Aliases for HIST1H1T Gene
External Ids for HIST1H1T Gene
Previous Symbols for HIST1H1T Gene
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Jul 2008]
GeneCards Summary for HIST1H1T Gene
HIST1H1T (Histone Cluster 1, H1t) is a Protein Coding gene. Among its related pathways are Activation of cAMP-Dependent PKA and E2F mediated regulation of DNA replication. An important paralog of this gene is HIST1H1D.
UniProtKB/Swiss-Prot for HIST1H1T Gene
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures