Aliases for HIST2H2BA Gene
Aliases for HIST2H2BA Gene
External Ids for HIST2H2BA Gene
- HGNC: 20560
- Entrez Gene: 337875
- Ensembl: ENSG00000223345
Previous GeneCards Identifiers for HIST2H2BA Gene
- GC01U900038
- GC01M147000
- GC01P120618
- GC01P120707
- GC01P120907
- GC01P120909
- GC01P120912
- GC01P120916
Summaries for HIST2H2BA Gene
-
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is a histone pseudogene found on chromosome 1. [provided by RefSeq, Oct 2015]
GeneCards Summary for HIST2H2BA Gene
HIST2H2BA (Histone Cluster 2 H2B Family Member A (Pseudogene)) is a Pseudogene.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HIST2H2BA Gene
Genomics for HIST2H2BA Gene
Regulatory Elements for HIST2H2BA Gene
Enhancers for HIST2H2BA Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH01G121518 | 1 | ENCODE | 22.5 | -402.1 | -402067 | 1.9 | FOXA2 ZNF493 ZNF133 DMAP1 ZNF2 ZNF48 GLIS2 KLF7 SP3 YY2 | HIST2H2BA ENSG00000227082 GC01M121519 EMBP1 |
| GH01G121367 | 0.8 | dbSUPER | 6.7 | -251.4 | -251397 | 4.3 | BCOR HDAC1 LEF1 TAL1 TCF12 NCOR1 EGR1 TRIM24 SMARCA5 RNF2 | HIST2H2BA PIR52368 PIR43395 |
| GH01G121366 | 0.5 | dbSUPER | 6.7 | -250.0 | -249994 | 1.5 | NR4A1 TEAD2 NR2C1 | HIST2H2BA PIR52368 ENSG00000275129 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HIST2H2BA on UCSC Golden Path with GeneCards custom track
Promoters for HIST2H2BA Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|---|---|---|
| ENSR00000012557 | -244 | 3000 |
Regulatory Element Products
Genomic Location for HIST2H2BA Gene
- Chromosome:
- 1
- Start:
- 121,108,210 bp from pter
- End:
- 121,117,257 bp from pter
- Size:
- 9,048 bases
- Orientation:
- Minus strand
Genomic View for HIST2H2BA Gene
Genes around HIST2H2BA on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p11.2 by Ensembl
- 1p11.2 by Entrez Gene
- 1p11.2 by HGNC
HIST2H2BA Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HIST2H2BA Gene
Proteins for HIST2H2BA Gene
Post-translational modifications for HIST2H2BA Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for HIST2H2BA
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HIST2H2BA
- Origene Custom Protein Services for HIST2H2BA
- Search GeneTex for Proteins for HIST2H2BA
Assay Products
No data available for DME Specific Peptides for HIST2H2BA Gene
Domains & Families for HIST2H2BA Gene
Gene Families for HIST2H2BA Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HIST2H2BA Gene
Function for HIST2H2BA Gene
Phenotypes for HIST2H2BA Gene
- GenomeRNAi human phenotypes for HIST2H2BA:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Search ViGene Biosciences for HIST2H2BA
CRISPR Products
- Browse CRISPR knockouts for HIST2H2BA
miRNA Products
- Search ViGene Biosciences for HIST2H2BA
Inhibitory RNA Products
- Search ViGene Biosciences for HIST2H2BA
Cell Line Products
- Search ViGene Biosciences for HIST2H2BA
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HIST2H2BA Gene
Localization for HIST2H2BA Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HIST2H2BA Gene
Transcripts for HIST2H2BA Gene
mRNA/cDNA for HIST2H2BA Gene
- (3) Additional mRNA sequences :
- (9) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HIST2H2BA Gene
CRISPR Products
- Browse CRISPR knockouts for HIST2H2BA
miRNA Products
- Search ViGene Biosciences for HIST2H2BA
Inhibitory RNA Products
- Search ViGene Biosciences for HIST2H2BA
Flow Cytometry Products
Expression for HIST2H2BA Gene
mRNA differential expression in normal tissues according to GTEx for HIST2H2BA Gene
This gene is overexpressed in Brain - Cerebellar Hemisphere (x5.2), Brain - Cerebellum (x4.7), and Ovary (x4.6).
NURSA nuclear receptor signaling pathways regulating expression of HIST2H2BA Gene:
HIST2H2BASOURCE GeneReport for Unigene cluster for HIST2H2BA Gene:
Hs.742189Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HIST2H2BA Gene
Orthologs for HIST2H2BA Gene
No data available for Orthologs for HIST2H2BA Gene
Paralogs for HIST2H2BA Gene
No data available for Paralogs for HIST2H2BA Gene
Variants for HIST2H2BA Gene
Relevant External Links for HIST2H2BA Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HIST2H2BA
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for HIST2H2BA Gene
Disorders for HIST2H2BA Gene
Relevant External Links for HIST2H2BA
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- HIST2H2BA
No disorders were found for HIST2H2BA Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HIST2H2BA Gene
Publications for HIST2H2BA Gene
- The human and mouse replication-dependent histone genes. (PMID: 12408966) Marzluff W.F. … Maltais L.J. (Genomics 2002) 2 3 64
- Birth-and-death long-term evolution promotes histone H2B variant diversification in the male germinal cell line. (PMID: 20194426) GonzA!lez-Romero R. … EirA-n-LA^pez J.M. (Mol. Biol. Evol. 2010) 3 64
- NIR is a novel INHAT repressor that modulates the transcriptional activity of p53. (PMID: 16322561) Hublitz P. … Schule R. (Genes Dev. 2005) 3 64
- Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus. (PMID: 14992727) Hughes C.M. … Meyerson M. (Mol. Cell 2004) 3 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
Products for HIST2H2BA Gene
- Browse R&D Systems for Antibodies
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- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Custom Antibody Services
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- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HIST2H2BA
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- Novus Biologicals
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- Cyagen custom Knockout/knockin (KOKI) mouse models for HIST2H2BA
- VectorBuilder custom plasmid, inducible vectors for HIST2H2BA
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HIST2H2BA Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
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- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer