External Ids for HIRIP3 Gene
Previous GeneCards Identifiers for HIRIP3 Gene
The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Aug 2011]
GeneCards Summary for HIRIP3 Gene
HIRIP3 (HIRA Interacting Protein 3) is a Protein Coding gene. Diseases associated with HIRIP3 include velocardiofacial syndrome.
UniProtKB/Swiss-Prot for HIRIP3 Gene
May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones.