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HILPDA Gene

protein-coding   GIFtS: 37
GCID: GC07P128123

Hypoxia Inducible Lipid Droplet-Associated

(Previous name: chromosome 7 open reading frame 68)
(Previous symbol: C7orf68)
  See HILPDA-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Hypoxia Inducible Lipid Droplet-Associated1 2     Chromosome 7 Open Reading Frame 681
C7orf681 2 3     HIG-22
Hypoxia Inducible Gene 21 2     Hypoxia-Inducible Lipid Droplet-Associated Protein2
Hypoxia-Inducible Gene 2 Protein2 3     Hypoxia-Inducible Protein 22
HIG22 3     

External Ids:    HGNC: 288591   Entrez Gene: 299232   Ensembl: ENSG000001352457   UniProtKB: Q9Y5L23   
ORGUL members:         

Export aliases for HILPDA gene to outside databases

Previous GC identifers: GC07P128109 GC07P128112 GC07P128115 GC07P128117


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for HILPDA Gene:
HILPDA (hypoxia inducible lipid droplet-associated) is a protein-coding gene. Diseases associated with HILPDA include end stage renal failure, and hypoxia. GO annotations related to this gene include receptor binding.

UniProtKB/Swiss-Prot: HLPDA_HUMAN, Q9Y5L2
Function: Increases intracellular lipid accumulation. Stimulates expression of cytokines including IL6, MIF and
VEGFA. Enhances cell growth and proliferation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Search for regulatory transcription factor binding sites for HILPDA
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): HILPDA promoter sequence
   Search Chromatin IP Primers for HILPDA

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HILPDA


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q32.1   Ensembl cytogenetic band:  7q32.1   HGNC cytogenetic band: 7q32.1

HILPDA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HILPDA gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P128123:  view genomic region     (about GC identifiers)

Start:
128,095,884 bp from pter      End:
128,098,472 bp from pter
Size:
2,589 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 127,478,995-127,481,583     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HLPDA_HUMAN, Q9Y5L2 (See protein sequence)
Recommended Name: Hypoxia-inducible lipid droplet-associated protein  
Size: 63 amino acids; 6950 Da
Secondary accessions: A4D0Z5 Q52LY5 Q53HJ7

Explore the universe of human proteins at neXtProt for HILPDA: NX_Q9Y5L2

Explore proteomics data for HILPDA at MOPED

Post-translational modifications: 

  • Glycosylation2 at Ser44, Thr49, Thr52, Ser60, Ser62
  • Modification sites at PhosphoSitePlus

  • See HILPDA Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001092256.1  NP_037464.1  

    ENSEMBL proteins: 
     ENSP00000388871   ENSP00000257696  

    HILPDA Human Recombinant Protein Products:

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    Search eBioscience for ELISAs for HILPDA 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026190 Hipoxia_HILPDA

    Graphical View of Domain Structure for InterPro Entry Q9Y5L2

    ProtoNet protein and cluster: Q9Y5L2


    Find genes that share domains with HILPDA           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HLPDA_HUMAN, Q9Y5L2
    Function: Increases intracellular lipid accumulation. Stimulates expression of cytokines including IL6, MIF and
    VEGFA. Enhances cell growth and proliferation
    Induction: By hypoxia but highly abundant under normoxic conditions (at protein level)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005102receptor binding IPI15930302
    GO:0005515protein binding IPI15930302
         
    Find genes that share ontologies with HILPDA           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Hilpda):
     no phenotypic analysis 

    Find genes that share phenotypes with HILPDA           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Hilpdatm1.1Nat for HILPDA

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HILPDA
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for HILPDA

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HILPDA
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HILPDA

    miRNA
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    Block miRNA regulation of human, mouse, rat HILPDA using miScript Target Protectors
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    SwitchGear 3'UTR luciferase reporter plasmidHILPDA 3' UTR sequence
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    Predesigned siRNA for gene silencing in human, mouse, rat HILPDA

