Aliases for HIST1H2BJ Gene
Aliases for HIST1H2BJ Gene
External Ids for HIST1H2BJ Gene
- HGNC: 4761
- Entrez Gene: 8970
- Ensembl: ENSG00000124635
- OMIM: 615044
- UniProtKB: P06899
Previous HGNC Symbols for HIST1H2BJ Gene
- H2BFR
Previous GeneCards Identifiers for HIST1H2BJ Gene
- GC06M027158
- GC06M027208
- GC06M027100
- GC06M026910
- GC06M027096
Summaries for HIST1H2BJ Gene
-
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015]
GeneCards Summary for HIST1H2BJ Gene
HIST1H2BJ (Histone Cluster 1 H2B Family Member J) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BK.
UniProtKB/Swiss-Prot for HIST1H2BJ Gene
-
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
-
Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HIST1H2BJ Gene
Genomics for HIST1H2BJ Gene
Regulatory Element Products
Genomic Location for HIST1H2BJ Gene
- Chromosome:
- 6
- Start:
- 27,125,897 bp from pter
- End:
- 27,132,796 bp from pter
- Size:
- 6,900 bases
- Orientation:
- Minus strand
Genomic View for HIST1H2BJ Gene
Genes around HIST1H2BJ on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.1 by Ensembl
- 6p22.1 by Entrez Gene
- 6p22.1 by HGNC
HIST1H2BJ Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HIST1H2BJ Gene
Proteins for HIST1H2BJ Gene
-
Protein details for HIST1H2BJ Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P06899-H2B1J_HUMAN
- Recommended name:
- Histone H2B type 1-J
- Protein Accession:
- P06899
- B2R4J4
- O60816
Protein attributes for HIST1H2BJ Gene
- Size:
- 126 amino acids
- Molecular mass:
- 13904 Da
- Quaternary structure:
-
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Protein Expression for HIST1H2BJ Gene
Post-translational modifications for HIST1H2BJ Gene
- Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells, including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. It is also associated with post-meiotically activated genes on autosomes.
- GlcNAcylation at Ser-113 promotes monoubiquitination of Lys-121. It fluctuates in response to extracellular glucose, and associates with transcribed genes (By similarity).
- Monoubiquitination at Lys-35 (H2BK34Ub) by the MSL1/MSL2 dimer is required for histone H3 Lys-4 (H3K4me) and Lys-79 (H3K79me) methylation and transcription activation at specific gene loci, such as HOXA9 and MEIS1 loci. Similarly, monoubiquitination at Lys-121 (H2BK120Ub) by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 Lys-4 and Lys-79 methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II. H2BK120Ub also acts as a regulator of mRNA splicing: deubiquitination by USP49 is required for efficient cotranscriptional splicing of a large set of exons.
- Phosphorylation at Ser-37 (H2BS36ph) by AMPK in response to stress promotes transcription (By similarity). Phosphorylated on Ser-15 (H2BS14ph) by STK4/MST1 during apoptosis; which facilitates apoptotic chromatin condensation. Also phosphorylated on Ser-15 in response to DNA double strand breaks (DSBs), and in correlation with somatic hypermutation and immunoglobulin class-switch recombination.
- Ubiquitination at posLast=121121
- Glycosylation at posLast=113113
- Modification sites at PhosphoSitePlus
Other Protein References for HIST1H2BJ Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Abcam antibodies for HIST1H2BJ
- Invitrogen Antibodies for HIST1H2BJ
- Search GeneTex for Antibodies for HIST1H2BJ
Protein Products
-
OriGene Purified Proteins for HIST1H2BJ
- Search Origene for MassSpec and Protein Over-expression Lysates for HIST1H2BJ
- Origene Custom Protein Services for HIST1H2BJ
- Search GeneTex for Proteins for HIST1H2BJ
Assay Products
No data available for DME Specific Peptides for HIST1H2BJ Gene
Domains & Families for HIST1H2BJ Gene
Gene Families for HIST1H2BJ Gene
- HGNC:
Protein Domains for HIST1H2BJ Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for HIST1H2BJ Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P06899- Family:
-
- Belongs to the histone H2B family.
