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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HIGD1A Gene

protein-coding   GIFtS: 48
GCID: GC03M042801

HIG1 Hypoxia Inducible Domain Family, Member 1A

(Previous names: HIG1 domain family, member 1A)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
HIG1 Hypoxia Inducible Domain Family, Member 1A1 2     HIG12 3
HIG1 Domain Family, Member 1A1 2     RCF1a2 3
Hypoxia Inducible Gene 11 2     RCF1 Homolog A2 3
Hypoxia-Inducible Gene 1 Protein2 3     HIG1 Domain Family Member 1A, Mitochondrial2

External Ids:    HGNC: 295271   Entrez Gene: 259942   Ensembl: ENSG000001810617   UniProtKB: Q9Y2413   

Export aliases for HIGD1A gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for HIGD1A Gene: 
HIGD1A (HIG1 hypoxia inducible domain family, member 1A) is a protein-coding gene. Diseases associated with HIGD1A include hypoxia, and prostatic hypertrophy. An important paralog of this gene is HIGD1B.

UniProtKB/Swiss-Prot: HIG1A_HUMAN, Q9Y241
Function: Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the
mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May play a role in the assembly
of respiratory supercomplexes

Gene Wiki entry for HIGD1A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.2  NT_022517.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HIGD1A gene promoter:
         HOXA9B   HOXA9   LyF-1   Meis-1   Meis-1b   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHIGD1A promoter sequence
   Search SABiosciences Chromatin IP Primers for HIGD1A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIGD1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p22.1   Ensembl cytogenetic band:  3p22.1   HGNC cytogenetic band: 3p22.1

HIGD1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HIGD1A gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M042801:  view genomic region     (about GC identifiers)

Start:
42,798,669 bp from pter      End:
42,846,027 bp from pter
Size:
47,359 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HIG1A_HUMAN, Q9Y241 (See protein sequence)
Recommended Name: HIG1 domain family member 1A, mitochondrial  
Size: 93 amino acids; 10143 Da
Subunit: Associates with cytochrome c oxidase (COX, complex IV); proposed complex component. Also associates with
respratory chain supercomplexes
Subcellular location: Mitochondrion membrane; Multi-pass membrane protein. Mitochondrion inner membrane (Probable)
Sequence caution: Sequence=BG400624; Type=Frameshift; Positions=32;
1 PDB 3D structure from and Proteopedia for HIGD1A:
2LOM (3D)    
Secondary accessions: Q9UFZ2
Alternative splicing: 2 isoforms:  Q9Y241-1   Q9Y241-2   

Explore the universe of human proteins at neXtProt for HIGD1A: NX_Q9Y241

Explore proteomics data for HIGD1A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y241

  • HIGD1A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HIGD1A Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001093138.1  NP_001093139.1  NP_054775.2  

    ENSEMBL proteins: 
     ENSP00000406044   ENSP00000319393   ENSP00000402160   ENSP00000408289   ENSP00000398064  

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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for HIGD1A 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005743mitochondrial inner membrane IEA--
    GO:0016021integral to membrane IEA--
    GO:0043234protein complex IDA--
    GO:0070469respiratory chain IEA--

    HIGD1A for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR007667 Hypoxia_induced_domain

    Graphical View of Domain Structure for InterPro Entry Q9Y241

    ProtoNet protein and cluster: Q9Y241

    UniProtKB/Swiss-Prot: HIG1A_HUMAN, Q9Y241
    Similarity: Contains 1 HIG1 domain


    HIGD1A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HIG1A_HUMAN, Q9Y241
    Function: Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the
    mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May play a role in the assembly
    of respiratory supercomplexes
    Induction: By hypoxia

    Phenotypes:
         1 GenomeRNAi human phenotype for HIGD1A:

