Aliases for HHAT Gene
Aliases for HHAT Gene
External Ids for HHAT Gene
- HGNC: 18270
- Entrez Gene: 55733
- Ensembl: ENSG00000054392
- OMIM: 605743
- UniProtKB: Q5VTY9
Previous GeneCards Identifiers for HHAT Gene
- GC01P206890
- GC01P208568
- GC01P210501
- GC01P181175
Summaries for HHAT Gene
-
'Skinny hedgehog' (SKI1) encodes an enzyme that acts within the secretory pathway to catalyze amino-terminal palmitoylation of 'hedgehog' (see MIM 600725).[supplied by OMIM, Jul 2002]
GeneCards Summary for HHAT Gene
HHAT (Hedgehog Acyltransferase) is a Protein Coding gene. Diseases associated with HHAT include Chondrodysplasia-Pseudohermaphroditism Syndrome and Thoracic Outlet Syndrome. Among its related pathways are Signaling by Hedgehog and Signaling by GPCR. GO annotations related to this gene include GTP binding and palmitoyltransferase activity. An important paralog of this gene is HHATL.
UniProtKB/Swiss-Prot for HHAT Gene
-
Catalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling. May bind GTP.
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HHAT Gene
Genomics for HHAT Gene
Regulatory Elements for HHAT Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH01G210236 | 1.2 | Ensembl ENCODE | 11.2 | -90.9 | -90900 | 2.2 | PKNOX1 ATF1 ZNF133 SIN3A FEZF1 ZNF2 ZNF121 GLIS2 KLF7 TSHZ1 | HHAT SERTAD4-AS1 GC01P210243 |
| GH01G211256 | 1.2 | ENCODE | 11 | +930.9 | 930897 | 5.1 | MLX CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YY1 ZNF143 ZNF263 SP3 | LINC00467 HHAT RCOR3 LOC105372902 |
| GH01G210331 | 1.2 | FANTOM5 ENCODE | 10 | +4.4 | 4424 | 1.7 | PKNOX1 TBL1XR1 SCRT2 FOS ETV6 RELB IKZF2 CREM SP3 CBFB | SERTAD4-AS1 HHAT SERTAD4 PIR50724 |
| GH01G210342 | 1.2 | Ensembl ENCODE | 8.7 | +15.3 | 15337 | 1.2 | HDGF PKNOX1 BMI1 YBX1 ZNF2 ZNF366 RELB IKZF2 EGR2 REST | SERTAD4-AS1 RNU5A-8P SERTAD4 HHAT PIR50724 |
| GH01G210328 | 1 | ENCODE | 7.4 | +0.7 | 694 | 1.8 | HDGF WRNIP1 ZNF133 SIN3A DMAP1 YY1 ZNF121 GLIS2 ELK1 ZNF143 | SERTAD4-AS1 RCOR3 SERTAD4 HHAT PIR50724 |
- Transcription factor binding sites by QIAGEN in the HHAT gene promoter:
Regulatory Element Products
Genomic Location for HHAT Gene
- Chromosome:
- 1
- Start:
- 210,328,252 bp from pter
- End:
- 210,676,298 bp from pter
- Size:
- 348,047 bases
- Orientation:
- Plus strand
Genomic View for HHAT Gene
- Cytogenetic band:
-
- 1q32.2 by Ensembl
- 1q32.2 by Entrez Gene
- 1q32.2 by HGNC
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HHAT Gene
Proteins for HHAT Gene
-
Protein details for HHAT Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5VTY9-HHAT_HUMAN
- Recommended name:
- Protein-cysteine N-palmitoyltransferase HHAT
- Protein Accession:
- Q5VTY9
- B7Z4D5
- B7Z5I1
- B7Z868
- B7ZA75
- D3DT91
- F5H444
- Q17RZ7
- Q4G0K3
- Q5CZ95
- Q5TGI2
- Q9NVH9
- Q9Y3N8
Protein attributes for HHAT Gene
- Size:
- 493 amino acids
- Molecular mass:
- 57313 Da
- Quaternary structure:
- No Data Available
Protein Expression for HHAT Gene
Post-translational modifications for HHAT Gene
Other Protein References for HHAT Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- NP_001116306.1
- NP_001164035.1
- NP_001164051.1
- NP_001164058.1
- NP_001164059.1
- NP_060664.2
- XP_006711504.1
- XP_011508039.1
- XP_011508040.1
- XP_011508041.1
- XP_011508042.1
- XP_011508043.1
- XP_011508044.1
- XP_011508046.1
- XP_011508048.1
- XP_011508049.1
- XP_016857215.1
- XP_016857216.1
- XP_016857217.1
- XP_016857218.1
- XP_016857219.1
- XP_016857220.1
- XP_016857221.1
- XP_016857222.1
- XP_016857223.1
- XP_016857224.1
- XP_016857225.1
- XP_016857226.1
- XP_016857227.1
- XP_016857228.1
- XP_016857229.1
- XP_016857230.1
- XP_016857231.1
- XP_016857232.1
- XP_016857233.1
Antibody Products
-
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- Novus Biologicals Antibodies for HHAT
-
Abcam antibodies for HHAT
- Invitrogen Antibodies for HHAT
- antibodies-online Antibodies for HHAT: See all 35
- GeneTex HHAT antibody for HHAT
Protein Products
-
OriGene Purified Proteins for HHAT
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-
Abcam proteins for HHAT
Assay Products
- antibodies-online Kits for HHAT: See all 2
No data available for DME Specific Peptides for HHAT Gene
Domains & Families for HHAT Gene
Gene Families for HHAT Gene
Suggested Antigen Peptide Sequences for HHAT Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ34867 fis, clone NT2NE2014176, highly similar to Protein-cysteine N-palmitoyltransferase HHAT (EC 2.3.1.-) (B1AK61_HUMAN)
- cDNA FLJ53989, highly similar to Protein-cysteine N-palmitoyltransferase HHAT (EC 2.3.1.-) (B7Z2U8_HUMAN)
- cDNA FLJ59340, highly similar to Protein-cysteine N-palmitoyltransferase HHAT (EC 2.3.1.-) (B7Z4D5_HUMAN)
- cDNA, FLJ79423, highly similar to Protein-cysteine N-palmitoyltransferase HHAT(EC 2.3.1.-) (B7Z5I1_HUMAN)
- Skinny hedgehog protein 1 (HHAT_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q5VTY9UniProtKB/Swiss-Prot:
HHAT_HUMAN :- Belongs to the membrane-bound acyltransferase family. HHAT subfamily.
- Family:
-
- Belongs to the membrane-bound acyltransferase family. HHAT subfamily.
Function for HHAT Gene
Molecular function for HHAT Gene
- UniProtKB/Swiss-Prot Function:
- Catalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling. May bind GTP.
Enzyme Numbers (IUBMB) for HHAT Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005525 | GTP binding | IEA | -- |
| GO:0008374 | O-acyltransferase activity | TAS | -- |
| GO:0016409 | palmitoyltransferase activity | IEA | -- |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0016746 | transferase activity, transferring acyl groups | IEA | -- |
Phenotypes for HHAT Gene
- MGI mutant phenotypes for HHAT:
-
inferred from 3 alleles
- mortality/aging
- growth/size/body region phenotype
- nervous system phenotype
- homeostasis/metabolism phenotype
- cardiovascular system phenotype
- respiratory system phenotype
- digestive/alimentary phenotype
- reproductive system phenotype
- endocrine/exocrine gland phenotype
- vision/eye phenotype
- limbs/digits/tail phenotype
- skeleton phenotype
- embryo phenotype
- craniofacial phenotype
- GenomeRNAi human phenotypes for HHAT:
Animal Model Products
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-
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CRISPR Products
-
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-
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miRNA for HHAT Gene
- miRTarBase miRNAs that target HHAT
-
- hsa-mir-193b-3p (MIRT016338)
- hsa-mir-122-5p (MIRT023266)
- hsa-mir-10b-5p (MIRT439127)
- hsa-let-7c-5p (MIRT439160)
- hsa-mir-6818-3p (MIRT623701)
- hsa-mir-6873-3p (MIRT623702)
- hsa-mir-593-3p (MIRT623703)
- hsa-mir-6895-3p (MIRT623704)
- hsa-mir-6817-3p (MIRT623705)
- hsa-mir-7110-3p (MIRT623706)
- hsa-mir-6845-3p (MIRT623707)
- hsa-mir-3189-5p (MIRT637006)
- hsa-mir-7160-5p (MIRT657442)
- hsa-mir-8077 (MIRT657443)
- hsa-mir-4663 (MIRT657444)
- hsa-mir-93-3p (MIRT657445)
miRNA Products
- Search ViGene Biosciences for HHAT
Inhibitory RNA Products
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-
ViGene Biosciences ready-to-package AAV shRNAs for HHAT gene
Clone Products
-
GenScript: Next-day shipping cDNA ORF clone for HHAT in any vector
- NM_018194
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- XM_006711441
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- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
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Cell Line Products
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-
ViGene Biosciences adenoviral particle packaged cDNA for HHAT gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HHAT gene
-
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Flow Cytometry Products
No data available for Transcription Factor Targets and HOMER Transcription for HHAT Gene
Localization for HHAT Gene
Subcellular locations from UniProtKB/Swiss-Prot for HHAT Gene
- Endoplasmic reticulum membrane; Multi-pass membrane protein.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005783 | endoplasmic reticulum | IEA | -- |
| GO:0005789 | endoplasmic reticulum membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for HHAT Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | CDK-mediated phosphorylation and removal of Cdc6 | ||
| 2 | Signaling by GPCR | ||
| 3 | Signaling by Hedgehog | ||
| 4 | Signaling events mediated by the Hedgehog family | ||
Pathways by source for HHAT Gene
1 BioSystems pathway for HHAT Gene
3 Reactome pathways for HHAT Gene
Interacting Proteins for HHAT Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007224 | smoothened signaling pathway | IEA | -- |
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0018345 | protein palmitoylation | IEA | -- |
| GO:1903955 | positive regulation of protein targeting to mitochondrion | IMP | 24270810 |
Drugs & Compounds for HHAT Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Guanosine triphosphate | Experimental | Pharma | 0 | |||
| GANT61 | Pharma | GLI antagonist, GLI antagonist; inhibits Hedgehog (Hh) signaling | 0 | |||
| LY2940680 | Pharma | Hedgehog/SMO antagonist,inhibits Hh signaling | 0 | |||
| PF-5274857 | Pharma | Smo antagonist,potent and selective | 0 | |||
| SANT-1 | Pharma | Shh inhibitor,potent and cell-permeable, Inhibitor of hedgehog (Hh) signaling; antagonizes smoothened activity | 0 |
(4) ApexBio Compounds for HHAT Gene
| Compound | Action | Cas Number |
|---|---|---|
| GANT61 | GLI antagonist | 500579-04-4 |
| LY2940680 | Hedgehog/SMO antagonist,inhibits Hh signaling | 1258861-20-9 |
| PF-5274857 | Smo antagonist,potent and selective | 1373615-35-0 |
| SANT-1 | Shh inhibitor,potent and cell-permeable | 304909-07-7 |
Drug Products
- ApexBio compounds for HHAT
Transcripts for HHAT Gene
mRNA/cDNA for HHAT Gene
- (35) REFSEQ mRNAs :
- (14) Additional mRNA sequences :
- (44) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HHAT Gene
CRISPR Products
-
OriGene CRISPR knockouts for HHAT
-
Santa Cruz Biotechnology (SCBT) CRISPR for HHAT
- GenScript: Design CRISPR guide RNA sequences for HHAT
miRNA Products
- Search ViGene Biosciences for HHAT
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HHAT
- Browse OriGene Inhibitory RNA Products For HHAT
-
ViGene Biosciences ready-to-package AAV shRNAs for HHAT gene
Clone Products
-
GenScript: Next-day shipping cDNA ORF clone for HHAT in any vector
- NM_018194
- NM_001170588
- NM_001170587
- NM_001170580
- NM_001170564
- NM_001122834
- XM_011548834
- XM_011548833
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- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- R&D Systems cDNA Clones for HHAT
Flow Cytometry Products
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||
| SP4: | - | - |
Expression for HHAT Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for HHAT Gene
NURSA nuclear receptor signaling pathways regulating expression of HHAT Gene:
HHATSOURCE GeneReport for Unigene cluster for HHAT Gene:
Hs.58650mRNA Expression by UniProt/SwissProt for HHAT Gene:
Q5VTY9-HHAT_HUMANEvidence on tissue expression from TISSUES for HHAT Gene
- Nervous system(4.4)
- Lung(4.1)
- Skin(2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for HHAT Gene
- ectoderm
- endoderm
- mesoderm
- integumentary
- nervous
- reproductive
- respiratory
- skeletal muscle
- skeleton
- brain
- cerebellum
- cranial nerve
- ear
- eye
- eyelid
- face
- head
- jaw
- mandible
- maxilla
- mouth
- nose
- outer ear
- skull
- chest wall
- clavicle
- lung
- rib
- rib cage
- scapula
- sternum
- ovary
- pelvis
- penis
- testicle
- vagina
- arm
- digit
- femur
- fibula
- finger
- forearm
- hand
- humerus
- lower limb
- radius
- shin
- shoulder
- thigh
- tibia
- ulna
- upper limb
- hair
- peripheral nervous system
- skin
- spinal column
- vertebrae
Primer Products
-
OriGene qPCR primer pairs for HHAT
-
OriGene qPCR primer pairs and template standards for HHAT
No data available for mRNA differential expression in normal tissues for HHAT Gene
Orthologs for HHAT Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HHAT 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | HHAT 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Hhat 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Hhat 34 16 35 |
|
||
| cow (Bos Taurus) |
Mammalia | HHAT 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | HHAT 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | HHAT 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | HHAT 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | hhat 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | hhat 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | rasp 34 35 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP002602 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | hhat-2 34 35 |
|
||
| hhat-1 35 |
|
OneToMany | |||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | GUP1 35 |
|
ManyToMany | |
| GUP2 35 37 |
|
ManyToMany |
- Species where no ortholog for HHAT was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for HHAT Gene
Variants for HHAT Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs147954610 | A lung cancer cell line | 210,623,629(+) | GGGCA(A/G)TGAGG | reference, missense | |
| rs757163023 | A melanoma cell line | 210,623,623(+) | TCTTG(A/G)GGGCA | reference, missense | |
| rs1000005042 | -- | 210,532,532(+) | GCCCT(A/G)AACTT | intron-variant | |
| rs1000005379 | -- | 210,417,756(+) | GCCTC(A/C)GACAT | intron-variant | |
| rs1000005654 | -- | 210,657,077(+) | TGTGC(C/T)CCAGT | intron-variant |
Relevant External Links for HHAT Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HHAT Gene
Disorders for HHAT Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| chondrodysplasia-pseudohermaphroditism syndrome |
|
|
| thoracic outlet syndrome |
|
|
| ancylostomiasis |
|
|
| agnathia-otocephaly complex |
|
|
| opportunistic mycosis |
|
|
Relevant External Links for HHAT
No data available for UniProtKB/Swiss-Prot and Genatlas for HHAT Gene
Publications for HHAT Gene
- Isolation of a new melanoma antigen, MART-2, containing a mutated epitope recognized by autologous tumor-infiltrating T lymphocytes. (PMID: 11160356) Kawakami Y. … Rosenberg S. (J. Immunol. 2001) 2 3 4 64
- Membrane topology of hedgehog acyltransferase. (PMID: 25488661) Matevossian A. … Resh M.D. (J. Biol. Chem. 2015) 3 4 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
Products for HHAT Gene
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- Plasmid Preparation
- GenScript Custom Peptide Services for HHAT
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for HHAT
- Novus Biologicals proteins and lysates for HHAT
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for HHAT
- Abcam proteins for HHAT
- Search for Assays for HHAT at Abcam
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- Invitrogen Antibodies for HHAT
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ApexBio compounds for HHAT
- antibodies-online Antibodies for HHAT: See all 35
- antibodies-online Kits for HHAT: See all 2
- Search antibodies-online for proteins
- Search antibodies-online for peptides
- GeneTex HHAT antibody for HHAT
- Search GeneTex for Proteins for HHAT
- ViGene Biosciences adenoviral particle packaged cDNA for HHAT gene
- ViGene Biosciences lentiviral particle packaged cDNA for HHAT gene
- ViGene Biosciences ready-to-package AAV shRNAs for HHAT gene
- Search ViGene Biosciences for HHAT
- Horizon Cell Lines for HHAT
- Cyagen custom Knockout/knockin (KOKI) mouse models for HHAT
- VectorBuilder custom plasmid, inducible vectors for HHAT
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HHAT
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HHAT Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer




