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HIST1H1D Gene

protein-coding   GIFtS: 61
GCID: GC06M026234

Histone Cluster 1, H1d

(Previous names: H1 histone family, member 3, histone 1, H1d)
(Previous symbol: H1F3)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Histone Cluster 1, H1d1 2     Histone H1s-22 3
H1F31 2 3 5     H1.32
H1 Histone Family, Member 31 2     H1D2
Histone 1, H1d1 2     H1s-22
Histone H1c2 3     Histone H1.32

External Ids:    HGNC: 47171   Entrez Gene: 30072   Ensembl: ENSG000001245757   OMIM: 1422105   UniProtKB: P164023   

Export aliases for HIST1H1D gene to outside databases

Previous GC identifers: GC06M026291 GC06M026118 GC06M026342 GC06M026177


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HIST1H1D Gene:
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes.
Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which
approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts
with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.
This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA
tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster
on chromosome 6. (provided by RefSeq, Jul 2008)

GeneCards Summary for HIST1H1D Gene:
HIST1H1D (histone cluster 1, H1d) is a protein-coding gene. Diseases associated with HIST1H1D include paratyphoid fever, and typhoid fever. An important paralog of this gene is HIST1H1T.

UniProtKB/Swiss-Prot: H13_HUMAN, P16402
Function: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as
the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order
structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling,
nucleosome spacing and DNA methylation (By similarity)

Gene Wiki entry for HIST1H1D Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NC_018917.2  NT_007592.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the HIST1H1D gene promoter:
         SRF   GR   SRF (504 AA)   GR-beta   AREB6   E2F-1   E2F   ARP-1   STAT3   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHIST1H1D promoter sequence
   Search Chromatin IP Primers for HIST1H1D

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HIST1H1D


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p22.2   HGNC cytogenetic band: 6p21.3

HIST1H1D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HIST1H1D gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M026234:  view genomic region     (about GC identifiers)

Start:
26,234,440 bp from pter      End:
26,235,216 bp from pter
Size:
777 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: H13_HUMAN, P16402 (See protein sequence)
Recommended Name: Histone H1.3  
Size: 221 amino acids; 22350 Da
Secondary accessions: B2R751 Q2M2I2

Explore the universe of human proteins at neXtProt for HIST1H1D: NX_P16402

Explore proteomics data for HIST1H1D at MOPED

Post-translational modifications: 

  • H1 histones are progressively phosphorylated during the cell cycle, becoming maximally phosphorylated during late
    G2 phase and M phase, and being dephosphorylated sharply thereafter (By similarity)1
  • Citrullination at Arg-55 (H1R54ci) by PADI4 takes place within the DNA-binding site of H1 and results in its
    displacement from chromatin and global chromatin decondensation, thereby promoting pluripotency and stem cell
    maintenance (By similarity)1
  • Ubiquitination2 at Lys35, Lys47, Lys64, Lys65, Lys76, Lys86, Lys91, Lys98, Lys107
  • Modification sites at PhosphoSitePlus

  • See HIST1H1D Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005311.1  
    ENSEMBL proteins: 
     ENSP00000244534  
    Reactome Protein details: P16402

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    HIST: Histones / Replication-dependent

    3 InterPro protein domains:
     IPR005819 Histone_H5
     IPR011991 WHTH_DNA-bd_dom
     IPR005818 Histone_H1/H5_H15

    Graphical View of Domain Structure for InterPro Entry P16402

    ProtoNet protein and cluster: P16402

    1 Blocks protein domain: IPB005818 Histone H1/H5

    UniProtKB/Swiss-Prot: H13_HUMAN, P16402
    Domain: The C-terminal domain is required for high-affinity binding to chromatin (By similarity)
    Similarity: Belongs to the histone H1/H5 family
    Similarity: Contains 1 H15 (linker histone H1/H5 globular) domain


    HIST1H1D for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: H13_HUMAN, P16402
    Function: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as
    the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order
    structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling,
    nucleosome spacing and DNA methylation (By similarity)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0005515protein binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    HIST1H1D for ontologies           About GeneDecksing


    Phenotypes:
         10 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Hist1h1d):
     cardiovascular system  embryogenesis  growth/size/body  hematopoietic system  immune system 
     limbs/digits/tail  mortality/aging  nervous system  normal  reproductive system 

    HIST1H1D for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for HIST1H1D: Hist1h1dtm1Mkk Hist1h1dtm2Ais Hist1h1dtm1Ais

