Aliases for HGH1 Gene
Aliases for HGH1 Gene
External Ids for HGH1 Gene
- HGNC: 24161
- Entrez Gene: 51236
- Ensembl: ENSG00000235173
- UniProtKB: Q9BTY7
Previous HGNC Symbols for HGH1 Gene
- C8orf30A
- FAM203B
- C8orf30B
- FAM203A
Summaries for HGH1 Gene
GeneCards Summary for HGH1 Gene
HGH1 (HGH1 Homolog) is a Protein Coding gene. GO annotations related to this gene include binding.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HGH1 Gene
Genomics for HGH1 Gene
Regulatory Elements for HGH1 Gene
Enhancers for HGH1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HGH1 on UCSC Golden Path with GeneCards custom track
Promoters for HGH1 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|---|---|---|
| ENSR00000232211 | 131 | 1401 |
Regulatory Element Products
Genomic Location for HGH1 Gene
- Chromosome:
- 8
- Start:
- 144,137,769 bp from pter
- End:
- 144,140,843 bp from pter
- Size:
- 3,075 bases
- Orientation:
- Plus strand
Genomic View for HGH1 Gene
Genes around HGH1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8q24.3 by Ensembl
- 8q24.3 by Entrez Gene
- 8q24.3 by HGNC
HGH1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HGH1 Gene
Proteins for HGH1 Gene
-
Protein details for HGH1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BTY7-HGH1_HUMAN
- Recommended name:
- Protein HGH1 homolog
- Protein Accession:
- Q9BTY7
- P0CB43
Protein attributes for HGH1 Gene
- Size:
- 390 amino acids
- Molecular mass:
- 42129 Da
- Quaternary structure:
- No Data Available
Protein Expression for HGH1 Gene
Post-translational modifications for HGH1 Gene
Other Protein References for HGH1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for HGH1
-
Abcam antibodies for HGH1
- Invitrogen Antibodies for HGH1
- Invitrogen Antibodies for HGH1
- GeneTex HGH1 antibody for HGH1
Protein Products
-
OriGene Purified Proteins for HGH1
- Search Origene for MassSpec and Protein Over-expression Lysates for HGH1
- Origene Custom Protein Services for HGH1
- Search GeneTex for Proteins for HGH1
-
Abcam proteins for HGH1
Assay Products
No data available for DME Specific Peptides for HGH1 Gene
Domains & Families for HGH1 Gene
Protein Domains for HGH1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for HGH1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9BTY7- Family:
-
- Belongs to the HGH1 family.
No data available for Gene Families for HGH1 Gene
Function for HGH1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
Phenotypes for HGH1 Gene
- GenomeRNAi human phenotypes for HGH1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for HGH1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HGH1 gene
- Search ViGene Biosciences for HGH1
CRISPR Products
-
OriGene CRISPR knockouts for HGH1
- GenScript: Design CRISPR guide RNA sequences for HGH1
miRNA for HGH1 Gene
- miRTarBase miRNAs that target HGH1
miRNA Products
- Search ViGene Biosciences for HGH1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HGH1
- Browse OriGene Inhibitory RNA Products For HGH1
-
ViGene Biosciences ready-to-package AAV shRNAs for HGH1 gene
Cell Line Products
-
Horizon Cell Lines for HGH1
-
ViGene Biosciences adenoviral particle packaged cDNA for HGH1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HGH1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HGH1 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HGH1 Gene
Localization for HGH1 Gene
| Compartment | Confidence |
|---|---|
| extracellular | 2 |
| nucleus | 2 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005575 | cellular_component | ND | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for HGH1 Gene
Pathways & Interactions for HGH1 Gene
No Data Available
Interacting Proteins for HGH1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008150 | biological_process | ND | -- |
No data available for Pathways by source and SIGNOR curated interactions for HGH1 Gene
Transcripts for HGH1 Gene
mRNA/cDNA for HGH1 Gene
- (1) REFSEQ mRNAs :
- (122) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for HGH1
- GenScript: Design CRISPR guide RNA sequences for HGH1
miRNA Products
- Search ViGene Biosciences for HGH1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HGH1
- Browse OriGene Inhibitory RNA Products For HGH1
-
ViGene Biosciences ready-to-package AAV shRNAs for HGH1 gene
Flow Cytometry Products
Expression for HGH1 Gene
This gene is overexpressed in Bone (45.7) and Pancreas (16.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for HGH1 Gene
NURSA nuclear receptor signaling pathways regulating expression of HGH1 Gene:
HGH1Primer Products
-
OriGene qPCR primer pairs for HGH1
-
OriGene qPCR primer pairs and template standards for HGH1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HGH1 Gene
Orthologs for HGH1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FAM203A 34 |
|
||
| -- 35 |
|
OneToMany | |||
| dog (Canis familiaris) |
Mammalia | LOC609695 34 |
|
||
| -- 35 |
|
OneToMany | |||
| cow (Bos Taurus) |
Mammalia | FAM203A 34 |
|
||
| -- 35 |
|
OneToMany | |||
| mouse (Mus musculus) |
Mammalia | Fam203a 35 34 |
|
OneToMany | |
| Hgh1 16 |
|
||||
| rat (Rattus norvegicus) |
Mammalia | Fam203a 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
OneToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fam203a 34 |
|
||
| Str.15925 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.22740 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | fam203a 34 35 |
|
||
| CABZ01049059.1 35 |
|
ManyToMany | |||
| Dr.16793 34 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.3530 34 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP001442 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG6073 34 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | Y54H5A.2 35 |
|
OneToMany | |
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AAL150W 34 |
|
||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0F15433g 34 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | HGH1 34 35 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT1G14300 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os10g0406800 34 |
|
||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU08324 34 |
|
||
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | SPAC26F1.12c 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for HGH1 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for HGH1 Gene
No data available for Paralogs for HGH1 Gene
Variants for HGH1 Gene
| SNP ID | Clin | Chr 08 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000132029 | -- | 144,140,959(+) | GGTGC(A/G)CTTCT | intron-variant | |
| rs1000484401 | -- | 144,141,173(+) | TTGCT(C/T)ACCCA | intron-variant | |
| rs1001083812 | -- | 144,140,145(+) | TAAGT(C/T)TTCCT | utr-variant-3-prime | |
| rs1001523380 | -- | 144,136,612(+) | GCTCT(C/G)ACAAA | upstream-variant-2KB | |
| rs1001536813 | -- | 144,139,950(+) | CTGGG(C/T)AGAGG | utr-variant-3-prime |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv12431n54 | CNV | loss | 21841781 |
| dgv906n27 | CNV | loss | 19166990 |
| esv2759651 | CNV | gain | 17122850 |
| esv29971 | CNV | loss | 17803354 |
| nsv1025071 | CNV | gain | 25217958 |
| nsv1030888 | CNV | gain | 25217958 |
| nsv1075598 | CNV | deletion | 25765185 |
| nsv1119194 | CNV | deletion | 24896259 |
| nsv1122205 | CNV | deletion | 24896259 |
| nsv1145205 | CNV | deletion | 24896259 |
| nsv428208 | CNV | gain | 18775914 |
| nsv466014 | CNV | loss | 19166990 |
| nsv470249 | CNV | loss | 18288195 |
| nsv515809 | CNV | gain+loss | 19592680 |
| nsv612915 | CNV | loss | 21841781 |
| nsv824802 | CNV | gain | 20364138 |
| nsv824803 | CNV | gain | 20364138 |
| nsv8395 | CNV | gain+loss | 18304495 |
| nsv950016 | CNV | deletion | 24416366 |
Gene Damage Index Score:
0.13;
2.89% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HGH1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HGH1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HGH1 Gene
Disorders for HGH1 Gene
Relevant External Links for HGH1
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- HGH1
No disorders were found for HGH1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HGH1 Gene
Publications for HGH1 Gene
- N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PMID: 22814378) Van Damme P. … Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012) 3 4 64
- Initial characterization of the human central proteome. (PMID: 21269460) Burkard T.R. … Colinge J. (BMC Syst. Biol. 2011) 3 4 64
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PMID: 20068231) Olsen J.V. … Mann M. (Sci. Signal. 2010) 3 4 64
- Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PMID: 19413330) Gauci S. … Mohammed S. (Anal. Chem. 2009) 3 4 64
- A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008) 3 4 64
Products for HGH1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for HGH1
- Search Origene for MassSpec and Protein Over-expression Lysates for HGH1
- Origene Custom Protein Services for HGH1
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HGH1
- Browse OriGene Inhibitory RNA Products For HGH1
- OriGene qPCR primer pairs and template standards for HGH1
- OriGene qPCR primer pairs for HGH1
- OriGene CRISPR knockouts for HGH1
- OriGene ORF clones in human for HGH1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HGH1
- GenScript: Next-day shipping cDNA ORF clone for HGH1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for HGH1
- GenScript Custom Assay Services for HGH1
- GenScript Custom overexpressing Cell Line Services for HGH1
- GenScript: Design CRISPR guide RNA sequences for HGH1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for HGH1
- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
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- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for HGH1
- Novus Biologicals proteins and lysates for HGH1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for HGH1
- Abcam proteins for HGH1
- Search for Assays for HGH1 at Abcam
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- Invitrogen Antibodies for HGH1
- Invitrogen Antibodies for HGH1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ViGene Biosciences adenoviral particle packaged cDNA for HGH1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for HGH1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for HGH1 gene
- Search ViGene Biosciences for HGH1
- Horizon Cell Lines for HGH1
- Cyagen custom Knockout/knockin (KOKI) mouse models for HGH1
- VectorBuilder custom plasmid, inducible vectors for HGH1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HGH1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HGH1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer