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Aliases for HERC2P3 Gene

Aliases for HERC2P3 Gene

  • Hect Domain And RLD 2 Pseudogene 3 2 3
  • D15F37S4 3

External Ids for HERC2P3 Gene

Summaries for HERC2P3 Gene

GeneCards Summary for HERC2P3 Gene

HERC2P3 (Hect Domain And RLD 2 Pseudogene 3) is a Pseudogene. GO annotations related to this gene include ubiquitin-protein transferase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HERC2P3 Gene

Genomics for HERC2P3 Gene

Genomic Location for HERC2P3 Gene

Start:
20,379,495 bp from pter
End:
20,506,180 bp from pter
Size:
126,686 bases
Orientation:
Minus strand

Genomic View for HERC2P3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for HERC2P3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HERC2P3 Gene

No data available for Regulatory Elements for HERC2P3 Gene

Proteins for HERC2P3 Gene

  • Protein details for HERC2P3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BVR0-HRC23_HUMAN
    Recommended name:
    Putative HERC2-like protein 3
    Protein Accession:
    Q9BVR0
    Secondary Accessions:

    Protein attributes for HERC2P3 Gene

    Size:
    1158 amino acids
    Molecular mass:
    128943 Da
    Quaternary structure:
    No Data Available

neXtProt entry for HERC2P3 Gene

Proteomics data for HERC2P3 Gene at MOPED

Post-translational modifications for HERC2P3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HERC2P3 Gene

Domains for HERC2P3 Gene

Protein Domains for HERC2P3 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for HERC2P3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BVR0

UniProtKB/Swiss-Prot:

HRC23_HUMAN
Domain:
  • Contains 1 MIB/HERC2 domain.:
    • Q9BVR0
genes like me logo Genes that share domains with HERC2P3: view

No data available for Gene Families for HERC2P3 Gene

Function for HERC2P3 Gene

Molecular function for HERC2P3 Gene

GENATLAS Biochemistry: HECT domain and RLD2,pseudogene 3

Gene Ontology (GO) - Molecular Function for HERC2P3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004842 ubiquitin-protein transferase activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with HERC2P3: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for HERC2P3 Gene

Localization for HERC2P3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HERC2P3 Gene

Pathways for HERC2P3 Gene

SuperPathways for HERC2P3 Gene

No Data Available

Interacting Proteins for HERC2P3 Gene

Gene Ontology (GO) - Biological Process for HERC2P3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016567 protein ubiquitination IEA --
genes like me logo Genes that share ontologies with HERC2P3: view

No data available for Pathways by source for HERC2P3 Gene

Transcripts for HERC2P3 Gene

Unigene Clusters for HERC2P3 Gene

Hect domain and RLD 2 pseudogene 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HERC2P3 Gene

No ASD Table

Relevant External Links for HERC2P3 Gene

GeneLoc Exon Structure for
HERC2P3
ECgene alternative splicing isoforms for
HERC2P3

Expression for HERC2P3 Gene

mRNA expression in normal human tissues for HERC2P3 Gene

mRNA differential expression in normal tissues according to GTEx for HERC2P3 Gene

This gene is overexpressed in Brain - Substantia nigra (4.2).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for HERC2P3 Gene

SOURCE GeneReport for Unigene cluster for HERC2P3 Gene Hs.608918

genes like me logo Genes that share expressions with HERC2P3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for HERC2P3 Gene

Orthologs for HERC2P3 Gene

Evolution for HERC2P3 Gene

ENSEMBL:
Gene Tree for HERC2P3 (if available)
TreeFam:
Gene Tree for HERC2P3 (if available)

No data available for Orthologs for HERC2P3 Gene

Paralogs for HERC2P3 Gene

Selected SIMAP similar genes for HERC2P3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with HERC2P3: view

No data available for Paralogs for HERC2P3 Gene

Variants for HERC2P3 Gene

Sequence variations from dbSNP and Humsavar for HERC2P3 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs296347 -- 20,466,896(-) tacag(A/G)tgtga intron-variant
rs296353 -- 20,460,771(-) ggctg(A/C)ggcgg intron-variant
rs367043 -- 20,440,992(-) ACATA(C/T)TTAGA intron-variant
rs407297 -- 20,449,263(-) GACTG(A/G)CCTCT intron-variant
rs415516 -- 20,436,725(-) ATGGC(A/G)TATTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for HERC2P3 Gene

Variant ID Type Subtype PubMed ID
esv22518 CNV Gain+Loss 19812545
dgv666e1 CNV Complex 17122850
dgv667e1 CNV Complex 17122850
dgv668e1 CNV Complex 17122850
nsv511040 OTHER Inversion 20534489
dgv669e1 CNV Complex 17122850
dgv672e1 CNV Complex 17122850
nsv428296 CNV Gain+Loss 18775914
dgv91e55 CNV Gain 17911159
dgv92e55 CNV Gain 17911159
dgv93e55 CNV Gain 17911159
dgv95e55 CNV Loss 17911159
dgv96e55 CNV Loss 17911159
nsv9179 CNV Gain+Loss 18304495
dgv2080n71 CNV Gain 21882294
dgv2081n71 CNV Gain 21882294
nsv436198 CNV Deletion 17901297
dgv2082n71 CNV Gain 21882294
nsv7260 OTHER Inversion 18451855
nsv1452 CNV Loss 18451855
dgv43n16 CNV Insertion 17901297
nsv821678 CNV Loss 15273396
dgv675e1 CNV Complex 17122850
dgv676e1 CNV Complex 17122850
dgv677e1 CNV Complex 17122850
dgv678e1 CNV Complex 17122850
dgv2083n71 CNV Gain 21882294
nsv902685 CNV Gain+Loss 21882294
nsv821092 CNV Duplication 20802225
dgv679e1 CNV Complex 17122850
dgv414n67 CNV Gain 20364138
esv33051 CNV Gain+Loss 17666407
dgv2084n71 CNV Gain 21882294
dgv2085n71 CNV Loss 21882294
nsv433426 CNV Gain 18776910
dgv680e1 CNV Complex 17122850
nsv902697 CNV Loss 21882294
dgv415n67 CNV Gain 20364138
essv17110 CNV CNV 17122850
dgv681e1 CNV Complex 17122850
dgv2086n71 CNV Loss 21882294
nsv902704 CNV Gain+Loss 21882294
dgv2087n71 CNV Gain 21882294
dgv2089n71 CNV Gain+Loss 21882294
nsv902715 CNV Gain 21882294
nsv902716 CNV Loss 21882294
nsv902717 CNV Gain 21882294
dgv2090n71 CNV Gain 21882294
nsv819770 CNV Gain 19587683
esv998961 CNV Loss 20482838
dgv417n67 CNV Gain 20364138
dgv682e1 CNV Complex 17122850
esv29956 CNV Loss 18421352
nsv514762 CNV Complex 21397061
dgv2091n71 CNV Gain+Loss 21882294
dgv2092n71 CNV Gain 21882294
esv988919 CNV Loss 20482838
dgv8n14 CNV Loss 18776910
dgv2093n71 CNV Loss 21882294
nsv902731 CNV Gain 21882294
nsv902732 CNV Gain+Loss 21882294
dgv2095n71 CNV Gain+Loss 21882294
esv2751488 CNV Loss 17911159
dgv2096n71 CNV Gain 21882294
nsv902745 CNV Gain 21882294
dgv2097n71 CNV Gain 21882294
nsv902750 CNV Gain 21882294
essv1841 CNV CNV 17122850
nsv902751 CNV Loss 21882294
dgv1n1 OTHER Inversion 15895083
esv6472 CNV Gain 19470904
esv1004259 OTHER Inversion 20482838
nsv832908 CNV Gain 17160897
nsv514763 CNV Complex 21397061
dgv28n68 CNV Gain+Loss 17160897

Relevant External Links for HERC2P3 Gene

HapMap Linkage Disequilibrium report
HERC2P3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HERC2P3 Gene

Disorders for HERC2P3 Gene

No disorders were found for HERC2P3 Gene.

No data available for UniProtKB/Swiss-Prot for HERC2P3 Gene

Publications for HERC2P3 Gene

  1. Expressed copies of the MN7 (D15F37) gene family map close to the common deletion breakpoints in the Prader-Willi/Angelman syndromes. (PMID: 9730612) Buiting K. … Horsthemke B. (Cytogenet. Cell Genet. 1998) 2 3
  2. The ancestral gene for transcribed, low-copy repeats in the Prader- Willi/Angelman region encodes a large protein implicated in protein trafficking, which is deficient in mice with neuromuscular and spermiogenic abnormalities. (PMID: 9949213) Ji Y. … Nicholls R.D. (Hum. Mol. Genet. 1999) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PMID: 23000965) Povlsen L.K. … Choudhary C. (Nat. Cell Biol. 2012) 3

Products for HERC2P3 Gene

Sources for HERC2P3 Gene

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