Aliases for HIST2H2AA3 Gene
Aliases for HIST2H2AA3 Gene
External Ids for HIST2H2AA3 Gene
- HGNC: 4736
- Entrez Gene: 8337
- Ensembl: ENSG00000203812
- OMIM: 142720
- UniProtKB: Q6FI13
Previous HGNC Symbols for HIST2H2AA3 Gene
- H2AFO
- HIST2H2AA
Previous GeneCards Identifiers for HIST2H2AA3 Gene
- GC01M148080
- GC01M149813
- GC01P121205
Summaries for HIST2H2AA3 Gene
-
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. [provided by RefSeq, Aug 2015]
GeneCards Summary for HIST2H2AA3 Gene
HIST2H2AA3 (Histone Cluster 2 H2A Family Member A3) is a Protein Coding gene. Diseases associated with HIST2H2AA3 include Retinitis Pigmentosa 20. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Meiosis. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST2H2AA4.
UniProtKB/Swiss-Prot for HIST2H2AA3 Gene
-
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HIST2H2AA3 Gene
Genomics for HIST2H2AA3 Gene
Regulatory Elements for HIST2H2AA3 Gene
- Transcription factor binding sites by QIAGEN in the HIST2H2AA3 gene promoter:
Regulatory Element Products
Genomic Location for HIST2H2AA3 Gene
- Chromosome:
- 1
- Start:
- 149,842,188 bp from pter
- End:
- 149,842,751 bp from pter
- Size:
- 564 bases
- Orientation:
- Minus strand
Genomic View for HIST2H2AA3 Gene
- Cytogenetic band:
-
- 1q21.2 by Ensembl
- 1q21.2 by Entrez Gene
- 1q21.2 by HGNC
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HIST2H2AA3 Gene
Proteins for HIST2H2AA3 Gene
-
Protein details for HIST2H2AA3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6FI13-H2A2A_HUMAN
- Recommended name:
- Histone H2A type 2-A
- Protein Accession:
- Q6FI13
- B2R5F0
- P20670
Protein attributes for HIST2H2AA3 Gene
- Size:
- 130 amino acids
- Molecular mass:
- 14095 Da
- Quaternary structure:
-
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Protein Expression for HIST2H2AA3 Gene
Post-translational modifications for HIST2H2AA3 Gene
- Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells, including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. It is also associated with post-meiotically activated genes on autosomes.
- Deiminated on Arg-4 in granulocytes upon calcium entry.
- Glutamine methylation at Gln-105 (H2AQ104me) by FBL is specifically dedicated to polymerase I. It is present at 35S ribosomal DNA locus and impairs binding of the FACT complex (PubMed:24352239).
- Monoubiquitination of Lys-120 (H2AK119Ub) by RING1, TRIM27 and RNF2/RING2 complex gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. It is involved in the initiation of both imprinted and random X inactivation. Ubiquitinated H2A is enriched in inactive X chromosome chromatin. Ubiquitination of H2A functions downstream of methylation of Lys-27 of histone H3 (H3K27me). H2AK119Ub by RNF2/RING2 can also be induced by ultraviolet and may be involved in DNA repair. Monoubiquitination of Lys-120 (H2AK119Ub) by TRIM27 may promote transformation of cells in a number of breast cancers (PubMed:25470042). Following DNA double-strand breaks (DSBs), it is ubiquitinated through Lys-63 linkage of ubiquitin moieties by the E2 ligase UBE2N and the E3 ligases RNF8 and RNF168, leading to the recruitment of repair proteins to sites of DNA damage. Ubiquitination at Lys-14 and Lys-16 (H2AK13Ub and H2AK15Ub, respectively) in response to DNA damage is initiated by RNF168 that mediates monoubiquitination at these 2 sites, and Lys-63-linked ubiquitin are then conjugated to monoubiquitin; RNF8 is able to extend Lys-63-linked ubiquitin chains in vitro. H2AK119Ub and ionizing radiation-induced Lys-63-linked ubiquitination (H2AK13Ub and H2AK15Ub) are distinct events.
- Phosphorylation on Ser-2 (H2AS1ph) is enhanced during mitosis. Phosphorylation on Ser-2 by RPS6KA5/MSK1 directly represses transcription. Acetylation of H3 inhibits Ser-2 phosphorylation by RPS6KA5/MSK1. Phosphorylation at Thr-121 (H2AT120ph) by VPRBP is present in the regulatory region of many tumor suppresor genes and down-regulates their transcription.
- Symmetric dimethylation on Arg-4 by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage.
