Free for academic non-profit institutions. Other users need a Commercial license

Aliases for HIST2H2BA Gene

Aliases for HIST2H2BA Gene

  • Histone Cluster 2 H2B Family Member A (Pseudogene) 2 3 5
  • Histone Cluster 2, H2ba (Pseudogene) 2
  • Histone Cluster 2, H2ba 2
  • Histone 2, H2ba 2

External Ids for HIST2H2BA Gene

Previous GeneCards Identifiers for HIST2H2BA Gene

  • GC01U900038
  • GC01M147000
  • GC01P120618
  • GC01P120707
  • GC01P120907
  • GC01P120909
  • GC01P120912
  • GC01P120916

Summaries for HIST2H2BA Gene

Entrez Gene Summary for HIST2H2BA Gene

  • Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is a histone pseudogene found on chromosome 1. [provided by RefSeq, Oct 2015]

GeneCards Summary for HIST2H2BA Gene

HIST2H2BA (Histone Cluster 2 H2B Family Member A (Pseudogene)) is a Pseudogene.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HIST2H2BA Gene

Genomics for HIST2H2BA Gene

Regulatory Elements for HIST2H2BA Gene

Enhancers for HIST2H2BA Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G121518 1 ENCODE 22.5 -402.1 -402067 1.9 FOXA2 ZNF493 ZNF133 DMAP1 ZNF2 ZNF48 GLIS2 KLF7 SP3 YY2 HIST2H2BA ENSG00000227082 GC01M121519 EMBP1
GH01G121366 0.8 dbSUPER 6.7 -251.6 -251615 4.8 BCOR HDAC1 LEF1 TAL1 TCF12 NCOR1 EGR1 TRIM24 SMARCA5 RNF2 HIST2H2BA PIR52368 PIR43395
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around HIST2H2BA on UCSC Golden Path with GeneCards custom track

Promoters for HIST2H2BA Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000012557 -244 3000

Genomic Location for HIST2H2BA Gene

Chromosome:
1
Start:
121,108,210 bp from pter
End:
121,117,257 bp from pter
Size:
9,048 bases
Orientation:
Minus strand

Genomic View for HIST2H2BA Gene

Genes around HIST2H2BA on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HIST2H2BA Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HIST2H2BA Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HIST2H2BA Gene

Proteins for HIST2H2BA Gene

Post-translational modifications for HIST2H2BA Gene

No Post-translational modifications

No data available for DME Specific Peptides for HIST2H2BA Gene

Domains & Families for HIST2H2BA Gene

Gene Families for HIST2H2BA Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HIST2H2BA: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HIST2H2BA Gene

Function for HIST2H2BA Gene

Phenotypes for HIST2H2BA Gene

genes like me logo Genes that share phenotypes with HIST2H2BA: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HIST2H2BA Gene

Localization for HIST2H2BA Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HIST2H2BA Gene

Pathways & Interactions for HIST2H2BA Gene

SuperPathways for HIST2H2BA Gene

No Data Available

Interacting Proteins for HIST2H2BA Gene

Gene Ontology (GO) - Biological Process for HIST2H2BA Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HIST2H2BA Gene

Drugs & Compounds for HIST2H2BA Gene

No Compound Related Data Available

Transcripts for HIST2H2BA Gene

mRNA/cDNA for HIST2H2BA Gene

(3) Additional mRNA sequences :
(9) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HIST2H2BA Gene

Histone cluster 2, H2ba (pseudogene):
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for HIST2H2BA Gene

No ASD Table

Relevant External Links for HIST2H2BA Gene

GeneLoc Exon Structure for
HIST2H2BA
ECgene alternative splicing isoforms for
HIST2H2BA

Expression for HIST2H2BA Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HIST2H2BA Gene

mRNA differential expression in normal tissues according to GTEx for HIST2H2BA Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x5.2), Brain - Cerebellum (x4.7), and Ovary (x4.6).

NURSA nuclear receptor signaling pathways regulating expression of HIST2H2BA Gene:

HIST2H2BA

SOURCE GeneReport for Unigene cluster for HIST2H2BA Gene:

Hs.742189
genes like me logo Genes that share expression patterns with HIST2H2BA: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HIST2H2BA Gene

Orthologs for HIST2H2BA Gene

Evolution for HIST2H2BA Gene

ENSEMBL:
Gene Tree for HIST2H2BA (if available)
TreeFam:
Gene Tree for HIST2H2BA (if available)

No data available for Orthologs for HIST2H2BA Gene

Paralogs for HIST2H2BA Gene

No data available for Paralogs for HIST2H2BA Gene

Variants for HIST2H2BA Gene

Structural Variations from Database of Genomic Variants (DGV) for HIST2H2BA Gene

Variant ID Type Subtype PubMed ID
nsv524681 CNV gain 19592680

Relevant External Links for HIST2H2BA Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HIST2H2BA

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for HIST2H2BA Gene

Disorders for HIST2H2BA Gene

Relevant External Links for HIST2H2BA

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HIST2H2BA

No disorders were found for HIST2H2BA Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HIST2H2BA Gene

Publications for HIST2H2BA Gene

  1. The human and mouse replication-dependent histone genes. (PMID: 12408966) Marzluff W.F. … Maltais L.J. (Genomics 2002) 2 3 64
  2. Birth-and-death long-term evolution promotes histone H2B variant diversification in the male germinal cell line. (PMID: 20194426) GonzA!lez-Romero R. … EirA-n-LA^pez J.M. (Mol. Biol. Evol. 2010) 3 64
  3. NIR is a novel INHAT repressor that modulates the transcriptional activity of p53. (PMID: 16322561) Hublitz P. … Schule R. (Genes Dev. 2005) 3 64
  4. Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus. (PMID: 14992727) Hughes C.M. … Meyerson M. (Mol. Cell 2004) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for HIST2H2BA Gene

Sources for HIST2H2BA Gene

Content
Loading form....