Function for HIST1H2BJ Gene
Molecular function for HIST1H2BJ Gene
- UniProtKB/Swiss-Prot Function:
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
- UniProtKB/Swiss-Prot Function:
- Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001530 | lipopolysaccharide binding | IDA | 11859126 |
| GO:0003677 | DNA binding | NAS,IBA | 6647026 |
| GO:0046982 | protein heterodimerization activity | IEA | -- |
Phenotypes for HIST1H2BJ Gene
- MGI mutant phenotypes for HIST1H2BJ:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for HIST1H2BJ:
Animal Models for HIST1H2BJ Gene
- MGI Knock Outs for HIST1H2BJ:
-
- Hist2h2be tm1Dlc
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for HIST1H2BJ gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HIST1H2BJ gene
- Search ViGene Biosciences for HIST1H2BJ
CRISPR Products
-
OriGene CRISPR knockouts for HIST1H2BJ
-
Santa Cruz Biotechnology (SCBT) CRISPR for HIST1H2BJ
- GenScript: Design CRISPR guide RNA sequences for HIST1H2BJ
miRNA for HIST1H2BJ Gene
- miRTarBase miRNAs that target HIST1H2BJ
-
- hsa-mir-34a-5p (MIRT025460)
- hsa-mir-98-5p (MIRT027525)
- hsa-mir-320b (MIRT036239)
- hsa-mir-652-3p (MIRT039545)
- hsa-mir-615-3p (MIRT039638)
- hsa-mir-320a (MIRT044806)
- hsa-mir-186-5p (MIRT045085)
- hsa-mir-138-5p (MIRT045836)
- hsa-mir-129-5p (MIRT048046)
- hsa-mir-31-5p (MIRT049894)
- hsa-mir-3176 (MIRT052790)
- hsa-mir-498 (MIRT676167)
- hsa-mir-4279 (MIRT676168)
- hsa-mir-6778-3p (MIRT676169)
- hsa-mir-1976 (MIRT676170)
- hsa-mir-3653-5p (MIRT676171)
- hsa-mir-5695 (MIRT676172)
- hsa-mir-1281 (MIRT676173)
- hsa-mir-6747-3p (MIRT676174)
- hsa-mir-6727-3p (MIRT676175)
- hsa-mir-4722-3p (MIRT676176)
- hsa-mir-4726-3p (MIRT676177)
- hsa-mir-6764-5p (MIRT676178)
- hsa-mir-1915-3p (MIRT676179)
- hsa-mir-6840-3p (MIRT676180)
- hsa-mir-3691-3p (MIRT676181)
- hsa-mir-5697 (MIRT676182)
- hsa-mir-562 (MIRT676183)
- hsa-mir-4435 (MIRT689819)
- hsa-mir-24-3p (MIRT689820)
- hsa-mir-4284 (MIRT689821)
- hsa-mir-4755-3p (MIRT689822)
- hsa-mir-3922-3p (MIRT689823)
- hsa-mir-3190-5p (MIRT689824)
- hsa-mir-342-3p (MIRT689825)
- hsa-mir-4267 (MIRT689826)
- hsa-mir-338-3p (MIRT689827)
- hsa-mir-4530 (MIRT689828)
- hsa-mir-5693 (MIRT689829)
- hsa-mir-1228-3p (MIRT689830)
- hsa-mir-6878-3p (MIRT689831)
- hsa-mir-6744-3p (MIRT689832)
- hsa-mir-4757-5p (MIRT689833)
- hsa-mir-5589-5p (MIRT689834)
- hsa-mir-4731-5p (MIRT689835)
- hsa-mir-4312 (MIRT689836)
- hsa-mir-150-5p (MIRT689837)
- hsa-mir-4304 (MIRT689838)
- hsa-mir-212-5p (MIRT689839)
- hsa-mir-186-3p (MIRT689840)
- hsa-mir-520h (MIRT689841)
- hsa-mir-520g-3p (MIRT689842)
- hsa-mir-512-3p (MIRT689843)
- hsa-mir-520e (MIRT689844)
- hsa-mir-520d-3p (MIRT689845)
- hsa-mir-520c-3p (MIRT689846)
- hsa-mir-520b (MIRT689847)
- hsa-mir-520a-3p (MIRT689848)
- hsa-mir-373-3p (MIRT689849)
- hsa-mir-372-3p (MIRT689850)
- hsa-mir-302e (MIRT689851)
- hsa-mir-302d-3p (MIRT689852)
- hsa-mir-302c-3p (MIRT689853)
- hsa-mir-302b-3p (MIRT689854)
- hsa-mir-302a-3p (MIRT689855)
- hsa-mir-93-5p (MIRT689856)
- hsa-mir-526b-3p (MIRT689857)
- hsa-mir-519d-3p (MIRT689858)
- hsa-mir-20b-5p (MIRT689859)
- hsa-mir-20a-5p (MIRT689860)
- hsa-mir-17-5p (MIRT689861)
- hsa-mir-106b-5p (MIRT689862)
- hsa-mir-106a-5p (MIRT689863)
miRNA Products
- Search ViGene Biosciences for HIST1H2BJ
Inhibitory RNA Products
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-
ViGene Biosciences ready-to-package AAV shRNAs for HIST1H2BJ gene
Clone Products
-
OriGene ORF clones in human for HIST1H2BJ
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for HIST1H2BJ
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for HIST1H2BJ
Cell Line Products
-
Horizon Cell Lines for HIST1H2BJ
-
ViGene Biosciences adenoviral particle packaged cDNA for HIST1H2BJ gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HIST1H2BJ gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HIST1H2BJ gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HIST1H2BJ Gene
Localization for HIST1H2BJ Gene
Subcellular locations from UniProtKB/Swiss-Prot for HIST1H2BJ Gene
- Nucleus. Chromosome.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
| cytosol | 4 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000786 | nucleosome | NAS | 6647026 |
| GO:0005615 | extracellular space | IDA | 11859126 |
| GO:0005634 | nucleus | IDA | 16319397 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005694 | chromosome | IEA | -- |
Pathways & Interactions for HIST1H2BJ Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 |
.88
|
.34
|
| 2 | DNA Double-Strand Break Repair |
.53
|
|
| 3 | Cellular Senescence | ||
| 4 | Chromosome Maintenance | ||
| 5 | Cell Cycle, Mitotic |
.83
|
.60
|
Pathways by source for HIST1H2BJ Gene
68 Reactome pathways for HIST1H2BJ Gene
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Activation of HOX genes during differentiation
- Amyloid fiber formation
- B-WICH complex positively regulates rRNA expression
3 KEGG pathways for HIST1H2BJ Gene
1 GeneGo (Thomson Reuters) pathway for HIST1H2BJ Gene
Interacting Proteins for HIST1H2BJ Gene
Selected Interacting proteins:
ENSP00000342886
P06899-H2B1J_HUMAN
for HIST1H2BJ Gene via
STRING
MINT
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002227 | innate immune response in mucosa | IDA | 12860195 |
| GO:0006334 | nucleosome assembly | NAS | 6647026 |
| GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway | IDA | 11859126 |
| GO:0016567 | protein ubiquitination | TAS | -- |
| GO:0019731 | antibacterial humoral response | IDA | 12860195 |
No data available for SIGNOR curated interactions for HIST1H2BJ Gene
Transcripts for HIST1H2BJ Gene
mRNA/cDNA for HIST1H2BJ Gene
- (1) REFSEQ mRNAs :
- (0) Additional mRNA sequences :
- -
- (253) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HIST1H2BJ Gene
CRISPR Products
-
OriGene CRISPR knockouts for HIST1H2BJ
-
Santa Cruz Biotechnology (SCBT) CRISPR for HIST1H2BJ
- GenScript: Design CRISPR guide RNA sequences for HIST1H2BJ
miRNA Products
- Search ViGene Biosciences for HIST1H2BJ
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HIST1H2BJ
- Browse OriGene Inhibitory RNA Products For HIST1H2BJ
-
ViGene Biosciences ready-to-package AAV shRNAs for HIST1H2BJ gene
Clone Products
-
OriGene ORF clones in human for HIST1H2BJ
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- Addgene plasmids for HIST1H2BJ
Flow Cytometry Products
Expression for HIST1H2BJ Gene
mRNA differential expression in normal tissues according to GTEx for HIST1H2BJ Gene
This gene is overexpressed in Whole Blood (x11.1) and Testis (x7.0).
