HIST1H2BN Gene
protein-coding GIFtS: 50
GCID: GC06P027805
|
|
histone cluster 1, H2bn(Previous names: H2B histone family, member D, histone 1, H2bn )
(Previous symbol: H2BFD)
| |
Aliases
for HIST1H2BN gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Histone Cluster 1, H2bn1 2 | | Histone 1, H2bn1 2 | | H2BFD1 2 3 5 | | Histone H2B.D2 3 | | H2B/D1 | | Histone H2B Type 1-N2 | | H2B Histone Family, Member D1 2 | | |
Export aliases for HIST1H2BN gene to outside databasesPrevious GC identifers: GC06P027864 GC06P027914 GC06P027913 GC06P027614 |
Summaries
for HIST1H2BN gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for HIST1H2BN:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber ineukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around whichapproximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts withlinker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene isintronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but insteadcontain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome6p22-p21.3. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: H2B1N_HUMAN, Q99877Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodeling
Gene Wiki entry for HIST1H2BN
|
Genomic Views
for HIST1H2BN gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HIST1H2BN gene promoter:
AML1a XBP-1 CUTL1 Arnt E47 HEN1 CREB FOXO4 deltaCREB SEF-1 (1)
Other transcription factors
Search SABiosciences Chromatin IP Primers for HIST1H2BN
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIST1H2BN |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p22.1 Ensembl cytogenetic band: 6p22.1 HGNC cytogenetic band: 6p22.1HIST1H2BN Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P027805: view genomic region
(about GC identifiers)
Start:
|
27,806,323 bp from pter |
End:
|
27,819,974 bp from pter |
Size:
|
13,652 bases |
Orientation:
|
plus strand |
|
Proteins
for HIST1H2BN gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: H2B1N_HUMAN, Q99877 (See
protein sequence)Recommended Name: Histone H2B type 1-N Size: 126 amino acids; 13922 Da
Subunit: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in oneH3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA
Subcellular location: Nucleus. Chromosome
Secondary accessions: B2R5L4 Q494S8 Q96FB7Explore the universe of human proteins at neXtProt for HIST1H2BN: NX_Q99877
Post-translational modifications:
Monoubiquitination at Lys-35 (H2BK34Ub) by the MSL1/MSL2 dimer is required for histone H3 'Lys-4' (H3K4me) and 'Lys-79'(H3K79me) methylation and transcription activation at specific gene loci, such as HOXA9 and MEIS1 loci. Similarly,monoubiquitination at Lys-121 (H2BK120Ub) by the RNF20/40 complex gives a specific tag for epigenetic transcriptionalactivation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It also functions cooperativelywith the FACT dimer to stimulate elongation by RNA polymerase II1
Phosphorylation at Ser-37 (H2BS36ph) by AMPK in response to stress promotes transcription (By similarity).Phosphorylated on Ser-15 (H2BS14ph) by STK4/MST1 during apoptosis; which facilitates apoptotic chromatin condensation.Also phosphorylated on Ser-15 in response to DNA double strand breaks (DSBs), and in correlation with somatichypermutation and immunoglobulin class-switch recombination1
GlcNAcylation at Ser-113 promotes monoubiquitination of Lys-121. It fluctuates in response to extracellular glucose,and associates with transcribed genes (By similarity)1
Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells,including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks activepromoters and enhancers and confers resistance to transcriptional repressors. It is also associated withpost-meiotically activated genes on autosomes1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q99877
HIST1H2BN Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003511.1
ENSEMBL proteins: ENSP00000446031 ENSP00000380177 Reactome Protein details: Q99877
Human Recombinant Protein Products for HIST1H2BN:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
HIST1H2BN for ontologies About GeneDecksing
HIST1H2BN Antibody Products:
Assay Products for HIST1H2BN: |
Protein
Domains /
Families
for HIST1H2BN gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HIST1H2BN for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q99877ProtoNet protein and cluster: Q99877 UniProtKB/Swiss-Prot: H2B1N_HUMAN, Q99877Similarity: Belongs to the histone H2B family |
Function
for HIST1H2BN gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: H2B1N_HUMAN, Q99877Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodeling Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
HIST1H2BN for ontologies About GeneDecksing
Phenotypes:
3 GenomeRNAi human phenotypes for HIST1H2BN:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H2BN (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H2BN
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: HIST1H2BN (NM_003520) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HIST1H2BN | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HIST1H2BN |
|
Pathways & Interactions
for HIST1H2BN gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Meiotic Synapsis | | | 2 | RSF Complex Binds the Centromere. | | | 3 | Signal transduction Activin A signaling regulation | | | 4 | Formation of Meiotic Holliday Junction | | | 5 | Disease | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for HIST1H2BN
1  GeneGo (Thomson Reuters) Pathway for HIST1H2BN
1  BioSystems Pathway for HIST1H2BN
5/17 
Reactome Pathways for HIST1H2BN (see all 17)
1 
Kegg Pathway (Kegg details for HIST1H2BN):
HIST1H2BN for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HIST1H2BN
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
5/11 Interacting proteins for HIST1H2BN (Q998773 ENSP000003801774) via UniProtKB, MINT, STRING, and/or I2D (see all 11)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table
HIST1H2BN for ontologies About GeneDecksing
|
Drugs & Compounds
for HIST1H2BN gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for HIST1H2BN
Search CenterWatch for drugs/clinical trials and news about HIST1H2BN / H2B1N
|
Transcripts
for HIST1H2BN gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HIST1H2BN gene: NM_003520.3 Unigene Cluster for HIST1H2BN: Histone cluster 1, H2bn Hs.673851 Unigene Representative Sequence: NM_0035202 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000449538(uc003njt.1 uc003nju.1) ENST00000396980(uc003njv.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H2BN (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H2BN
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: HIST1H2BN (NM_003520) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HIST1H2BN | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HIST1H2BN |
Additional cDNA sequence: BC101411.1 BC101412.1 BC101413.1 1 DOTS entry: DT.40223907 18 AceView cDNA sequences: BX118795 AK130106 BX103372 NM_003520 AI379440 BC009783 BC011372 BX106896 CA310244 AA505876 AA354035 AI217639 AA873858 BM834753 AA995300 BE543494 BM994942 BF238762
GeneLoc Exon Structure
|
Expression
for HIST1H2BN gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HIST1H2BN expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See HIST1H2BN Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HIST1H2BN
SOURCE GeneReport for Unigene cluster: Hs.673851
SABiosciences Custom PCR Arrays for HIST1H2BN
Primer
Products: | | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HIST1H2BN | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST1H2BN | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST1H2BN |
Orthologs
for HIST1H2BN gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for HIST1H2BN gene from 4/12 species (see all 12) About this table
ENSEMBL Gene Tree for HIST1H2BN (if available)
TreeFam Gene Tree for HIST1H2BN (if available) |
Paralogs
for HIST1H2BN gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for HIST1H2BN gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HIST1H2BN (27806323 - 27819974 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for HIST1H2BN: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HIST1H2BN |
|
Disorders
/ Diseases
for HIST1H2BN gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HIST1H2BN for disorders About GeneDecksing
OMIM gene information: 602801
OMIM disorders: --
3  diseases for HIST1H2BN: About MalaCardssystemic lupus erythematosus lupus erythematosus immunodeficiency
Export disorders for HIST1H2BN gene to outside databases
|
Publications
for HIST1H2BN gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HIST1H2BN gene, integrated from 9 sources (see all 27):
(articles sorted by number of sources associating them with HIST1H2BN) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human and mouse replication-dependent histone genes. (PubMed id 12408966)1, 2, 3 Marzluff W.F....Maltais L.J. (2002)
- The human histone gene cluster at the D6S105 locus. (PubMed id 9439656)1, 2, 3 Albig W. and Doenecke D. (1997)
- Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. (PubMed id 16713563)1, 2 Pavri R....Reinberg D. (2006)
- Quantitative proteomic analysis of post-translational modifications of human histones. (PubMed id 16627869)1, 2 Beck H.C.... Jensen O.N. (2006)
- Inhibition of core histones acetylation by carcinogenic nickel(II). (PubMed id 16283522)1, 2 Golebiowski F. and Kasprzak K.S. (2005)
- Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. (PubMed id 16307923)1, 2 Zhu B.... Reinberg D. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. (PubMed id 12757711)1, 2 Cheung W.L.... Allis C.D. (2003)
- Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)
|
External Searches for HIST1H2BN gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HIST1H2BN gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HIST1H2BN gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HIST1H2BN gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for HIST1H2BN | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for HIST1H2BN gene:
Search GeneIP for patents involving HIST1H2BN
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HIST1H2BN gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for HIST1H2BN | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HIST1H2BN | | Browse OriGene genome-wide validated SYBR primer pairs | | | OriGene Protein Over-expression Lysate for HIST1H2BN | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HIST1H2BN | | OriGene 3'-UTR Clone for HIST1H2BN | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H2BN | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H2BN | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HIST1H2BN | | OriGene Custom Protein Services for HIST1H2BN | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HIST1H2BN | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HIST1H2BN | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIST1H2BN | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HIST1H2BN | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST1H2BN | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST1H2BN |
| |
 |  |  |  | |
| | | |  |  |  |  | | | | |
 |
 |
 |
 | | | HIST1H2BN Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HIST1H2BN |
| |  | |
|
|
|
