Aliases for HIC2 Gene
Aliases for HIC2 Gene
External Ids for HIC2 Gene
- HGNC: 18595
- Entrez Gene: 23119
- Ensembl: ENSG00000169635
- OMIM: 607712
- UniProtKB: Q96JB3
Previous GeneCards Identifiers for HIC2 Gene
- GC22P018470
- GC22P020096
- GC22P021771
- GC22P004831
- GC22P021452
- GC22P021494
- GC22P021536
- GC22P021836
- GC22P021866
Summaries for HIC2 Gene
GeneCards Summary for HIC2 Gene
HIC2 (HIC ZBTB Transcriptional Repressor 2) is a Protein Coding gene. GO annotations related to this gene include protein C-terminus binding. An important paralog of this gene is HIC1.
UniProtKB/Swiss-Prot for HIC2 Gene
-
Transcriptional repressor.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HIC2 Gene
Genomics for HIC2 Gene
Regulatory Elements for HIC2 Gene
Enhancers for HIC2 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH22G021814 | 2 | FANTOM5 Ensembl ENCODE dbSUPER | 5.4 | +399.9 | 399913 | 6.2 | PKNOX1 ARNT CREB3L1 SIN3A CBX5 ZNF207 FOS KLF13 ZNF263 MCM3 | ENSG00000224086 PPM1F YPEL1 TOP3BP1 MAPK1 HIC2 RNA5SP493 |
| GH22G022036 | 0.9 | ENCODE | 5.4 | +620.4 | 620426 | 1.7 | HDAC1 TBL1XR1 ARNT ZNF76 TCF12 ZNF766 GATA2 ZNF143 FOS CREM | HIC2 IGLVI-70 ENSG00000249333 ENSG00000278657 IGLV10-54 |
| GH22G021864 | 1.7 | FANTOM5 ENCODE dbSUPER | 2.3 | +449.7 | 449721 | 4.3 | HDGF PKNOX1 MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B YY1 | ENSG00000224086 TOP3BP1 MAPK1 SDF2L1 HIC2 RNA5SP493 |
| GH22G021876 | 1.6 | FANTOM5 Ensembl ENCODE dbSUPER | 1.9 | +459.6 | 459581 | 0.9 | BRD4 PKNOX1 USF1 MAX CEBPG BMI1 ARID3A GATA2 NFYB EED | ENSG00000224086 HIC2 MAPK1 ENSG00000225544 |
| GH22G021434 | 0.9 | Ensembl | 0.4 | +18.8 | 18797 | 3.6 | HDGF PKNOX1 TBL1XR1 GATA2 FOS CREM EGR2 HCFC1 USF2 JUNB | LOC105377191 HIC2 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HIC2 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the HIC2 gene promoter:
Regulatory Element Products
Genomic Location for HIC2 Gene
- Chromosome:
- 22
- Start:
- 21,417,404 bp from pter
- End:
- 21,451,463 bp from pter
- Size:
- 34,060 bases
- Orientation:
- Plus strand
Genomic View for HIC2 Gene
Genes around HIC2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q11.21 by Ensembl
- 22q11.21 by Entrez Gene
- 22q11.21 by HGNC
HIC2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HIC2 Gene
Proteins for HIC2 Gene
-
Protein details for HIC2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96JB3-HIC2_HUMAN
- Recommended name:
- Hypermethylated in cancer 2 protein
- Protein Accession:
- Q96JB3
- Q504T6
- Q96KR3
- Q9NSM9
- Q9UPX9
Protein attributes for HIC2 Gene
- Size:
- 615 amino acids
- Molecular mass:
- 66156 Da
- Quaternary structure:
-
- Self-associates. Interacts with HIC1.
- SequenceCaution:
-
- Sequence=BAA82972.2; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for HIC2 Gene
Post-translational modifications for HIC2 Gene
Other Protein References for HIC2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for HIC2
- Invitrogen Antibodies for HIC2
- antibodies-online Antibodies for HIC2: See all 62
- GeneTex HIC2 antibody for HIC2
- GeneTex Pdgfra antibody for HIC2
Protein Products
-
OriGene Purified Proteins for HIC2
- Search Origene for MassSpec and Protein Over-expression Lysates for HIC2
- Origene Custom Protein Services for HIC2
- antibodies-online Proteins for HIC2: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Proteins for HIC2
Assay Products
No data available for DME Specific Peptides for HIC2 Gene
Domains & Families for HIC2 Gene
Gene Families for HIC2 Gene
Protein Domains for HIC2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for HIC2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q96JB3UniProtKB/Swiss-Prot:
HIC2_HUMAN :- Belongs to the krueppel C2H2-type zinc-finger protein family. Hic subfamily.
- Family:
-
- Belongs to the krueppel C2H2-type zinc-finger protein family. Hic subfamily.
Function for HIC2 Gene
Molecular function for HIC2 Gene
- UniProtKB/Swiss-Prot Function:
- Transcriptional repressor.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | NAS | 11554746 |
| GO:0008022 | protein C-terminus binding | IPI | 12052894 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for HIC2 Gene
- MGI mutant phenotypes for HIC2:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for HIC2:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for HIC2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HIC2 gene
- Search ViGene Biosciences for HIC2
CRISPR Products
-
OriGene CRISPR knockouts for HIC2
-
Santa Cruz Biotechnology (SCBT) CRISPR for HIC2
- GenScript: Design CRISPR guide RNA sequences for HIC2
miRNA for HIC2 Gene
- miRTarBase miRNAs that target HIC2
-
- hsa-mir-769-5p (MIRT016094)
- hsa-mir-30b-5p (MIRT023435)
- hsa-mir-24-3p (MIRT030600)
- hsa-mir-28-3p (MIRT038944)
- hsa-mir-484 (MIRT042187)
- hsa-mir-378a-3p (MIRT043900)
- hsa-mir-30a-5p (MIRT087145)
- hsa-mir-30c-5p (MIRT087146)
- hsa-mir-30d-5p (MIRT087147)
- hsa-mir-30e-5p (MIRT087148)
- hsa-mir-577 (MIRT087149)
- hsa-mir-1277-5p (MIRT087151)
- hsa-mir-4495 (MIRT087152)
- hsa-mir-103a-3p (MIRT205324)
- hsa-mir-107 (MIRT205325)
- hsa-mir-153-5p (MIRT205326)
- hsa-mir-491-3p (MIRT205327)
- hsa-mir-1304-5p (MIRT205329)
- hsa-mir-4310 (MIRT205331)
- hsa-mir-7157-5p (MIRT205332)
- hsa-mir-379-5p (MIRT254608)
- hsa-mir-331-3p (MIRT254609)
- hsa-mir-483-5p (MIRT254610)
- hsa-mir-762 (MIRT254611)
- hsa-mir-3927-3p (MIRT254613)
- hsa-mir-4492 (MIRT254615)
- hsa-mir-4498 (MIRT254616)
- hsa-mir-4505 (MIRT254618)
- hsa-mir-3529-5p (MIRT254619)
- hsa-mir-5001-5p (MIRT254623)
- hsa-mir-5787 (MIRT254624)
- hsa-mir-6799-5p (MIRT254627)
- hsa-mir-6825-5p (MIRT254628)
- hsa-mir-6831-5p (MIRT254629)
- hsa-mir-6846-3p (MIRT254630)
- hsa-mir-3150a-3p (MIRT300617)
- hsa-mir-4654 (MIRT300619)
- hsa-mir-4769-5p (MIRT300620)
- hsa-mir-6728-5p (MIRT300621)
- hsa-mir-6756-5p (MIRT300622)
- hsa-mir-6763-5p (MIRT300623)
- hsa-mir-6766-5p (MIRT300624)
- hsa-mir-6776-5p (MIRT300625)
- hsa-mir-21-5p (MIRT300628)
- hsa-mir-590-5p (MIRT300630)
- hsa-mir-95-5p (MIRT300647)
- hsa-mir-6504-3p (MIRT300648)
- hsa-mir-6742-3p (MIRT370475)
- hsa-mir-4483 (MIRT475656)
- hsa-mir-1293 (MIRT475657)
- hsa-mir-6745 (MIRT475658)
- hsa-mir-363-5p (MIRT475659)
- hsa-mir-939-5p (MIRT475660)
- hsa-mir-1343-5p (MIRT475661)
- hsa-mir-3175 (MIRT475662)
- hsa-mir-2861 (MIRT475663)
- hsa-mir-5187-5p (MIRT475664)
- hsa-mir-3649 (MIRT475665)
- hsa-mir-661 (MIRT475666)
- hsa-mir-4435 (MIRT493621)
- hsa-mir-542-3p (MIRT493622)
- hsa-mir-4504 (MIRT493623)
- hsa-mir-504-3p (MIRT493624)
- hsa-mir-8072 (MIRT493625)
- hsa-mir-2277-3p (MIRT493626)
- hsa-mir-3960 (MIRT493627)
- hsa-mir-4680-5p (MIRT493628)
- hsa-mir-4712-5p (MIRT493629)
- hsa-mir-770-5p (MIRT493630)
- hsa-mir-4501 (MIRT493631)
- hsa-mir-4433a-3p (MIRT493632)
- hsa-mir-4700-3p (MIRT493633)
- hsa-mir-8066 (MIRT493634)
- hsa-mir-3924 (MIRT507043)
- hsa-mir-380-3p (MIRT507044)
- hsa-mir-656-3p (MIRT507045)
- hsa-mir-411-3p (MIRT507046)
- hsa-mir-379-3p (MIRT507047)
- hsa-mir-544a (MIRT536883)
- hsa-mir-527 (MIRT536884)
- hsa-mir-518a-5p (MIRT536885)
- hsa-mir-4670-3p (MIRT536886)
- hsa-mir-2276-3p (MIRT536887)
- hsa-mir-6874-3p (MIRT536888)
- hsa-mir-4772-3p (MIRT536889)
- hsa-mir-148b-5p (MIRT536890)
- hsa-mir-148a-5p (MIRT536891)
- hsa-mir-548e-5p (MIRT547982)
- hsa-mir-8067 (MIRT557320)
- hsa-mir-3607-3p (MIRT557321)
- hsa-mir-8055 (MIRT572009)
- hsa-mir-3120-3p (MIRT572010)
- hsa-mir-6789-3p (MIRT572011)
- hsa-mir-6865-5p (MIRT572012)
- hsa-mir-2467-3p (MIRT572013)
- hsa-mir-6815-5p (MIRT572014)
- hsa-mir-1228-3p (MIRT613624)
- hsa-mir-603 (MIRT613625)
- hsa-mir-362-3p (MIRT613626)
- hsa-mir-329-3p (MIRT613627)
- hsa-mir-8485 (MIRT613628)
- hsa-mir-302c-5p (MIRT657428)
- hsa-mir-3143 (MIRT657429)
miRNA Products
- Search ViGene Biosciences for HIC2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HIC2
- Browse OriGene Inhibitory RNA Products For HIC2
-
ViGene Biosciences ready-to-package AAV shRNAs for HIC2 gene
Cell Line Products
-
Horizon Cell Lines for HIC2
-
ViGene Biosciences adenoviral particle packaged cDNA for HIC2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HIC2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HIC2 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HIC2 Gene
Localization for HIC2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HIC2 Gene
- Nucleus.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA,IEA | 11554746 |
Pathways & Interactions for HIC2 Gene
No Data Available
Interacting Proteins for HIC2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0045892 | negative regulation of transcription, DNA-templated | NAS | 11554746 |
No data available for Pathways by source and SIGNOR curated interactions for HIC2 Gene
Transcripts for HIC2 Gene
mRNA/cDNA for HIC2 Gene
- (6) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (154) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HIC2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for HIC2
-
Santa Cruz Biotechnology (SCBT) CRISPR for HIC2
- GenScript: Design CRISPR guide RNA sequences for HIC2
miRNA Products
- Search ViGene Biosciences for HIC2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HIC2
- Browse OriGene Inhibitory RNA Products For HIC2
-
ViGene Biosciences ready-to-package AAV shRNAs for HIC2 gene
Flow Cytometry Products
Expression for HIC2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Ovary (Reproductive System)
- Secondary Oocyte Antral Follicle
-
Gonad
- Secondary Oocyte Antral Follicle
-
Placenta (Extraembryonic Tissues)
This gene is overexpressed in Prostate (62.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for HIC2 Gene
NURSA nuclear receptor signaling pathways regulating expression of HIC2 Gene:
HIC2SOURCE GeneReport for Unigene cluster for HIC2 Gene:
Hs.632767mRNA Expression by UniProt/SwissProt for HIC2 Gene:
Q96JB3-HIC2_HUMAN
Tissue specificity:
Highest levels in cerebellum.
Evidence on tissue expression from TISSUES for HIC2 Gene
- Nervous system(4.1)
Primer Products
-
OriGene qPCR primer pairs for HIC2
-
OriGene qPCR primer pairs and template standards for HIC2
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for HIC2 Gene
Orthologs for HIC2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HIC2 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | HIC2 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Hic2 34 |
|
||
| cow (Bos Taurus) |
Mammalia | HIC2 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Hic2 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | HIC2 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | HIC2 34 35 |
|
||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | hic2 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.14683 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | hic1l 35 |
|
OneToOne | |
| hic2 34 |
|
- Species where no ortholog for HIC2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for HIC2 Gene
Variants for HIC2 Gene
| SNP ID | Clin | Chr 22 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000212880 | -- | 21,420,174(+) | TGCTC(C/T)TGCTG | intron-variant, nc-transcript-variant, upstream-variant-2KB | |
| rs1000282375 | -- | 21,444,849(+) | TCGAG(C/T)CCCAC | intron-variant | |
| rs1000414449 | -- | 21,420,585(+) | GGGTT(A/G)GGGTT | intron-variant, utr-variant-5-prime | |
| rs1000443024 | -- | 21,444,587(+) | ATTTA(C/G)TGTAG | intron-variant | |
| rs1000553688 | -- | 21,425,492(+) | GCCTC(C/T)CGAGT | intron-variant |
Residual Variation Intolerance Score:
17.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.95;
49.24% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HIC2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HIC2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HIC2 Gene
Disorders for HIC2 Gene
Relevant External Links for HIC2
No disorders were found for HIC2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HIC2 Gene
Publications for HIC2 Gene
- Characterization of HRG22, a human homologue of the putative tumor suppressor gene HIC1. (PMID: 11554746) Deltour S. … Leprince D. (Biochem. Biophys. Res. Commun. 2001) 2 3 4 22 64
- Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. (PMID: 19838193) Han J.W. … Zhang X.J. (Nat. Genet. 2009) 3 46 64
- A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins J.E. … Dunham I. (Genome Biol. 2004) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PMID: 12168954) Nakajima D. … Nagase T. (DNA Res. 2002) 3 4 64
Products for HIC2 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Custom Antibody Services
- Browse OriGene ELISA Kits
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- OriGene Purified Proteins for HIC2
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- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HIC2
- Browse OriGene Inhibitory RNA Products For HIC2
- OriGene qPCR primer pairs and template standards for HIC2
- OriGene qPCR primer pairs for HIC2
- OriGene CRISPR knockouts for HIC2
- OriGene ORF clones in human for HIC2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for HIC2 in any vector
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- GenScript Custom overexpressing Cell Line Services for HIC2
- GenScript: Design CRISPR guide RNA sequences for HIC2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Gene Mutant Library, Variants up to 10^11
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- Sino Biological Antibodies
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- Sino Biological Cell Lysates
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for HIC2
- Novus Biologicals proteins and lysates for HIC2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for HIC2: See all 62
- Search antibodies-online for kits
- antibodies-online Proteins for HIC2: See all 5
- Search antibodies-online for peptides
- GeneTex Pdgfra antibody for HIC2
- GeneTex HIC2 antibody for HIC2
- Search GeneTex for Proteins for HIC2
- ViGene Biosciences adenoviral particle packaged cDNA for HIC2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for HIC2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for HIC2 gene
- Search ViGene Biosciences for HIC2
- Horizon Cell Lines for HIC2
- Cyagen custom Knockout/knockin (KOKI) mouse models for HIC2
- VectorBuilder custom plasmid, inducible vectors for HIC2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HIC2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HIC2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
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