Aliases for HES4 Gene
Aliases for HES4 Gene
External Ids for HES4 Gene
- HGNC: 24149
- Entrez Gene: 57801
- Ensembl: ENSG00000188290
- OMIM: 608060
- UniProtKB: Q9HCC6
Previous GeneCards Identifiers for HES4 Gene
- GC01M000974
- GC01M000924
- GC01M000206
Summaries for HES4 Gene
GeneCards Summary for HES4 Gene
HES4 (Hes Family BHLH Transcription Factor 4) is a Protein Coding gene. Among its related pathways are PI3K-Akt signaling pathway. Gene Ontology (GO) annotations related to this gene include transcription factor binding and protein dimerization activity. An important paralog of this gene is HES1.
UniProtKB/Swiss-Prot for HES4 Gene
-
Transcriptional repressor. Binds DNA on N-box motifs: 5-CACNAG-3 (By similarity).
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HES4 Gene
Genomics for HES4 Gene
GeneHancer (GH) Regulatory Elements for HES4 Gene
Regulatory Element Products
Genomic Locations for HES4 Gene
- chr1:998,962-1,001,285
- (GRCh38/hg38)
- Size:
- 2,324 bases
- Orientation:
- Minus strand
- chr1:934,342-935,552
- (GRCh37/hg19)
Genomic View for HES4 Gene
- Cytogenetic band:
-
- 1p36.33 by Ensembl
- 1p36.33 by Entrez Gene
- 1p36.33 by HGNC


RefSeq DNA sequence for HES4 Gene
Proteins for HES4 Gene
-
Protein details for HES4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9HCC6-HES4_HUMAN
- Recommended name:
- Transcription factor HES-4
- Protein Accession:
- Q9HCC6
- Q5SVA5
Protein attributes for HES4 Gene
- Size:
- 221 amino acids
- Molecular mass:
- 23523 Da
- Quaternary structure:
-
- Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family.
Post-translational modifications for HES4 Gene
Other Protein References for HES4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for HES4 (HES-4)
- Novus Biologicals Antibodies for HES4
-
Abcam antibodies for HES4
- Invitrogen Antibodies for HES4
- GeneTex HES4 antibody for HES4
-
Santa Cruz Biotechnology (SCBT) Antibodies for HES4
Protein Products
-
OriGene Purified Proteins for HES4
- Search Origene for MassSpec and Protein Over-expression Lysates for HES4
- Origene Custom Protein Services for HES4
- antibodies-online: Search results for 3 available HES4 Proteins ranked by validation data
- Compare Top HES4 Proteins
-
Quality Products:
- Search GeneTex for Proteins for HES4
-
Abcam proteins for HES4
Assay Products
- antibodies-online: Search results for available HES4 related products ranked by validation data
No data available for DME Specific Peptides for HES4 Gene
Domains & Families for HES4 Gene
Gene Families for HES4 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for HES4 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for HES4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9HCC6UniProtKB/Swiss-Prot:
HES4_HUMAN :- Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).
- Domain:
-
- Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).
- The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins.
Function for HES4 Gene
Molecular function for HES4 Gene
- UniProtKB/Swiss-Prot Function:
- Transcriptional repressor. Binds DNA on N-box motifs: 5-CACNAG-3 (By similarity).
Phenotypes From GWAS Catalog for HES4 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003677 | DNA binding | IEA | -- |
GO:0008134 | transcription factor binding | NAS | 17611704 |
GO:0046983 | protein dimerization activity | IEA | -- |
Phenotypes for HES4 Gene
- GenomeRNAi human phenotypes for HES4:
-
- Increased vaccinia virus (VACV) infection
- Decreased viability
- shRNA abundance <= 50%
- Increased transferrin (TF) endocytosis
- Decreased shRNA abundance (Z-score < -2)
- Decreased IL-8 secretion
- Increased shRNA abundance (Z-score > 2)
- Synthetic lethal with vaccinia virus (VACV) infection
- Decreased Hepatitis C virus replication
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for HES4
-
-
ViGene Biosciences lentiviral particle packaged cDNA for HES4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HES4 gene
- Search ViGene Biosciences for HES4
CRISPR Products
-
OriGene CRISPR knockouts for HES4
- genomics-online: gRNA clones - Search results for 43 available HES4 gene related products
- Overview of 43 available HES4 gene related products
- Applied Biological Materials CRISPR for HES4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for HES4
- GenScript: Design CRISPR guide RNA sequences for HES4
miRNA for HES4 Gene
- miRTarBase miRNAs that target HES4
-
- hsa-mir-423-5p (MIRT038130)
- hsa-mir-149-5p (MIRT045541)
- hsa-mir-6720-5p (MIRT453146)
- hsa-mir-6512-3p (MIRT453147)
- hsa-mir-5581-5p (MIRT453148)
- hsa-mir-4297 (MIRT453149)
- hsa-mir-6880-3p (MIRT453150)
- hsa-mir-4699-5p (MIRT453151)
- hsa-mir-4530 (MIRT453152)
- hsa-mir-338-3p (MIRT453153)
- hsa-mir-3065-3p (MIRT453154)
- hsa-mir-181d-3p (MIRT453155)
- hsa-mir-4314 (MIRT486735)
miRNA Products
- Search ViGene Biosciences for HES4
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for HES4
- Browse OriGene Inhibitory RNA Products For HES4
- genomics-online: shRNA clones - Search results for 43 available HES4 gene related products
- Overview of 43 available HES4 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for HES4 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for HES4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HES4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for HES4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for HES4
-
ViGene Biosciences adenoviral particle packaged cDNA for HES4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HES4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HES4 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HES4 Gene
Localization for HES4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HES4 Gene
- Nucleus.
- Cytosol (2)
- Nucleoplasm (2)
- Vesicles (2)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA | -- |
Pathways & Interactions for HES4 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | PI3K-Akt signaling pathway |
Pathways by source for HES4 Gene
1 KEGG pathway for HES4 Gene
Interacting Proteins for HES4 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006351 | transcription, DNA-templated | IEA | -- |
GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
GO:0007275 | multicellular organism development | IEA | -- |
GO:0007399 | nervous system development | IEA | -- |
GO:0030154 | cell differentiation | IEA | -- |
No data available for SIGNOR curated interactions for HES4 Gene
Transcripts for HES4 Gene
mRNA/cDNA for HES4 Gene
- (3) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (65) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HES4 Gene
CRISPR Products
-
OriGene CRISPR knockouts for HES4
- genomics-online: gRNA clones - Search results for 43 available HES4 gene related products
- Overview of 43 available HES4 gene related products
- Applied Biological Materials CRISPR for HES4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for HES4
- GenScript: Design CRISPR guide RNA sequences for HES4
miRNA Products
- Search ViGene Biosciences for HES4
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for HES4
- Browse OriGene Inhibitory RNA Products For HES4
- genomics-online: shRNA clones - Search results for 43 available HES4 gene related products
- Overview of 43 available HES4 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for HES4 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for HES4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HES4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for HES4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||||
SP2: | - | - | |||||||||||
SP3: |
Expression for HES4 Gene
NURSA nuclear receptor signaling pathways regulating expression of HES4 Gene:
HES4SOURCE GeneReport for Unigene cluster for HES4 Gene:
Hs.154029Evidence on tissue expression from TISSUES for HES4 Gene
- Kidney(4.1)
Primer Products
-
OriGene qPCR primer pairs for HES4
-
OriGene qPCR primer pairs and template standards for HES4
- genomics-online: primer clones - Search results for 43 available HES4 gene related products
- Overview of 43 available HES4 gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HES4 Gene
Orthologs for HES4 Gene
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | -- 34 |
|
OneToMany | |
-- 34 |
|
OneToMany | |||
dog (Canis familiaris) |
Mammalia | HES4 34 |
|
OneToOne | |
cow (Bos Taurus) |
Mammalia | HES4 34 |
|
OneToOne | |
oppossum (Monodelphis domestica) |
Mammalia | HES4 34 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
ManyToMany | |
chicken (Gallus gallus) |
Aves | -- 34 |
|
ManyToMany | |
lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
ManyToMany | |
zebrafish (Danio rerio) |
Actinopterygii | her6 34 |
|
ManyToMany | |
fruit fly (Drosophila melanogaster) |
Insecta | h 34 |
|
ManyToMany | |
dpn 34 |
|
ManyToMany | |||
Side 34 |
|
ManyToMany |
- Species where no ortholog for HES4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for HES4 Gene
(4) SIMAP similar genes for HES4 Gene using alignment to 3 proteins:
Variants for HES4 Gene
SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000288620 | -- | 998,942(-) | A/G | downstream_transcript_variant | |
rs1000627427 | -- | 999,719(-) | G/A/T | coding_sequence_variant, intron_variant, synonymous_variant | |
rs1001256418 | -- | 1,000,738(-) | C/G | 5_prime_UTR_variant, genic_upstream_transcript_variant, upstream_transcript_variant | |
rs1001724786 | -- | 1,002,205(-) | A/G | upstream_transcript_variant | |
rs1003313473 | -- | 1,001,951(-) | T/C | upstream_transcript_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv2n67 | CNV | gain | 20364138 |
dgv5n100 | CNV | gain | 25217958 |
esv2762302 | CNV | gain | 21179565 |
nsv1013524 | CNV | gain | 25217958 |
nsv10161 | CNV | gain+loss | 18304495 |
nsv1160644 | CNV | deletion | 26073780 |
nsv428334 | CNV | gain | 18775914 |
nsv482937 | CNV | loss | 15286789 |
nsv517709 | CNV | gain+loss | 19592680 |
nsv544895 | CNV | loss | 21841781 |
nsv827252 | CNV | gain | 20364138 |
nsv832980 | CNV | gain | 17160897 |
nsv950451 | CNV | deletion | 24416366 |
Additional Variant Information for HES4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HES4
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HES4 Gene
Disorders for HES4 Gene
Additional Disease Information for HES4
No disorders were found for HES4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HES4 Gene
Publications for HES4 Gene
- Hes7: a bHLH-type repressor gene regulated by Notch and expressed in the presomitic mesoderm. (PMID: 11260262) Bessho Y … Kageyama R (Genes to cells : devoted to molecular & cellular mechanisms 2001) 2 3 4 58
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 58
- Identification and characterization of human HES2, HES3, and HES5 genes in silico. (PMID: 15254753) Katoh M … Katoh M (International journal of oncology 2004) 2 3 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Hes4: A potential prognostic biomarker for newly diagnosed patients with high-grade osteosarcoma. (PMID: 27786411) McManus M … Schadler K (Pediatric blood & cancer 2017) 3 58
Products for HES4 Gene
- R&D Systems Antibodies for HES4 (HES-4)
- Browse R&D Systems for Human Recombinant Proteins
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- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for HES4
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- OriGene qPCR primer pairs and template standards for HES4
- OriGene qPCR primer pairs for HES4
- OriGene CRISPR knockouts for HES4
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- GenScript: Design CRISPR guide RNA sequences for HES4
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- Novus Biologicals
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- Abcam antibodies for HES4
- Abcam proteins for HES4
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- Cloud-Clone Corp. disease models service
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- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for HES4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for HES4
- VectorBuilder custom plasmid, inducible vectors for HES4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HES4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 41 available HES4 Antibodies ranked by validation data
- Compare Top HES4 Antibodies
- antibodies-online: Search results for available HES4 related products ranked by validation data
- antibodies-online: Search results for 3 available HES4 Proteins ranked by validation data
- Compare Top HES4 Proteins
- Quality Products:
- GeneTex HES4 antibody for HES4
- Search GeneTex for Proteins for HES4
- ViGene Biosciences adenoviral particle packaged cDNA for HES4 gene
- ViGene Biosciences lentiviral particle packaged cDNA for HES4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for HES4 gene
- Search ViGene Biosciences for HES4
- Santa Cruz Biotechnology (SCBT) Antibodies for HES4
- Search Santa Cruz Biotechnology (SCBT) for HES4 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HES4
- Horizon Cell Lines for HES4
- genomics-online: cdna clones - Search results for 43 available HES4 gene related products
- Overview of 43 available HES4 gene related products
- orf clones - Search results for 43 available HES4 gene related products
- Overview of 43 available HES4 gene related products
- genomics-online: gRNA clones - Search results for 43 available HES4 gene related products
- Overview of 43 available HES4 gene related products
- genomics-online: primer clones - Search results for 43 available HES4 gene related products
- Overview of 43 available HES4 gene related products
- genomics-online: shRNA clones - Search results for 43 available HES4 gene related products
- Overview of 43 available HES4 gene related products
Sources for HES4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew