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HIST2H2BB Gene(Pseudogene)

Histone Cluster 2 H2B Family Member B (Pseudogene)

GCID:
GC01M143875
GIFtS:
13
Genes Participants
UDN Logo

Aliases for HIST2H2BB Gene

Aliases for HIST2H2BB Gene

  • Histone Cluster 2 H2B Family Member B (Pseudogene) 2 3 5
  • Histone Cluster 2, H2bb (Pseudogene) 2
  • Histone Cluster 2, H2bb 2
  • Histone 2, H2bb 2

External Ids for HIST2H2BB Gene

Previous GeneCards Identifiers for HIST2H2BB Gene

  • GC01U900005
  • GC01P120712
  • GC01P120715
  • GC01P120905

Summaries for HIST2H2BB Gene

Entrez Gene Summary for HIST2H2BB Gene

  • Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is a histone pseudogene found on chromosome 1. [provided by RefSeq, Oct 2015]

GeneCards Summary for HIST2H2BB Gene

HIST2H2BB (Histone Cluster 2 H2B Family Member B (Pseudogene)) is a Pseudogene.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HIST2H2BB Gene

Genomics for HIST2H2BB Gene

Products:

  1. Regulatory Element

Regulatory Elements for HIST2H2BB Gene

Enhancers for HIST2H2BB Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G143904 0.6 ENCODE 0.7 -0.7 -707 2.5 SCRT1 CTCF ATF2 POLR2A ZNF366 SCRT2 ZBTB33 CUX1 PIR31911 HIST2H2BB
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around HIST2H2BB on UCSC Golden Path with GeneCards custom track

Promoters for HIST2H2BB Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000012691 -151 2800 SCRT1 CTCF ATF2 POLR2A ZNF366 SCRT2 ZBTB33 CUX1

Genomic Location for HIST2H2BB Gene

Chromosome:
1
Start:
143,875,171 bp from pter
End:
143,904,650 bp from pter
Size:
29,480 bases
Orientation:
Minus strand

Genomic View for HIST2H2BB Gene

Genes around HIST2H2BB on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HIST2H2BB Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HIST2H2BB Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for HIST2H2BB Gene

Proteins for HIST2H2BB Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for HIST2H2BB Gene

No Post-translational modifications

No data available for DME Specific Peptides for HIST2H2BB Gene

Domains & Families for HIST2H2BB Gene

Gene Families for HIST2H2BB Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HIST2H2BB: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HIST2H2BB Gene

Function for HIST2H2BB Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HIST2H2BB Gene

Localization for HIST2H2BB Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HIST2H2BB Gene

Pathways & Interactions for HIST2H2BB Gene

SuperPathways for HIST2H2BB Gene

PathCards logo More details on SuperPathways for HIST2H2BB
No Data Available

Interacting Proteins for HIST2H2BB Gene

Gene Ontology (GO) - Biological Process for HIST2H2BB Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HIST2H2BB Gene

Drugs & Compounds for HIST2H2BB Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for HIST2H2BB Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for HIST2H2BB Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for HIST2H2BB Gene

No ASD Table

Relevant External Links for HIST2H2BB Gene

GeneLoc Exon Structure for
HIST2H2BB
ECgene alternative splicing isoforms for
HIST2H2BB

Expression for HIST2H2BB Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HIST2H2BB Gene

mRNA expression in normal human tissues for HIST2H2BB Gene
mRNA expression by GTEx for HIST2H2BB Gene

mRNA differential expression in normal tissues according to GTEx for HIST2H2BB Gene

This gene is overexpressed in Ovary (x6.3), Adrenal Gland (x5.5), and Stomach (x5.2).

NURSA nuclear receptor signaling pathways regulating expression of HIST2H2BB Gene:

HIST2H2BB
genes like me logo Genes that share expression patterns with HIST2H2BB: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HIST2H2BB Gene

Orthologs for HIST2H2BB Gene

Evolution for HIST2H2BB Gene

ENSEMBL:
Gene Tree for HIST2H2BB (if available)
TreeFam:
Gene Tree for HIST2H2BB (if available)

No data available for Orthologs for HIST2H2BB Gene

Paralogs for HIST2H2BB Gene

No data available for Paralogs for HIST2H2BB Gene

Variants for HIST2H2BB Gene

Relevant External Links for HIST2H2BB Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HIST2H2BB

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for HIST2H2BB Gene

Disorders for HIST2H2BB Gene

No disorders were found for HIST2H2BB Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for HIST2H2BB Gene

Publications for HIST2H2BB Gene

  1. The human and mouse replication-dependent histone genes. (PMID: 12408966) Marzluff W.F. … Maltais L.J. (Genomics 2002) 2 3 64
  2. The human histone H3 complement anno 2011. (PMID: 21782046) Ederveen T.H. … Logie C. (Biochim. Biophys. Acta 2011) 3 64
  3. Birth-and-death long-term evolution promotes histone H2B variant diversification in the male germinal cell line. (PMID: 20194426) GonzA!lez-Romero R. … EirA-n-LA^pez J.M. (Mol. Biol. Evol. 2010) 3 64

Products for HIST2H2BB Gene

Sources for HIST2H2BB Gene

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