Aliases for HIST1H2BG Gene
Aliases for HIST1H2BG Gene
- Histone Cluster 1 H2B Family Member G 2 3 5
- H2B Histone Family, Member A 2 3
- Histone Cluster 1, H2bg 2 3
- Histone H2B.1 A 3 4
- Histone 1, H2bg 2 3
- Histone H2B.A 3 4
- H2B/A 3 4
- H2BFA 3 4
- HIST1H2BC HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BI 4
- Histone H2B Type 1-C/E/F/G/I 3
- Histone H2B.G 4
- Histone H2B.H 4
- Histone H2B.K 4
External Ids for HIST1H2BG Gene
- HGNC: 4746
- Entrez Gene: 8339
- Ensembl: ENSG00000273802
- OMIM: 602798
- UniProtKB: P62807
Previous HGNC Symbols for HIST1H2BG Gene
- H2BFA
Previous GeneCards Identifiers for HIST1H2BG Gene
- GC06M026273
- GC06M026324
- GC06M026216
- GC06M026159
- GC06M026230
- GC06M026232
- GC06M026252
Summaries for HIST1H2BG Gene
-
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein has antibacterial and antifungal antimicrobial activity. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
GeneCards Summary for HIST1H2BG Gene
HIST1H2BG (Histone Cluster 1 H2B Family Member G) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BE.
UniProtKB/Swiss-Prot for HIST1H2BG Gene
-
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
-
Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HIST1H2BG Gene
Genomics for HIST1H2BG Gene
Regulatory Elements for HIST1H2BG Gene
Regulatory Element Products
Genomic Location for HIST1H2BG Gene
- Chromosome:
- 6
- Start:
- 26,215,159 bp from pter
- End:
- 26,216,692 bp from pter
- Size:
- 1,534 bases
- Orientation:
- Minus strand
Genomic View for HIST1H2BG Gene
Genes around HIST1H2BG on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.2 by Ensembl
- 6p22.2 by Entrez Gene
- 6p22.2 by HGNC
HIST1H2BG Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HIST1H2BG Gene
Proteins for HIST1H2BG Gene
-
Protein details for HIST1H2BG Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P62807-H2B1C_HUMAN
- Recommended name:
- Histone H2B type 1-C/E/F/G/I
- Protein Accession:
- P62807
- P02278
- Q3B872
- Q4VB69
- Q93078
- Q93080
Protein attributes for HIST1H2BG Gene
- Size:
- 126 amino acids
- Molecular mass:
- 13906 Da
- Quaternary structure:
-
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
- The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Protein Expression for HIST1H2BG Gene
Post-translational modifications for HIST1H2BG Gene
- Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells, including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. It is also associated with post-meiotically activated genes on autosomes.
- GlcNAcylation at Ser-113 promotes monoubiquitination of Lys-121. It fluctuates in response to extracellular glucose, and associates with transcribed genes.
- Monoubiquitination at Lys-35 (H2BK34Ub) by the MSL1/MSL2 dimer is required for histone H3 Lys-4 (H3K4me) and Lys-79 (H3K79me) methylation and transcription activation at specific gene loci, such as HOXA9 and MEIS1 loci. Similarly, monoubiquitination at Lys-121 (H2BK120Ub) by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 Lys-4 and Lys-79 methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II. H2BK120Ub also acts as a regulator of mRNA splicing: deubiquitination by USP49 is required for efficient cotranscriptional splicing of a large set of exons.
- Phosphorylation at Ser-37 (H2BS36ph) by AMPK in response to stress promotes transcription (By similarity). Phosphorylated on Ser-15 (H2BS14ph) by STK4/MST1 during apoptosis; which facilitates apoptotic chromatin condensation. Also phosphorylated on Ser-15 in response to DNA double strand breaks (DSBs), and in correlation with somatic hypermutation and immunoglobulin class-switch recombination.
- Ubiquitination at isoforms=121
- Glycosylation at isoforms=113
- Modification sites at PhosphoSitePlus
Other Protein References for HIST1H2BG Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore top HIST1H2BG Antibody
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for HIST1H2BG
- Search GeneTex for Antibodies for HIST1H2BG
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HIST1H2BG
- Origene Custom Protein Services for HIST1H2BG
- Search GeneTex for Proteins for HIST1H2BG
Assay Products
No data available for DME Specific Peptides for HIST1H2BG Gene
Domains & Families for HIST1H2BG Gene
Gene Families for HIST1H2BG Gene
- HGNC:
Protein Domains for HIST1H2BG Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for HIST1H2BG Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P62807- Family:
-
- Belongs to the histone H2B family.
