HIST1H4H Gene
protein-coding GIFtS: 53
GCID: GC06M026281
|
|
histone cluster 1, H4h(Previous names: H4 histone family, member H, histone 1, H4h )
(Previous symbol: H4FH)
| |
Aliases
for HIST1H4H gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Histone Cluster 1, H4h1 2 | | H4/N3 | | H4FH1 2 3 5 | | H4/O3 | | H4/H3 | | H4F23 | | H4 Histone Family, Member H1 2 | | H4FA3 | | Histone 1, H4h1 2 | | H4FB3 | | Histone H42 | | H4FC3 | | H4/A3 | | H4FD3 | | H4/B3 | | H4FE3 | | H4/C3 | | H4FG3 | | H4/D3 | | H4FI3 | | H4/E3 | | H4FJ3 | | H4/G3 | | H4FK3 | | H4/H3 | | H4FM3 | | H4/I3 | | H4FN3 | | H4/J3 | | H4FO3 | | H4/K3 | | HIST2H43 | | H4/M3 | | |
Export aliases for HIST1H4H gene to outside databasesPrevious GC identifers: GC06M026339 GC06M026389 GC06M026228 |
Summaries
for HIST1H4H gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for HIST1H4H:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber ineukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around whichapproximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts withlinker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene isintronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but insteadcontain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: H4_HUMAN, P62805Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodeling
Gene Wiki entry for HIST1H4H
|
Genomic Views
for HIST1H4H gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HIST1H4H gene promoter:
SRF SRF (504 AA) HSF1 (long) Nkx2-5 Arnt GATA-1 Max HSF1short SEF-1 (1) c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for HIST1H4H
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIST1H4H |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p22.1 Ensembl cytogenetic band: 6p22.2 HGNC cytogenetic band: 6p22.1HIST1H4H Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M026281: view genomic region
(about GC identifiers)
Start:
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26,281,283 bp from pter |
End:
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26,285,762 bp from pter |
Size:
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4,480 bases |
Orientation:
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minus strand |
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Proteins
for HIST1H4H gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: H4_HUMAN, P62805 (See
protein sequence)Recommended Name: Histone H4 Size: 103 amino acids; 11367 Da
Subunit: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in oneH3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA
Subcellular location: Nucleus. Chromosome
Sequence caution: Sequence=AAI28106.1; Type=Frameshift; Positions=3;
6/46 PDB 3D structures from  and Proteopedia  for HIST1H4H (see all 46):2BQZ (3D)
2CV5 (3D)
2LVM (3D)
2RNY (3D)
2RS9 (3D)
3A6N (3D)
Secondary accessions: A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7Explore the universe of human proteins at neXtProt for HIST1H4H: NX_P62805
Post-translational modifications:
Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of thegenome but not in heterochromatin1
Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation1
Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylationat Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4(H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage1
Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed bySET8. Trimethylation is performed by SUV420H1 and SUV420H2 and induces gene silencing1
Phosphorylated by PAK2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histonechaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H41
Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interactionbetween histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histoneH4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it mayfunction as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21methylation (H4K20me)1
Sumoylated, which is associated with transcriptional repression1
Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells,including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks activepromoters and enhancers and confers resistance to transcriptional repressors. It is also associated withpost-meiotically activated genes on autosomes1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P62805
HIST1H4H Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003534.1
ENSEMBL proteins: ENSP00000366956 ENSP00000289352 Reactome Protein details: P62805
Human Recombinant Protein Products for HIST1H4H:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
HIST1H4H for ontologies About GeneDecksing
HIST1H4H Antibody Products:
Assay Products for HIST1H4H: |
Protein
Domains /
Families
for HIST1H4H gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HIST1H4H for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P62805ProtoNet protein and cluster: P62805 UniProtKB/Swiss-Prot: H4_HUMAN, P62805Similarity: Belongs to the histone H4 family |
Function
for HIST1H4H gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: H4_HUMAN, P62805Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodeling Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
HIST1H4H for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H4H (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H4H
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: HIST1H4H (NM_003543) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HIST1H4H | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HIST1H4H |
|
Pathways & Interactions
for HIST1H4H gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signal transduction Activin A signaling regulation | | | 2 | Transcription_Sin3 and NuRD in transcription regulation | | | 3 | Development_Notch Signaling Pathway | | | 4 | Development NOTCH1-mediated pathway for NF-KB activity modulation | | | 5 | Type II interferon signaling (IFNG) | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5 EMD Millipore Pathways for HIST1H4H
2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for HIST1H4H
4  GeneGo (Thomson Reuters) Pathways for HIST1H4H
2  BioSystems Pathways for HIST1H4H
5/17 
Reactome Pathways for HIST1H4H (see all 17)
1 
Kegg Pathway (Kegg details for HIST1H4H):
HIST1H4H for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HIST1H4H
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/604 Interacting proteins for HIST1H4H (P628051, 2, 3 ENSP000002893524) via UniProtKB, MINT, STRING, and/or I2D (see all 604)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000723 | telomere maintenance |
-- | -- | | GO:0006325 | chromatin organization |
-- | -- | | GO:0006334 | nucleosome assembly |
-- | -- | | GO:0034080 | CENP-A containing nucleosome assembly at centromere |
-- | -- | | GO:0045653 | negative regulation of megakaryocyte differentiation |
-- | -- |
HIST1H4H for ontologies About GeneDecksing
|
Drugs & Compounds
for HIST1H4H gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for HIST1H4H
Search CenterWatch for drugs/clinical trials and news about HIST1H4H / H4
|
Transcripts
for HIST1H4H gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HIST1H4H gene: NM_003543.3 Unigene Cluster for HIST1H4H: Histone cluster 1, H4h Hs.591790 [show with all ESTs]Unigene Representative Sequence: CD0504392 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000377727(uc003nhm.2) ENST00000289352(uc003nhl.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H4H (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H4H
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: HIST1H4H (NM_003543) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HIST1H4H | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HIST1H4H |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HIST1H4H
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat HIST1H4H | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST1H4H | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST1H4H |
Additional cDNA sequence: BC120939.2 CR542169.1 CR542187.1 3 DOTS entries: DT.405495 DT.101970378 DT.91717593 24/59 AceView cDNA sequences (see all 59): BC010926 AI184259 NM_003543 AI089974 BX117028 BQ302851 BF513750 BX644367 AI539413 BQ302854 AI682486 CF129654 AI637510 CR542169 CD368728 AI141770 BF911505 BG221558 AA702781 CB048803 AW025566 BG678200 CR542187 AI939319
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for HIST1H4H About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b |
|---|
|
| SP1: | | | | | | | | | - | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | | | | |
ECgene alternative splicing isoforms for HIST1H4H
|
Expression
for HIST1H4H gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HIST1H4H expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See HIST1H4H Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HIST1H4H
SOURCE GeneReport for Unigene cluster: Hs.591790
SABiosciences Custom PCR Arrays for HIST1H4H
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HIST1H4H
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat HIST1H4H | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST1H4H | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST1H4H |
Orthologs
for HIST1H4H gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals and fungi.
Orthologs for HIST1H4H gene from 6/14 species (see all 14) About this table
ENSEMBL Gene Tree for HIST1H4H (if available)
TreeFam Gene Tree for HIST1H4H (if available) |
Paralogs
for HIST1H4H gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for HIST1H4H gene
- HIST1H4E1 2 HIST1H4A1 2 HIST1H4D1 2 HIST1H4F1 2 HIST1H4K1 2 HIST1H4B1 2 HIST1H4J1 2 HIST1H4I1 2
- HIST2H4A1 2 HIST2H4B1 2 HIST1H4C1 2 HIST4H41 2 HIST1H4L1 2 HIST1H4G2
14 SIMAP similar genes for HIST1H4H using alignment to 2 protein entries: H4_HUMAN (see all proteins):HIST1H4J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E
HIST1H4F HIST1H4I HIST1H4K HIST1H4L HIST2H4A HIST2H4B
HIST4H4 HIST1H4G
HIST1H4H for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for HIST1H4H
PGOHUM00000232993 PGOHUM00000263308
|
Genomic Variants
for HIST1H4H gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HIST1H4H (26281283 - 26285762 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for HIST1H4H: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HIST1H4H |
|
Disorders
/ Diseases
for HIST1H4H gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HIST1H4H for disorders About GeneDecksing
OMIM gene information: 602828
OMIM disorders: --
7  diseases for HIST1H4H: About MalaCardsnon-hodgkin lymphoma systemic lupus erythematosus lupus erythematosus hodgkin's lymphoma
hepatocellular carcinoma immunodeficiency carcinoma
1 disease from the University of Copenhagen DISEASES database for HIST1H4H:Cancer Export disorders for HIST1H4H gene to outside databases
|
Publications
for HIST1H4H gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HIST1H4H gene, integrated from 9 sources (see all 53):
(articles sorted by number of sources associating them with HIST1H4H) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human and mouse replication-dependent histone genes. (PubMed id 12408966)1, 2, 3 Marzluff W.F....Maltais L.J. (2002)
- Human histone gene organization: nonregular arrangement within a large cluster. (PubMed id 9119399)1, 2, 3 Albig W.... Doenecke D. (1997)
- The human histone gene cluster at the D6S105 locus. (PubMed id 9439656)1, 2 Albig W. and Doenecke D. (1997)
- A conserved function for the H2A.Z C terminus. (PubMed id 22493515)1 Wratting D....Millar C.B. (2012)
- A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- The interaction between ubiquitin C-terminal hydrolas e 37 and glucose-regulated protein 78 in hepatocellular carcinoma. (PubMed id 21800051)1 Fang Y....Shen X. (2012)
- Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF). (PubMed id 21907836)1 Zhao J....Yang P. (2011)
- Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. (PubMed id 21925322)2 Tan M.... Zhao Y. (2011)
- Phosphorylation of H4 Ser 47 promotes HIRA-mediated nucleosome assembly. (PubMed id 21724829)2 Kang B....Zhang Z. (2011)
|
External Searches for HIST1H4H gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HIST1H4H gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HIST1H4H gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HIST1H4H gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for HIST1H4H | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for HIST1H4H gene:
Search GeneIP for patents involving HIST1H4H
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HIST1H4H gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for HIST1H4H | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HIST1H4H | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HIST1H4H | | | OriGene Protein Over-expression Lysate for HIST1H4H | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HIST1H4H | | OriGene 3'-UTR Clone for HIST1H4H | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H4H | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H4H | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HIST1H4H | | OriGene Custom Protein Services for HIST1H4H | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HIST1H4H | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HIST1H4H | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIST1H4H | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HIST1H4H | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST1H4H | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST1H4H |
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 | | | HIST1H4H Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  |  | | | | Search ThermoFisher Antibodies for HIST1H4H |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HIST1H4H |
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