Aliases for HIST1H2BH Gene
Aliases for HIST1H2BH Gene
External Ids for HIST1H2BH Gene
- HGNC: 4755
- Entrez Gene: 8345
- Ensembl: ENSG00000275713
- OMIM: 602806
- UniProtKB: Q93079
Previous HGNC Symbols for HIST1H2BH Gene
- H2BFJ
Previous GeneCards Identifiers for HIST1H2BH Gene
- GC06P026309
- GC06P026359
- GC06P026194
Summaries for HIST1H2BH Gene
-
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
GeneCards Summary for HIST1H2BH Gene
HIST1H2BH (Histone Cluster 1 H2B Family Member H) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST2H2BF.
UniProtKB/Swiss-Prot for HIST1H2BH Gene
-
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HIST1H2BH Gene
Genomics for HIST1H2BH Gene
Regulatory Elements for HIST1H2BH Gene
Enhancers for HIST1H2BH Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH06G026294 | 1.6 | Ensembl ENCODE dbSUPER | 11.1 | +44.8 | 44774 | 3.2 | HDGF HNRNPUL1 FOXA2 PKNOX1 CREB3L1 MLX ARNT ARID4B SIN3A DMAP1 | HMGN4 HIST1H3E HIST1H2APS4 HIST1H3G HIST1H2BH HIST1H2BD HIST1H1E HIST1H4G HIST1H2BE LARP1P1 |
| GH06G026120 | 2.1 | FANTOM5 Ensembl ENCODE dbSUPER | 1.6 | -127.7 | -127677 | 7.8 | CREB3L1 MLX ZFP64 DMAP1 YY1 SLC30A9 SP3 NFYC TBX21 SSRP1 | ABT1 ENSG00000272462 HMGN4 NUP50P2 ZNF322 HFE BTN3A2 HIST1H1C HIST1H2APS5 BTN3A1 |
| GH06G026248 | 1.6 | Ensembl ENCODE dbSUPER | 0.7 | +3.7 | 3719 | 12.9 | HDGF PKNOX1 FOXA2 ARNT CREB3L1 MLX WRNIP1 ARID4B SIN3A YY1 | ABT1 HIST1H3E HMGN4 HIST1H2APS3 HIST1H4H HIST1H2BE LARP1P1 HIST1H4C HIST1H2AE ENSG00000272462 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HIST1H2BH on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the HIST1H2BH gene promoter:
Regulatory Element Products
Genomic Location for HIST1H2BH Gene
- Chromosome:
- 6
- Start:
- 26,251,651 bp from pter
- End:
- 26,253,710 bp from pter
- Size:
- 2,060 bases
- Orientation:
- Plus strand
Genomic View for HIST1H2BH Gene
Genes around HIST1H2BH on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.2 by Ensembl
- 6p22.2 by Entrez Gene
- 6p22.2 by HGNC
HIST1H2BH Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HIST1H2BH Gene
Proteins for HIST1H2BH Gene
-
Protein details for HIST1H2BH Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q93079-H2B1H_HUMAN
- Recommended name:
- Histone H2B type 1-H
- Protein Accession:
- Q93079
- B2R541
- Q4VB74
Protein attributes for HIST1H2BH Gene
- Size:
- 126 amino acids
- Molecular mass:
- 13892 Da
- Quaternary structure:
-
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Protein Expression for HIST1H2BH Gene
Post-translational modifications for HIST1H2BH Gene
- Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells, including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. It is also associated with post-meiotically activated genes on autosomes.
- GlcNAcylation at Ser-113 promotes monoubiquitination of Lys-121. It fluctuates in response to extracellular glucose, and associates with transcribed genes (By similarity).
- Monoubiquitination at Lys-35 (H2BK34Ub) by the MSL1/MSL2 dimer is required for histone H3 Lys-4 (H3K4me) and Lys-79 (H3K79me) methylation and transcription activation at specific gene loci, such as HOXA9 and MEIS1 loci. Similarly, monoubiquitination at Lys-121 (H2BK120Ub) by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 Lys-4 and Lys-79 methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II. H2BK120Ub also acts as a regulator of mRNA splicing: deubiquitination by USP49 is required for efficient cotranscriptional splicing of a large set of exons.
- Phosphorylation at Ser-37 (H2BS36ph) by AMPK in response to stress promotes transcription (By similarity). Phosphorylated on Ser-15 (H2BS14ph) by STK4/MST1 during apoptosis; which facilitates apoptotic chromatin condensation. Also phosphorylated on Ser-15 in response to DNA double strand breaks (DSBs), and in correlation with somatic hypermutation and immunoglobulin class-switch recombination.
- Ubiquitination at isoforms=121
- Glycosylation at posLast=113113
- Modification sites at PhosphoSitePlus
Other Protein References for HIST1H2BH Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Invitrogen Antibodies for HIST1H2BH
- antibodies-online Antibodies for HIST1H2BH: See all 3
- Search GeneTex for Antibodies for HIST1H2BH
Protein Products
-
OriGene Purified Proteins for HIST1H2BH
- Search Origene for MassSpec and Protein Over-expression Lysates for HIST1H2BH
- Origene Custom Protein Services for HIST1H2BH
- Novus Biologicals lysates for HIST1H2BH
- Search GeneTex for Proteins for HIST1H2BH
Assay Products
No data available for DME Specific Peptides for HIST1H2BH Gene
Domains & Families for HIST1H2BH Gene
Gene Families for HIST1H2BH Gene
- HGNC:
Protein Domains for HIST1H2BH Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for HIST1H2BH Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q93079- Family:
-
- Belongs to the histone H2B family.
Function for HIST1H2BH Gene
Molecular function for HIST1H2BH Gene
- UniProtKB/Swiss-Prot Function:
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | NAS | 9119399 |
| GO:0046982 | protein heterodimerization activity | IEA | -- |
Phenotypes for HIST1H2BH Gene
- GenomeRNAi human phenotypes for HIST1H2BH:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for HIST1H2BH gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HIST1H2BH gene
- Search ViGene Biosciences for HIST1H2BH
CRISPR Products
-
OriGene CRISPR knockouts for HIST1H2BH
-
Santa Cruz Biotechnology (SCBT) CRISPR for HIST1H2BH
- GenScript: Design CRISPR guide RNA sequences for HIST1H2BH
miRNA for HIST1H2BH Gene
- miRTarBase miRNAs that target HIST1H2BH
-
- hsa-mir-98-5p (MIRT027544)
- hsa-mir-652-3p (MIRT039495)
- hsa-mir-320a (MIRT044418)
- hsa-mir-146a-3p (MIRT360292)
- hsa-mir-760 (MIRT360293)
- hsa-mir-1276 (MIRT360294)
- hsa-mir-3940-5p (MIRT360298)
- hsa-mir-4507 (MIRT360299)
- hsa-mir-6839-3p (MIRT360301)
- hsa-mir-8057 (MIRT360302)
- hsa-mir-5693 (MIRT511707)
- hsa-mir-6822-3p (MIRT511708)
- hsa-mir-629-5p (MIRT511709)
- hsa-mir-4766-5p (MIRT511710)
miRNA Products
- Search ViGene Biosciences for HIST1H2BH
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HIST1H2BH
- Browse OriGene Inhibitory RNA Products For HIST1H2BH
-
ViGene Biosciences ready-to-package AAV shRNAs for HIST1H2BH gene
Clone Products
-
OriGene ORF clones in human for HIST1H2BH
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for HIST1H2BH
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for HIST1H2BH
-
ViGene Biosciences adenoviral particle packaged cDNA for HIST1H2BH gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HIST1H2BH gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HIST1H2BH gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HIST1H2BH Gene
Localization for HIST1H2BH Gene
Subcellular locations from UniProtKB/Swiss-Prot for HIST1H2BH Gene
- Nucleus. Chromosome.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
| cytosol | 4 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000786 | nucleosome | NAS | 9119399 |
| GO:0005634 | nucleus | IEA,IDA | 16319397 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005694 | chromosome | IEA | -- |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for HIST1H2BH Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 |
.88
|
.34
|
| 2 | DNA Double-Strand Break Repair |
.53
|
|
| 3 | Cellular Senescence | ||
| 4 | Chromosome Maintenance | ||
| 5 | Cell Cycle, Mitotic |
.83
|
.60
|
Pathways by source for HIST1H2BH Gene
1 BioSystems pathway for HIST1H2BH Gene
68 Reactome pathways for HIST1H2BH Gene
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Activation of HOX genes during differentiation
- Amyloid fiber formation
- B-WICH complex positively regulates rRNA expression
3 KEGG pathways for HIST1H2BH Gene
1 GeneGo (Thomson Reuters) pathway for HIST1H2BH Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006334 | nucleosome assembly | NAS | 9119399 |
| GO:0016567 | protein ubiquitination | TAS | -- |
No data available for SIGNOR curated interactions for HIST1H2BH Gene
Transcripts for HIST1H2BH Gene
mRNA/cDNA for HIST1H2BH Gene
- (1) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (6) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HIST1H2BH Gene
CRISPR Products
-
OriGene CRISPR knockouts for HIST1H2BH
-
Santa Cruz Biotechnology (SCBT) CRISPR for HIST1H2BH
- GenScript: Design CRISPR guide RNA sequences for HIST1H2BH
miRNA Products
- Search ViGene Biosciences for HIST1H2BH
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HIST1H2BH
- Browse OriGene Inhibitory RNA Products For HIST1H2BH
-
ViGene Biosciences ready-to-package AAV shRNAs for HIST1H2BH gene
Clone Products
-
OriGene ORF clones in human for HIST1H2BH
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for HIST1H2BH
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for HIST1H2BH Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Kidney (Urinary System)
- Presumptive Podocytes Podocyte Layer
-
Epithelial Cells
- Presumptive Podocytes Podocyte Layer
- NULL (Uncategorized)
-
Prostate (Endocrine System)
mRNA differential expression in normal tissues according to GTEx for HIST1H2BH Gene
This gene is overexpressed in Whole Blood (x6.5) and Esophagus - Mucosa (x5.2).
This gene is overexpressed in Saliva (57.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for HIST1H2BH Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of HIST1H2BH Gene:
HIST1H2BHSOURCE GeneReport for Unigene cluster for HIST1H2BH Gene:
Hs.247815Evidence on tissue expression from TISSUES for HIST1H2BH Gene
- Nervous system(4.3)
Primer Products
-
OriGene qPCR primer pairs for HIST1H2BH
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HIST1H2BH Gene
Orthologs for HIST1H2BH Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LOC463172 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Hist1h2bq 34 |
|
||
| Hist1h2br 16 |
|
|
|||
| dog (Canis familiaris) |
Mammalia | LOC483164 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | LOC100359692 34 |
|
||
| cow (Bos Taurus) |
Mammalia | HIST2H2BF 34 |
|
||
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AGR183C 34 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | HTB2 34 |
|
||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0F13310g 34 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT3G53650 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os01g0153100 34 |
|
||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU02435 34 |
|
||
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | htb1 34 |
|
- Species where no ortholog for HIST1H2BH was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for HIST1H2BH Gene
(23) SIMAP similar genes for HIST1H2BH Gene using alignment to 1 proteins:
Variants for HIST1H2BH Gene
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000465845 | -- | 26,249,769(+) | TTCAA(C/T)GGCTG | downstream-variant-500B, upstream-variant-2KB | |
| rs1000601191 | -- | 26,249,935(+) | TTTGT(A/G)TAAGT | downstream-variant-500B, upstream-variant-2KB | |
| rs1001532143 | -- | 26,250,701(+) | CTTCC(A/T)GTTTC | upstream-variant-2KB | |
| rs1001720064 | -- | 26,252,297(+) | TCCCA(C/T)CTCGG | downstream-variant-500B, upstream-variant-2KB | |
| rs1005553179 | -- | 26,252,320(+) | TTACT(A/G)AGCAG | downstream-variant-500B, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv5926n100 | CNV | gain | 25217958 |
| nsv1023453 | CNV | gain | 25217958 |
| nsv428137 | CNV | loss | 18775914 |
| nsv601173 | CNV | loss | 21841781 |
| nsv981112 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
25.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.30;
6.69% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HIST1H2BH Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HIST1H2BH
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HIST1H2BH Gene
Disorders for HIST1H2BH Gene
Relevant External Links for HIST1H2BH
No disorders were found for HIST1H2BH Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HIST1H2BH Gene
Publications for HIST1H2BH Gene
- The human and mouse replication-dependent histone genes. (PMID: 12408966) Marzluff W.F. … Maltais L.J. (Genomics 2002) 2 3 4 64
- Human histone gene organization: nonregular arrangement within a large cluster. (PMID: 9119399) Albig W. … Doenecke D. (Genomics 1997) 2 3 4 64
- Gene-specific characterization of human histone H2B by electron capture dissociation. (PMID: 16457587) Siuti N. … Pesavento J.J. (J. Proteome Res. 2006) 3 4 64
- Quantitative proteomic analysis of post-translational modifications of human histones. (PMID: 16627869) Beck H.C. … Jensen O.N. (Mol. Cell. Proteomics 2006) 3 4 64
- Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. (PMID: 16713563) Pavri R. … Reinberg D. (Cell 2006) 3 4 64
Products for HIST1H2BH Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for HIST1H2BH
- Search Origene for MassSpec and Protein Over-expression Lysates for HIST1H2BH
- Origene Custom Protein Services for HIST1H2BH
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HIST1H2BH
- Browse OriGene Inhibitory RNA Products For HIST1H2BH
- OriGene qPCR primer pairs for HIST1H2BH
- OriGene CRISPR knockouts for HIST1H2BH
- OriGene ORF clones in human for HIST1H2BH
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HIST1H2BH
- GenScript: Next-day shipping cDNA ORF clone for HIST1H2BH in any vector
- GenScript Custom Purified and Recombinant Proteins Services for HIST1H2BH
- GenScript Custom Assay Services for HIST1H2BH
- GenScript Custom overexpressing Cell Line Services for HIST1H2BH
- GenScript: Design CRISPR guide RNA sequences for HIST1H2BH
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for HIST1H2BH
- Sino Biological Human cDNA Clone for HIST1H2BH
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals lysates for HIST1H2BH
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Invitrogen Antibodies for HIST1H2BH
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ViGene Biosciences adenoviral particle packaged cDNA for HIST1H2BH gene
- ViGene Biosciences lentiviral particle packaged cDNA for HIST1H2BH gene
- ViGene Biosciences ready-to-package AAV shRNAs for HIST1H2BH gene
- Search ViGene Biosciences for HIST1H2BH
- Search Santa Cruz Biotechnology (SCBT) for HIST1H2BH Antibodies
- Search Santa Cruz Biotechnology (SCBT) for HIST1H2BH siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HIST1H2BH
- Horizon Cell Lines for HIST1H2BH
- Cyagen custom Knockout/knockin (KOKI) mouse models for HIST1H2BH
- VectorBuilder custom plasmid, inducible vectors for HIST1H2BH
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HIST1H2BH
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HIST1H2BH Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer