Aliases for HHAT Gene
External Ids for HHAT Gene
'Skinny hedgehog' (SKI1) encodes an enzyme that acts within the secretory pathway to catalyze amino-terminal palmitoylation of 'hedgehog' (see MIM 600725).[supplied by OMIM, Jul 2002]
GeneCards Summary for HHAT Gene
HHAT (Hedgehog Acyltransferase) is a Protein Coding gene. Diseases associated with HHAT include chondrodysplasia - disorder of sex development and melanoma. Among its related pathways are Signaling events mediated by the Hedgehog family. GO annotations related to this gene include GTP binding and palmitoyltransferase activity. An important paralog of this gene is HHATL.
UniProtKB/Swiss-Prot for HHAT Gene
Catalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling (By similarity). May bind GTP.