HIST1H4E Gene
protein-coding GIFtS: 53
GCID: GC06P026204
|
|
histone cluster 1, H4e(Previous names: H4 histone family, member J, histone 1, H4e )
(Previous symbol: H4FJ)
| |
Aliases
for HIST1H4E gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Histone Cluster 1, H4e1 2 | | H4/N3 | | H4FJ1 2 3 5 | | H4/O3 | | H4/J3 | | H4F23 | | H4 Histone Family, Member J1 2 | | H4FA3 | | Histone 1, H4e1 2 | | H4FB3 | | Histone H42 | | H4FC3 | | H4/A3 | | H4FD3 | | H4/B3 | | H4FE3 | | H4/C3 | | H4FG3 | | H4/D3 | | H4FH3 | | H4/E3 | | H4FI3 | | H4/G3 | | H4FK3 | | H4/H3 | | H4FM3 | | H4/I3 | | H4FN3 | | H4/J3 | | H4FO3 | | H4/K3 | | HIST2H43 | | H4/M3 | | |
Export aliases for HIST1H4E gene to outside databasesPrevious GC identifers: GC06P026263 GC06P026312 GC06P026148 |
Summaries
for HIST1H4E gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for HIST1H4E:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber ineukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around whichapproximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts withlinker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene isintronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but insteadcontain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: H4_HUMAN, P62805Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodeling
Gene Wiki entry for HIST1H4E
|
Genomic Views
for HIST1H4E gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HIST1H4E gene promoter:
SRF AML1a SRF (504 AA) Egr-1 Olf-1 XBP-1 Egr-4 GATA-1 FOXO4
Other transcription factors
Search SABiosciences Chromatin IP Primers for HIST1H4E
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIST1H4E |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p22.1 Ensembl cytogenetic band: 6p22.2 HGNC cytogenetic band: 6p22.1HIST1H4E Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P026204: view genomic region
(about GC identifiers)
Start:
|
26,204,858 bp from pter |
End:
|
26,206,266 bp from pter |
Size:
|
1,409 bases |
Orientation:
|
plus strand |
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Proteins
for HIST1H4E gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: H4_HUMAN, P62805 (See
protein sequence)Recommended Name: Histone H4 Size: 103 amino acids; 11367 Da
Subunit: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in oneH3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA
Subcellular location: Nucleus. Chromosome
Sequence caution: Sequence=AAI28106.1; Type=Frameshift; Positions=3;
6/46 PDB 3D structures from  and Proteopedia  for HIST1H4E (see all 46):2BQZ (3D)
2CV5 (3D)
2LVM (3D)
2RNY (3D)
2RS9 (3D)
3A6N (3D)
Secondary accessions: A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7Explore the universe of human proteins at neXtProt for HIST1H4E: NX_P62805
Post-translational modifications:
Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of thegenome but not in heterochromatin1
Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation1
Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylationat Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4(H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage1
Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed bySET8. Trimethylation is performed by SUV420H1 and SUV420H2 and induces gene silencing1
Phosphorylated by PAK2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histonechaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H41
Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interactionbetween histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histoneH4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it mayfunction as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21methylation (H4K20me)1
Sumoylated, which is associated with transcriptional repression1
Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells,including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks activepromoters and enhancers and confers resistance to transcriptional repressors. It is also associated withpost-meiotically activated genes on autosomes1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P62805
HIST1H4E Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003536.1
ENSEMBL proteins: ENSP00000353624 Reactome Protein details: P62805
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
HIST1H4E for ontologies About GeneDecksing
HIST1H4E Antibody Products:
Assay Products for HIST1H4E: |
Protein
Domains /
Families
for HIST1H4E gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HIST1H4E for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P62805ProtoNet protein and cluster: P62805 UniProtKB/Swiss-Prot: H4_HUMAN, P62805Similarity: Belongs to the histone H4 family |
Function
for HIST1H4E gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: H4_HUMAN, P62805Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodeling
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H4E
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H4E
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: HIST1H4E (NM_003545) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HIST1H4E | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HIST1H4E |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
HIST1H4E for ontologies About GeneDecksing
|
Pathways & Interactions
for HIST1H4E gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signal transduction Activin A signaling regulation | | | 2 | Transcription_Sin3 and NuRD in transcription regulation | | | 3 | Development_Notch Signaling Pathway | | | 4 | Development NOTCH1-mediated pathway for NF-KB activity modulation | | | 5 | Type II interferon signaling (IFNG) | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5 EMD Millipore Pathways for HIST1H4E
2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for HIST1H4E
4  GeneGo (Thomson Reuters) Pathways for HIST1H4E
2  BioSystems Pathways for HIST1H4E
5/17 
Reactome Pathways for HIST1H4E (see all 17)
1 
Kegg Pathway (Kegg details for HIST1H4E):
HIST1H4E for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HIST1H4E
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/604 Interacting proteins for HIST1H4E (P628051, 2, 3 ENSP000003536244) via UniProtKB, MINT, STRING, and/or I2D (see all 604)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000723 | telomere maintenance |
-- | -- | | GO:0006325 | chromatin organization |
-- | -- | | GO:0006334 | nucleosome assembly |
-- | -- | | GO:0034080 | CENP-A containing nucleosome assembly at centromere |
-- | -- | | GO:0045653 | negative regulation of megakaryocyte differentiation |
-- | -- |
HIST1H4E for ontologies About GeneDecksing
|
Drugs & Compounds
for HIST1H4E gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for HIST1H4E
Search CenterWatch for drugs/clinical trials and news about HIST1H4E / H4
|
Transcripts
for HIST1H4E gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HIST1H4E gene: NM_003545.3 Unigene Cluster for HIST1H4E: Histone cluster 1, H4e Hs.662174 [show with all ESTs]Unigene Representative Sequence: BF6732321 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000360441(uc003ngy.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H4E
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H4E
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: HIST1H4E (NM_003545) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HIST1H4E | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HIST1H4E |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HIST1H4E
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat HIST1H4E | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST1H4E | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST1H4E |
Additional cDNA sequence: AK312153.1 CR542180.1 CR542189.1 1 DOTS entry: DT.440599 22 AceView cDNA sequences: BC012587 BQ067875 CR542180 BC056868 NM_003545 BX280884 AA379443 CR542189 BC050615 AW963932 BI756282 AW512812 BI834372 AI221390 BU660715 AI985605 AW002185 AA578323 BU753081 BF673232 AA608930 BQ311536
GeneLoc Exon Structure
|
Expression
for HIST1H4E gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HIST1H4E expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See HIST1H4E Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HIST1H4E
SOURCE GeneReport for Unigene cluster: Hs.662174
SABiosciences Custom PCR Arrays for HIST1H4E
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HIST1H4E
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat HIST1H4E | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST1H4E | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST1H4E |
Orthologs
for HIST1H4E gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals and fungi.
