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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HHIPL2 Gene

protein-coding   GIFtS: 49
GCID: GC01M222695

HHIP-Like 2

(Previous name: KIAA1822-like)
(Previous symbol: KIAA1822L)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
HHIP-Like 21 2
KIAA1822L1 2 3
KIAA1822-like1
Hedgehog Interacting Protein-Like 22
HHIP-Like Protein 22
HHIP33

External Ids:    HGNC: 258421   Entrez Gene: 798022   Ensembl: ENSG000001435127   UniProtKB: Q6UWX43   

Export aliases for HHIPL2 gene to outside databases

Previous GC identifers: GC01M220763 GC01M193369


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for HHIPL2 Gene: 
HHIPL2 (HHIP-like 2) is a protein-coding gene. Diseases associated with HHIPL2 include thyroiditis. GO annotations related to this gene include quinone binding and oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor. An important paralog of this gene is HHIP.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_167186.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HHIPL2 gene promoter:
         MyoD   HSF1 (long)   NF-kappaB   HNF-1A   PPAR-alpha   HNF-1   Zic1   HSF1short   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHHIPL2 promoter sequence
   Search SABiosciences Chromatin IP Primers for HHIPL2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HHIPL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q41   Ensembl cytogenetic band:  1q41   HGNC cytogenetic band: 1q41

HHIPL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HHIPL2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M222695:  view genomic region     (about GC identifiers)

Start:
222,695,602 bp from pter      End:
222,721,445 bp from pter
Size:
25,844 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HIPL2_HUMAN, Q6UWX4 (See protein sequence)
Recommended Name: HHIP-like protein 2 precursor  
Size: 724 amino acids; 80779 Da
Subcellular location: Secreted (Potential)
Sequence caution: Sequence=AAH15201.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAH15201.1; Type=Erroneous termination; Positions=452; Note=Translated as Glu; Sequence=AAH15201.1;
Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence; Sequence=AAH16552.1;
Type=Erroneous initiation; Sequence=BAB14717.1; Type=Erroneous initiation;
Secondary accessions: Q6GU65 Q96BT4 Q96BU5 Q9H8A0

Explore the universe of human proteins at neXtProt for HHIPL2: NX_Q6UWX4

Explore proteomics data for HHIPL2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6UWX4

  • HHIPL2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HHIPL2 Protein Expression
    REFSEQ proteins: NP_079022.2  
    ENSEMBL proteins: 
     ENSP00000342118  

    Human Recombinant Protein Products for HHIPL2: 
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    OriGene Protein Over-expression Lysate for HHIPL2
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for HHIPL2
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for HHIPL2 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    HHIPL2 for ontologies           About GeneDecksing



    HHIPL2 Antibody Products: 
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    Assay Products for HHIPL2: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for HHIPL2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for HHIPL2 
    Cloud-Clone Corp. CLIAs for HHIPL2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR012938 Glc/Sorbosone_DH
     IPR018143 Folate_rcpt-like
     IPR011041 Quinoprot_gluc/sorb_DH
     IPR011042 6-blade_b-propeller_TolB-like

    Graphical View of Domain Structure for InterPro Entry Q6UWX4

    ProtoNet protein and cluster: Q6UWX4

    UniProtKB/Swiss-Prot: HIPL2_HUMAN, Q6UWX4
    Similarity: Belongs to the HHIP family


    HHIPL2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0016901oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor IEA--
    GO:0048038quinone binding IEA--
         
    HHIPL2 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for HHIPL2:
     G0/1 arrest  Increased G1 DNA content  Increased gamma-H2AX phosphory 

         1 MGI phenotypic allele for Hhipl2 (no phenotypes)

    HHIPL2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Hhipl2tm1Lex for HHIPL2

       inGenious Targeting Laboratory - Custom generated mouse model solutions for HHIPL2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for HHIPL2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HHIPL2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HHIPL2 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HHIPL2
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate HHIPL2
    SwitchGear 3'UTR luciferase reporter plasmidHHIPL2 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for HHIPL2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HHIPL2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for HHIPL2
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    Clone
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    OriGene clones in human, mouse for HHIPL2 (see all 5)
    OriGene ORF clones in mouse, rat for HHIPL2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HHIPL2 (NM_024746)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HHIPL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HHIPL2
    Sirion Biotech Customized lentivirus for stable overexpression of HHIPL2 
                         Customized lentivirus expression plasmids for stable overexpression of HHIPL2 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for HHIPL2
    Search LifeMap BioReagents cell lines for HHIPL2
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HHIPL2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HHIPL2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

    5/23 Interacting proteins for HHIPL2 (ENSP000003421184) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000206500ENSP000003731064STRING: ENSP00000373106
    ARTNENSP000003919984STRING: ENSP00000391998
    CACHD1ENSP000002900394STRING: ENSP00000290039
    CERS2ENSP000002716884STRING: ENSP00000271688
    ECM1ENSP000003580434STRING: ENSP00000358043
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process IEA--

    HHIPL2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HHIPL2 (HIPL2)

    Search CenterWatch for drugs/clinical trials and news about HHIPL2 / HIPL2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HHIPL2 gene: 
    NM_024746.3  

    Unigene Cluster for HHIPL2:

    HHIP-like 2
    Hs.665660  [show with all ESTs]
    Unigene Representative Sequence: BC007638
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000473144 ENST00000343410(uc001hnh.1) ENST00000468172 ENST00000494899

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HHIPL2
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate HHIPL2
    SwitchGear 3'UTR luciferase reporter plasmidHHIPL2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for HHIPL2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HHIPL2
    Clone
    Products:
         
    OriGene clones in human, mouse for HHIPL2 (see all 5)
    OriGene ORF clones in mouse, rat for HHIPL2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HHIPL2 (NM_024746)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HHIPL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HHIPL2
    Sirion Biotech Customized lentivirus for stable overexpression of HHIPL2 
                         Customized lentivirus expression plasmids for stable overexpression of HHIPL2 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for HHIPL2
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat HHIPL2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HHIPL2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HHIPL2

    Additional mRNA sequence: 

    AK023902.1 AY358602.1 BC007638.1 BC015167.1 BC015201.1 BC016552.1 

    2 DOTS entries:

    DT.40125464  DT.92369219 

    16 AceView cDNA sequences:

    BQ433070 AA884860 BC015167 AU141539 CB157962 BX089001 BQ447786 BE878716 
    CB157610 BU186234 BE909936 AA812932 AU159074 BI000332 BE072810 BG949302 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for HHIPL2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b · 11c
    SP1:                                -     -                             -                           
    SP2:                                                                    -                           
    SP3:                                      -                                                         
    SP4:                                                                                                


    ECgene alternative splicing isoforms for HHIPL2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HHIPL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCCTGCTTG
    HHIPL2 Expression
    About this image


    See HHIPL2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HHIPL2

    SOURCE GeneReport for Unigene cluster: Hs.665660
        SABiosciences Custom PCR Arrays for HHIPL2
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HHIPL2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HHIPL2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for HHIPL2 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hhipl21 , 5 hedgehog interacting protein-like 21, 5 84.73(n)1
    84.64(a)1
      15
    787721  NM_030175.41  NP_084451.21 
     1834185035 
    chicken
    (Gallus gallus)
    Aves HHIPL21 HHIP-like 2 70.35(n)
    70.85(a)
      421339  XM_419401.3  XP_419401.1 
    lizard
    (Anolis carolinensis)
    Reptilia HHIPL26
    Uncharacterized protein
    65(a)
    1 ↔ 1
    1(244356181-244385967)
    African clawed frog
    (Xenopus laevis)
    Amphibia tthu-A-prov2 tail-specific thyroid hormone up-regulated (gene 5) 74.39(n)    U37373.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5603761 HHIP-like protein 2-like 62(n)
    63(a)
      560376  XM_683781.2  XP_688873.2 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G399701 hypothetical protein 43.63(n)
    35.71(a)
      833994  NM_123360.4  NP_198813.3 


    ENSEMBL Gene Tree for HHIPL2 (if available)
    TreeFam Gene Tree for HHIPL2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HHIPL2 gene
    HHIP2  HHIPL12  
    2 SIMAP similar genes for HHIPL2 using alignment to 1 protein entry:     HIPL2_HUMAN:
    HHIPL1    HHIP

    HHIPL2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/680 SNPs in HHIPL2 are shown (see all 680)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs114878511,2
    C,F--222695209(+) AAACTC/TCAGCC 1 -- int11Minor allele frequency- T:0.08WA 118
    rs1811481251,2
    --222695274(+) AGGCTC/GTGTGT 1 -- int10--------
    rs1870746031,2
    --222695288(+) TTAAAC/TTCTTT 1 -- int10--------
    rs1915596581,2
    --222695304(+) CTGCAA/GTACTG 1 -- int10--------
    rs668803101,2
    C,F--222695314(+) GTGGTC/ATCAGT 1 -- int14Minor allele frequency- A:0.13WA NA 242
    rs1413622611,2
    C--222695726(+) ACCAGC/TAATCT 1 -- ut310--------
    rs1841971281,2
    --222695824(+) ACCGCC/TCTGCC 1 -- ut310--------
    rs1870044371,2
    --222695829(+) CCTGCC/TCCACC 1 -- ut310--------
    rs3754499291,2
    C--222695924(+) CTGTCA/GGCCAC 1 -- ut310--------
    rs617393711,2
    C,F--222696004(+) TGTGGC/ATTTTC 2 /S /I mis15Minor allele frequency- A:0.02NS WA NA EU 5991

    HapMap Linkage Disequilibrium report for HHIPL2 (222695602 - 222721445 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for HHIPL2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv873205CNV Loss21882294
    nsv873203CNV Gain21882294


    Human Gene Mutation Database (HGMD): HHIPL2
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing HHIPL2
    DNA2.0 Custom Variant and Variant Library Synthesis for HHIPL2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for HHIPL2:    About MalaCards
    thyroiditis    


    HHIPL2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): HHIPL2
    Human Genome Epidemiology (HuGE) Navigator: HHIPL2 (1 document)

    Export disorders for HHIPL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HHIPL2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with HHIPL2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (2003)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Iron excess limits HHIPL-2 gene expression and decreas es osteoblastic activity in human MG-63 cells. (PubMed id 22237814)1 Doyard M....Guggenbuhl P. (2012)
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    6. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
    7. Comparative genomics on HHIP family orthologs. (PubMed id 16391842)2 Katoh Y. and Katoh M. (2006)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79802 HGNC: 25842 AceView: FLJ13840.1 Ensembl:ENSG00000143512 euGenes: HUgn79802
    ECgene: HHIPL2 H-InvDB: HHIPL2

    (According to HUGE)
    About This Section
    HUGE: KIAA1822L KIAA1822-like

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HHIPL2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HHIPL2 gene:
    Search GeneIP for patents involving HHIPL2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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