Function for HIST1H2BG Gene
Molecular function for HIST1H2BG Gene
- UniProtKB/Swiss-Prot Function:
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
- UniProtKB/Swiss-Prot Function:
- Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | NAS,IBA | 422550 |
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0046982 | protein heterodimerization activity | IEA | -- |
Phenotypes for HIST1H2BG Gene
- GenomeRNAi human phenotypes for HIST1H2BG:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for HIST1H2BG gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HIST1H2BG gene
- Search ViGene Biosciences for HIST1H2BG
CRISPR Products
-
OriGene CRISPR knockouts for HIST1H2BG
-
Santa Cruz Biotechnology (SCBT) CRISPR for HIST1H2BG
- GenScript: Design CRISPR guide RNA sequences for HIST1H2BG
miRNA for HIST1H2BG Gene
- miRTarBase miRNAs that target HIST1H2BG
-
- hsa-mir-98-5p (MIRT027529)
- hsa-mir-615-3p (MIRT040271)
- hsa-mir-760 (MIRT396023)
- hsa-mir-6822-3p (MIRT396024)
- hsa-mir-5693 (MIRT450572)
- hsa-mir-6790-5p (MIRT450573)
- hsa-mir-4658 (MIRT450574)
- hsa-mir-4758-5p (MIRT450575)
- hsa-mir-1238-5p (MIRT450576)
- hsa-mir-3672 (MIRT450577)
- hsa-mir-6864-3p (MIRT450578)
- hsa-mir-4745-5p (MIRT450579)
- hsa-mir-4481 (MIRT450580)
- hsa-mir-4501 (MIRT450581)
- hsa-mir-873-3p (MIRT450582)
- hsa-mir-6796-3p (MIRT450583)
- hsa-mir-8081 (MIRT511711)
- hsa-mir-8057 (MIRT511712)
- hsa-mir-9-3p (MIRT511713)
- hsa-mir-4766-5p (MIRT511714)
- hsa-mir-146a-3p (MIRT511715)
- hsa-mir-1276 (MIRT511716)
- hsa-mir-7151-3p (MIRT626910)
- hsa-mir-5095 (MIRT626911)
- hsa-mir-150-5p (MIRT626912)
- hsa-mir-186-3p (MIRT626913)
- hsa-mir-520h (MIRT626914)
- hsa-mir-520g-3p (MIRT626915)
- hsa-mir-6504-3p (MIRT626916)
- hsa-mir-3159 (MIRT626917)
- hsa-mir-520e (MIRT626918)
- hsa-mir-520d-3p (MIRT626919)
- hsa-mir-520c-3p (MIRT626920)
- hsa-mir-520b (MIRT626921)
- hsa-mir-520a-3p (MIRT626922)
- hsa-mir-373-3p (MIRT626923)
- hsa-mir-372-3p (MIRT626924)
- hsa-mir-302e (MIRT626925)
- hsa-mir-302d-3p (MIRT626926)
- hsa-mir-302c-3p (MIRT626927)
- hsa-mir-302b-3p (MIRT626928)
- hsa-mir-302a-3p (MIRT626929)
- hsa-mir-93-5p (MIRT626930)
- hsa-mir-526b-3p (MIRT626931)
- hsa-mir-519d-3p (MIRT626932)
- hsa-mir-20b-5p (MIRT626933)
- hsa-mir-20a-5p (MIRT626934)
- hsa-mir-17-5p (MIRT626935)
- hsa-mir-106b-5p (MIRT626936)
- hsa-mir-106a-5p (MIRT626937)
miRNA Products
- Search ViGene Biosciences for HIST1H2BG
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HIST1H2BG
- Browse OriGene Inhibitory RNA Products For HIST1H2BG
-
ViGene Biosciences ready-to-package AAV shRNAs for HIST1H2BG gene
Clone Products
-
OriGene ORF clones in human for HIST1H2BG
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
Cell Line Products
-
Horizon Cell Lines for HIST1H2BG
-
ViGene Biosciences adenoviral particle packaged cDNA for HIST1H2BG gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HIST1H2BG gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HIST1H2BG gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HIST1H2BG Gene
