HIST1H2BI Gene
protein-coding GIFtS: 51
GCID: GC06P026273
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histone cluster 1, H2bi(Previous names: H2B histone family, member K, histone 1, H2bi ) (Previous symbol: H2BFK)
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Aliases for HIST1H2BI gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Histone Cluster 1, H2bi1 2 | | H2B/H1 | | H2BFK1 2 3 5 | | H2B/L1 | | H2B/K1 | | H2BFA3 | | H2B Histone Family, Member K1 2 | | H2BFG3 | | Histone 1, H2bi1 2 | | H2BFH3 | | Histone H2B.1 A2 3 | | H2BFL3 | | Histone H2B.K2 3 | | Histone H2B.A3 | | Histone H2B Type 1-C/E/F/G/I2 | | Histone H2B.G3 | | H2B/A1 | | Histone H2B.H3 | | H2B/G1 | | Histone H2B.L3 |
Export aliases for HIST1H2BI gene to outside databasesPrevious GC identifers: GC06P026331 GC06P026381 GC06P026219 |
Summaries for HIST1H2BI gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for HIST1H2BI: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber ineukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around whichapproximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts withlinker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene isintronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but insteadcontain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.(provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: H2B1C_HUMAN, P62807Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodelingFunction: Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier ofthe colonic epithelium, and to the bactericidal activity of amniotic fluid Gene Wiki entry for HIST1H2BI
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Genomic Views for HIST1H2BI gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the HIST1H2BI gene promoter: NF-YA NRSF form 1 XBP-1 NRSF form 2 CBF-A CBF-B FOXO4 CP1A NF-Y CBF(2) Other transcription factors
Search SABiosciences Chromatin IP Primers for HIST1H2BI
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIST1H2BI |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p22.1 Ensembl cytogenetic band: 6p22.2 HGNC cytogenetic band: 6p22.1HIST1H2BI Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P026273: view genomic region
(about GC identifiers)
Start:
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26,273,144 bp from pter |
End:
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26,273,640 bp from pter |
Size:
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497 bases |
Orientation:
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plus strand |
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Proteins for HIST1H2BI gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: H2B1C_HUMAN, P62807 (See
protein sequence)Recommended Name: Histone H2B type 1-C/E/F/G/I Size: 126 amino acids; 13906 Da
Subunit: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in oneH3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA
Subcellular location: Nucleus. Chromosome
Secondary accessions: P02278 Q3B872 Q4VB69 Q93078 Q93080Explore the universe of human proteins at neXtProt for HIST1H2BI: NX_P62807
Post-translational modifications:
Monoubiquitination at Lys-35 (H2BK34Ub) by the MSL1/MSL2 dimer is required for histone H3 'Lys-4' (H3K4me) and 'Lys-79'(H3K79me) methylation and transcription activation at specific gene loci, such as HOXA9 and MEIS1 loci. Similarly,monoubiquitination at Lys-121 (H2BK120Ub) by the RNF20/40 complex gives a specific tag for epigenetic transcriptionalactivation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It also functions cooperativelywith the FACT dimer to stimulate elongation by RNA polymerase II1
Phosphorylation at Ser-37 (H2BS36ph) by AMPK in response to stress promotes transcription (By similarity).Phosphorylated on Ser-15 (H2BS14ph) by STK4/MST1 during apoptosis; which facilitates apoptotic chromatin condensation.Also phosphorylated on Ser-15 in response to DNA double strand breaks (DSBs), and in correlation with somatichypermutation and immunoglobulin class-switch recombination1
GlcNAcylation at Ser-113 promotes monoubiquitination of Lys-121. It fluctuates in response to extracellular glucose,and associates with transcribed genes1
Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells,including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks activepromoters and enhancers and confers resistance to transcriptional repressors. It is also associated withpost-meiotically activated genes on autosomes1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P62807 HIST1H2BI Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins: NP_003516.1 ENSEMBL proteins: ENSP00000366962 Reactome Protein details: P62807 Human Recombinant Protein Products for HIST1H2BI:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
HIST1H2BI for ontologies About GeneDecksing
HIST1H2BI Antibody Products: Assay Products for HIST1H2BI: |
Protein
Domains / Families for HIST1H2BI gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HIST1H2BI for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P62807ProtoNet protein and cluster: P62807 UniProtKB/Swiss-Prot: H2B1C_HUMAN, P62807Similarity: Belongs to the histone H2B family |
Function for HIST1H2BI gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: H2B1C_HUMAN, P62807Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodelingFunction: Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier ofthe colonic epithelium, and to the bactericidal activity of amniotic fluid Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
-- | -- |
HIST1H2BI for ontologies About GeneDecksing
Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H2BI OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H2BI OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: HIST1H2BI (NM_003525) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
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|
Pathways & Interactions for HIST1H2BI gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Meiotic Synapsis | | | 2 | RSF Complex Binds the Centromere. | | | 3 | Signal transduction Activin A signaling regulation | | | 4 | Formation of Meiotic Holliday Junction | | | 5 | Disease | |
Pathway sources See GeneCards unified pathways Show all pathways
2 EMD Millipore Pathways for HIST1H2BI
1 GeneGo (Thomson Reuters) Pathway for HIST1H2BI 5/17
Reactome Pathways for HIST1H2BI (see all 17)
1
Kegg Pathway (Kegg details for HIST1H2BI):
HIST1H2BI for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HIST1H2BI
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
 5/199 Interacting proteins for HIST1H2BI (P628072, 3 ENSP000003669624) via UniProtKB, MINT, STRING, and/or I2D (see all 199)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006334 | nucleosome assembly |
-- | -- | | GO:0042742 | defense response to bacterium |
-- | -- |
HIST1H2BI for ontologies About GeneDecksing
|
Drugs & Compounds for HIST1H2BI gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for HIST1H2BI Search CenterWatch for drugs/clinical trials and news about HIST1H2BI / H2B1C 
|
Transcripts for HIST1H2BI gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for HIST1H2BI gene: NM_003525.2 Unigene Cluster for HIST1H2BI: Histone cluster 1, H2bi Hs.553506 Unigene Representative Sequence: DA5099951 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000377733(uc003nhk.3)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H2BI OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H2BI OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: HIST1H2BI (NM_003525) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HIST1H2BI | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HIST1H2BI  |
Additional cDNA sequence: BC101653.1 BC101655.1 1 DOTS entry: DT.91646839 1 AceView cDNA sequence: NM_003525 GeneLoc Exon Structure
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Expression for HIST1H2BI gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HIST1H2BI expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CCTGAACCAG
 About this image See HIST1H2BI Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for HIST1H2BI
SOURCE GeneReport for Unigene cluster: Hs.553506 SABiosciences Custom PCR Arrays for HIST1H2BI
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HIST1H2BI Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HIST1H2BI | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST1H2BI | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST1H2BI |
Orthologs for HIST1H2BI gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for HIST1H2BI gene from 4/13 species (see all 13) About this table
ENSEMBL Gene Tree for HIST1H2BI (if available) TreeFam Gene Tree for HIST1H2BI (if available)  |
Paralogs for HIST1H2BI gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for HIST1H2BI gene
- HIST1H2BE1 2 HIST1H2BF1 2 HIST1H2BC1 2 HIST1H2BG1 2 HIST2H2BE1 2 HIST3H2BB2 HIST1H2BK2 HIST1H2BD2
- HIST2H2BF2 HIST1H2BH2 HIST1H2BL2 HIST1H2BO2 HIST1H2BJ2 HIST1H2BB2
18/20 SIMAP similar genes for HIST1H2BI using alignment to 1 protein entry: H2B1C_HUMAN(see all similar genes):HIST1H2BB HIST1H2BD HIST1H2BF HIST1H2BH HIST1H2BJ HIST1H2BK HIST1H2BM HIST1H2BN HIST1H2BO HIST2H2BE HIST2H2BF HIST3H2BB H2BFS HIST1H2BC HIST1H2BL HIST2H2BC HIST2H2BD HIST1H2BA
HIST1H2BI for paralogs About GeneDecksing
|
Genomic Variants for HIST1H2BI gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 6 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for HIST1H2BI (26273144 - 26273640 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for HIST1H2BI: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HIST1H2BI |
|
Disorders
/ Diseases for HIST1H2BI gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HIST1H2BI for disorders About GeneDecksing
OMIM gene information: 602807
OMIM disorders: --
3 diseases for HIST1H2BI: About MalaCardssystemic lupus erythematosus lupus erythematosus immunodeficiency Human Genome Epidemiology (HuGE) Navigator: HIST1H2BI (1 document) Export disorders for HIST1H2BI gene to outside databases
|
Publications for HIST1H2BI gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HIST1H2BI gene, integrated from 9 sources (see all 29): (articles sorted by number of sources associating them with HIST1H2BI) | |  | Utopia: connect your pdf to the dynamic world of online information |
- The human and mouse replication-dependent histone genes. (PubMed id 12408966)1, 2, 3 Marzluff W.F....Maltais L.J. (2002)
- Human histone gene organization: nonregular arrangement within a large cluster. (PubMed id 9119399)1, 2, 3 Albig W.... Doenecke D. (1997)
- Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. (PubMed id 16307923)1, 2 Zhu B.... Reinberg D. (2005)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- GlcNAcylation of histone H2B facilitates its monoubiquitination. (PubMed id 22121020)2 Fujiki R.... Kato S. (2011)
- Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF). (PubMed id 21907836)1 Zhao J....Yang P. (2011)
- Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. (PubMed id 21925322)2 Tan M.... Zhao Y. (2011)
- The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K7 9 methylation. (PubMed id 21726816)2 Wu L....Dou Y. (2011)
- A modified 'cross-talk' between histone H2B Lys-120 ubiquitination and H3 Lys-79 methylation. (PubMed id 20442396)1 Darwanto A....Zhang K. (2010)
- Investigation of genetic susceptibility factors for h uman longevity - A targeted nonsynonymous SNP study. (PubMed id 20800603)1 Flachsbart F....Nebel A. (2010)
|
External Searches for HIST1H2BI gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing HIST1H2BI gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HIST1H2BI gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HIST1H2BI gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for HIST1H2BI | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for HIST1H2BI gene: Search GeneIP for patents involving HIST1H2BI
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for HIST1H2BI gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HIST1H2BI | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HIST1H2BI | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIST1H2BI | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HIST1H2BI | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST1H2BI | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST1H2BI |
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 | | HIST1H2BI Proteins, Antibodies, CLIAs, and ELISAs |
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