HES2 Gene
protein-coding GIFtS: 50
GCID: GC01M006406
|
|
hairy and enhancer of split 2 (Drosophila)
| |
Aliases
for HES2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Hairy And Enhancer Of Split 2 (Drosophila)1 2 | | BHLHb401 | | Class B Basic Helix-Loop-Helix Protein 402 3 | | Transcription Factor HES-22 | | BHLHB403 | | Hairy And Enhancer Of Split 23 |
Export aliases for HES2 gene to outside databasesPrevious GC identifers: GC01M006049 GC01M006281 GC01U900784 GC01M006183 GC01M005622 |
Summaries
for HES2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: HES2_HUMAN, Q9Y543Function: Transcriptional repressor of genes that require a bHLH protein for their transcription (By similarity)
|
Genomic Views
for HES2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_021937.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HES2 gene promoter:
AhR LCR-F1 Arnt E47 N-Myc Max AREB6 Pax-4a c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for HES2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HES2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36.31 Ensembl cytogenetic band: 1p36.31 HGNC cytogenetic band: 1p36.31HES2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M006406: view genomic region
(about GC identifiers)
Start:
|
6,472,478 bp from pter |
End:
|
6,484,730 bp from pter |
Size:
|
12,253 bases |
Orientation:
|
minus strand |
|
Proteins
for HES2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: HES2_HUMAN, Q9Y543 (See
protein sequence)Recommended Name: Transcription factor HES-2 Size: 173 amino acids; 18470 Da
Subunit: Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family(By similarity)
Subcellular location: Nucleus (By similarity)
Secondary accessions: A2RTZ9 Q96EN4 Q9Y542Alternative splicing: 2 isoforms: Q9Y543-1 Q9Y543-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for HES2: NX_Q9Y543
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y543
HES2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_061962.2
ENSEMBL proteins: ENSP00000367068 ENSP00000367067 ENSP00000367065 ENSP00000465248 ENSP00000465270
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
HES2 for ontologies About GeneDecksing
HES2 Antibody Products:
Assay Products for HES2: |
Protein
Domains /
Families
for HES2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HES2 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y543ProtoNet protein and cluster: Q9Y543 2 Blocks protein families: IPB001092 Basic helix-loop-helix dimerization domain bHLH IPB003650 Orange
UniProtKB/Swiss-Prot: HES2_HUMAN, Q9Y543Domain: Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box(CACNAG), rather than the canonical E-box (CANNTG)Domain: The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLEfamily members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins (Bysimilarity)Similarity: Contains 1 bHLH (basic helix-loop-helix) domainSimilarity: Contains 1 Orange domain |
Function
for HES2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: HES2_HUMAN, Q9Y543Function: Transcriptional repressor of genes that require a bHLH protein for their transcription (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HES2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HES2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: HES2 (NM_019089) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HES2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HES2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HES2 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
HES2 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for HES2:
|
Pathways & Interactions
for HES2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HES2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/7 Interacting proteins for HES2 (ENSP000003670654) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0045892 | negative regulation of transcription, DNA-dependent |
IEA | -- |
HES2 for ontologies About GeneDecksing
|
Drugs & Compounds
for HES2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for HES2
Search CenterWatch for drugs/clinical trials and news about HES2
|
Transcripts
for HES2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HES2 gene: NM_019089.4 Unigene Cluster for HES2: Hairy and enhancer of split 2 (Drosophila) Hs.118727 [show with all ESTs]Unigene Representative Sequence: NM_0190896 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000377837(uc001amw.3) ENST00000377836 ENST00000471190 ENST00000377834(uc001amx.3)
ENST00000487437 ENST00000489730
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HES2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HES2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: HES2 (NM_019089) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HES2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HES2 |
Additional cDNA sequence: AK023754.1 AK091122.1 BC012091.1 BC132698.1 BC136963.1 BC142687.1 4 DOTS entries: DT.410244 DT.70100638 DT.100745863 DT.100829461 24/52 AceView cDNA sequences (see all 52): AW516444 AK091122 C00167 BX108718 BU729177 BM998306 AA339789 BC012091 AA515208 AA127465 AA702466 BX396798 AA878200 BI223008 BF354381 BE904050 AI333927 AL602811 AI738963 BM695934 AI275093 BG470458 AK023754 CB961786
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for HES2 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6a | · | 6b |
|---|
|
| SP1: | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | - | | - | | | | | | - | | - | | - | | - | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for HES2
|
Expression
for HES2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HES2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTCGTGGGAA
About this image
See HES2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HES2
SOURCE GeneReport for Unigene cluster: Hs.118727
UniProtKB/Swiss-Prot: HES2_HUMAN, Q9Y543Tissue specificity: Expressed in placenta, pancreatic cancer, colon cancer with RER, cervical cancer, and in head andneck tumors
SABiosciences Custom PCR Arrays for HES2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HES2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HES2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HES2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HES2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HES2 |
Orthologs
for HES2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for HES2 gene from 2/12 species (see all 12) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
hes2.16hes2.26 |
hairy and enhancer of split 2.2 |
36(a)34(a) |
1 ↔ many1 ↔ many |
8(49077472-49082398) 8(49052584-49053873) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Side6 |
similar to Deadpan |
12(a) |
1 ↔ 1 |
2L(19027712-19030787) |
ENSEMBL Gene Tree for HES2 (if available)
TreeFam Gene Tree for HES2 (if available) |
Paralogs
for HES2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for HES2 gene
- HEYL2 HES42 HES62 HELT2 HEY22 HES72 HES32 HEY12
- HES52 HES12
3 SIMAP similar genes for HES2 using alignment to 3 protein entries: HES2_HUMAN (see all proteins):HES1 HES6 HES5
HES2 for paralogs About GeneDecksing
|
Genomic Variants
for HES2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HES2 (6472478 - 6484730 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for HES2
2 CNVs: 70912 53700 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HES2 |
|
Disorders
/ Diseases
for HES2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HES2 for disorders About GeneDecksing
OMIM gene information: 609970
OMIM disorders: --
6  diseases for HES2: About MalaCardscervical cancer cervicitis colon cancer pancreatic cancer
pancreatitis neuronitis
Export disorders for HES2 gene to outside databases
|
Publications
for HES2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HES2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with HES2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and characterization of human HES2, HES3, and HES5 genes in silico. (PubMed id 15254753)1, 2, 3, 9 Katoh M. and Katoh M. (2004)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer. (PubMed id 17611704)1, 9 Katoh M. and Katoh M. (2007)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Structure, chromosomal locus, and promoter of mouse Hes2 gene, a homologue of Drosophila hairy and Enhancer of split. (PubMed id 9570950)1 Nishimura M....Kageyama R. (1998)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
|
External Searches for HES2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HES2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HES2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HES2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for HES2 gene:
Search GeneIP for patents involving HES2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HES2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for HES2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HES2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HES2 | | | OriGene Protein Over-expression Lysate for HES2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HES2 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HES2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HES2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for HES2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HES2 | | OriGene Custom Protein Services for HES2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HES2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HES2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HES2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HES2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HES2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HES2 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for HES2 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | HES2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HES2 |
|  |  |  | | | | ThermoFisher Antibodies for HES2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HES2 |
|
|
|
|