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HIST1H1D
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    miRNA
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    miRTarBase miRNAs that target HIST1H1D:
    hsa-mir-34a-5p (MIRT025402), hsa-mir-26b-5p (MIRT030222), hsa-let-7a-5p (MIRT052415), hsa-mir-193b-3p (MIRT016545)

    Block miRNA regulation of human, mouse, rat HIST1H1D using miScript Target Protectors
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    hsa-miR-146a* hsa-miR-1276 hsa-miR-1293
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HIST1H1D


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    H13_HUMAN, P16402: Nucleus. Chromosome. Note=According to PubMed:15911621 more commonly found in euchromatin.
    According to PubMed:10997781 is associated with inactive chromatin
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000786nucleosome IEA--
    GO:0000790nuclear chromatin IDA19882353
    GO:0005634nucleus ----

    HIST1H1D for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for HIST1H1D About   (see all 8)  
    See pathways by source

    SuperPathContained pathways About
    1Activation of DNA fragmentation factor
    Activation of DNA fragmentation factor0.32
    Apoptosis induced DNA fragmentation0.00
    Granzyme-A Pathway0.32
    2Packaging Of Telomere Ends
    DNA Damage/Telomere Stress Induced Senescence0.65
    Formation of Senescence-Associated Heterochromatin Foci (SAHF)0.00
    Histone modification0.31
    3Cellular Senescence
    Cellular Senescence0.81
    Cellular responses to stress0.81
    4Apoptotic cleavage of cellular proteins
    Apoptotic execution phase0.74
    5Activation of cAMP-Dependent PKA
    PKA Signaling0.56

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for HIST1H1D
        PKA Signaling
    Granzyme-A Pathway

    2 GeneGo (Thomson Reuters) Pathways for HIST1H1D
        Cell cycle Chromosome condensation in prometaphase
    Cell cycle Start of DNA replication in early S phase

    2 Reactome Pathways for HIST1H1D
        Activation of DNA fragmentation factor
    Formation of Senescence-Associated Heterochromatin Foci (SAHF)



    HIST1H1D for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HIST1H1D
    Interactions:

        Search GeneGlobe Interaction Network for HIST1H1D

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    Selected Interacting proteins for HIST1H1D (P164022, 3 ENSP000002445344) via UniProtKB, MINT, STRING, and/or I2D (see all 100)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LMNAP025452, 3MINT-7899812 I2D: score=1 
    YWHAQP273482, 3, ENSP000002380814MINT-7899812 I2D: score=1 STRING: ENSP00000238081
    EP300Q094723, ENSP000002632534I2D: score=1 STRING: ENSP00000263253
    SUMO1P631653, ENSP000003760764I2D: score=1 STRING: ENSP00000376076
    NOP56O005673, ENSP000003705894I2D: score=1 STRING: ENSP00000370589
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    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006334nucleosome assembly IEA--
    GO:0016584nucleosome positioning IEA--

    HIST1H1D for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HIST1H1D (H13)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for HIST1H1D gene: 
    NM_005320.2  

    Unigene Cluster for HIST1H1D:

    Histone cluster 1, H1d
    Hs.136857  [show with all ESTs]
    Unigene Representative Sequence: NM_005320
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000244534(uc003nhd.3)
    miRNA
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      QuantiFast Probe-based Assays in human, mouse, rat HIST1H1D

    Additional mRNA sequence: 

    AK312845.1 BC104874.1 BC111971.1 

    1 DOTS entry:

    DT.439911 

    6 AceView cDNA sequences:

    NM_005320 BX107129 BG943891 AA749093 AA767038 BG230976 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HIST1H1D expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCGGAGACTG
    HIST1H1D Expression
    About this image


    HIST1H1D expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 5 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Mesencephalic Ventricular Zone
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    HIST1H1D Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HIST1H1D Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.136857
        Custom PCR Arrays for HIST1H1D
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for HIST1H1D gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hist1h1d1 , 5 histone cluster 1, H1d1, 5 80.84(n)1
    91.02(a)1
      13 (9.79 cM)5
    149571  NM_145713.31  NP_663759.31 
     235550875 
    chicken
    (Gallus gallus)
    Aves HIST1H111L6
    HIST1H111R6
    (see all 3)
    Gallus gallus histone cluster 1, H1.11L (similar t...
    Gallus gallus histone cluster 1, H1.11R (similar t...
    (see all 3)
    71(a)
    70(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    1(48025516-48026285)
    1(48033617-48034276)
    zebrafish
    (Danio rerio)
    Actinopterygii CU457819.36
    CABZ01086354.16
    (see all 15)
    Uncharacterized protein
    (see all 15)
    67(a)
    67(a)
    (see all 15)
    many ↔ many
    many ↔ many
    (see all 15)
    7(7179641-7180171) ENSDARG00000090426
    25(36182655-36183146) ENSDARG00000092395


    ENSEMBL Gene Tree for HIST1H1D (if available)
    TreeFam Gene Tree for HIST1H1D (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HIST1H1D gene
    HIST1H1T2  HIST1H1E2  H1F02  HIST1H1B2  HIST1H1C2  HIST1H1A2  
    7 SIMAP similar genes for HIST1H1D using alignment to 1 protein entry:     H13_HUMAN:
    HIST1H1E    HIST1H1C    HIST1H1B    HIST1H1A    HIST1H1T    H1F0
    H1FX

    HIST1H1D for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HIST1H1D (see all 174)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1406364591,2
    C,Funtested126234970(+) GCTTTC/TTTAAG 2 K syn11Minor allele frequency- T:0.00NA 4542
    rs1498540421,2
    --26233945(+) AAAGGC/TCTGCG 1 -- ds50010--------
    rs1504184241,2
    C--26233999(+) GACCA-/GCTGCTGC 1 -- cds10--------
    rs1179310501,2
    F--26234040(+) ATGCCA/GCGTAC 1 -- ds50011Minor allele frequency- G:0.04EA 120
    rs1141179431,2
    C,F--26234042(+) GCCACG/TTACTG 1 -- ds50011Minor allele frequency- T:0.03WA 118
    rs1137997421,2
    F--26234121(+) ACATCC/TCTGTG 1 -- ds50011Minor allele frequency- T:0.50CSA 2
    rs168914561,2
    C,F--26234127(+) CTGTGT/CCAGAA 1 -- ds50018Minor allele frequency- C:0.13NA CSA WA EA 504
    rs1918729061,2
    --26234166(+) CGCCGC/TGCTTT 1 -- ds50010--------
    rs1490061721,2
    --26234235(+) CTGGTA/GGCTCA 1 -- ds50010--------
    rs1437787461,2
    C--26234294(+) TCCTTA/GCGCCC 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for HIST1H1D (26234440 - 26235216 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for HIST1H1D:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv428137CNV Loss18775914

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HIST1H1D
    DNA2.0 Custom Variant and Variant Library Synthesis for HIST1H1D

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 142210    OMIM disorders: --

    11 diseases for HIST1H1D:    
    About MalaCards
    paratyphoid fever    typhoid fever    treacher collins syndrome    crohn's disease
    meningioma    tonsillitis    endotheliitis    neuroblastoma
    cerebritis    thyroiditis    prostatitis

    2 diseases from the University of Copenhagen DISEASES database for HIST1H1D:
    Typhoid fever     Paratyphoid fever

    HIST1H1D for disorders           About GeneDecksing

    Genetic Association Database (GAD): HIST1H1D
    Human Genome Epidemiology (HuGE) Navigator: HIST1H1D (5 documents)

    Export disorders for HIST1H1D gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HIST1H1D gene, integrated from 10 sources (see all 65):
    (articles sorted by number of sources associating them with HIST1H1D)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human and mouse replication-dependent histone genes. (PubMed id 12408966)1, 2, 3 Marzluff W.F.... Maltais L.J. (Genomics 2002)
    2. Isolation and characterization of two human H1 histone genes within clusters of core histone genes. (PubMed id 1916825)1, 2, 3 Albig W.... Doenecke D. (Genomics 1991)
    3. Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study. (PubMed id 20846217)1, 4 Lee J.J....Hirschhorn J. (Ann. Hum. Genet. 2010)
    4. Identification of 15 loci influencing height in a Korean population. (PubMed id 19893584)1, 4 Kim J.J....Lee J.K. (J. Hum. Genet. 2010)
    5. Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966. (PubMed id 19266077)1, 4 Sovio U....Jarvelin M.R. (PLoS Genet. 2009)
    6. Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. (PubMed id 19343178)1, 4 Soranzo N....Deloukas P. (PLoS Genet. 2009)
    7. Identification of ten loci associated with height highlights new biological pathways in human growth. (PubMed id 18391950)1, 4 Lettre G.... Hirschhorn J.N. (Nat. Genet. 2008)
    8. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 3007 HGNC: 4717 AceView: HIST1H1D Ensembl:ENSG00000124575 euGenes: HUgn3007
    ECgene: HIST1H1D H-InvDB: HIST1H1D

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for HIST1H1D Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for HIST1H1D gene:
    Search GeneIP for patents involving HIST1H1D

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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