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Aliases for HIAT1 Gene

Aliases for HIAT1 Gene

  • Hippocampus Abundant Transcript 1 2 3
  • Putative Tetracycline Transporter-Like Protein 4

External Ids for HIAT1 Gene

Previous GeneCards Identifiers for HIAT1 Gene

  • GC01P101294
  • GC01P099684
  • GC01P099794
  • GC01P099966
  • GC01P100215
  • GC01P100276
  • GC01P100503
  • GC01P098626

Summaries for HIAT1 Gene

GeneCards Summary for HIAT1 Gene

HIAT1 (Hippocampus Abundant Transcript 1) is a Protein Coding gene. GO annotations related to this gene include transporter activity. An important paralog of this gene is HIATL1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HIAT1 Gene

Genomics for HIAT1 Gene

Regulatory Elements for HIAT1 Gene

Genomic Location for HIAT1 Gene

Start:
100,038,097 bp from pter
End:
100,083,377 bp from pter
Size:
45,281 bases
Orientation:
Plus strand

Genomic View for HIAT1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for HIAT1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HIAT1 Gene

Proteins for HIAT1 Gene

  • Protein details for HIAT1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96MC6-HIAT1_HUMAN
    Recommended name:
    Hippocampus abundant transcript 1 protein
    Protein Accession:
    Q96MC6
    Secondary Accessions:
    • Q6P2N7
    • Q8N8K2
    • Q8NBV3
    • Q96NY0
    • Q9NT25

    Protein attributes for HIAT1 Gene

    Size:
    490 amino acids
    Molecular mass:
    53027 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC04836.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAC11473.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for HIAT1 Gene

Proteomics data for HIAT1 Gene at MOPED

Post-translational modifications for HIAT1 Gene

  • Glycosylation at Asn12 and Asn453
  • Modification sites at PhosphoSitePlus

Other Protein References for HIAT1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for HIAT1 Gene

Domains for HIAT1 Gene

Protein Domains for HIAT1 Gene

Suggested Antigen Peptide Sequences for HIAT1 Gene

Graphical View of Domain Structure for InterPro Entry

Q96MC6

UniProtKB/Swiss-Prot:

HIAT1_HUMAN :
  • Q96MC6
Family:
  • Belongs to the major facilitator superfamily.
genes like me logo Genes that share domains with HIAT1: view

No data available for Gene Families for HIAT1 Gene

Function for HIAT1 Gene

Gene Ontology (GO) - Molecular Function for HIAT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005215 transporter activity IEA --
genes like me logo Genes that share ontologies with HIAT1: view

miRNA for HIAT1 Gene

miRTarBase miRNAs that target HIAT1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for HIAT1 Gene

Localization for HIAT1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for HIAT1 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for HIAT1 Gene COMPARTMENTS Subcellular localization image for HIAT1 gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for HIAT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with HIAT1: view

Pathways for HIAT1 Gene

SuperPathways for HIAT1 Gene

No Data Available

Interacting Proteins for HIAT1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000359171%0d%0a9606.ENSP00000385269%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000359171 for HIAT1 Gene via STRING

Gene Ontology (GO) - Biological Process for HIAT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with HIAT1: view

No data available for Pathways by source for HIAT1 Gene

Transcripts for HIAT1 Gene

mRNA/cDNA for HIAT1 Gene

Unigene Clusters for HIAT1 Gene

Hippocampus abundant transcript 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HIAT1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b · 12c
SP1: - -
SP2: - -
SP3:
SP4:

Relevant External Links for HIAT1 Gene

GeneLoc Exon Structure for
HIAT1
ECgene alternative splicing isoforms for
HIAT1

Expression for HIAT1 Gene

mRNA expression in normal human tissues for HIAT1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for HIAT1 Gene

SOURCE GeneReport for Unigene cluster for HIAT1 Gene Hs.124156

genes like me logo Genes that share expressions with HIAT1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for HIAT1 Gene

Orthologs for HIAT1 Gene

This gene was present in the common ancestor of animals.

Orthologs for HIAT1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia HIAT1 35
  • 99.93 (n)
  • 100 (a)
HIAT1 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia HIAT1 35
  • 94.69 (n)
  • 99.59 (a)
HIAT1 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia HIAT1 35
  • 93.8 (n)
  • 99.57 (a)
HIAT1 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Hiat1 35
  • 92.24 (n)
  • 99.8 (a)
Hiat1 16
Hiat1 36
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia HIAT1 36
  • 96 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia HIAT1 36
  • 93 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Hiat1 35
  • 92.45 (n)
  • 99.39 (a)
chicken
(Gallus gallus)
Aves HIAT1 36
  • 84 (a)
OneToOne
LOC428335 35
  • 71.86 (n)
  • 81.56 (a)
lizard
(Anolis carolinensis)
Reptilia HIAT1 36
  • 95 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia hiat1-A-prov 35
tropical clawed frog
(Silurana tropicalis)
Amphibia hiat1 35
  • 78.71 (n)
  • 93.43 (a)
Str.8911 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.869 35
zebrafish
(Danio rerio)
Actinopterygii hiat1a 35
  • 72.04 (n)
  • 82.86 (a)
hiat1b 36
  • 86 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG11537 36
  • 39 (a)
ManyToMany
CG17637 36
  • 32 (a)
ManyToMany
CG18281 36
  • 30 (a)
ManyToMany
CG5078 36
  • 48 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea T25D3.4 36
  • 47 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6723 36
  • 56 (a)
OneToMany
Species with no ortholog for HIAT1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for HIAT1 Gene

ENSEMBL:
Gene Tree for HIAT1 (if available)
TreeFam:
Gene Tree for HIAT1 (if available)

Paralogs for HIAT1 Gene

Paralogs for HIAT1 Gene

Selected SIMAP similar genes for HIAT1 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with HIAT1: view

Variants for HIAT1 Gene

Sequence variations from dbSNP and Humsavar for HIAT1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs5876 -- 100,082,438(+) TTTCT(C/T)GCCAC utr-variant-3-prime
rs483217 -- 100,064,612(-) aattt(A/C)tatga intron-variant
rs485619 -- 100,051,354(-) GAGGG(C/T)AGTGG intron-variant
rs487805 -- 100,064,125(-) acaca(C/T)acata intron-variant
rs488745 -- 100,064,037(-) AGAGG(C/G)ACCCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for HIAT1 Gene

Variant ID Type Subtype PubMed ID
nsv830804 CNV Gain 17160897

Relevant External Links for HIAT1 Gene

HapMap Linkage Disequilibrium report
HIAT1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HIAT1 Gene

Disorders for HIAT1 Gene

Relevant External Links for HIAT1

Genetic Association Database (GAD)
HIAT1
genes like me logo Genes that share disorders with HIAT1: view

No data available for UniProtKB/Swiss-Prot for HIAT1 Gene

Publications for HIAT1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Cloning of a cDNA encoding a novel sugar transporter expressed in the neonatal mouse hippocampus. (PMID: 9299464) Matsuo N. … Okubo K. (Biochem. Biophys. Res. Commun. 1997) 2 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PMID: 16303743) Otsuki T. … Isogai T. (DNA Res. 2005) 3

Products for HIAT1 Gene

Sources for HIAT1 Gene

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