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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HIST1H1T Gene

protein-coding   GIFtS: 54
GCID: GC06M026107

histone cluster 1, H1t

(Previous names: H1 histone family, member T (testis-specific), histone...)
(Previous symbol: H1FT)
 Explore 3 diseases affiliated with
HIST1H1T via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for HIST1H1T    

Aliases
for HIST1H1T gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Histone Cluster 1, H1t1 2     Testicular H1 Histone2 3
H1FT1 2 3 5     DJ221C16.21
H1t1 2     Histone H1t2
H1 Histone Family, Member T (Testis-Specific)1 2     H1T3
Histone 1, H1t1 2     

External Ids:    HGNC: 47201   Entrez Gene: 30102   Ensembl: ENSG000001874757   OMIM: 1427125   UniProtKB: P224923   

Export aliases for HIST1H1T gene to outside databases

Previous GC identifers: GC06M026165 GC06M026215 GC06M026050


Summaries
for HIST1H1T gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for HIST1H1T:
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two
molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp
of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between
nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and
encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a
palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. (provided by
RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: H1T_HUMAN, P22492
Function: Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures

Gene Wiki entry for HIST1H1T


Genomic Views
for HIST1H1T gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HIST1H1T gene promoter:
         TBP   Elk-1   NF-YA   NRSF form 1   GCNF   NRSF form 2   TFIID   GCNF-1   GCNF-2   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: HIST1H1T promoter sequence
   Search SABiosciences Chromatin IP Primers for HIST1H1T

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIST1H1T


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p22.2   HGNC cytogenetic band: 6p22.1

HIST1H1T Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HIST1H1T gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M026107:  view genomic region     (about GC identifiers)

Start:
 26,107,640 bp from pter      End:
 26,108,364 bp from pter
Size:
 725 bases      Orientation:
 minus strand

Proteins
for HIST1H1T gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: H1T_HUMAN, P22492 (See protein sequence)
Recommended Name: Histone H1t  
Size: 207 amino acids; 22019 Da
Subcellular location: Nucleus. Chromosome
Developmental stage: This histone is a testis-specific H1 variant that appears during meiosis in spermatogenesis
Secondary accessions: Q6ISI1 Q8IUE8

Explore the universe of human proteins at neXtProt for HIST1H1T: NX_P22492

Post-translational modifications:

  • Phosphorylated in early spermatids (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P22492

    • HIST1H1T Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_005314.2  
    ENSEMBL proteins: 
     ENSP00000341214  

    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: HIST1H1T
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    Browse Sino Biological Recombinant Proteins
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    Uscn Proteins for HIST1H1T

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000786nucleosome IEA--
    GO:0000794condensed nuclear chromosome IEA--
    GO:0005622intracellular ----


    HIST1H1T for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for HIST1H1T

    Protein Domains /
    Families
    for HIST1H1T gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HIST1H1T for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR005819 Histone_H5
     IPR011991 WHTH_trsnscrt_rep_DNA-bd_dom
     IPR005818 Histone_H1/H5

    Graphical View of Domain Structure for InterPro Entry P22492

    ProtoNet protein and cluster: P22492

    1 Blocks protein family: IPB005818 Histone H1/H5

    UniProtKB/Swiss-Prot: H1T_HUMAN, P22492
    Similarity: Belongs to the histone H1/H5 family
    Similarity: Contains 1 H15 (linker histone H1/H5 globular) domain


    Function
    for HIST1H1T gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: H1T_HUMAN, P22492
    Function: Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures

    miRNA
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    hsa-miR-1276
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    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HIST1H1T (see all 7)
    OriGene shRNA RFP: HIST1H1T
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for HIST1H1T

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--


    HIST1H1T for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for HIST1H1T:
     Lamellipodia cells 

    Animal Models:
         Mouse knock-outs for HIST1H1T: Hist1h1ttm1Ais Hist1h1ttm1Drab
         2 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Hist1h1t):
     normal  reproductive system 

    HIST1H1T for phenotypes           About GeneDecksing


    Pathways & Interactions
    for HIST1H1T gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cell cycle_Start of DNA replication in early S phase
    		Cell cycle_Start of DNA replication in early S phase1.00
    		Cell cycle Start of DNA replication in early S phase0.98
    2Cell cycle Chromosome condensation in prometaphase
    		Cell cycle Chromosome condensation in prometaphase1.00
    		Cell cycle_Chromosome condensation in prometaphase1.00
    3Activation of cAMP-Dependent PKA
    		PKA Signaling0.56
    4Activation of DNA fragmentation factor
    		Granzyme-A Pathway0.32
    5Signal transduction Activin A signaling regulation
    		Histone modification0.31

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    3 EMD Millipore Pathways for HIST1H1T
        Histone modification
    Cell cycle Start of DNA replication in early S phase
    Cell cycle Chromosome condensation in prometaphase

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for HIST1H1T
        PKA Signaling
    Granzyme-A Pathway

    2 GeneGo (Thomson Reuters) Pathways for HIST1H1T
        Cell cycle Chromosome condensation in prometaphase
    Cell cycle Start of DNA replication in early S phase



    HIST1H1T for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HIST1H1T

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/78 Interacting proteins for HIST1H1T (P224922, 3 ENSP000003412144) via UniProtKB, MINT, STRING, and/or I2D (see all 78)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAQP273482, 3, ENSP000002380814MINT-7899812 I2D: score=1 STRING: ENSP00000238081
    GSK3BP498413, ENSP000003248064I2D: score=1 STRING: ENSP00000324806
    YWHAZP631042, ENSP000003095034MINT-7899812 STRING: ENSP00000309503
    POU5F1Q018603I2D: score=1 
    ACTA2P627362MINT-7899812
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006334nucleosome assembly IEA--
    GO:0007275multicellular organismal development IEA--
    GO:0007283spermatogenesis IEA--
    GO:0007339binding of sperm to zona pellucida IEA--
    GO:0030154cell differentiation IEA--


    HIST1H1T for ontologies           About GeneDecksing



    Drugs & Compounds
    for HIST1H1T gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    HIST1H1T for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for HIST1H1T
    1 Novoseek chemical compound relationship for HIST1H1T gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    protamine 59.8 2 12920187 (2)

    Search CenterWatch for drugs/clinical trials and news about HIST1H1T / H1T 

    Transcripts
    for HIST1H1T gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for HIST1H1T gene: 
    NM_005323.3  

    Unigene Cluster for HIST1H1T:

    Histone cluster 1, H1t
    Hs.533293  [show with all ESTs]
    Unigene Representative Sequence: NM_005323
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000338379(uc003ngj.3)

    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate HIST1H1T:
    hsa-miR-1276
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HIST1H1T (see all 7)
    OriGene shRNA RFP: HIST1H1T
    OriGene siRNA: HIST1H1T
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HIST1H1T
    Clone
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    GenScript: all cDNA clones in your preferred vector: HIST1H1T (NM_005323)
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    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HIST1H1T
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIST1H1T
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HIST1H1T

    Additional cDNA sequence: 

    BC069517.1 BC130350.1 

    1 DOTS entry:

    DT.404525 

    5 AceView cDNA sequences:

    NM_005323 BC069517 BP369074 BV198254 BV183498 

    GeneLoc Exon Structure


    Expression
    for HIST1H1T gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HIST1H1T expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAGTTAATGT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    HIST1H1T expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    4 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    TestisSeminiferous TubulesSecondary SpermatocyteGerm Cells, Male Gametocytes
    BrainHypothalamusBrain
    Neural TubeDiencephalic Ventricular ZoneNeural Tube
    Neural TubeMesencephalic Ventricular ZoneNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    ES-J1 (Embryonic Stem Cell)Early Embryo, Inner Cell Mass
    Long-time differentiated EBs (Derivation of embryo...)

    See HIST1H1T Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HIST1H1T

    SOURCE GeneReport for Unigene cluster: Hs.533293
        SABiosciences Custom PCR Arrays for HIST1H1T
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HIST1H1T

    Orthologs
    for HIST1H1T gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for HIST1H1T gene from 7/22 species (see all 22)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves F1NME1_CHICK6
    F1NPJ2_CHICK6
    (see all 5)    		 Uncharacterized protein
    (see all 5)    		 47(a)
    47(a)
    (see all 5)    		 many ↔ many
    many ↔ many
    (see all 5)    		 1(50050557-50051216)
    1(49946004-49946660)
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    (see all 4)    		 --
    		 74(a)
    44(a)
    (see all 4)    		 many ↔ many
    many ↔ many
    (see all 4)    		 GL343400.1(426161-426382)
    GL343279.1(541498-542142)
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc:1630616
    zgc:1630616
    (see all 15)    		 zgc:163061
    (see all 15)    		 54(a)
    54(a)
    (see all 15)    		 many ↔ many
    many ↔ many
    (see all 15)    		 7(76848733-76849489)
    7(76823085-76823497)
    fruit fly
    (Drosophila melanogaster)    		 Insecta His1:CG316176
    His1:CG338286
    (see all 23)    		 His1:CG33828
    (see all 23)    		 21(a)
    21(a)
    (see all 23)    		 many ↔ many
    many ↔ many
    (see all 23)    		 2L(21421980-21422877)
    2L(21476427-21477324)
    worm
    (Caenorhabditis elegans)    		 Secernentea hil-16
    		 Histone H1.X
    		 13(a)
    		 possible ortholog
    		 V(14949760-14952775)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons HIS1-36
    AT1G067606
    (see all 3)    		 histone H1.1
    (see all 3)    		 21(a)
    13(a)
    (see all 3)    		 many ↔ many
    many ↔ many
    (see all 3)    		 2(7845923-7846884)
    1(2076504-2077698)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    (see all 4)    		 histone H1, putative, expressed
    (see all 4)    		 18(a)
    13(a)
    (see all 4)    		 many ↔ many
    many ↔ many
    (see all 4)    		 4(9984198-9985211)
    6(1641215-1642801)


    ENSEMBL Gene Tree for HIST1H1T (if available)
    TreeFam Gene Tree for HIST1H1T (if available) 

    Paralogs
    for HIST1H1T gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HIST1H1T gene
    HIST1H1D2  H1F02  H1FOO2  HIST1H1E2  HIST1H1C2  HIST1H1B2  H1FX2  HIST1H1A2  
    6 SIMAP similar genes for HIST1H1T using alignment to 2 protein entries:     H1T_HUMAN (see all proteins):
    HIST1H1B    HIST1H1E    HIST1H1A    HIST1H1C    HIST1H1D    H1F0

    HIST1H1T for paralogs           About GeneDecksing



    Genomic Variants
    for HIST1H1T gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/123 NCBI SNPs in HIST1H1T are shown (see all 123)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs769797891,2
    		C,--26107185(+) TACCAC/TGGACC 1 -- ds50010--------
    rs1863483901,2
    		--26107189(+) ACGGAA/CCAGGG 1 -- ds50010--------
    rs94676741,2
    		F,--26107265(+) agattG/Ttcaca 1 -- ds50011Minor allele frequency- T:0.03WA 118
    rs1902658321,2
    		--26107275(+) AAGGAA/GCCTGA 1 -- ds50010--------
    rs1828499841,2
    		--26107295(+) CCCTTC/GCATGT 1 -- ds50010--------
    rs20515431,2
    		C,F,A,H,--26107331(-) TAGATT/ACTCAT 1 -- ds500113Minor allele frequency- A:0.31NS EA WA NA 1202
    rs768117491,2
    		C--26107363(+) ACAGGC/TGGTGG 1 -- ds50010--------
    rs1417362901,2
    		--26107389(+) TGTTCA/GCTCAC 1 -- ds50010--------
    rs1454670561,2
    		--26107426(+) ACGTGC/TCATGG 1 -- ds50010--------
    rs1476868841,2
    		--26107458(+) GTGGCA/CGGGGA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for HIST1H1T (26107640 - 26108364 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for HIST1H1T: --

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    Disorders / Diseases
    for HIST1H1T gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    HIST1H1T for disorders           About GeneDecksing

    OMIM gene information: 142712    OMIM disorders: --

    3 diseases for HIST1H1T:    About MalaCards
    childhood leukemia    hemochromatosis    leukemia

    Human Genome Epidemiology (HuGE) Navigator: HIST1H1T (2 documents)

    Export disorders for HIST1H1T gene to outside databases

    Publications
    for HIST1H1T gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HIST1H1T gene, integrated from 9 sources (see all 41):
    (articles sorted by number of sources associating them with HIST1H1T)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The human and mouse replication-dependent histone genes. (PubMed id 12408966)1, 2, 3 Marzluff W.F....Maltais L.J. (2002)
    2. Primate testicular histone H1t genes are highly conserved and the human H1t gene is located on chromosome 6. (PubMed id 8175896)1, 2, 3 Koppel D.A.... Grimes S.R. (1994)
    3. Structure and expression of the human gene encoding testicular H1 histone (H1t). (PubMed id 1889752)1, 2, 9 Drabent B.... Doenecke D. (1991)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Expression of mRNA and protein of nucleoproteins during human spermiogenesis. (PubMed id 9809674)1, 9 Steger K....Bergmann M. (1998)
    6. Human histone gene organization: nonregular arrangement within a large cluster. (PubMed id 9119399)1, 9 Albig W.... Doenecke D. (1997)
    7. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    8. Integrative analysis of the ubiquitin proteome isolat ed using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (2011)
    9. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    10. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. (PubMed id 21909110)1 Wain L.V....van Duijn C.M. (2011)

    External Searches for HIST1H1T gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing HIST1H1T gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3010 HGNC: 4720 AceView: HIST1H1T Ensembl:ENSG00000187475 euGenes: HUgn3010
    ECgene: HIST1H1T H-InvDB: HIST1H1T

    Other Databases showing HIST1H1T gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing HIST1H1T gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HIST1H1T Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for HIST1H1T gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for HIST1H1T gene:
    Search GeneIP for patents involving HIST1H1T

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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