- Ubiquitination at isoforms=14 and posLast=1616
- Modification sites at PhosphoSitePlus
Other Protein References for HIST2H2AA3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for HIST2H2AA3
- Novus Biologicals Antibodies for HIST2H2AA3
-
Abcam antibodies for HIST2H2AA3
-
Cloud-Clone Corp. Antibodies for HIST2H2AA3
- Invitrogen Antibodies for HIST2H2AA3
- antibodies-online Antibodies for HIST2H2AA3: See all 31
- GeneTex HIST2H2AA3 antibody for HIST2H2AA3
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HIST2H2AA3
- Origene Custom Protein Services for HIST2H2AA3
- Novus Biologicals proteins for HIST2H2AA3
-
Cloud-Clone Corp. Proteins for HIST2H2AA3
- antibodies-online Proteins for HIST2H2AA3: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Proteins for HIST2H2AA3
Assay Products
No data available for DME Specific Peptides for HIST2H2AA3 Gene
Domains & Families for HIST2H2AA3 Gene
Gene Families for HIST2H2AA3 Gene
- HGNC:
Protein Domains for HIST2H2AA3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
Q6FI13- Family:
-
- Belongs to the histone H2A family.
No data available for Suggested Antigen Peptide Sequences for HIST2H2AA3 Gene
Function for HIST2H2AA3 Gene
Molecular function for HIST2H2AA3 Gene
- UniProtKB/Swiss-Prot Function:
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
| GO:0003677 | DNA binding | IBA | -- |
| GO:0046982 | protein heterodimerization activity | IEA | -- |
Phenotypes for HIST2H2AA3 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for HIST2H2AA3 gene
- Search ViGene Biosciences for HIST2H2AA3
CRISPR Products
-
OriGene CRISPR knockouts for HIST2H2AA3
-
Santa Cruz Biotechnology (SCBT) CRISPR for HIST2H2AA3
- GenScript: Design CRISPR guide RNA sequences for HIST2H2AA3
miRNA for HIST2H2AA3 Gene
- miRTarBase miRNAs that target HIST2H2AA3
-
- hsa-mir-34a-5p (MIRT025387)
- hsa-mir-320c (MIRT036169)
- hsa-mir-940 (MIRT036592)
- hsa-mir-744-5p (MIRT037476)
- hsa-mir-671-5p (MIRT039268)
- hsa-mir-615-3p (MIRT039626)
- hsa-mir-18a-3p (MIRT040781)
- hsa-mir-193b-3p (MIRT041606)
- hsa-mir-425-3p (MIRT042417)
- hsa-mir-424-5p (MIRT042440)
- hsa-mir-320a (MIRT044615)
- hsa-mir-149-5p (MIRT045401)
- hsa-mir-100-5p (MIRT048399)
- hsa-mir-92a-3p (MIRT049338)
- hsa-mir-26a-5p (MIRT050188)
- hsa-mir-25-3p (MIRT050242)
- hsa-mir-17-5p (MIRT050850)
- hsa-mir-2277-5p (MIRT052846)
- hsa-mir-210-5p (MIRT246301)
- hsa-mir-513a-5p (MIRT246302)
- hsa-mir-552-3p (MIRT246303)
- hsa-mir-764 (MIRT246304)
- hsa-mir-3127-3p (MIRT246306)
- hsa-mir-4749-3p (MIRT246308)
- hsa-mir-6756-3p (MIRT246309)
- hsa-mir-8055 (MIRT246311)
- hsa-mir-8081 (MIRT246312)
- hsa-mir-760 (MIRT259828)
- hsa-mir-6822-3p (MIRT259829)
- hsa-mir-146a-3p (MIRT259833)
- hsa-mir-1276 (MIRT259834)
- hsa-mir-8057 (MIRT266336)
- hsa-mir-5693 (MIRT511591)
- hsa-mir-27b-3p (MIRT511592)
- hsa-mir-27a-3p (MIRT511593)
- hsa-mir-6748-5p (MIRT511594)
- hsa-mir-4483 (MIRT511595)
- hsa-mir-1293 (MIRT511596)
- hsa-mir-6766-5p (MIRT511597)
- hsa-mir-6756-5p (MIRT511598)
- hsa-mir-6745 (MIRT511599)
- hsa-mir-363-5p (MIRT511600)
- hsa-mir-4766-5p (MIRT511601)
- hsa-mir-7108-3p (MIRT610563)
- hsa-mir-362-3p (MIRT610564)
- hsa-mir-329-3p (MIRT610565)
- hsa-mir-8485 (MIRT610566)
miRNA Products
- Search ViGene Biosciences for HIST2H2AA3
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HIST2H2AA3
- Browse OriGene Inhibitory RNA Products For HIST2H2AA3
- Search ViGene Biosciences for HIST2H2AA3
Clone Products
-
OriGene ORF clones in human for HIST2H2AA3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for HIST2H2AA3
-
ViGene Biosciences adenoviral particle packaged cDNA for HIST2H2AA3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HIST2H2AA3 gene
- Search ViGene Biosciences for HIST2H2AA3
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HIST2H2AA3 Gene
Localization for HIST2H2AA3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HIST2H2AA3 Gene
- Nucleus. Chromosome.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000786 | nucleosome | IEA | -- |