     Increased cell number in G2M,  

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for HIGD1A 
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    8/38 QIAGEN miScript miRNA Assays for microRNAs that regulate HIGD1A (see all 38):
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    SwitchGear 3'UTR luciferase reporter plasmidHIGD1A 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HIGD1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/9 Interacting proteins for HIGD1A (Q9Y2411, 3 ENSP000003980644) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CASP4P496621, 3, ENSP000003885664EBI-1051940,EBI-1057327 I2D: score=1 STRING: ENSP00000388566
    SNRPBP146781, 3EBI-1051940,EBI-372458 I2D: score=1 
    PAK7Q9P2861, 3, ENSP000003229574EBI-1051940,EBI-1051061 I2D: score=1 STRING: ENSP00000322957
    MYCP011063, ENSP000003672074I2D: score=3 STRING: ENSP00000367207
    USP32Q8NFA03, ENSP000003008964I2D: score=1 STRING: ENSP00000300896
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006950response to stress IEA--
    GO:0022900electron transport chain ----
    GO:0043066negative regulation of apoptotic process IDA--
    GO:0055114oxidation-reduction process IEA--

    HIGD1A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HIGD1A (HIG1A)

    Search CenterWatch for drugs/clinical trials and news about HIGD1A / HIG1A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HIGD1A gene (3 alternative transcripts): 
    NM_001099668.1  NM_001099669.1  NM_014056.3  

    Unigene Clusters for HIGD1A:

    HIG1 hypoxia inducible domain family, member 1A
    Hs.593134  [show with all ESTs], Hs.728813  [show with all ESTs]
    Unigene Representative Sequences: BF790812, AL833541
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000431549 ENST00000321331(uc010hid.3 uc003cma.4 uc003cmb.4)
    ENST00000418900 ENST00000470543 ENST00000430190 ENST00000452906
    miRNA
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    hsa-miR-596 hsa-miR-15a hsa-miR-4272 hsa-miR-3653 hsa-miR-138-2* hsa-miR-192 hsa-miR-4275 hsa-miR-424
    SwitchGear 3'UTR luciferase reporter plasmidHIGD1A 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HIGD1A
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    Additional mRNA sequence: 

    AF077034.1 AF145385.1 AK225571.1 AK311815.1 AL110233.1 AL833541.1 BC000601.1 BC009583.1 
    BC009594.1 BC070277.1 CR457385.1 

    24/42 DOTS entries (see all 42):

    DT.91680071  DT.100883119  DT.456275  DT.100883118  DT.91780356  DT.120860165  DT.100883126  DT.100883114 
    DT.410480  DT.100883128  DT.91780416  DT.100883123  DT.91780341  DT.120860055  DT.91780396  DT.120860210 
    DT.121118912  DT.100045267  DT.100883122  DT.100045266  DT.309429  DT.91780332  DT.100810305  DT.100883127 

    24/1403 AceView cDNA sequences (see all 1403):

    AV728134 CR612196 BM467994 BP363089 BG500902 BQ921580 AW328744 BM453919 
    T36026 AL543088 BG260730 CB987761 BM851278 BM564721 BQ643891 CR620520 
    Z41336 BM856231 AA315977 BU161597 BE905967 CR613730 BQ218326 BU508766 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for HIGD1A (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b
    SP1:                          -     -     -           -     -                           
    SP2:                          -           -                                             
    SP3:                          -     -     -                                             
    SP4:                          -     -     -     -     -     -                           
    SP5:                          -     -                 -     -                           


    ECgene alternative splicing isoforms for HIGD1A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HIGD1A expression in normal human tissues (normalized intensities)      HIGD1A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATCGGGAAT
    HIGD1A Expression
    About this image


    HIGD1A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Gut Tube (Gastrointestinal Tract)
             Definitive endoderm-like cells ( A scalable, suspension protocol for derivation of...
     
     Bone (Muscoskeletal System)
             BONE MARROW   
     
     Blood (Muscoskeletal System)
             BONE MARROW   
     
     Lower Urinary Tract (Urinary System)
             bladder   

    See HIGD1A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HIGD1A

    SOURCE GeneReport for Unigene clusters: Hs.593134 Hs.728813
        SABiosciences Custom PCR Arrays for HIGD1A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HIGD1A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for HIGD1A gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Higd1a5
    Gm149251
    HIG1 domain family, member 1A5
    predicted gene 149251
    78.5(n)1
    72.9(a)1
      9 (72.67 cM)5
    1005038081  XM_003085265.11  XP_003085313.11 
     1218485605 
    chicken
    (Gallus gallus)
    Aves HIGD1A1 HIG1 hypoxia inducible domain family, member 1A 69.88(n)
    73.49(a)
      768335  NM_001030957.1  NP_001026128.1 
    lizard
    (Anolis carolinensis)
    Reptilia HIGD1A6
    Uncharacterized protein
    74(a)
    1 ↔ 1
    GL343332.1(1387724-1392695)
    African clawed frog
    (Xenopus laevis)
    Amphibia AB095361.12   -- 76.47(n)    AB095361.1 
    zebrafish
    (Danio rerio)
    Actinopterygii AB094785.12   -- 72.2(n)   373084  AB094785.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG118256
    --
    29(a)
    1 → many
    2R(6307919-6309196)


