Aliases for HIP1R Gene
External Ids for HIP1R Gene
Previous GeneCards Identifiers for HIP1R Gene
GeneCards Summary for HIP1R Gene
HIP1R (Huntingtin Interacting Protein 1 Related) is a Protein Coding gene. Among its related pathways are Vesicle-mediated transport and Delta508-CFTR traffic / ER-to-Golgi in CF. GO annotations related to this gene include actin binding and phosphatidylinositol binding. An important paralog of this gene is HIP1.
UniProtKB/Swiss-Prot for HIP1R Gene
Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.