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HERC2P2 Gene(Pseudogene)

Hect Domain And RLD 2 Pseudogene 2

GCID:
GC15P022494
GIFtS:
21
Genes Participants
UDN Logo

Aliases for HERC2P2 Gene

Aliases for HERC2P2 Gene

  • Hect Domain And RLD 2 Pseudogene 2 2 3 5
  • D15F37S3 3
  • MN7 3

External Ids for HERC2P2 Gene

Previous GeneCards Identifiers for HERC2P2 Gene

  • GC15U990060
  • GC15M020836
  • GC15M023283

Summaries for HERC2P2 Gene

GeneCards Summary for HERC2P2 Gene

HERC2P2 (Hect Domain And RLD 2 Pseudogene 2) is a Pseudogene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HERC2P2 Gene

Genomics for HERC2P2 Gene

Products:

  1. Regulatory Element

Regulatory Elements for HERC2P2 Gene

Enhancers for HERC2P2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15G022494 0.7 ENCODE 0.7 +0.0 9 0.7 CTCF SAP130 L3MBTL2 NRF1 SP2 MNT E2F1 POLR2A ZNF341 GABPB1 HERC2P2 LOC100419579
GH15G022496 0.4 Ensembl 0.7 +2.1 2064 0.6 ZNF175 HERC2P2 LOC100419579
GH15G022526 0.2 Ensembl 0.3 +32.2 32164 0.4 HERC2P2 LOC100419579
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around HERC2P2 on UCSC Golden Path with GeneCards custom track

Promoters for HERC2P2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000073982 263 2201 CTCF SAP130 L3MBTL2 NRF1 NR2F1 POLR2A ZNF341 GABPB1 IKZF1 IKZF2

Transcription factor binding sites by QIAGEN in the HERC2P2 gene promoter:

Genomic Location for HERC2P2 Gene

Chromosome:
15
Start:
22,494,837 bp from pter
End:
22,590,831 bp from pter
Size:
95,995 bases
Orientation:
Plus strand

Genomic View for HERC2P2 Gene

Genes around HERC2P2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HERC2P2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HERC2P2 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for HERC2P2 Gene

Proteins for HERC2P2 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for HERC2P2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HERC2P2 Gene

Domains & Families for HERC2P2 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HERC2P2 Gene

Function for HERC2P2 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Molecular function for HERC2P2 Gene

GENATLAS Biochemistry:
HECT domain and RLD2,pseudogene 2

Phenotypes for HERC2P2 Gene

GenomeRNAi human phenotypes for HERC2P2:
genes like me logo Genes that share phenotypes with HERC2P2: view

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HERC2P2 Gene

Localization for HERC2P2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HERC2P2 Gene

Pathways & Interactions for HERC2P2 Gene

SuperPathways for HERC2P2 Gene

PathCards logo More details on SuperPathways for HERC2P2
No Data Available

Interacting Proteins for HERC2P2 Gene

Gene Ontology (GO) - Biological Process for HERC2P2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HERC2P2 Gene

Drugs & Compounds for HERC2P2 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for HERC2P2 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for HERC2P2 Gene

(13) Additional mRNA sequences :
(247) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HERC2P2 Gene

Hect domain and RLD 2 pseudogene 2:
Representative Sequences:

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for HERC2P2 Gene

No ASD Table

Relevant External Links for HERC2P2 Gene

GeneLoc Exon Structure for
HERC2P2
ECgene alternative splicing isoforms for
HERC2P2

Expression for HERC2P2 Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HERC2P2 Gene

mRNA expression in normal human tissues for HERC2P2 Gene
mRNA expression by BioGPS for HERC2P2 GenemRNA expression by GTEx for HERC2P2 Gene

NURSA nuclear receptor signaling pathways regulating expression of HERC2P2 Gene:

HERC2P2

SOURCE GeneReport for Unigene cluster for HERC2P2 Gene:

Hs.458334
genes like me logo Genes that share expression patterns with HERC2P2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HERC2P2 Gene

Orthologs for HERC2P2 Gene

Evolution for HERC2P2 Gene

ENSEMBL:
Gene Tree for HERC2P2 (if available)
TreeFam:
Gene Tree for HERC2P2 (if available)

No data available for Orthologs for HERC2P2 Gene

Paralogs for HERC2P2 Gene

No data available for Paralogs for HERC2P2 Gene

Variants for HERC2P2 Gene

Sequence variations from dbSNP and Humsavar for HERC2P2 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1000131121 -- 22,539,007(-) TGTAC(A/C)GCACG intron-variant
rs1000153277 -- 22,588,823(-) TGAAT(G/T)TAAAT intron-variant
rs1000183937 -- 22,534,273(-) ACAAA(A/G)CACAT intron-variant
rs1000293972 -- 22,507,254(-) GAGGA(C/G)AGCAG intron-variant
rs1000370743 -- 22,562,703(-) GTGGT(A/G)GTTAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for HERC2P2 Gene

Variant ID Type Subtype PubMed ID
dgv1375e59 CNV duplication 20981092
dgv1376e59 CNV duplication 20981092
dgv1377e59 CNV duplication 20981092
dgv2403n100 CNV gain 25217958
dgv2405n100 CNV gain+loss 25217958
dgv2406n100 CNV gain 25217958
dgv2407n100 CNV gain+loss 25217958
dgv2408n100 CNV loss 25217958
dgv2409n100 CNV loss 25217958
dgv2410n100 CNV gain 25217958
dgv4318n54 CNV gain 21841781
dgv708e212 CNV loss 25503493
dgv709e212 CNV gain 25503493
esv1010587 CNV loss 20482838
esv2474417 CNV loss 19546169
esv28050 CNV gain+loss 19812545
esv3341142 CNV duplication 20981092
esv3361141 CNV duplication 20981092
esv3364198 CNV duplication 20981092
esv3369728 CNV duplication 20981092
esv3371576 CNV duplication 20981092
esv3373959 CNV duplication 20981092
esv3377517 CNV duplication 20981092
esv3382628 CNV duplication 20981092
esv3386077 CNV duplication 20981092
esv3387230 CNV duplication 20981092
esv3388253 CNV duplication 20981092
esv3388685 CNV duplication 20981092
esv3399428 CNV duplication 20981092
esv3419059 CNV duplication 20981092
esv3430595 CNV duplication 20981092
esv3436656 CNV duplication 20981092
esv3437650 CNV duplication 20981092
esv3443704 CNV duplication 20981092
esv3447921 CNV duplication 20981092
esv3569265 CNV gain 25503493
esv3581515 CNV loss 25503493
esv3892626 CNV gain+loss 25118596
nsv1035969 CNV loss 25217958
nsv1040546 CNV gain 25217958
nsv1041383 CNV loss 25217958
nsv1078376 CNV duplication 25765185
nsv1078377 CNV duplication 25765185
nsv1118550 CNV duplication 24896259
nsv1128720 CNV duplication 24896259
nsv1139621 CNV duplication 24896259
nsv1149034 CNV duplication 26484159
nsv1149605 CNV duplication 26484159
nsv1150640 CNV duplication 26484159
nsv433429 CNV gain 18776910
nsv433430 CNV gain 18776910
nsv511042 OTHER inversion 20534489
nsv568235 CNV loss 21841781
nsv832927 CNV gain 17160897
nsv832928 CNV gain 17160897
nsv952567 CNV deletion 24416366
nsv974524 CNV duplication 23825009
nsv974525 CNV duplication 23825009
nsv976985 CNV duplication 23825009
nsv977663 CNV duplication 23825009
nsv977664 CNV duplication 23825009
nsv984018 CNV duplication 23825009

Relevant External Links for HERC2P2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HERC2P2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HERC2P2 Gene

Disorders for HERC2P2 Gene

Relevant External Links for HERC2P2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HERC2P2

No disorders were found for HERC2P2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HERC2P2 Gene

Publications for HERC2P2 Gene

  1. Expressed copies of the MN7 (D15F37) gene family map close to the common deletion breakpoints in the Prader-Willi/Angelman syndromes. (PMID: 9730612) Buiting K. … Horsthemke B. (Cytogenet. Cell Genet. 1998) 2 3 64
  2. Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint. (PMID: 26354767) Bailey M.L. … Hieter P. (Genetics 2015) 3 64
  3. Defining the human deubiquitinating enzyme interaction landscape. (PMID: 19615732) Sowa M.E. … Harper J.W. (Cell 2009) 3 64
  4. Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (PMID: 17043677) Camargo L.M. … Brandon N.J. (Mol. Psychiatry 2007) 3 64
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64

Products for HERC2P2 Gene

Sources for HERC2P2 Gene

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