    ENSEMBL Gene Tree for HIGD1A (if available)
    TreeFam Gene Tree for HIGD1A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HIGD1A gene
    HIGD1B2  HIGD1C2  
    4 SIMAP similar genes for HIGD1A using alignment to 3 protein entries:     HIG1A_HUMAN (see all proteins):
    HIGD1C    HIGD1B    HIGD2A    HIGD2B

    HIGD1A for paralogs           About GeneDecksing


    5/17 Pseudogenes.org Pseudogenes for HIGD1A (see all 17)
    PGOHUM00000242327 PGOHUM00000242605 PGOHUM00000239672 PGOHUM00000239771 PGOHUM00000239792


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/417 SNPs in HIGD1A are shown (see all 417)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1887448091,2
    --42823912(+) GTAAGA/CCCTTT 3 -- ds50010--------
    rs577597671,2
    C--42823967(+) ACTGTC/-CCCAT 3 -- ds50011Minor allele frequency- -:0.50CSA 2
    rs784037991,2
    C--42823970(+) GTCCCA/CATTTT 3 -- ds50010--------
    rs746352501,2
    C--42823971(+) TCCCCA/TTTTTA 3 -- ds50010--------
    rs1148158991,2
    C,F--42824017(+) CAGAAC/TCATGA 3 -- ds50011Minor allele frequency- T:0.10WA 118
    rs1928132921,2
    --42824088(+) TTACCA/GTTCTT 3 -- ds50010--------
    rs1841256441,2
    --42824371(+) ACTTAC/TGTAAG 3 -- ds50010--------
    rs1470992111,2
    C--42824392(+) ATGAC-/TTTTAG 3 -- ds50010--------
    rs1470622841,2
    --42824598(+) GGGAAC/TGTTTT 3 -- ut310--------
    rs1898885211,2
    --42824748(+) CAATAA/GTAGTT 3 -- ut310--------

    HapMap Linkage Disequilibrium report for HIGD1A (42798669 - 42846027 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for HIGD1A:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv435763CNV Deletion17901297
    esv1232041CNV Deletion17803354
    esv2725200CNV Deletion23290073
    esv4812CNV Deletion18987735
    esv1004289CNV Deletion20482838
    nsv236207CNV Loss16902084
    esv6998CNV Loss19470904
    nsv513043CNV Loss21212237

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    5 diseases for HIGD1A:    About MalaCards
    hypoxia    prostatic hypertrophy    cervical cancer    cervicitis
    prostatitis


    HIGD1A for disorders           About GeneDecksing

    Genetic Association Database (GAD): HIGD1A
    Human Genome Epidemiology (HuGE) Navigator: HIGD1A (1 document)

    Export disorders for HIGD1A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HIGD1A gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with HIGD1A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
    2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (2000)
    3. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Epigenetic regulation of gene expression in cervical cancer cells by the tumor microenvironment. (PubMed id 10690527)1, 2 Denko N.C....Giaccia A.J. (2000)
    6. Rcf1 mediates cytochrome oxidase assembly and respirasome formation, revealing heterogeneity of the enzyme complex. (PubMed id 22342701)2 Vukotic M.... Deckers M. (2012)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    9. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (2012)
    10. HIG1, a novel regulator of mitochondrial g-secretase, maintains normal mitochondrial function. (PubMed id 22355194)1 Hayashi H....Kaneda Y. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 25994 HGNC: 29527 AceView: HIG1 Ensembl:ENSG00000181061 euGenes: HUgn25994
    ECgene: HIGD1A H-InvDB: HIGD1A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HIGD1A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HIGD1A gene:
    Search GeneIP for patents involving HIGD1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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