Aliases for HES4 Gene
Aliases for HES4 Gene
External Ids for HES4 Gene
- HGNC: 24149
- Entrez Gene: 57801
- Ensembl: ENSG00000188290
- OMIM: 608060
- UniProtKB: Q9HCC6
Previous GeneCards Identifiers for HES4 Gene
- GC01M000974
- GC01M000924
- GC01M000206
Summaries for HES4 Gene
GeneCards Summary for HES4 Gene
HES4 (Hes Family BHLH Transcription Factor 4) is a Protein Coding gene. GO annotations related to this gene include transcription factor binding and protein dimerization activity. An important paralog of this gene is HES1.
UniProtKB/Swiss-Prot for HES4 Gene
-
Transcriptional repressor. Binds DNA on N-box motifs: 5-CACNAG-3 (By similarity).
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HES4 Gene
Genomics for HES4 Gene
Regulatory Elements for HES4 Gene
Enhancers for HES4 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HES4 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the HES4 gene promoter:
Regulatory Element Products
Genomic Location for HES4 Gene
- Chromosome:
- 1
- Start:
- 998,962 bp from pter
- End:
- 1,001,285 bp from pter
- Size:
- 2,324 bases
- Orientation:
- Minus strand
Genomic View for HES4 Gene
Genes around HES4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p36.33 by Ensembl
- 1p36.33 by Entrez Gene
- 1p36.33 by HGNC
HES4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HES4 Gene
Proteins for HES4 Gene
-
Protein details for HES4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9HCC6-HES4_HUMAN
- Recommended name:
- Transcription factor HES-4
- Protein Accession:
- Q9HCC6
- Q5SVA5
Protein attributes for HES4 Gene
- Size:
- 221 amino acids
- Molecular mass:
- 23523 Da
- Quaternary structure:
-
- Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family.
Post-translational modifications for HES4 Gene
Other Protein References for HES4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for HES4 (HES-4)
- Novus Biologicals Antibodies for HES4
-
Abcam antibodies for HES4
- Invitrogen Antibodies for HES4
- antibodies-online Antibodies for HES4: See all 36
- GeneTex HES4 antibody for HES4
-
Santa Cruz Biotechnology (SCBT) Antibodies for HES4
Protein Products
-
OriGene Purified Proteins for HES4
- Search Origene for MassSpec and Protein Over-expression Lysates for HES4
- Origene Custom Protein Services for HES4
- antibodies-online Proteins for HES4: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Proteins for HES4
-
Abcam proteins for HES4
No data available for DME Specific Peptides for HES4 Gene
Domains & Families for HES4 Gene
Gene Families for HES4 Gene
Protein Domains for HES4 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for HES4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9HCC6UniProtKB/Swiss-Prot:
HES4_HUMAN :- Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).
- Domain:
-
- Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).
- The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins.
Function for HES4 Gene
Molecular function for HES4 Gene
- UniProtKB/Swiss-Prot Function:
- Transcriptional repressor. Binds DNA on N-box motifs: 5-CACNAG-3 (By similarity).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0008134 | transcription factor binding | NAS | 17611704 |
| GO:0046983 | protein dimerization activity | IEA | -- |
Phenotypes for HES4 Gene
- GenomeRNAi human phenotypes for HES4:
-
- Increased vaccinia virus (VACV) infection
- Decreased viability
- shRNA abundance <= 50%
- Increased transferrin (TF) endocytosis
- Decreased shRNA abundance (Z-score < -2)
- Decreased IL-8 secretion
- Increased shRNA abundance (Z-score > 2)
- Synthetic lethal with vaccinia virus (VACV) infection
- Decreased Hepatitis C virus replication
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for HES4
-
-
ViGene Biosciences lentiviral particle packaged cDNA for HES4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HES4 gene
- Search ViGene Biosciences for HES4
CRISPR Products
-
OriGene CRISPR knockouts for HES4
-
Applied Biological Materials CRISPR for HES4
-
Santa Cruz Biotechnology (SCBT) CRISPR for HES4
- GenScript: Design CRISPR guide RNA sequences for HES4
miRNA for HES4 Gene
- miRTarBase miRNAs that target HES4
-
- hsa-mir-423-5p (MIRT038130)
- hsa-mir-149-5p (MIRT045541)
- hsa-mir-6720-5p (MIRT453146)
- hsa-mir-6512-3p (MIRT453147)
- hsa-mir-5581-5p (MIRT453148)
- hsa-mir-4297 (MIRT453149)
- hsa-mir-6880-3p (MIRT453150)
- hsa-mir-4699-5p (MIRT453151)
- hsa-mir-4530 (MIRT453152)
- hsa-mir-338-3p (MIRT453153)
- hsa-mir-3065-3p (MIRT453154)
- hsa-mir-181d-3p (MIRT453155)
- hsa-mir-4314 (MIRT486735)
miRNA Products
- Search ViGene Biosciences for HES4
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HES4
- Browse OriGene Inhibitory RNA Products For HES4
-
ViGene Biosciences ready-to-package AAV shRNAs for HES4 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for HES4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HES4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for HES4
-
ViGene Biosciences adenoviral particle packaged cDNA for HES4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HES4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HES4 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HES4 Gene
Localization for HES4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HES4 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
Pathways & Interactions for HES4 Gene
No Data Available
Interacting Proteins for HES4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0007399 | nervous system development | IEA | -- |
| GO:0030154 | cell differentiation | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for HES4 Gene
Transcripts for HES4 Gene
mRNA/cDNA for HES4 Gene
- (3) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (65) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HES4 Gene
CRISPR Products
-
OriGene CRISPR knockouts for HES4
-
Applied Biological Materials CRISPR for HES4
-
Santa Cruz Biotechnology (SCBT) CRISPR for HES4
- GenScript: Design CRISPR guide RNA sequences for HES4
miRNA Products
- Search ViGene Biosciences for HES4
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HES4
- Browse OriGene Inhibitory RNA Products For HES4
-
ViGene Biosciences ready-to-package AAV shRNAs for HES4 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for HES4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HES4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||
| SP2: | - | - | |||||||||||
| SP3: |
Expression for HES4 Gene
NURSA nuclear receptor signaling pathways regulating expression of HES4 Gene:
HES4SOURCE GeneReport for Unigene cluster for HES4 Gene:
Hs.154029Evidence on tissue expression from TISSUES for HES4 Gene
- Kidney(4.1)
Primer Products
-
OriGene qPCR primer pairs for HES4
-
OriGene qPCR primer pairs and template standards for HES4
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HES4 Gene
Orthologs for HES4 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| dog (Canis familiaris) |
Mammalia | HES4 35 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | HES4 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | HES4 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
ManyToMany | |
| chicken (Gallus gallus) |
Aves | -- 35 |
|
ManyToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
ManyToMany | |
| zebrafish (Danio rerio) |
Actinopterygii | her6 35 |
|
ManyToMany | |
| fruit fly (Drosophila melanogaster) |
Insecta | h 35 |
|
ManyToMany | |
| dpn 35 |
|
ManyToMany | |||
| Side 35 |
|
ManyToMany |
- Species where no ortholog for HES4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for HES4 Gene
Variants for HES4 Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000288620 | -- | 998,942(+) | AAGAA(A/G)GAAAA | downstream-variant-500B | |
| rs1000627427 | -- | 999,719(+) | ATGAG(A/G)GTTTT | intron-variant, reference, synonymous-codon | |
| rs1001256418 | -- | 1,000,738(+) | GCGGC(C/G)GGGTC | upstream-variant-2KB, utr-variant-5-prime | |
| rs1001724786 | -- | 1,002,205(+) | TTTGT(A/G)GAGAT | upstream-variant-2KB | |
| rs1003313473 | -- | 1,001,951(+) | CCCCG(C/T)CCCGC | upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv2n67 | CNV | gain | 20364138 |
| dgv5n100 | CNV | gain | 25217958 |
| esv2762302 | CNV | gain | 21179565 |
| nsv1013524 | CNV | gain | 25217958 |
| nsv10161 | CNV | gain+loss | 18304495 |
| nsv1160644 | CNV | deletion | 26073780 |
| nsv428334 | CNV | gain | 18775914 |
| nsv482937 | CNV | loss | 15286789 |
| nsv517709 | CNV | gain+loss | 19592680 |
| nsv544895 | CNV | loss | 21841781 |
| nsv827252 | CNV | gain | 20364138 |
| nsv832980 | CNV | gain | 17160897 |
| nsv950451 | CNV | deletion | 24416366 |
Gene Damage Index Score:
7.83;
83.50% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HES4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HES4
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HES4 Gene
Disorders for HES4 Gene
Relevant External Links for HES4
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- HES4
No disorders were found for HES4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HES4 Gene
Publications for HES4 Gene
- Hes7: a bHLH-type repressor gene regulated by Notch and expressed in the presomitic mesoderm. (PMID: 11260262) Bessho Y. … Kageyama R. (Genes Cells 2001) 2 3 4 64
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
- Identification and characterization of human HES2, HES3, and HES5 genes in silico. (PMID: 15254753) Katoh M. … Katoh M. (Int. J. Oncol. 2004) 2 3 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Novel basic helix-loop-helix transcription factor hes4 antagonizes the function of twist-1 to regulate lineage commitment of bone marrow stromal/stem cells. (PMID: 25579220) Cakouros D. … Gronthos S. (Stem Cells Dev. 2015) 3 64
Products for HES4 Gene
- R&D Systems Antibodies for HES4 (HES-4)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
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- Browse Cell Culture Products
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- Browse Proteome Profiler Antibody Arrays
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- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for HES4
- Search Origene for MassSpec and Protein Over-expression Lysates for HES4
- Origene Custom Protein Services for HES4
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for HES4
- Browse OriGene Inhibitory RNA Products For HES4
- OriGene qPCR primer pairs and template standards for HES4
- OriGene qPCR primer pairs for HES4
- OriGene CRISPR knockouts for HES4
- OriGene ORF clones in human for HES4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HES4
- GenScript: Next-day shipping of latest version cDNA ORF clones for HES4 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for HES4
- GenScript Custom Assay Services for HES4
- GenScript Custom overexpressing Cell Line Services for HES4
- GenScript: Design CRISPR guide RNA sequences for HES4
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for HES4
- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for HES4
- Novus Biologicals proteins and lysates for HES4
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for HES4
- Abcam proteins for HES4
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- Browse Antibodies at Cloud-Clone Corp.
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- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for HES4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online Antibodies for HES4: See all 36
- Search antibodies-online for kits
- antibodies-online Proteins for HES4: See all 3
- Search antibodies-online for peptides
- GeneTex HES4 antibody for HES4
- Search GeneTex for Proteins for HES4
- ViGene Biosciences adenoviral particle packaged cDNA for HES4 gene
- ViGene Biosciences lentiviral particle packaged cDNA for HES4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for HES4 gene
- Search ViGene Biosciences for HES4
- Santa Cruz Biotechnology (SCBT) Antibodies for HES4
- Search Santa Cruz Biotechnology (SCBT) for HES4 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HES4
- Horizon Cell Lines for HES4
- Cyagen custom Knockout/knockin (KOKI) mouse models for HES4
- VectorBuilder custom plasmid, inducible vectors for HES4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HES4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HES4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus Biologicals
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer
- (156) abm
- (157) CrownBio