| GO:0000790 | nuclear chromatin | IBA | -- |
| GO:0005634 | nucleus | IDA | 16319397 |
| GO:0005694 | chromosome | IEA | -- |
| GO:0070062 | extracellular exosome | IDA | 19199708 |
Pathways & Interactions for HIST2H2AA3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 |
.88
|
.34
|
| 2 | Cellular Senescence | ||
| 3 | Chromosome Maintenance | ||
| 4 | Cell Cycle, Mitotic |
.83
|
.60
|
| 5 | Chromatin organization | ||
Pathways by source for HIST2H2AA3 Gene
58 Reactome pathways for HIST2H2AA3 Gene
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Activation of HOX genes during differentiation
- Amyloid fiber formation
- B-WICH complex positively regulates rRNA expression
2 KEGG pathways for HIST2H2AA3 Gene
Interacting Proteins for HIST2H2AA3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006342 | chromatin silencing | IBA | -- |
| GO:0008150 | biological_process | ND | -- |
No data available for SIGNOR curated interactions for HIST2H2AA3 Gene
Drugs & Compounds for HIST2H2AA3 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| calcium | Nutra | 0 |
Transcripts for HIST2H2AA3 Gene
mRNA/cDNA for HIST2H2AA3 Gene
- (1) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (135) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HIST2H2AA3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for HIST2H2AA3
-
Santa Cruz Biotechnology (SCBT) CRISPR for HIST2H2AA3
- GenScript: Design CRISPR guide RNA sequences for HIST2H2AA3
miRNA Products
- Search ViGene Biosciences for HIST2H2AA3
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HIST2H2AA3
- Browse OriGene Inhibitory RNA Products For HIST2H2AA3
- Search ViGene Biosciences for HIST2H2AA3
Clone Products
-
OriGene ORF clones in human for HIST2H2AA3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Relevant External Links for HIST2H2AA3 Gene
- GeneLoc Exon Structure for
- HIST2H2AA3
- ECgene alternative splicing isoforms for
- HIST2H2AA3
Expression for HIST2H2AA3 Gene
mRNA differential expression in normal tissues according to GTEx for HIST2H2AA3 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for HIST2H2AA3 Gene
NURSA nuclear receptor signaling pathways regulating expression of HIST2H2AA3 Gene:
HIST2H2AA3SOURCE GeneReport for Unigene cluster for HIST2H2AA3 Gene:
Hs.530461Evidence on tissue expression from TISSUES for HIST2H2AA3 Gene
- Blood(2.7)
- Liver(2.2)
- Spleen(2.1)
Primer Products
-
OriGene qPCR primer pairs and template standards for HIST2H2AA3
-
OriGene qPCR primer pairs for HIST2H2AA3
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HIST2H2AA3 Gene
Orthologs for HIST2H2AA3 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | HIST2H2AC 35 35 |
|
ManyToMany | |
| LOC788724 34 |
|
||||
| dog (Canis familiaris) |
Mammalia | -- 35 |
|
OneToMany | |
| mouse (Mus musculus) |
Mammalia | Hist2h2aa1 35 |
|
OneToMany | |
| Hist2h2aa2 34 |
|
||||
| chimpanzee (Pan troglodytes) |
Mammalia | -- 35 |
|
OneToMany | |
| HIST2H2AA4 34 |
|
||||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
ManyToMany | |
| rat (Rattus norvegicus) |
Mammalia | Hist2h2aa3 34 |
|
||
| chicken (Gallus gallus) |
Aves | H2A-VII 35 |
|
ManyToMany |
- Species where no ortholog for HIST2H2AA3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Evolution for HIST2H2AA3 Gene
- ENSEMBL:
- Gene Tree for HIST2H2AA3 (if available)
- TreeFam:
- Gene Tree for HIST2H2AA3 (if available)
Paralogs for HIST2H2AA3 Gene
Paralogs for HIST2H2AA3 Gene
(25) SIMAP similar genes for HIST2H2AA3 Gene using alignment to 1 proteins:
Variants for HIST2H2AA3 Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1007920943 | -- | 149,844,530(+) | TTTTT(A/G)TTAGG | upstream-variant-2KB | |
| rs1008923766 | -- | 149,843,539(+) | GCTGT(A/T)TTCCC | upstream-variant-2KB | |
| rs1011724730 | -- | 149,844,454(+) | CCCCC(G/T)TTTTT | upstream-variant-2KB | |
| rs1013129127 | -- | 149,843,932(+) | TTGGT(A/G)TTCCT | upstream-variant-2KB | |
| rs1014933455 | -- | 149,843,543(+) | TTTTC(C/T)CACTG | upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1007634 | OTHER | inversion | 20482838 |
| nsv46 | OTHER | inversion | 15895083 |
| nsv469694 | CNV | loss | 16826518 |
| nsv499132 | OTHER | inversion | 21111241 |
| nsv547843 | CNV | loss | 21841781 |
| nsv7182 | OTHER | inversion | 18451855 |
| nsv824564 | CNV | gain | 20364138 |
| nsv831503 | CNV | gain | 17160897 |
| nsv831525 | CNV | gain | 17160897 |
| nsv946379 | CNV | duplication | 23825009 |
| nsv946381 | CNV | duplication | 23825009 |
Relevant External Links for HIST2H2AA3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HIST2H2AA3
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HIST2H2AA3 Gene
Disorders for HIST2H2AA3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| retinitis pigmentosa 20 |
|
|
Relevant External Links for HIST2H2AA3
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- HIST2H2AA3
No data available for UniProtKB/Swiss-Prot and Genatlas for HIST2H2AA3 Gene
Publications for HIST2H2AA3 Gene
- The relative expression of human histone H2A genes is similar in different types of proliferating cells. (PMID: 8179821) Mannironi C. … Bonner W. (DNA Cell Biol. 1994) 2 3 4 64
- RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA Damage signaling. (PMID: 22980979) Mattiroli F. … Sixma T.K. (Cell 2012) 3 4 64
- Precise characterization of human histones in the H2A gene family by top down mass spectrometry. (PMID: 16457589) Boyne M.T. II … Kelleher N.L. (J. Proteome Res. 2006) 3 4 64
- DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A. (PMID: 16702407) Bergink S. … Dantuma N.P. (Genes Dev. 2006) 3 4 64
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
Products for HIST2H2AA3 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for HIST2H2AA3
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HIST2H2AA3
- Origene Custom Protein Services for HIST2H2AA3
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HIST2H2AA3
- Browse OriGene Inhibitory RNA Products For HIST2H2AA3
- OriGene qPCR primer pairs and template standards for HIST2H2AA3
- OriGene qPCR primer pairs for HIST2H2AA3
- OriGene CRISPR knockouts for HIST2H2AA3
- OriGene ORF clones in human for HIST2H2AA3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HIST2H2AA3
- GenScript: Next-day shipping cDNA ORF clone for HIST2H2AA3 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for HIST2H2AA3
- GenScript Custom Assay Services for HIST2H2AA3
- GenScript Custom overexpressing Cell Line Services for HIST2H2AA3
- GenScript: Design CRISPR guide RNA sequences for HIST2H2AA3
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for HIST2H2AA3
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for HIST2H2AA3
- Novus Biologicals proteins for HIST2H2AA3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cloud-Clone Corp. Antibodies for HIST2H2AA3
- Cloud-Clone Corp. Proteins for HIST2H2AA3
- Browse Assay Kits at Cloud-Clone Corp.
- Invitrogen Antibodies for HIST2H2AA3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online Antibodies for HIST2H2AA3: See all 31
- Search antibodies-online for kits
- antibodies-online Proteins for HIST2H2AA3: See all 5
- Search antibodies-online for peptides
- GeneTex HIST2H2AA3 antibody for HIST2H2AA3
- Search GeneTex for Proteins for HIST2H2AA3
- ViGene Biosciences adenoviral particle packaged cDNA for HIST2H2AA3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for HIST2H2AA3 gene
- Search ViGene Biosciences for HIST2H2AA3
- Search Santa Cruz Biotechnology (SCBT) for HIST2H2AA3 Antibodies
- Search Santa Cruz Biotechnology (SCBT) for HIST2H2AA3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HIST2H2AA3
- Horizon Cell Lines for HIST2H2AA3
- Cyagen custom Knockout/knockin (KOKI) mouse models for HIST2H2AA3
- VectorBuilder custom plasmid, inducible vectors for HIST2H2AA3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HIST2H2AA3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HIST2H2AA3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer




