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Aliases for HGH1 Gene

Aliases for HGH1 Gene

  • HGH1 Homolog 2 3 5
  • Family With Sequence Similarity 203, Member B 2 3
  • Family With Sequence Similarity 203, Member A 2 3
  • Brain Protein 16 2 3
  • C8orf30A 3 4
  • C8orf30B 3 4
  • FAM203A 3 4
  • FAM203B 3 4
  • Chromosome 8 Open Reading Frame 30A 2
  • Chromosome 8 Open Reading Frame 30B 2
  • HGH1 Homolog (S. Cerevisiae) 2
  • Brain Protein 16-Like 3
  • Protein HGH1 Homolog 3
  • Protein FAM203A 3
  • Protein FAM203B 3
  • BRP16L 3
  • BRP16 3

External Ids for HGH1 Gene

Previous HGNC Symbols for HGH1 Gene

  • C8orf30A
  • FAM203B
  • C8orf30B
  • FAM203A

Summaries for HGH1 Gene

GeneCards Summary for HGH1 Gene

HGH1 (HGH1 Homolog) is a Protein Coding gene. GO annotations related to this gene include binding.

Additional gene information for HGH1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HGH1 Gene

Genomics for HGH1 Gene

Regulatory Elements for HGH1 Gene

Enhancers for HGH1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08H144796 1.6 Ensembl ENCODE dbSUPER 10 +661.2 661215 4 ARID4B SIN3A DMAP1 ZBTB7B YY1 ZNF207 ZNF143 SP3 SP5 MXD4 ZNF7 CPSF1 RPL8 VPS28 ZNF250 LRRC14 ZNF34 ZNF517 ZNF16 ZNF251
GH08H143453 1.5 Ensembl ENCODE dbSUPER 10 -683.2 -683246 1 PKNOX1 FOXA2 ATF1 ARNT ARID4B SIN3A DMAP1 GTF3C2 ATF7 FOS ZNF623 JRK TIGD5 CPSF1 VPS28 GPAA1 ENSG00000255050 SLC52A2 ZNF707 ZNF696
GH08H144766 1.3 Ensembl ENCODE 10 +630.1 630126 2 ATF1 FOXA2 ARNT ARID4B SIN3A GLI4 GTF3C2 ZNF121 ATF7 FOS RPL8 ZNF251 ZNF7 ZNF16 SLC52A2 LRRC14 ZNF250 ZNF34 CPSF1 GPAA1
GH08H144101 1.2 ENCODE 10.2 -33.9 -33858 3 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 ZNF766 ZNF623 ZNF7 ZNF16 ZNF251 ZNF250 ZNF517 CPSF1 VPS28 ZNF696 LRRC14
GH08H143980 0.9 ENCODE dbSUPER 8.5 -156.6 -156555 0 HDGF ZNF10 YBX1 GLI4 ZNF658 TARDBP CREB1 ZBTB33 PRDM1 HGH1 PIR31620 PLEC
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around HGH1 on UCSC Golden Path with GeneCards custom track

Promoters for HGH1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000232211 131 1401

Genomic Location for HGH1 Gene

Chromosome:
8
Start:
144,137,769 bp from pter
End:
144,140,843 bp from pter
Size:
3,075 bases
Orientation:
Plus strand

Genomic View for HGH1 Gene

Genes around HGH1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HGH1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HGH1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HGH1 Gene

Proteins for HGH1 Gene

  • Protein details for HGH1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BTY7-HGH1_HUMAN
    Recommended name:
    Protein HGH1 homolog
    Protein Accession:
    Q9BTY7
    Secondary Accessions:
    • P0CB43

    Protein attributes for HGH1 Gene

    Size:
    390 amino acids
    Molecular mass:
    42129 Da
    Quaternary structure:
    No Data Available

neXtProt entry for HGH1 Gene

Post-translational modifications for HGH1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for HGH1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for HGH1 Gene

Domains & Families for HGH1 Gene

Gene Families for HGH1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for HGH1 Gene

Suggested Antigen Peptide Sequences for HGH1 Gene

Graphical View of Domain Structure for InterPro Entry

Q9BTY7

UniProtKB/Swiss-Prot:

HGH1_HUMAN :
  • Belongs to the HGH1 family.
Family:
  • Belongs to the HGH1 family.
genes like me logo Genes that share domains with HGH1: view

Function for HGH1 Gene

Phenotypes From GWAS Catalog for HGH1 Gene

Gene Ontology (GO) - Molecular Function for HGH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with HGH1: view

Phenotypes for HGH1 Gene

genes like me logo Genes that share phenotypes with HGH1: view

Animal Model Products

CRISPR Products

miRNA for HGH1 Gene

miRTarBase miRNAs that target HGH1

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for HGH1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HGH1 Gene

Localization for HGH1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for HGH1 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nuclear bodies (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for HGH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with HGH1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for HGH1 Gene

Pathways & Interactions for HGH1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for HGH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with HGH1: view

No data available for Pathways by source and SIGNOR curated interactions for HGH1 Gene

Drugs & Compounds for HGH1 Gene

No Compound Related Data Available

Transcripts for HGH1 Gene

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for HGH1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for HGH1 Gene

No ASD Table

Relevant External Links for HGH1 Gene

GeneLoc Exon Structure for
HGH1
ECgene alternative splicing isoforms for
HGH1

Expression for HGH1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HGH1 Gene

Protein differential expression in normal tissues from HIPED for HGH1 Gene

This gene is overexpressed in Bone (45.7) and Pancreas (16.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for HGH1 Gene



Protein tissue co-expression partners for HGH1 Gene

NURSA nuclear receptor signaling pathways regulating expression of HGH1 Gene:

HGH1
genes like me logo Genes that share expression patterns with HGH1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HGH1 Gene

Orthologs for HGH1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for HGH1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM203A 33
  • 99.11 (n)
-- 34
  • 98 (a)
OneToMany
dog
(Canis familiaris)
Mammalia LOC609695 33
  • 84.17 (n)
-- 34
  • 80 (a)
OneToMany
cow
(Bos Taurus)
Mammalia FAM203A 33
  • 84.13 (n)
-- 34
  • 82 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Fam203a 34 33
  • 80.83 (n)
OneToMany
Hgh1 16
rat
(Rattus norvegicus)
Mammalia Fam203a 33
  • 79.11 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 61 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 54 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 50 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia fam203a 33
  • 60.79 (n)
Str.15925 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.22740 33
zebrafish
(Danio rerio)
Actinopterygii fam203a 34 33
  • 57.65 (n)
ManyToMany
CABZ01049059.1 34
  • 41 (a)
ManyToMany
Dr.16793 33
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.3530 33
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001442 33
  • 51.04 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG6073 33 34
  • 48.27 (n)
worm
(Caenorhabditis elegans)
Secernentea Y54H5A.2 34
  • 22 (a)
OneToMany
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AAL150W 33
  • 45.79 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F15433g 33
  • 43.59 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes HGH1 33 34
  • 40.71 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G14300 33
  • 45.86 (n)
rice
(Oryza sativa)
Liliopsida Os10g0406800 33
  • 41.89 (n)
bread mold
(Neurospora crassa)
Ascomycetes NCU08324 33
  • 48.78 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC26F1.12c 33
  • 46.38 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 41 (a)
OneToMany
Species where no ortholog for HGH1 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for HGH1 Gene

ENSEMBL:
Gene Tree for HGH1 (if available)
TreeFam:
Gene Tree for HGH1 (if available)

Paralogs for HGH1 Gene

No data available for Paralogs for HGH1 Gene

Variants for HGH1 Gene

Sequence variations from dbSNP and Humsavar for HGH1 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1000132029 -- 144,140,959(+) GGTGC(A/G)CTTCT intron-variant
rs1000484401 -- 144,141,173(+) TTGCT(C/T)ACCCA intron-variant
rs1001083812 -- 144,140,145(+) TAAGT(C/T)TTCCT utr-variant-3-prime
rs1001523380 -- 144,136,612(+) GCTCT(C/G)ACAAA upstream-variant-2KB
rs1001536813 -- 144,139,950(+) CTGGG(C/T)AGAGG utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for HGH1 Gene

Variant ID Type Subtype PubMed ID
dgv12431n54 CNV loss 21841781
dgv906n27 CNV loss 19166990
esv2759651 CNV gain 17122850
esv29971 CNV loss 17803354
nsv1025071 CNV gain 25217958
nsv1030888 CNV gain 25217958
nsv1075598 CNV deletion 25765185
nsv1119194 CNV deletion 24896259
nsv1122205 CNV deletion 24896259
nsv1145205 CNV deletion 24896259
nsv428208 CNV gain 18775914
nsv466014 CNV loss 19166990
nsv470249 CNV loss 18288195
nsv515809 CNV gain+loss 19592680
nsv612915 CNV loss 21841781
nsv824802 CNV gain 20364138
nsv824803 CNV gain 20364138
nsv8395 CNV gain+loss 18304495
nsv950016 CNV deletion 24416366

Variation tolerance for HGH1 Gene

Gene Damage Index Score: 0.13; 2.89% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for HGH1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HGH1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HGH1 Gene

Disorders for HGH1 Gene

Relevant External Links for HGH1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HGH1

No disorders were found for HGH1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HGH1 Gene

Publications for HGH1 Gene

  1. N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. (PMID: 22814378) Van Damme P … Aldabe R (Proceedings of the National Academy of Sciences of the United States of America 2012) 3 4 60
  2. Initial characterization of the human central proteome. (PMID: 21269460) Burkard TR … Colinge J (BMC systems biology 2011) 3 4 60
  3. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PMID: 20068231) Olsen JV … Mann M (Science signaling 2010) 3 4 60
  4. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PMID: 19413330) Gauci S … Mohammed S (Analytical chemistry 2009) 3 4 60
  5. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N … Gygi SP (Proceedings of the National Academy of Sciences of the United States of America 2008) 3 4 60

Products for HGH1 Gene

Sources for HGH1 Gene

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