HEXIM1 Gene
protein-coding GIFtS: 52
GCID: GC17P043224
|
|
hexamethylene bis-acetamide inducible 1
| |
Aliases
for HEXIM1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Hexamethylene Bis-Acetamide Inducible 11 2 | | Menage A Quatre Protein 12 3 | | HIS11 2 3 5 | | CLP-11 | | EDG11 2 3 | | HMBA-Inducible1 | | MAQ11 2 3 | | Hexamethylene Bisacetamide-Inducible Protein2 | | CLP12 3 5 | | Hexamethylene-Bis-Acetamide-Inducible Transcript 12 | | Cardiac Lineage Protein 12 3 | | Hexamthylene Bis-Acetamide Inducible 12 | | Estrogen Down-Regulated Gene 1 Protein2 3 | | Menage A Quatre 12 | | Hexamethylene Bis-Acetamide-Inducible Protein 12 3 | | Protein HEXIM12 |
Export aliases for HEXIM1 gene to outside databasesPrevious GC identifers: GC17P040583 GC17P038987 |
Summaries
for HEXIM1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for HEXIM1:
Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has nointrons. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: HEXI1_HUMAN, O94992Function: Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Incooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase IIphosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 andCIITA-dependent transcriptional activity
Gene Wiki entry for HEXIM1
|
Genomic Views
for HEXIM1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HEXIM1 gene promoter:
E2F-4 E2F-3a E2F-5 E2F-1 E2F E2F-2 Nkx2-5 C/EBPalpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for HEXIM1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HEXIM1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q21.31 Ensembl cytogenetic band: 17q21.31 HGNC cytogenetic band: 17q21.31HEXIM1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P043224: view genomic region
(about GC identifiers)
Start:
|
43,224,684 bp from pter |
End:
|
43,229,468 bp from pter |
Size:
|
4,785 bases |
Orientation:
|
plus strand |
|
Proteins
for HEXIM1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: HEXI1_HUMAN, O94992 (See
protein sequence)Recommended Name: Protein HEXIM1 Size: 359 amino acids; 40623 Da
Subunit: Homooligomer and heterooligomer with HEXIM2; probably dimeric. Component of the 7SK snRNP complex at leastcomposed of P-TEFb (composed of CDK9 and CCNT1/cyclin-T1), HEXIM1, HEXIM2, BCDIN3, SART3 proteins and 7SK and U6snRNAs. Interacts with the N-CoR complex through NCOR1. Interacts with ESR1 and NR3C1. May interact with NF-kappa-Bthrough RELA
Subcellular location: Nucleus. Cytoplasm. Note=Binds alpha-importin and is mostly nuclear
Miscellaneous: Inhibits Tat activity which is required for HIV-1 transcription
2 PDB 3D structures from  and Proteopedia  for HEXIM1:2GD7 (3D)
3S9G (3D)
Secondary accessions: B2R8Y5Explore the universe of human proteins at neXtProt for HEXIM1: NX_O94992
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O94992
HEXIM1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_006451.1
ENSEMBL proteins: ENSP00000328773
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
HEXIM1 for ontologies About GeneDecksing
HEXIM1 Antibody Products:
Assay Products for HEXIM1: |
Protein
Domains /
Families
for HEXIM1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HEXIM1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O94992ProtoNet protein and cluster: O94992 UniProtKB/Swiss-Prot: HEXI1_HUMAN, O94992Domain: The coiled-coil domain mediates oligomerizationSimilarity: Belongs to the HEXIM family |
Function
for HEXIM1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: HEXI1_HUMAN, O94992Function: Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Incooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase IIphosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 andCIITA-dependent transcriptional activityInduction: Up-regulated by HMBA (hexamethylene bisacetamide) (at protein level). Down-regulated by estrogen
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HEXIM1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HEXIM1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HEXIM1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
HEXIM1 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Hexim1tm1Maqs for HEXIM1
3 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Hexim1):
HEXIM1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for HEXIM1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Chromatin Regulation / Acetylation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for HEXIM1
HEXIM1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HEXIM1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 16)
5/16 Interacting proteins for HEXIM1 (O949922, 3 ENSP000003287734) via UniProtKB, MINT, STRING, and/or I2D (see all 16)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
HEXIM1 for ontologies About GeneDecksing
|
Drugs & Compounds
for HEXIM1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
HEXIM1 for compounds About GeneDecksing
 Browse Tocris compounds for HEXIM1
2 Novoseek chemical compound relationships for HEXIM1 gene About this table
Search CenterWatch for drugs/clinical trials and news about HEXIM1 / HEXI1
|
Transcripts
for HEXIM1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HEXIM1 gene: NM_006460.2 Unigene Cluster for HEXIM1: Hexamethylene bis-acetamide inducible 1 Hs.15299 [show with all ESTs]Unigene Representative Sequence: NM_0064601 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000332499(uc002iig.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HEXIM1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HEXIM1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: HEXIM1 (NM_006460) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HEXIM1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HEXIM1 |
Additional cDNA sequence: AB021179.1 AK023624.1 AK313557.1 BC006460.1 6 DOTS entries: DT.452673 DT.100784252 DT.80100469 DT.120957342 DT.95169476 DT.95169482 24/165 AceView cDNA sequences (see all 165): BU073220 CA865829 CB853296 AW471147 CR617663 BQ221641 AI095721 AA902436 AI160507 W68584 BM719071 AI364065 BM915356 N40566 CK000745 AI572240 CD671077 N57225 Z40405 AA630587 CD518239 AI061204 AI685477 AI590074
GeneLoc Exon Structure
|
Expression
for HEXIM1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HEXIM1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTTTGCAGT
About this image
See HEXIM1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HEXIM1
SOURCE GeneReport for Unigene cluster: Hs.15299
UniProtKB/Swiss-Prot: HEXI1_HUMAN, O94992Tissue specificity: Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentiallyexpressed. Expressed in endocrine tissues
SABiosciences Custom PCR Arrays for HEXIM1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HEXIM1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HEXIM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HEXIM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HEXIM1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HEXIM1 |
Orthologs
for HEXIM1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for HEXIM1 gene from 5/16 species (see all 16) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
LOC1008577961 |
protein HEXIM1-like |
81.36(n)
80.65(a) |
|
100857796 XM_003642783.1 XP_003642831.1 |
lizard
(Anolis carolinensis) |
Reptilia |
HEXIM16 |
-- |
81(a) |
1 ↔ 1 |
6(64979308-64979961) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.25892 |
Xenopus laevis transcribed sequence with weak similarity more |
76.53(n) |
|
CA789057.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufd44h022 |
Transcribed sequence with weak similarity to protein more |
78.41(n) |
|
CD752877.1 |
honey bee
(Apis mellifera) |
Insecta |
-- |
-- |
16(a) |
1 → many |
Group5.20(2349-3862) |
ENSEMBL Gene Tree for HEXIM1 (if available)
TreeFam Gene Tree for HEXIM1 (if available) |
Paralogs
for HEXIM1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for HEXIM1 gene
- HEXIM22
1 SIMAP similar gene for HEXIM1 using alignment to 1 protein entry: HEXI1_HUMAN:HEXIM2
HEXIM1 for paralogs About GeneDecksing
|
Genomic Variants
for HEXIM1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HEXIM1 (43224684 - 43229468 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for HEXIM1
2 CNVs: 34646 35464 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HEXIM1 |
|
Disorders
/ Diseases
for HEXIM1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HEXIM1 for disorders About GeneDecksing
OMIM gene information: 607328
OMIM disorders: --
2  diseases for HEXIM1: About MalaCardsimmunodeficiency neuroblastoma
2 Novoseek disease relationships for HEXIM1 gene About this table
Export disorders for HEXIM1 gene to outside databases
|
Publications
for HEXIM1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HEXIM1 gene, integrated from 9 sources (see all 92):
(articles sorted by number of sources associating them with HEXIM1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner. (PubMed id 12832472)1, 2, 3 Michels A.A....Bensaude O. (2003)
- HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b. (PubMed id 15941832)1, 2, 9 Shimizu N.... Tanaka H. (2005)
- A human immunodeficiency virus type 1 Tat-like arginine-rich RNA- binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb. (PubMed id 15169877)1, 2, 9 Yik J.H.N.... Zhou Q. (2004)
- Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186. (PubMed id 15965233)1, 2, 9 Li Q.... Price D.H. (2005)
- Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA. (PubMed id 14580347)1, 2, 9 Yik J.H.N.... Zhou Q. (2003)
- Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription. (PubMed id 15713661)1, 2, 9 Yik J.H.N.... Zhou Q. (2005)
- Interplay between 7SK snRNA and oppositely charged regions in HEXIM1 direct the inhibition of P-TEFb. (PubMed id 16362050)1, 2, 9 Barboric M....Peterlin B.M. (2005)
- Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells. (PubMed id 12581153)1, 2, 9 Ouchida R.... Tanaka H. (2003)
- Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. (PubMed id 17643375)1, 2 Jeronimo C.... Coulombe B. (2007)
- Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb. (PubMed id 17724342)1, 2 Dames S.A.... Geyer M. (2007)
|
External Searches for HEXIM1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HEXIM1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HEXIM1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HEXIM1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for HEXIM1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for HEXIM1 gene:
Search GeneIP for patents involving HEXIM1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HEXIM1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for HEXIM1 | | OriGene shRNA RFP for HEXIM1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HEXIM1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HEXIM1 | | | OriGene Protein Over-expression Lysate for HEXIM1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HEXIM1 | | OriGene 3'-UTR Clone for HEXIM1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HEXIM1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HEXIM1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HEXIM1 | | OriGene Custom Protein Services for HEXIM1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HEXIM1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HEXIM1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HEXIM1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HEXIM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HEXIM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HEXIM1 |
| |
 |  |  |  | |
| | Antibodies & Assays for HEXIM1 |
| | | | Search Tocris compounds for HEXIM1 |
| |  |  |  |  | | | | | | Recombinant Protein for HEXIM1 |
|
 |
 |
 |
 | | | HEXIM1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HEXIM1 |
|  |  |  | | | | ThermoFisher Antibodies for HEXIM1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HEXIM1 |
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