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HLPDA_HUMAN, Q9Y5L2: Lipid droplet. Secreted. Membrane; Single-pass membrane protein (Potential)

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA15930302
    GO:0005811lipid particle IDA--
    GO:0009986cell surface IDA15930302
    GO:0016021integral component of membrane IEA--
    GO:0030141secretory granule IDA15930302

    Find genes that share ontologies with HILPDA           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HILPDA
    Interactions:

        Search GeneGlobe Interaction Network for HILPDA

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for HILPDA (Q9Y5L21 ENSP000002576964) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FZD10Q9ULW21EBI-8803836,EBI-8803802
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001819positive regulation of cytokine production IDA--
    GO:0006950response to stress NAS10690527
    GO:0008284positive regulation of cell proliferation IDA15930302
    GO:0010884positive regulation of lipid storage IDA--
    GO:0035425autocrine signaling IDA15930302

    Find genes that share ontologies with HILPDA           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HILPDA (HLPDA)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HILPDA gene (2 alternative transcripts): 
    NM_001098786.1  NM_013332.3  

    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000435296 ENST00000257696(uc003vne.4 uc010lli.3) ENST00000481454
    ENST00000466473
    miRNA
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    Block miRNA regulation of human, mouse, rat HILPDA using miScript Target Protectors
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    SwitchGear 3'UTR luciferase reporter plasmidHILPDA 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for HILPDA
    Predesigned siRNA for gene silencing in human, mouse, rat HILPDA
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    Primer
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    OriGene qPCR primer pairs and template standards for HILPDA
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      QuantiTect SYBR Green Assays in human, mouse, rat HILPDA
      QuantiFast Probe-based Assays in human, mouse, rat HILPDA

    Selected AceView cDNA sequences (see all 340):

    BX358476 N67103 CA841693 BQ012410 BM763955 BX094542 CD514136 BG391280 
    BM764811 BF477370 AW082974 BG110390 BQ011771 CR623904 CR598155 CA426397 
    CA841985 BE068262 BF726610 BX281217 AI948588 BX093239 BM546738 BG682088 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HILPDA expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGCTTAAAT
    HILPDA Expression
    About this image


    HILPDA expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Umbilical Cord (Extraembryonic Tissues)    fully expand to see all 2 entries
             Umbilical cord blood-derived hematopoietic stem cells
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Umbilical cord blood-derived hematopoietic stem cells
     
     Paraxial Mesoderm (Gastrulation Derivatives)
             PureStem SK11, NCr-fac & Meso-prx Progenitor
     
     Neural Crest (Gastrulation Derivatives)
             PureStem SK11, NCr-fac & Meso-prx Progenitor
     
     Ovary (Reproductive System)
    HILPDA Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HILPDA Protein Expression

    UniProtKB/Swiss-Prot: HLPDA_HUMAN, Q9Y5L2
    Tissue specificity: Highly expressed in renal cell carcinoma cells but barely detectable in adjacent normal kidney
    tissue. Detected in some cervical and endometrial cancers. Expression also detected in fetal kidney with little
    or no expression observed in normal adult heart, liver, lung, pancreas, prostate or spinal cord (at protein
    level)

        Custom PCR Arrays for HILPDA
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for HILPDA gene from Selected species (see all 3)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hilpda1 , 5 hypoxia inducible lipid droplet associated1, 5 77.78(n)1
    77.78(a)1
      6 (12.36 cM)5
    695731  NM_023516.51  NP_076005.11 
     292724885 


    ENSEMBL Gene Tree for HILPDA (if available)
    TreeFam Gene Tree for HILPDA (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HILPDA (see all 119)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1844944381,2
    --128093916(+) CAGGAA/CTAAAT 2 -- us2k10--------
    rs1485229201,2
    --128093935(+) AGGTAC/GCTACA 2 -- us2k10--------
    rs1169687511,2
    C,F--128094016(+) ACCTTT/CAGACA 2 -- us2k11Minor allele frequency- C:0.02NA 120
    rs1890149341,2
    --128094023(+) GACAAC/TGGCAG 2 -- us2k10--------
    rs787326311,2
    C,F--128094066(+) GCCCAT/GCCCTT 2 -- us2k11Minor allele frequency- G:0.05WA 118
    rs758918891,2
    C,F--128094069(+) CATCCC/GTTCTT 2 -- us2k11Minor allele frequency- G:0.05WA 118
    rs27323911,2
    C,F--128094142(+) ATTCCT/CGCATT 2 -- us2k11Minor allele frequency- C:0.11WA 118
    rs1158183291,2
    C,F--128094251(+) GTGCCA/CGGCAT 2 -- us2k11Minor allele frequency- C:0.02WA 118
    rs25627281,2
    C,F,H--128094322(+) cacagA/Gacagc 2 -- us2k15Minor allele frequency- G:0.02NS EA WA 536
    rs1932693021,2
    --128094552(+) TGCCTA/GCCTGC 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for HILPDA (128095884 - 128098472 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for HILPDA: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HILPDA
    DNA2.0 Custom Variant and Variant Library Synthesis for HILPDA

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for HILPDA:    
    About MalaCards
    end stage renal failure    hypoxia    mantle cell lymphoma


    Find genes that share disorders with HILPDA           About GenesLikeMe


    Export disorders for HILPDA gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HILPDA gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with HILPDA)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Hypoxia-inducible protein 2 (HIG2), a novel diagnostic marker for renal cell carcinoma and potential target for molecular therapy. (PubMed id 15930302)1, 2, 3, 9 Togashi A....Nakamura Y. (Cancer Res. 2005)
    2. Epigenetic regulation of gene expression in cervical cancer cells by the tumor microenvironment. (PubMed id 10690527)1, 2, 3 Denko N.C....Giaccia A.J. (Clin. Cancer Res. 2000)
    3. Expression of hypoxia-inducible 2 (HIG2) protein in uterine cancer. (PubMed id 21614900)1, 2 Nishimura S.... Aoki D. (Eur. J. Gynaecol. Oncol. 2011)
    4. Hypoxia-inducible protein 2 is a novel lipid droplet protein and a specific target gene of hypoxia-inducible factor-1. (PubMed id 20624928)1, 2 Gimm T.... Warnecke C. (FASEB J. 2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)
    7. Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1alpha and nuclear factor kappaB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure. (PubMed id 18550099)1, 9 Konda R....Fujioka T. (J. Urol. 2008)
    8. Differential expression of hypoxia-inducible protein 2 among different histological types of epithelial ovarian cancer and in clear cell adenocarcinomas. (PubMed id 20134266)1, 9 Nishimura S....Aoki D. (Int. J. Gynecol. Cancer 2010)
    9. HIG2 promotes colorectal cancer progression via hypoxia-dependent and independent pathways. (PubMed id 23916472)1 Kim S.H....DuBois R.N. (Cancer Lett. 2013)
    10. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 29923 HGNC: 28859 AceView: HIG2andMETTL2andLOC441279 Ensembl:ENSG00000135245 euGenes: HUgn29923
    ECgene: HILPDA H-InvDB: HILPDA

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HILPDA Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HILPDA gene:
    Search GeneIP for patents involving HILPDA

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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for HILPDA  
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     QuantiFast Probe-based Assays in human, mouse, rat HILPDA QuantiTect SYBR Green Assays in human, mouse, rat HILPDA
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     Search Tocris compounds for HILPDA (HLPDA)
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     Browse ESI BIO Cell Lines and PureStem Progenitors for HILPDA
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     Search Addgene for plasmids for HILPDA
      Search eBioscience for proteins for HILPDA
      Search eBioscience for elisas for HILPDA
      eBioscience FlowRNA Probe Sets
           
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