This gene is overexpressed in Saliva (56.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for HIST1H2BJ Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of HIST1H2BJ Gene:
HIST1H2BJSOURCE GeneReport for Unigene cluster for HIST1H2BJ Gene:
Hs.656567Evidence on tissue expression from TISSUES for HIST1H2BJ Gene
- Nervous system(4.2)
Primer Products
-
OriGene qPCR primer pairs for HIST1H2BJ
-
OriGene qPCR primer pairs and template standards for HIST1H2BJ
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HIST1H2BJ Gene
Orthologs for HIST1H2BJ Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| dog (Canis familiaris) |
Mammalia | HIST1H2BJ 35 |
|
OneToOne | |
| LOC488288 34 |
|
||||
| chimpanzee (Pan troglodytes) |
Mammalia | HIST1H2BJ 35 |
|
OneToOne | |
| HIST1H2BK 34 |
|
||||
| cow (Bos Taurus) |
Mammalia | HIST1H2BJ 35 |
|
OneToOne | |
| LOC522960 34 |
|
||||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
ManyToMany | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
ManyToMany | |
| mouse (Mus musculus) |
Mammalia | Hist2h2be 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Hist2h2be 34 |
|
||
| chicken (Gallus gallus) |
Aves | -- 35 |
|
ManyToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
ManyToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC100487485 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | zgc:194989 35 |
|
ManyToMany | |
| wu:fe11b02 35 35 35 35 35 35 35 35 |
|
ManyToMany | |||
| ano9a 35 35 |
|
ManyToMany | |||
| zgc:171759 35 35 35 35 35 35 35 35 35 35 |
|
ManyToMany | |||
| CABZ01086354.1 35 |
|
ManyToMany | |||
| si:dkey-261m9.19 35 |
|
ManyToMany | |||
| si:dkey-261m9.6 35 |
|
ManyToMany | |||
| zgc:112234 35 35 35 35 35 |
|
ManyToMany | |||
| zgc:173587 35 |
|
ManyToMany | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | H2B_ANOGA_e 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | His2B:CG33884 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | his-54 34 |
|
- Species where no ortholog for HIST1H2BJ was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for HIST1H2BJ Gene
Paralogs for HIST1H2BJ Gene
(23) SIMAP similar genes for HIST1H2BJ Gene using alignment to 2 proteins:
Pseudogenes.org Pseudogenes for HIST1H2BJ Gene
Variants for HIST1H2BJ Gene
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000107163 | -- | 27,131,958(+) | ACCGT(A/G)GACTT | downstream-variant-500B, upstream-variant-2KB | |
| rs1001283944 | -- | 27,133,597(+) | CAAGA(C/T)TCTAG | downstream-variant-500B, upstream-variant-2KB | |
| rs1001313399 | -- | 27,133,468(+) | AACTA(C/T)CTGTA | upstream-variant-2KB, utr-variant-3-prime | |
| rs1002289581 | -- | 27,134,532(+) | AACTT(C/T)TGGTG | upstream-variant-2KB | |
| rs1002319247 | -- | 27,134,237(+) | ACTTG(A/C)CAGGA | upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1029124 | CNV | loss | 25217958 |
| nsv965698 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
28.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.87;
18.16% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HIST1H2BJ Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HIST1H2BJ
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HIST1H2BJ Gene
Disorders for HIST1H2BJ Gene
Relevant External Links for HIST1H2BJ
No disorders were found for HIST1H2BJ Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HIST1H2BJ Gene
Publications for HIST1H2BJ Gene
- The human and mouse replication-dependent histone genes. (PMID: 12408966) Marzluff W.F. … Maltais L.J. (Genomics 2002) 2 3 4 64
- The primary structure and expression of four cloned human histone genes. (PMID: 6647026) Zhong R. … Heintz N. (Nucleic Acids Res. 1983) 2 3 4 64
- Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels. (PMID: 19084217) Benyamin B. … Visscher P.M. (Am. J. Hum. Genet. 2009) 3 46 64
- Common variants on chromosome 6p22.1 are associated with schizophrenia. (PMID: 19571809) Shi J. … Gejman P.V. (Nature 2009) 3 46 64
- Quantitative proteomic analysis of post-translational modifications of human histones. (PMID: 16627869) Beck H.C. … Jensen O.N. (Mol. Cell. Proteomics 2006) 3 4 64
Products for HIST1H2BJ Gene
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- GenScript: Next-day shipping cDNA ORF clone for HIST1H2BJ in any vector
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- GenScript Custom Assay Services for HIST1H2BJ
- GenScript Custom overexpressing Cell Line Services for HIST1H2BJ
- GenScript: Design CRISPR guide RNA sequences for HIST1H2BJ
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for HIST1H2BJ
- Sino Biological Human cDNA Clone for HIST1H2BJ
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Invitrogen Antibodies for HIST1H2BJ
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for HIST1H2BJ
- Search GeneTex for Antibodies for HIST1H2BJ
- Search GeneTex for Proteins for HIST1H2BJ
- ViGene Biosciences adenoviral particle packaged cDNA for HIST1H2BJ gene
- ViGene Biosciences lentiviral particle packaged cDNA for HIST1H2BJ gene
- ViGene Biosciences ready-to-package AAV shRNAs for HIST1H2BJ gene
- Search ViGene Biosciences for HIST1H2BJ
- Search Santa Cruz Biotechnology (SCBT) for HIST1H2BJ Antibodies
- Search Santa Cruz Biotechnology (SCBT) for HIST1H2BJ siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HIST1H2BJ
- Horizon Cell Lines for HIST1H2BJ
- Cyagen custom Knockout/knockin (KOKI) mouse models for HIST1H2BJ
- VectorBuilder custom plasmid, inducible vectors for HIST1H2BJ
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HIST1H2BJ
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HIST1H2BJ Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer