Aliases for HINFP Gene
External Ids for HINFP Gene
Previous HGNC Symbols for HINFP Gene
Previous GeneCards Identifiers for HINFP Gene
This gene encodes a transcription factor that interacts with methyl-CpG-binding protein-2 (MBD2), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Aug 2011]
GeneCards Summary for HINFP Gene
HINFP (Histone H4 Transcription Factor) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and enzyme binding. An important paralog of this gene is CTCFL.
UniProtKB/Swiss-Prot for HINFP Gene
Transcriptional repressor that binds to the consensus sequence 5-CGGACGTT-3 and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter.