Aliases for HEYL Gene
Aliases for HEYL Gene
External Ids for HEYL Gene
- HGNC: 4882
- Entrez Gene: 26508
- Ensembl: ENSG00000163909
- OMIM: 609034
- UniProtKB: Q9NQ87
Previous GeneCards Identifiers for HEYL Gene
- GC01M040119
- GC01M039093
- GC01M039553
- GC01M039503
- GC01M039492
- GC01M039741
- GC01M039862
- GC01M038207
Summaries for HEYL Gene
-
This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for HEYL Gene
HEYL (Hes Related Family BHLH Transcription Factor With YRPW Motif-Like) is a Protein Coding gene. Diseases associated with HEYL include Glaucoma 1, Open Angle, E. Among its related pathways are Signaling by NOTCH1 and HIV Life Cycle. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and sequence-specific DNA binding. An important paralog of this gene is HEY1.
UniProtKB/Swiss-Prot for HEYL Gene
-
Downstream effector of Notch signaling which may be required for cardiovascular development (By similarity). Transcriptional repressor which binds preferentially to the canonical E box sequence 5-CACGTG-3 (By similarity). Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HEYL Gene
Genomics for HEYL Gene
Regulatory Elements for HEYL Gene
Enhancers for HEYL Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HEYL on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the HEYL gene promoter:
Regulatory Element Products
Genomic Location for HEYL Gene
- Chromosome:
- 1
- Start:
- 39,623,431 bp from pter
- End:
- 39,639,945 bp from pter
- Size:
- 16,515 bases
- Orientation:
- Minus strand
Genomic View for HEYL Gene
Genes around HEYL on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p34.2 by Ensembl
- 1p34.2 by Entrez Gene
- 1p34.2 by HGNC
HEYL Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HEYL Gene
Proteins for HEYL Gene
-
Protein details for HEYL Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NQ87-HEYL_HUMAN
- Recommended name:
- Hairy/enhancer-of-split related with YRPW motif-like protein
- Protein Accession:
- Q9NQ87
- Q5TG99
Protein attributes for HEYL Gene
- Size:
- 328 amino acids
- Molecular mass:
- 35087 Da
- Quaternary structure:
-
- Self-associates. Interacts with GATA4, GATA6, HES1, HEY1 and HEY2. Interacts with HDAC1, NCOR1 and SIN3A.
Protein Expression for HEYL Gene
Post-translational modifications for HEYL Gene
Other Protein References for HEYL Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for HEYL
- Novus Biologicals Antibodies for HEYL
- Invitrogen Antibodies for HEYL
- antibodies-online Antibodies for HEYL: See all 54
- GeneTex HEYL antibody for HEYL
-
Santa Cruz Biotechnology (SCBT) Antibodies for HEYL
Protein Products
-
OriGene Purified Proteins for HEYL
- Search Origene for MassSpec and Protein Over-expression Lysates for HEYL
- Origene Custom Protein Services for HEYL
- antibodies-online Proteins for HEYL: See all 7
- Search antibodies-online for peptides
- Search GeneTex for Proteins for HEYL
Assay Products
- antibodies-online Kits for HEYL: See all 1
No data available for DME Specific Peptides for HEYL Gene
Domains & Families for HEYL Gene
Gene Families for HEYL Gene
Protein Domains for HEYL Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for HEYL Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9NQ87- Family:
-
- Belongs to the HEY family.
Function for HEYL Gene
Molecular function for HEYL Gene
- UniProtKB/Swiss-Prot Function:
- Downstream effector of Notch signaling which may be required for cardiovascular development (By similarity). Transcriptional repressor which binds preferentially to the canonical E box sequence 5-CACGTG-3 (By similarity). Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
- UniProtKB/Swiss-Prot Induction:
- By activation of the Notch signaling pathway.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | IEA | -- |
| GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific | IEA,ISS | -- |
| GO:0000988 | transcription factor activity, protein binding | IDA | 21290414 |
| GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | IEA | -- |
| GO:0001106 | RNA polymerase II transcription corepressor activity | IEA | -- |
Phenotypes for HEYL Gene
- MGI mutant phenotypes for HEYL:
- inferred from 5 alleles
- GenomeRNAi human phenotypes for HEYL:
Animal Models for HEYL Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for HEYL gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HEYL gene
- Search ViGene Biosciences for HEYL
CRISPR Products
-
OriGene CRISPR knockouts for HEYL
-
Santa Cruz Biotechnology (SCBT) CRISPR for HEYL
- GenScript: Design CRISPR guide RNA sequences for HEYL
miRNA for HEYL Gene
- miRTarBase miRNAs that target HEYL
-
- hsa-mir-93-3p (MIRT038777)
- hsa-mir-765 (MIRT475701)
- hsa-mir-6081 (MIRT475702)
- hsa-mir-4722-5p (MIRT475703)
- hsa-mir-4726-3p (MIRT475704)
- hsa-mir-6764-5p (MIRT475705)
- hsa-mir-1915-3p (MIRT475706)
- hsa-mir-6840-3p (MIRT475707)
- hsa-mir-4768-3p (MIRT475708)
- hsa-mir-761 (MIRT475709)
- hsa-mir-3619-5p (MIRT475710)
- hsa-mir-214-3p (MIRT475711)
- hsa-mir-4733-5p (MIRT475712)
- hsa-mir-6838-5p (MIRT475713)
- hsa-mir-6165 (MIRT475714)
- hsa-mir-497-5p (MIRT475715)
- hsa-mir-424-5p (MIRT475716)
- hsa-mir-195-5p (MIRT475717)
- hsa-mir-16-5p (MIRT475718)
- hsa-mir-15b-5p (MIRT475719)
- hsa-mir-15a-5p (MIRT475720)
- hsa-mir-4291 (MIRT495074)
- hsa-mir-668-5p (MIRT495075)
- hsa-mir-6787-3p (MIRT495076)
- hsa-mir-339-3p (MIRT495077)
- hsa-mir-5685 (MIRT495078)
- hsa-mir-4690-3p (MIRT495079)
- hsa-mir-922 (MIRT495080)
- hsa-mir-665 (MIRT544152)
- hsa-mir-1273e (MIRT544153)
- hsa-mir-6716-5p (MIRT544154)
- hsa-mir-4763-3p (MIRT544155)
- hsa-mir-1207-5p (MIRT544156)
- hsa-mir-7160-5p (MIRT544157)
- hsa-mir-6722-3p (MIRT544158)
- hsa-mir-1909-3p (MIRT544159)
- hsa-mir-6884-5p (MIRT544160)
- hsa-mir-485-5p (MIRT544161)
- hsa-mir-1827 (MIRT544162)
- hsa-mir-4649-3p (MIRT544163)
- hsa-mir-135b-5p (MIRT544164)
- hsa-mir-135a-5p (MIRT544165)
- hsa-mir-6783-5p (MIRT544166)
- hsa-mir-4478 (MIRT544167)
- hsa-mir-4419b (MIRT544168)
- hsa-mir-3929 (MIRT544169)
- hsa-mir-940 (MIRT544170)
- hsa-mir-6808-5p (MIRT544171)
- hsa-mir-6893-5p (MIRT544172)
- hsa-mir-2276-3p (MIRT623708)
- hsa-mir-7641 (MIRT640793)
- hsa-mir-4279 (MIRT640794)
- hsa-mir-642a-5p (MIRT640795)
- hsa-mir-4436b-5p (MIRT640796)
- hsa-mir-4695-3p (MIRT640797)
- hsa-mir-4469 (MIRT640798)
- hsa-mir-2276-5p (MIRT640799)
- hsa-mir-5092 (MIRT640800)
- hsa-mir-4638-5p (MIRT657446)
- hsa-mir-1307-3p (MIRT657447)
- hsa-mir-6741-3p (MIRT657448)
- hsa-mir-4693-5p (MIRT657449)
- hsa-mir-4699-3p (MIRT657450)
- hsa-mir-892c-3p (MIRT657451)
- hsa-mir-4676-3p (MIRT657452)
- hsa-mir-452-5p (MIRT657453)
- hsa-mir-6892-3p (MIRT657454)
- hsa-mir-24-3p (MIRT667960)
- hsa-mir-4284 (MIRT667961)
- hsa-mir-4772-3p (MIRT667962)
- hsa-mir-6880-3p (MIRT667963)
- hsa-mir-4485-5p (MIRT667964)
- hsa-mir-335-5p (MIRT667965)
- hsa-mir-5698 (MIRT671664)
- hsa-mir-6818-3p (MIRT671665)
- hsa-mir-143-5p (MIRT671666)
- hsa-mir-4430 (MIRT671667)
