3PS2
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0006334 | nucleosome assembly |
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HIST2H3PS2 for ontologies About GeneDecksing
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Drugs & Compounds
for HIST2H3PS2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for HIST2H3PS2
Search CenterWatch for drugs/clinical trials and news about HIST2H3PS2 
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Transcripts
for HIST2H3PS2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for HIST2H3PS2 gene: NM_001025303.1 1 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000392948
1 AceView cDNA sequence: AW995597
GeneLoc Exon Structure
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Expression
for HIST2H3PS2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HIST2H3PS2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See HIST2H3PS2 Protein Expression from SPIRE MOPED and PaxDB SABiosciences Custom PCR Arrays for HIST2H3PS2
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HIST2H3PS2
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat HIST2H3PS2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST2H3PS2 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST2H3PS2 |
Orthologs
for HIST2H3PS2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for HIST2H3PS2 (if available)
TreeFam Gene Tree for HIST2H3PS2 (if available) |
Paralogs
for HIST2H3PS2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for HIST2H3PS2 gene
- CENPA2
18 SIMAP similar genes for HIST2H3PS2 using alignment to 1 protein entry: Q5TEC6_HUMAN:H3F3B HIST1H3A HIST1H3B HIST1H3C HIST1H3D HIST1H3E
HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST2H3A
HIST2H3C HIST2H3D HIST3H3 H3F3A H3F3C CENPA
HIST2H3PS2 for paralogs About GeneDecksing
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Genomic Variants
for HIST2H3PS2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for HIST2H3PS2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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 HIST2H3PS2 for disorders About MalaCards
HIST2H3PS2 for disorders About GeneDecksing
2 diseases from the University of Copenhagen DISEASES database for HIST2H3PS2:Leukemia Retinoblastoma Export disorders for HIST2H3PS2 gene to outside databases
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Publications
for HIST2H3PS2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for HIST2H3PS2 gene, integrated from 9 sources (see all 24):
(articles sorted by number of sources associating them with HIST2H3PS2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human histone H3 complement anno 2011. (PubMed id 21782046)1 Ederveen T.H....Logie C. (2011)
- Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification. (PubMed id 17189264)1 Morris S.A.... Strahl B.D. (2007)
- Organismal differences in post-translational modifications in histones H3 and H4. (PubMed id 17194708)1 Garcia B.A.... Hunt D.F. (2007)
- Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. (PubMed id 16916647)1 Kim S.C.... Zhao Y. (2006)
- Expression patterns and post-translational modifications associated with mammalian histone H3 variants. (PubMed id 16267050)1 Hake S.B.... Hunt D.F. (2006)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1 Gregory S.G.... Bentley D.R. (2006)
- Quantitative proteomic analysis of post-translational modifications of human histones. (PubMed id 16627869)1 Beck H.C.... Jensen O.N. (2006)
- Coactivator-associated arginine methyltransferase-1 enhances nuclear factor-kappaB-mediated gene transcription through methylation of histone H3 at arginine 17. (PubMed id 16497732)1 Miao F.... Natarajan R. (2006)
- Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage. (PubMed id 16678110)1 Wang H.... Zhang Y. (2006)
- Phosphorylation of Ser28 in histone H3 mediated by mixed lineage kinase-like mitogen-activated protein triple kinase alpha. (PubMed id 15684425)1 Choi H.S.... Dong Z. (2005)
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External Searches for HIST2H3PS2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing HIST2H3PS2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing HIST2H3PS2 gene
(According to HUGE)
About This Section
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Specialized Databases showing HIST2H3PS2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for HIST2H3PS2 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for HIST2H3PS2 gene:
Search GeneIP for patents involving HIST2H3PS2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for HIST2H3PS2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HIST2H3PS2 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HIST2H3PS2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIST2H3PS2 | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HIST2H3PS2 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST2H3PS2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST2H3PS2 |
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 | | | | |  |  |  | | | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat HIST2H3PS2 |
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