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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HIBADH Gene

protein-coding   GIFtS: 53
GCID: GC07M027565

3-hydroxyisobutyrate dehydrogenase

 Explore 5 diseases affiliated with
HIBADH via our new
 Human Malady Compendium 
Biological research products
for HIBADH
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
3-Hydroxyisobutyrate Dehydrogenase1 2
NS5ATP11 2
EC 1.1.1.313 8
3'-Hydroxyisobutyrate Dehydrogenase2
3-Hydroxyisobutyrate Dehydrogenase, Mitochondrial2
EC 1.1.18

External Ids:    HGNC: 49071   Entrez Gene: 111122   Ensembl: ENSG000001060497   OMIM: 6084755   UniProtKB: P319373   

Export aliases for HIBADH gene to outside databases

Previous GC identifers: GC07U990151 GC07M027207 GC07M027273 GC07M027308 GC07M027307 GC07M027338 GC07M027531 GC07M027445


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for HIBADH:
This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role
in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde.
(provided by RefSeq, Nov 2011)

Gene Wiki entry for HIBADH (3-hydroxyisobutyrate dehydrogenase)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007819.17  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HIBADH gene promoter:
         TBP   Max1   MEF-2A   POU2F1   POU2F1b   POU2F1a   FOXO4   aMEF-2   POU2F1c   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): HIBADH promoter sequence
   Search SABiosciences Chromatin IP Primers for HIBADH

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HIBADH


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p15.2   Ensembl cytogenetic band:  7p15.2   HGNC cytogenetic band: 7p15

HIBADH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HIBADH gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M027565:  view genomic region     (about GC identifiers)

Start:
27,565,059 bp from pter      End:
27,702,620 bp from pter
Size:
137,562 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 27,616,251-27,753,745     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: 3HIDH_HUMAN, P31937 (See protein sequence)
Recommended Name: 3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor  
Size: 336 amino acids; 35329 Da
Subunit: Homodimer (By similarity)
Subcellular location: Mitochondrion
2 PDB 3D structures from and Proteopedia for HIBADH:
2GF2 (3D)        2I9P (3D)    
Secondary accessions: Q546Z2 Q9UDN3

Explore the universe of human proteins at neXtProt for HIBADH: NX_P31937

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P31937

  • 4/11 DME Specific Peptides for HIBADH (P31937) (see all 11)
     DAPVSGG  IGLGNMG  SSGRCWSSD  AHQIYRMMC 

    HIBADH Protein expression data from MOPED and PaxDb:    About this image 
    HIBADH Protein Expression
    REFSEQ proteins: NP_689953.1  
    ENSEMBL proteins: 
     ENSP00000265395   ENSP00000393365   ENSP00000390205  
    Reactome Protein details: P31937
    Human Recombinant Protein Products for HIBADH: 
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    Uscn Proteins for HIBADH

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion NAS--
    GO:0005759mitochondrial matrix TAS--

    HIBADH for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    HIBADH for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR006115 6PGDH_NADP-bd
     IPR008927 6-PGluconate_DH_C-like
     IPR015815 HIBADH-type
     IPR011548 IsoBut3OH_DH
     IPR002204 3-OH-isobutyrate_DH-rel_CS

    Graphical View of Domain Structure for InterPro Entry P31937

    ProtoNet protein and cluster: P31937

    2 Blocks protein families:
    IPB002204 3-hydroxyisobutyrate dehydrogenase
    IPB011548 3-hydroxyisobutyrate dehydrogenase


    UniProtKB/Swiss-Prot: 3HIDH_HUMAN, P31937
    Similarity: Belongs to the 3-hydroxyisobutyrate dehydrogenase family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: 3HIDH_HUMAN, P31937
    Catalytic activity: 3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH

         Enzyme Numbers (IUBMB): EC 1.1.1.311 2 EC 1.1.12

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity IEA--
    GO:00084423-hydroxyisobutyrate dehydrogenase activity TAS--
    GO:0051287NAD binding IEA--
         
    HIBADH for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Hibadh (no phenotypes)

    HIBADH for phenotypes           About GeneDecksing

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Branched-chain amino acid catabolism
    Branched-chain amino acid catabolism1.00
    Valine, leucine and isoleucine degradation0.39
    2Metabolism
    Metabolism1.00
    Metabolic pathways0.38
    3Metabolism of amino acids and derivatives
    Metabolism of amino acids and derivatives1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3        Reactome Pathways for HIBADH
        Metabolism
    Metabolism of amino acids and derivatives
    Branched-chain amino acid catabolism


    2         Kegg Pathways  (Kegg details for HIBADH):
        Valine, leucine and isoleucine degradation
    Metabolic pathways

    UniProtKB/Swiss-Prot: 3HIDH_HUMAN, P31937
    Pathway: Amino-acid degradation; L-valine degradation


    HIBADH for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HIBADH

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/14 Interacting proteins for HIBADH (P319373 ENSP000002653954) via UniProtKB, MINT, STRING, and/or I2D (see all 14)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRIM63Q969Q13, ENSP000003633904I2D: score=1 STRING: ENSP00000363390
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    SLC2A4P146723I2D: score=1 
    ABATENSP000002682514STRING: ENSP00000268251
    ALDH1B1ENSP000003669274STRING: ENSP00000366927
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006098pentose-phosphate shunt IEA--
    GO:0006573valine metabolic process ----
    GO:0006574valine catabolic process IDA16466957
    GO:0009083branched-chain amino acid catabolic process TAS--
    GO:0034641cellular nitrogen compound metabolic process TAS--

    HIBADH for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    HIBADH for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for HIBADH

    5 HMDB Compounds for HIBADH    About this table
    CompoundSynonyms CAS #PubMed Ids
    (S)-3-Hydroxyisobutyric acid(S)-3-Hydroxyisobutyric acid (see all 10)2068-83-9--
    (S)-Methylmalonic acid semialdehyde(S)-Methylmalonate semialdehyde (see all 3)99043-16-0--
    2-Methyl-3-oxopropanoic acid2-Methyl-3-oxopropanoate (see all 7)6236-08-4--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--

    1 DrugBank Compound for HIBADH    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    NADHbeta-DPNH (see all 18)606-68-8target--17139284 17016423

    3 Novoseek chemical compound relationships for HIBADH gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    3-hydroxyisobutyrate 98.6 15 16466957 (4), 7527207 (3), 16794601 (1), 20127051 (1) (see all 5)
    methylmalonate semialdehyde 95.3 4 7527207 (3), 2403034 (1)
    valine 53.8 3 7527207 (2), 2403034 (1)

    Search CenterWatch for drugs/clinical trials and news about HIBADH / 3HIDH 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HIBADH gene: 
    NM_152740.3  

    Unigene Cluster for HIBADH:

    3-hydroxyisobutyrate dehydrogenase
    Hs.406758  [show with all ESTs]
    Unigene Representative Sequence: AK025558
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000265395(uc003szf.3 uc003szg.3 uc003szi.3) ENST00000428288
    ENST00000425715 ENST00000496814

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    Additional cDNA sequence: 

    AB050000.1 AF529362.1 AK025558.1 AK311650.1 AK316605.1 BC013855.1 BC020167.1 BC032324.1 

    19 DOTS entries:

    DT.97847807  DT.100815988  DT.100815989  DT.100815981  DT.121046283  DT.92449304  DT.447590  DT.95144324 
    DT.95144346  DT.100803167  DT.40263687  DT.97847808  DT.100683904  DT.100706682  DT.121046302  DT.121046407 
    DT.95144354  DT.121046271  DT.121046314 

    24/403 AceView cDNA sequences (see all 403):

    CR591074 BF933366 BQ130735 AF529362 CD242860 BM725908 CR612191 CB157697 
    AA603638 BI962663 BM781646 BM715305 CN484100 CR600318 BM049491 AI968334 
    W84380 BP368170 AI769986 BQ214426 CR611219 CR608754 BM715336 AW614653 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for HIBADH (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c
    SP1:                                      -                       -                                 
    SP2:                    -                 -                       -                                 
    SP3:                    -     -     -     -                       -                                 
    SP4:                                      -                                                         
    SP5:                                      -     -     -                                             


    ECgene alternative splicing isoforms for HIBADH

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HIBADH expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --
    HIBADH Expression
    About this image
    See HIBADH Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HIBADH

    SOURCE GeneReport for Unigene cluster: Hs.406758

    UniProtKB/Swiss-Prot: 3HIDH_HUMAN, P31937
    Tissue specificity: Detected in skin fibroblasts

        SABiosciences Expression via Pathway-Focused PCR Array including HIBADH: 
              Amino Acid Metabolism II in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for HIBADH gene from 9/34 species (see all 34)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves HIBADH1 3-hydroxyisobutyrate dehydrogenase 80.22(n)
    84.64(a)
      420632  NM_001006362.1  NP_001006362.1 
    lizard
    (Anolis carolinensis)
    Reptilia HIBADH6
    GLYR16
    --
    84(a)
    13(a)
    1 ↔ 1
    possible ortholog
    GL343275.1(1026118-1107736)
    GL343263.1(1308359-1324099)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.37332 Xenopus laevis transcribed sequence with moderate similarity more 79.53(n)    CB209489.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc662622 similar to 3-hydroxyisobutyrate dehydrogenase 79.45(n)   394135  BC055573.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG150931 CG15093 51.87(n)
    48.12(a)
      37166  NM_001202043.1  NP_001188972.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_B0250.51 Protein B0250.5 55.86(n)
    54.95(a)
      180344  NM_075542.5  NP_507943.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G209301 3-hydroxyisobutyrate dehydrogenase 55.79(n)
    51.58(a)
      827841  NM_118211.4  NP_567617.1 
    rice
    (Oryza sativa)
    Liliopsida Os06g06774001 hypothetical protein 55.17(n)
    50.52(a)
      9268115  NM_001188026.1  NP_001174955.1 
    E. coli
    (Escherichia coli)
    Gamma proteobacteria yihU6
    ygbJ6
    gamma-hydroxybutyrate dehydrogenase, NADH-dependen...
    predicted dehydrogenase, with NAD(P)-binding Rossm...
    29(a)
    26(a)
    possible ortholog
    possible ortholog
    Chromosome(4070698-4071594) b3882
    Chromosome(2859452-2860360) b2736


    ENSEMBL Gene Tree for HIBADH (if available)
    TreeFam Gene Tree for HIBADH (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HIBADH gene
    GLYR12  

    HIBADH for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2445 NCBI SNPs in HIBADH are shown (see all 2445    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1505797411,2
    --27564567(+) CTGAAA/CAATAC 1 -- ds50010--------
    rs1387708911,2
    --27564612(+) AGAACA/TTATGC 1 -- ds50010--------
    rs732879281,2
    C--27564643(+) GTGTCT/GTGTTC 1 -- ds50012Minor allele frequency- G:0.05WA 120
    rs1807410011,2
    --27564692(+) TTTTTA/CTCACC 1 -- ds50010--------
    rs1124314821,2
    F--27564698(+) TCACCC/AGTAAA 1 -- ds50012Minor allele frequency- A:0.50CSA 4
    rs132422381,2
    C,F,H--27564744(+) GTCTAG/TGTCTA 1 -- ds500111Minor allele frequency- T:0.31NS EA NA 804
    rs1864650731,2
    --27564757(+) ACCTGA/GAATGT 1 -- ds50010--------
    rs1416931341,2
    --27564779(+) GAGGTA/GGGAAA 1 -- ds50010--------
    rs1462453231,2
    --27564809(+) ATTGGA/GGCATG 1 -- ds50010--------
    rs1913322211,2
    --27564838(+) GAATTA/CCTAGA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for HIBADH (27565059 - 27702620 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for HIBADH: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HIBADH
    DNA2.0 Custom Variant and Variant Library Synthesis for HIBADH

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    HIBADH for disorders           About GeneDecksing

    OMIM gene information: 608475    OMIM disorders: --

    5 diseases for HIBADH:    About MalaCards
    3-hydroxyisobutyric aciduria    maple syrup urine disease    obesity    tuberculosis
    mycobacterium tuberculosis

    Human Genome Epidemiology (HuGE) Navigator: HIBADH (2 documents)

    Export disorders for HIBADH gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HIBADH gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with HIBADH)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Clinical, biochemical, and molecular findings in three patients with 3-hydroxyisobutyric aciduria. (PubMed id 16466957)1, 2, 9 Loupatty F.J....Wanders R.J. (2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    4. Human liver protein map: update 1993. (PubMed id 8313870)1, 2 Hughes G.J.... Hochstrasser D.F. (1993)
    5. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    6. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11112 HGNC: 4907 AceView: HIBADH Ensembl:ENSG00000106049 euGenes: HUgn11112
    ECgene: HIBADH Kegg: 11112 H-InvDB: HIBADH

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HIBADH Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HIBADH gene:
    Search GeneIP for patents involving HIBADH

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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