- hsa-mir-3652 (MIRT671668)
- hsa-mir-504-3p (MIRT671669)
- hsa-mir-3135b (MIRT671670)
- hsa-mir-6499-3p (MIRT671671)
- hsa-mir-3655 (MIRT671672)
- hsa-mir-1304-3p (MIRT671673)
miRNA Products
- Search ViGene Biosciences for HEYL
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for HEYL
- Browse OriGene Inhibitory RNA Products For HEYL
-
ViGene Biosciences ready-to-package AAV shRNAs for HEYL gene
Clone Products
- Sino Biological Human cDNA Clone for HEYL
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
- ESI BIO PureStem ES-210, Ecto-ntu Progenitor for HEYL
-
Horizon Cell Lines for HEYL
-
ViGene Biosciences adenoviral particle packaged cDNA for HEYL gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HEYL gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HEYL gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HEYL Gene
Localization for HEYL Gene
Subcellular locations from UniProtKB/Swiss-Prot for HEYL Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| mitochondrion | 2 |
| cytosol | 2 |
| plasma membrane | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA,IEA | 21454491 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005737 | cytoplasm | IEA,ISS | -- |
Pathways & Interactions for HEYL Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Signaling by NOTCH1 | ||
| 2 | HIV Life Cycle |
.45
|
|
| 3 | Glioma |
.36
|
|
| 4 | Signaling by GPCR | ||
Pathways by source for HEYL Gene
1 KEGG pathway for HEYL Gene
Interacting Proteins for HEYL Gene
Selected Interacting proteins:
Q9NQ87-HEYL_HUMAN
ENSP00000361943
for HEYL Gene via
MINT
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | IEA | -- |
| GO:0003151 | outflow tract morphogenesis | IEA,ISS | -- |
| GO:0003181 | atrioventricular valve morphogenesis | IEA,ISS | -- |
| GO:0003184 | pulmonary valve morphogenesis | ISS,IEA | -- |
| GO:0003198 | epithelial to mesenchymal transition involved in endocardial cushion formation | IEA,ISS | -- |
Transcripts for HEYL Gene
mRNA/cDNA for HEYL Gene
- (2) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (139) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HEYL Gene
CRISPR Products
-
OriGene CRISPR knockouts for HEYL
-
Santa Cruz Biotechnology (SCBT) CRISPR for HEYL
- GenScript: Design CRISPR guide RNA sequences for HEYL
miRNA Products
- Search ViGene Biosciences for HEYL
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for HEYL
- Browse OriGene Inhibitory RNA Products For HEYL
-
ViGene Biosciences ready-to-package AAV shRNAs for HEYL gene
Clone Products
- Sino Biological Human cDNA Clone for HEYL
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for HEYL Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Hair (Integumentary System)
- Fetal Matrix Cells Hair Follicle
- Fetal Inner Root Sheath Cells Inner Root Sheath
- Fetal Hair Shaft Cuticle Cells Hair Shaft
- Fetal Medulla Cells Hair Shaft
- Fetal Cortex Cells Hair Shaft
-
Epithelial Cells
- Fetal Matrix Cells Hair Follicle
- Fetal Inner Root Sheath Cells Inner Root Sheath
- Fetal Hair Shaft Cuticle Cells Hair Shaft
- Fetal Medulla Cells Hair Shaft
- Fetal Cortex Cells Hair Shaft
- Bone (Muscoskeletal System)
-
Kidney (Urinary System)
- Cortical Stroma Cells Interstitial Stroma
- Renal Vesicle
- Interstitial Stroma
- Metanephros
- Cartilage (Muscoskeletal System)
-
Heart (Cardiovascular System)
- Atrioventricular Node Cells Atrioventricular Node
- Blood (Hematopoietic System)
- Neural Ectoderm (Nervous System)
mRNA differential expression in normal tissues according to GTEx for HEYL Gene
This gene is overexpressed in Artery - Coronary (x6.7), Artery - Tibial (x4.2), and Pancreas (x4.0).
This gene is overexpressed in Islet of Langerhans (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for HEYL Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of HEYL Gene:
HEYLSOURCE GeneReport for Unigene cluster for HEYL Gene:
Hs.472566Evidence on tissue expression from TISSUES for HEYL Gene
- Muscle(4.4)
- Eye(2.6)
Primer Products
-
OriGene qPCR primer pairs and template standards for HEYL
-
OriGene qPCR primer pairs for HEYL
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HEYL Gene
Orthologs for HEYL Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HEYL 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | HEYL 34 |
|
||
| cow (Bos Taurus) |
Mammalia | HEYL 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Heyl 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Heyl 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | HEYL 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | HEYL 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | HEYL 34 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | heyl 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | Hey 36 35 |
|
- Species where no ortholog for HEYL was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for HEYL Gene
Variants for HEYL Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000031229 | -- | 39,634,341(+) | CTGCC(C/T)GCCTT | intron-variant, upstream-variant-2KB | |
| rs1000139009 | -- | 39,641,668(+) | AGGCT(G/T)TATTA | upstream-variant-2KB | |
| rs1000142660 | -- | 39,631,787(+) | AGTAC(A/T)ACTCA | intron-variant | |
| rs1000416735 | -- | 39,638,535(+) | AGAGA(C/T)GAAGT | intron-variant | |
| rs1000425551 | -- | 39,631,950(+) | AGGTC(A/G)TGAGA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3367103 | CNV | duplication | 20981092 |
| nsv1116447 | OTHER | inversion | 24896259 |
| nsv566 | CNV | insertion | 18451855 |
| nsv7177 | OTHER | inversion | 18451855 |
| nsv829649 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
78.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.64;
31.50% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HEYL Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HEYL Gene
Disorders for HEYL Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| glaucoma 1, open angle, e |
|
|
Search HEYL in MalaCards
View complete list of genes associated with diseases
Relevant External Links for HEYL
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- HEYL
No data available for UniProtKB/Swiss-Prot and Genatlas for HEYL Gene
Publications for HEYL Gene
- Characterization of the human and mouse HEY1, HEY2, and HEYL genes: cloning, mapping, and mutation screening of a new bHLH gene family. (PMID: 10860664) Steidl C. … Gessler M. (Genomics 2000) 2 3 4 22 64
- Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanism. (PMID: 15485867) Kathiriya I.S. … Nakagawa O. (J. Biol. Chem. 2004) 3 4 64
- Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes. (PMID: 10964718) Maier M.M. … Gessler M. (Biochem. Biophys. Res. Commun. 2000) 3 4 64
- Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling. (PMID: 11095750) Nakagawa O. … Olson E.N. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 4 64
- Hey genes: a novel subfamily of hairy- and enhancer of split related genes specifically expressed during mouse embryogenesis. (PMID: 10415358) Leimeister C. … Gessler M. (Mech. Dev. 1999) 2 3 64
Products for HEYL Gene
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- OriGene Purified Proteins for HEYL
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- GenScript: Design CRISPR guide RNA sequences for HEYL
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- CloneReady with Over 120,000 Genes
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- Novus Biologicals Antibodies for HEYL
- Novus Biologicals proteins and lysates for HEYL
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ESI BIO PureStem ES-210, Ecto-ntu Progenitor for HEYL
- antibodies-online Antibodies for HEYL: See all 54
- antibodies-online Kits for HEYL: See all 1
- antibodies-online Proteins for HEYL: See all 7
- Search antibodies-online for peptides
- GeneTex HEYL antibody for HEYL
- Search GeneTex for Proteins for HEYL
- ViGene Biosciences adenoviral particle packaged cDNA for HEYL gene
- ViGene Biosciences lentiviral particle packaged cDNA for HEYL gene
- ViGene Biosciences ready-to-package AAV shRNAs for HEYL gene
- Search ViGene Biosciences for HEYL
- Santa Cruz Biotechnology (SCBT) Antibodies for HEYL
- Search Santa Cruz Biotechnology (SCBT) for HEYL siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HEYL
- Horizon Cell Lines for HEYL
- Cyagen custom Knockout/knockin (KOKI) mouse models for HEYL
- VectorBuilder custom plasmid, inducible vectors for HEYL
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HEYL
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HEYL Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
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