Orthologs for HIST1H4E gene from 4/11 species (see all 11) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
H41 |
germinal histone H4 gene |
82.2(n)
100(a) |
|
417946 NM_001037845.1 NP_001032934.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufe37d092 |
Transcribed sequence with strong similarity to protein more |
82.55(n) |
|
57061812 |
fruit fly
(Drosophila melanogaster) |
Insecta |
His4:CG338771 |
CG33877-PA |
79.94(n)
98.06(a) |
|
3772211 NM_001032191.1 NP_001027362.1 |
A. gossypii yeast
(Ashbya gossypii) |
Saccharomycetes |
AGOS_AER012C1 |
AER012Cp |
77.02(n)
90.29(a) |
|
4621072 NM_210226.1 NP_984872.1 |
ENSEMBL Gene Tree for HIST1H4E (if available)
TreeFam Gene Tree for HIST1H4E (if available) |
Paralogs
for HIST1H4E gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for HIST1H4E gene
- HIST1H4H1 2 HIST1H4K1 2 HIST1H4J1 2 HIST1H4I1 2 HIST1H4D1 2 HIST1H4B1 2 HIST1H4A1 2 HIST1H4L1 2
- HIST4H41 2 HIST2H4A1 2 HIST2H4B1 2 HIST1H4F1 2 HIST1H4C1 2 HIST1H4G2
3 SIMAP similar genes for HIST1H4E using alignment to 1 protein entry: H4_HUMAN:HIST1H4J HIST1H4H HIST1H4G
HIST1H4E for paralogs About GeneDecksing
|
Genomic Variants
for HIST1H4E gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HIST1H4E (26204858 - 26206266 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for HIST1H4E
1 CNV: 51865 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HIST1H4E |
|
Disorders
/ Diseases
for HIST1H4E gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HIST1H4E for disorders About GeneDecksing
OMIM gene information: 602830
OMIM disorders: --
7  diseases for HIST1H4E: About MalaCardsnon-hodgkin lymphoma systemic lupus erythematosus lupus erythematosus hodgkin's lymphoma
hepatocellular carcinoma immunodeficiency carcinoma
1 disease from the University of Copenhagen DISEASES database for HIST1H4E:Cancer Export disorders for HIST1H4E gene to outside databases
|
Publications
for HIST1H4E gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HIST1H4E gene, integrated from 9 sources (see all 54):
(articles sorted by number of sources associating them with HIST1H4E) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human and mouse replication-dependent histone genes. (PubMed id 12408966)1, 2, 3 Marzluff W.F....Maltais L.J. (2002)
- Human histone gene organization: nonregular arrangement within a large cluster. (PubMed id 9119399)1, 2, 3 Albig W.... Doenecke D. (1997)
- The human histone gene cluster at the D6S105 locus. (PubMed id 9439656)1, 2 Albig W. and Doenecke D. (1997)
- A conserved function for the H2A.Z C terminus. (PubMed id 22493515)1 Wratting D....Millar C.B. (2012)
- A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- The interaction between ubiquitin C-terminal hydrolas e 37 and glucose-regulated protein 78 in hepatocellular carcinoma. (PubMed id 21800051)1 Fang Y....Shen X. (2012)
- Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF). (PubMed id 21907836)1 Zhao J....Yang P. (2011)
- Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. (PubMed id 21925322)2 Tan M.... Zhao Y. (2011)
- Phosphorylation of H4 Ser 47 promotes HIRA-mediated nucleosome assembly. (PubMed id 21724829)2 Kang B....Zhang Z. (2011)
|
External Searches for HIST1H4E gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HIST1H4E gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HIST1H4E gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HIST1H4E gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for HIST1H4E | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for HIST1H4E gene:
Search GeneIP for patents involving HIST1H4E
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HIST1H4E gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for HIST1H4E | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HIST1H4E | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HIST1H4E | | | OriGene Protein Over-expression Lysate for HIST1H4E | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HIST1H4E | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H4E | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H4E | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HIST1H4E | | OriGene Custom Protein Services for HIST1H4E | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HIST1H4E | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HIST1H4E | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIST1H4E | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HIST1H4E | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST1H4E | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST1H4E |
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 | | | HIST1H4E Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for HIST1H4E |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HIST1H4E |
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