Localization for HIST1H2BG Gene
Subcellular locations from UniProtKB/Swiss-Prot for HIST1H2BG Gene
- Nucleus. Chromosome.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
| cytosol | 4 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000786 | nucleosome | NAS | 422550 |
| GO:0005615 | extracellular space | IDA | 12860195 |
| GO:0005634 | nucleus | IDA | 21630459 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005694 | chromosome | IEA | -- |
Pathways & Interactions for HIST1H2BG Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 |
.88
|
.34
|
| 2 | DNA Double-Strand Break Repair |
.53
|
|
| 3 | Cellular Senescence | ||
| 4 | Chromosome Maintenance | ||
| 5 | Cell Cycle, Mitotic |
.83
|
.60
|
Pathways by source for HIST1H2BG Gene
68 Reactome pathways for HIST1H2BG Gene
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Activation of HOX genes during differentiation
- Amyloid fiber formation
- B-WICH complex positively regulates rRNA expression
3 KEGG pathways for HIST1H2BG Gene
1 GeneGo (Thomson Reuters) pathway for HIST1H2BG Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002227 | innate immune response in mucosa | IDA | 12860195 |
| GO:0006334 | nucleosome assembly | NAS | 422550 |
| GO:0016567 | protein ubiquitination | TAS | -- |
| GO:0019731 | antibacterial humoral response | IDA | 12860195 |
| GO:0042742 | defense response to bacterium | IEA | -- |
No data available for SIGNOR curated interactions for HIST1H2BG Gene
Transcripts for HIST1H2BG Gene
mRNA/cDNA for HIST1H2BG Gene
- (1) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (38) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HIST1H2BG Gene
CRISPR Products
-
OriGene CRISPR knockouts for HIST1H2BG
-
Santa Cruz Biotechnology (SCBT) CRISPR for HIST1H2BG
- GenScript: Design CRISPR guide RNA sequences for HIST1H2BG
miRNA Products
- Search ViGene Biosciences for HIST1H2BG
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HIST1H2BG
- Browse OriGene Inhibitory RNA Products For HIST1H2BG
-
ViGene Biosciences ready-to-package AAV shRNAs for HIST1H2BG gene
Clone Products
-
OriGene ORF clones in human for HIST1H2BG
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
Flow Cytometry Products
Expression for HIST1H2BG Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Kidney (Urinary System)
- Presumptive Podocytes Podocyte Layer
-
Epithelial Cells
- Presumptive Podocytes Podocyte Layer
-
Thymus (Hematopoietic System)
- Double Positive Thymocytes Thymus
-
Blood (Cardiovascular System)
- Double Positive Thymocytes Thymus
-
Heart (Cardiovascular System)
- Cardiac Fibroblasts Myocardium
-
Fibroblasts
- Cardiac Fibroblasts Myocardium
-
Ovary (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for HIST1H2BG Gene
This gene is overexpressed in Cervix - Ectocervix (x7.4), Whole Blood (x5.2), and Vagina (x4.5).
This gene is overexpressed in Tlymphocyte (13.3), Ovary (12.8), Monocytes (11.3), Blymphocyte (6.7), Liver, secretome (6.5), and Neutrophil (6.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for HIST1H2BG Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of HIST1H2BG Gene:
HIST1H2BGSOURCE GeneReport for Unigene cluster for HIST1H2BG Gene:
Hs.591809Evidence on tissue expression from TISSUES for HIST1H2BG Gene
- Lung(4.3)
- Spleen(4.3)
Primer Products
-
OriGene qPCR primer pairs for HIST1H2BG
-
OriGene qPCR primer pairs and template standards for HIST1H2BG
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HIST1H2BG Gene
Orthologs for HIST1H2BG Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LOC100610052 34 |
|
||
| dog (Canis familiaris) |
Mammalia | LOC611482 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Hist1h2bf 34 16 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Hist1h2bf 34 |
|
||
| cow (Bos Taurus) |
Mammalia | LOC787465 34 |
|
||
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AEL002W 34 |
|
- Species where no ortholog for HIST1H2BG was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for HIST1H2BG Gene
Paralogs for HIST1H2BG Gene
(23) SIMAP similar genes for HIST1H2BG Gene using alignment to 2 proteins:
Variants for HIST1H2BG Gene
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1002538521 | -- | 26,216,563(+) | TTCTT(A/G)CCATC | upstream-variant-2KB, reference, synonymous-codon | |
| rs1002793227 | -- | 26,217,725(+) | GTTTA(C/T)TCATG | downstream-variant-500B, upstream-variant-2KB | |
| rs1002799030 | -- | 26,216,322(+) | CTTGG(A/C)CAGCT | upstream-variant-2KB, reference, missense | |
| rs1002951859 | -- | 26,218,119(+) | AAGAC(G/T)ACGTC | upstream-variant-2KB | |
| rs1006613157 | -- | 26,218,200(+) | AAAAG(C/G)AGCAA | upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv5926n100 | CNV | gain | 25217958 |
| nsv1021294 | CNV | loss | 25217958 |
| nsv1023453 | CNV | gain | 25217958 |
| nsv428137 | CNV | loss | 18775914 |
Residual Variation Intolerance Score:
42.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.63;
13.57% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HIST1H2BG Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HIST1H2BG
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HIST1H2BG Gene
Disorders for HIST1H2BG Gene
Relevant External Links for HIST1H2BG
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- HIST1H2BG
No disorders were found for HIST1H2BG Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HIST1H2BG Gene
Publications for HIST1H2BG Gene
- The human and mouse replication-dependent histone genes. (PMID: 12408966) Marzluff W.F. … Maltais L.J. (Genomics 2002) 2 3 4 64
- Isolation and characterization of two human H1 histone genes within clusters of core histone genes. (PMID: 1916825) Albig W. … Doenecke D. (Genomics 1991) 2 3 4 64
- Gene-specific characterization of human histone H2B by electron capture dissociation. (PMID: 16457587) Siuti N. … Pesavento J.J. (J. Proteome Res. 2006) 3 4 64
- Quantitative proteomic analysis of post-translational modifications of human histones. (PMID: 16627869) Beck H.C. … Jensen O.N. (Mol. Cell. Proteomics 2006) 3 4 64
- Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. (PMID: 16713563) Pavri R. … Reinberg D. (Cell 2006) 3 4 64
Products for HIST1H2BG Gene
- Browse Small Molecules at EMD Millipore
- EMD Millipore top HIST1H2BG Antibody
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for HIST1H2BG
- Browse Purified and Recombinant Proteins at EMD Millipore
- Browse Kits and Assays available from EMD Millipore
- EMD Millipore genomic analysis products
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HIST1H2BG
- Origene Custom Protein Services for HIST1H2BG
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HIST1H2BG
- Browse OriGene Inhibitory RNA Products For HIST1H2BG
- OriGene qPCR primer pairs and template standards for HIST1H2BG
- OriGene qPCR primer pairs for HIST1H2BG
- OriGene CRISPR knockouts for HIST1H2BG
- OriGene ORF clones in human for HIST1H2BG
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HIST1H2BG
- GenScript: Next-day shipping cDNA ORF clone for HIST1H2BG in any vector
- GenScript Custom Purified and Recombinant Proteins Services for HIST1H2BG
- GenScript Custom Assay Services for HIST1H2BG
- GenScript Custom overexpressing Cell Line Services for HIST1H2BG
- GenScript: Design CRISPR guide RNA sequences for HIST1H2BG
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for HIST1H2BG
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for HIST1H2BG gene
- ViGene Biosciences lentiviral particle packaged cDNA for HIST1H2BG gene
- ViGene Biosciences ready-to-package AAV shRNAs for HIST1H2BG gene
- Search ViGene Biosciences for HIST1H2BG
- Search Santa Cruz Biotechnology (SCBT) for HIST1H2BG Antibodies
- Search Santa Cruz Biotechnology (SCBT) for HIST1H2BG siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HIST1H2BG
- Horizon Cell Lines for HIST1H2BG
- Cyagen custom Knockout/knockin (KOKI) mouse models for HIST1H2BG
- VectorBuilder custom plasmid, inducible vectors for HIST1H2BG
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HIST1H2BG
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HIST1H2BG Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer