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Aliases for HIATL2 Gene

Aliases for HIATL2 Gene

  • Hippocampus Abundant Transcript-Like 2 2 3

External Ids for HIATL2 Gene

Previous GeneCards Identifiers for HIATL2 Gene

  • GC09M095088
  • GC09P094216
  • GC09M098748
  • GC09M099708
  • GC09M099663

Summaries for HIATL2 Gene

GeneCards Summary for HIATL2 Gene

HIATL2 (Hippocampus Abundant Transcript-Like 2) is a Protein Coding gene. GO annotations related to this gene include transporter activity. An important paralog of this gene is HIATL1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HIATL2 Gene

Genomics for HIATL2 Gene

Regulatory Elements for HIATL2 Gene

Genomic Location for HIATL2 Gene

96,898,066 bp from pter
97,013,580 bp from pter
115,515 bases
Minus strand

Genomic View for HIATL2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for HIATL2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HIATL2 Gene

Proteins for HIATL2 Gene

  • Protein details for HIATL2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Hippocampus abundant transcript-like protein 2
    Protein Accession:
    Secondary Accessions:
    • Q9BSG7

    Protein attributes for HIATL2 Gene

    134 amino acids
    Molecular mass:
    14477 Da
    Quaternary structure:
    No Data Available
    • Sequence=BC005058; Type=Miscellaneous discrepancy; Note=The sequence differs at the 3 end.; Evidence={ECO:0000305};

neXtProt entry for HIATL2 Gene

Proteomics data for HIATL2 Gene at MOPED

Post-translational modifications for HIATL2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for HIATL2 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for HIATL2 Gene

Domains for HIATL2 Gene

Protein Domains for HIATL2 Gene


Suggested Antigen Peptide Sequences for HIATL2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the major facilitator superfamily.
  • Belongs to the major facilitator superfamily.
genes like me logo Genes that share domains with HIATL2: view

No data available for Gene Families for HIATL2 Gene

Function for HIATL2 Gene

Gene Ontology (GO) - Molecular Function for HIATL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005215 transporter activity IEA --
genes like me logo Genes that share ontologies with HIATL2: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for HIATL2

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HIATL2 Gene

Localization for HIATL2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for HIATL2 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for HIATL2 Gene COMPARTMENTS Subcellular localization image for HIATL2 gene
Compartment Confidence
cytosol 2
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for HIATL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with HIATL2: view

Pathways for HIATL2 Gene

SuperPathways for HIATL2 Gene

No Data Available

Interacting Proteins for HIATL2 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000364371 for HIATL2 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for HIATL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with HIATL2: view

No data available for Pathways by source for HIATL2 Gene

Transcripts for HIATL2 Gene

mRNA/cDNA for HIATL2 Gene

Unigene Clusters for HIATL2 Gene

Hippocampus abundant transcript-like 2:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for HIATL2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for HIATL2 Gene

No ASD Table

Relevant External Links for HIATL2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for HIATL2 Gene

mRNA expression in normal human tissues for HIATL2 Gene

SOURCE GeneReport for Unigene cluster for HIATL2 Gene Hs.610084

genes like me logo Genes that share expressions with HIATL2: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for HIATL2 Gene

Orthologs for HIATL2 Gene

This gene was present in the common ancestor of animals.

Orthologs for HIATL2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia HIATL1 36
  • 23 (a)
(Canis familiaris)
Mammalia -- 36
  • 24 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 19 (a)
(Mus musculus)
Mammalia Hiatl1 36
  • 21 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
(Pan troglodytes)
Mammalia HIATL2 36
  • 96 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 19 (a)
(Danio rerio)
Actinopterygii CU856539.1 36
  • 17 (a)
si:ch211-87m7.2 36
  • 17 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG11537 36
  • 10 (a)
CG17637 36
  • 9 (a)
CG18281 36
  • 8 (a)
CG5078 36
  • 14 (a)
(Caenorhabditis elegans)
Secernentea T25D3.4 36
  • 13 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6723 36
  • 15 (a)
Species with no ortholog for HIATL2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for HIATL2 Gene

Gene Tree for HIATL2 (if available)
Gene Tree for HIATL2 (if available)

Paralogs for HIATL2 Gene

Paralogs for HIATL2 Gene

(2) SIMAP similar genes for HIATL2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with HIATL2: view

Variants for HIATL2 Gene

Sequence variations from dbSNP and Humsavar for HIATL2 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs963957 -- 96,976,429(+) aacct(A/G)ggagg intron-variant
rs1410189 -- 96,985,374(+) atata(G/T)tggac intron-variant
rs1410190 -- 96,985,532(+) aacaa(A/C)ccaat intron-variant
rs2013508 -- 96,972,299(-) atgct(C/T)gctcg intron-variant
rs2246756 -- 96,979,670(+) ACTCT(C/T)TGAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for HIATL2 Gene

Variant ID Type Subtype PubMed ID
nsv520001 CNV Loss 19592680
nsv831661 CNV Loss 17160897
esv2738813 CNV Deletion 23290073
nsv893606 CNV Gain 21882294
nsv6625 CNV Insertion 18451855
nsv831662 CNV Gain 17160897

Relevant External Links for HIATL2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HIATL2 Gene

Disorders for HIATL2 Gene

No disorders were found for HIATL2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for HIATL2 Gene

Publications for HIATL2 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3

Products for HIATL2 Gene

Sources for HIATL2 Gene

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