HIST1H2AM Gene
protein-coding GIFtS: 51
GCID: GC06M027896
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histone cluster 1, H2am(Previous names: H2A histone family, member N, histone 1, H2am ) (Previous symbol: H2AFN)
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Aliases for HIST1H2AM gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Histone Cluster 1, H2am1 2 | | Histone H2A Type 12 | | H2AFN1 2 3 5 | | H2AFC3 | | H2A.11 2 3 | | H2AFD3 | | H2A/N1 | | H2AFI3 | | H2A Histone Family, Member N1 2 | | H2AFP3 | | Histone 1, H2am1 2 | | Histone H2A/P3 | | DJ193B12.11 | | |
Export aliases for HIST1H2AM gene to outside databasesPrevious GC identifers: GC06M027919 GC06M027968 GC06M027867 GC06M027668 GC06M027869 GC06M027880 |
Summaries for HIST1H2AM gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for HIST1H2AM: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber ineukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around whichapproximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts withlinker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene isintronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but insteadcontain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome6p22-p21.3. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: H2A1_HUMAN, P0C0S8Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodeling Gene Wiki entry for HIST1H2AM
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Genomic Views for HIST1H2AM gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the HIST1H2AM gene promoter: TBP Max1 Pax-5 AML1a Lmo2 CUTL1 Evi-1 FOXO4 HOXA5 ZID Other transcription factors
Search SABiosciences Chromatin IP Primers for HIST1H2AM
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIST1H2AM |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p22.1 Ensembl cytogenetic band: 6p22.1 HGNC cytogenetic band: 6p22.1HIST1H2AM Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M027896: view genomic region
(about GC identifiers)
Start:
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27,860,477 bp from pter |
End:
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27,860,963 bp from pter |
Size:
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487 bases |
Orientation:
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minus strand |
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Proteins for HIST1H2AM gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: H2A1_HUMAN, P0C0S8 (See
protein sequence)Recommended Name: Histone H2A type 1 Size: 130 amino acids; 14091 Da
Subunit: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in oneH3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA
Subcellular location: Nucleus. Chromosome
Mass spectrometry: Mass=13993.9; Method=Electrospray; Range=2-130; Note=Monoisotopic with N-acetylserine;Source=PubMed:16457589;
Secondary accessions: P02261 Q2M1R2 Q76PA6Explore the universe of human proteins at neXtProt for HIST1H2AM: NX_P0C0S8
Post-translational modifications:
The chromatin-associated form is phosphorylated on Thr-121 during mitosis (Probable)1
Deiminated on Arg-4 in granulocytes upon calcium entry1
Monoubiquitination of Lys-120 (H2AK119Ub) by RING1 and RNF2/RING2 complex gives a specific tag for epigenetictranscriptional repression and participates in X chromosome inactivation of female mammals. It is involved in theinitiation of both imprinted and random X inactivation. Ubiquitinated H2A is enriched in inactive X chromosomechromatin. Ubiquitination of H2A functions downstream of methylation of 'Lys-27' of histone H3 (H3K27me). H2AK119Ub byRNF2/RING2 can also be induced by ultraviolet and may be involved in DNA repair. Following DNA double-strand breaks(DSBs), it is ubiquitinated through 'Lys-63' linkage of ubiquitin moieties by the E2 ligase UBE2N and the E3 ligasesRNF8 and RNF168, leading to the recruitment of repair proteins to sites of DNA damage. Ubiquitination at Lys-14 andLys-16 (H2AK13Ub and H2AK15Ub, respectively) in response to DNA damage is initiated by RNF168 that mediatesmonoubiquitination at these 2 sites, and 'Lys-63'-linked ubiquitin are then conjugated to monoubiquitin; RNF8 is ableto extend 'Lys-63'-linked ubiquitin chains in vitro. H2AK119Ub and ionizing radiation-induced 'Lys-63'-linkedubiquitination (H2AK13Ub and H2AK15Ub) are distinct events1
Phosphorylation on Ser-2 is enhanced during mitosis. Phosphorylation on Ser-2 by RPS6KA5/MSK1 directly repressestranscription. Acetylation of H3 inhibits Ser-2 phosphorylation by RPS6KA5/MSK11
Symmetric dimethylation on Arg-4 by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (Bysimilarity)1
Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells,including X-linked genes that escape sex chromosome inactivation in haploid cells. Crotonylation marks activepromoters and enhancers and confers resistance to transcriptional repressors. It is also associated withpost-meiotically activated genes on autosomes1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P0C0S8 HIST1H2AM Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins: NP_003505.1 ENSEMBL proteins: ENSP00000352627 Human Recombinant Protein Products for HIST1H2AM:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
HIST1H2AM for ontologies About GeneDecksing
HIST1H2AM Antibody Products: Assay Products for HIST1H2AM: |
Protein
Domains / Families for HIST1H2AM gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HIST1H2AM for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P0C0S8ProtoNet protein and cluster: P0C0S8 1 Blocks protein family: IPB002119 Histone H2A
UniProtKB/Swiss-Prot: H2A1_HUMAN, P0C0S8Similarity: Belongs to the histone H2A family |
Function for HIST1H2AM gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: H2A1_HUMAN, P0C0S8Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodeling Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
HIST1H2AM for ontologies About GeneDecksing
Phenotypes: 1 GenomeRNAi human phenotype for HIST1H2AM: Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H2AM OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H2AM (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: HIST1H2AM (NM_003514) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HIST1H2AM | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HIST1H2AM  |
|
Pathways & Interactions for HIST1H2AM gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signal transduction Activin A signaling regulation | | | 2 | Systemic lupus erythematosus | |
Pathway sources See GeneCards unified pathways Show all pathways
2 EMD Millipore Pathways for HIST1H2AM
1 GeneGo (Thomson Reuters) Pathway for HIST1H2AM
1
Kegg Pathway (Kegg details for HIST1H2AM):
HIST1H2AM for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HIST1H2AM
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
 5/86 Interacting proteins for HIST1H2AM (P0C0S82, 3 ENSP000003526274) via UniProtKB, MINT, STRING, and/or I2D (see all 86)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006334 | nucleosome assembly |
-- | -- |
HIST1H2AM for ontologies About GeneDecksing
|
Drugs & Compounds for HIST1H2AM gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for HIST1H2AM Search CenterWatch for drugs/clinical trials and news about HIST1H2AM / H2A1 
|
Transcripts for HIST1H2AM gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for HIST1H2AM gene: NM_003514.2 Unigene Cluster for HIST1H2AM: Histone cluster 1, H2am Hs.134999 [show with all ESTs]Unigene Representative Sequence: FY2138751 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000359611(uc003nkb.1)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H2AM OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HIST1H2AM (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: HIST1H2AM (NM_003514) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HIST1H2AM | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HIST1H2AM  |
Additional cDNA sequence: AK312224.1 BC032686.1 2 DOTS entries: DT.65287282 DT.121339722 12 AceView cDNA sequences: BE253911 BC071668 BG109927 NM_003514 BX280415 BE256314 BM471951 AI138475 AI095013 BC032686 BC032756 BF478293 GeneLoc Exon Structure
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Expression for HIST1H2AM gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HIST1H2AM expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TCTGGACGTG
 About this image See HIST1H2AM Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for HIST1H2AM
SOURCE GeneReport for Unigene cluster: Hs.134999 SABiosciences Custom PCR Arrays for HIST1H2AM
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HIST1H2AM Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HIST1H2AM | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST1H2AM | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST1H2AM |
Orthologs for HIST1H2AM gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for HIST1H2AM gene from 5/20 species (see all 20) About this table
ENSEMBL Gene Tree for HIST1H2AM (if available) TreeFam Gene Tree for HIST1H2AM (if available)  |
Paralogs for HIST1H2AM gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for HIST1H2AM gene
- HIST1H2AK1 2 HIST1H2AL1 2 HIST1H2AG1 2 HIST1H2AI1 2 HIST3H2A2 HIST1H2AD2 HIST2H2AA32 HIST2H2AB2
- H2AFX2 HIST1H2AC2 HIST1H2AH2 HIST1H2AJ2 HIST2H2AA42 HIST1H2AE2 HIST2H2AC2 HIST1H2AB2
- H2AFJ2
18/23 SIMAP similar genes for HIST1H2AM using alignment to 1 protein entry: H2A1_HUMAN(see all similar genes):HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AH HIST1H2AJ HIST1H2AK HIST2H2AA3 HIST2H2AA4 HIST3H2A H2AFJ HIST1H2AA HIST2H2AB HIST2H2AC H2AFX HIST1H2APS4 H2AFZ H2AFB2
HIST1H2AM for paralogs About GeneDecksing
|
Genomic Variants for HIST1H2AM gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 6 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for HIST1H2AM (27860477 - 27860963 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for HIST1H2AM: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HIST1H2AM |
|
Disorders
/ Diseases for HIST1H2AM gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HIST1H2AM for disorders About GeneDecksing
OMIM gene information: 602796
OMIM disorders: --
4 diseases for HIST1H2AM: About MalaCardsriddle syndrome systemic lupus erythematosus lupus erythematosus immunodeficiency Export disorders for HIST1H2AM gene to outside databases
|
Publications for HIST1H2AM gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HIST1H2AM gene, integrated from 9 sources (see all 34): (articles sorted by number of sources associating them with HIST1H2AM) | |  | Utopia: connect your pdf to the dynamic world of online information |
- The human and mouse replication-dependent histone genes. (PubMed id 12408966)1, 2, 3 Marzluff W.F....Maltais L.J. (2002)
- The human histone gene cluster at the D6S105 locus. (PubMed id 9439656)1, 2, 3 Albig W. and Doenecke D. (1997)
- A novel divergently transcribed human histone H2A/H2B gene pair. (PubMed id 1768865)1, 2, 3 Dobner T.... Lipp M. (1991)
- Characterization of histones H2A and H2B variants and their post- translational modifications by mass spectrometry. (PubMed id 16319397)1, 2 Bonenfant D.... van Oostrum J. (2006)
- DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A. (PubMed id 16702407)1, 2 Bergink S.... Dantuma N.P. (2006)
- Precise characterization of human histones in the H2A gene family by top down mass spectrometry. (PubMed id 16457589)1, 2 Boyne M.T. II... Kelleher N.L. (2006)
- Deimination of histone H2A and H4 at arginine 3 in HL-60 granulocytes. (PubMed id 15823041)1, 2 Hagiwara T.... Yamada M. (2005)
- Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. (PubMed id 16359901)1, 2 Cao R.... Zhang Y. (2005)
- Role of histone H2A ubiquitination in Polycomb silencing. (PubMed id 15386022)1, 2 Wang H.... Zhang Y. (2004)
- Phosphorylation of histone H2A inhibits transcription on chromatin templates. (PubMed id 15010469)1, 2 Zhang Y.... Parvin J.D. (2004)
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External Searches for HIST1H2AM gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing HIST1H2AM gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HIST1H2AM gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HIST1H2AM gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for HIST1H2AM | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for HIST1H2AM gene: Search GeneIP for patents involving HIST1H2AM
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for HIST1H2AM gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HIST1H2AM | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HIST1H2AM | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIST1H2AM | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HIST1H2AM | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST1H2AM | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST1H2AM |
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