HERC2P2 Gene

Aliases
for HERC2P2 gene

Previous GC identifers: GC15U990060 GC15M020836

Summaries
for HERC2P2 gene

Genomic Views
for HERC2P2 gene

RefSeq DNA sequence:

NC_000015.9  NC_018926.1  NT_078094.2  

Browse SwitchGear Promoter luciferase reporter plasmids

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HERC2P2

HERC2P2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M023283:  view genomic region     (about GC identifiers)

Proteins
for HERC2P2 gene

Protein Domains /
Families
for HERC2P2 gene

Function
for HERC2P2 gene

Pathways & Interactions
for HERC2P2 gene

Drugs & Compounds
for HERC2P2 gene

Transcripts
for HERC2P2 gene

Unigene Clusters for HERC2P2:

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HERC2P2
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate HERC2P2
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		Browse OriGene 29mer shRNA kits Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HERC2P2

Clone Products:		Browse OriGene untagged/tagged cDNA clones in CMV expression vector OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript Custom all cDNA clones Services for HERC2P2
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for HERC2P2
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat HERC2P2

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HERC2P2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse / rat HERC2P2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HERC2P2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HERC2P2

Additional cDNA sequence: 

24/49 DOTS entries (see all 49):

24/247 AceView cDNA sequences (see all 247):

5/18 Alternative Splicing Database (ASD) splice patterns (SP) for HERC2P2 (see all 18)    About this scheme

ExUns:	1	^	2	^	3a	·	3b	^	4	^	5	^	6a	·	6b	^	7a	·	7b	^	8	^	9a	·	9b	^	10a	·	10b	^	11	^	12a	·	12b	^	13	^	14	^	15a	·	15b	^	16a	·	16b	^	17a	·	17b	·
SP1:													-		-		-																																-
SP2:													-		-		-																																-
SP3:																					-
SP4:
SP5:

ExUns:	17c	^	18a	·	18b	·	18c	·	18d	^	19a	·	19b	·	19c	^	20a	·	20b	·	20c	·	20d	^	21	^	22a	·	22b	·	22c	^	23	^	24	^	25a	·	25b	^	26a	·	26b	^	27	^	28a	·	28b	^	29	^
SP1:																															-						-				-
SP2:																															-						-				-				-
SP3:
SP4:
SP5:																							-

ExUns:	30	^	31	^	32a	·	32b	^	33a	·	33b	^	34	^	35a	·	35b	·	35c	^	36	^	37a	·	37b	·	37c	·	37d
SP1:					-
SP2:					-														-		-		-
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for HERC2P2

Expression
for HERC2P2 gene

HERC2P2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

Stem Cell Differentiation: 1 LifeMap Cell
	Name			Category
	PureStem™ progenitor EN27 (Embryonic Progenitor Cell)
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HERC2P2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse / rat HERC2P2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HERC2P2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HERC2P2

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HERC2P2

Orthologs
for HERC2P2 gene

Paralogs
for HERC2P2 gene

Genomic Variants
for HERC2P2 gene

10/327 NCBI SNPs in HERC2P2 are shown (see all 327)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 15 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs2022162721,2		--	23281943(+)	GATTC-/TATGTCA	1	--	ds5001		0	--	--	--	--
rs1407796141,2		--	23282211(+)	TACTGA/TTTTAA	1	--	ds5001		0	--	--	--	--
rs1500768011,2		--	23282239(+)	TCATCA/GATGCA	1	--	ds5001		0	--	--	--	--
rs2020384911,2		--	23282431(+)	GATAT-/ACAGTCA	1	--	nc-transcript-variant		0	--	--	--	--
rs1886743001,2		--	23282455(+)	ATTAAC/TTGGTT	1	--	nc-transcript-variant		0	--	--	--	--
rs1914236381,2		--	23282486(+)	AATCAA/TGTATG	1	--	nc-transcript-variant		0	--	--	--	--
rs759442891,2	C,	--	23282508(+)	TAAAGA/CAGCAG	1	--	nc-transcript-variant		0	--	--	--	--
rs1871901321,2		--	23282522(+)	AGATGA/GAGCTA	1	--	nc-transcript-variant		0	--	--	--	--
rs2007588311,2		--	23282535(+)	AAAAC-/AAAGAGA	1	--	nc-transcript-variant		0	--	--	--	--
rs1462660641,2		--	23282547(+)	GAAGAA/CTGTTG	1	--	nc-transcript-variant		0	--	--	--	--

HapMap Linkage Disequilibrium report for HERC2P2 (23282265 - 23378259 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 20 variations for HERC2P2
     15/18 CNVs (see all 18): 30674 66729 31987 37594 76830 87488 72187 37627 102046 76834 3070 3951 72184 72185 4879
     2 Indels: 33592 33593

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HERC2P2

DNA2.0 Custom Variant and Variant Library Synthesis for HERC2P2

Disorders / Diseases
for HERC2P2 gene

Publications
for HERC2P2 gene

PubMed articles for HERC2P2 gene integrated from 9 sources: (articles sorted by number of sources associating them with HERC2P2)

Utopia: connect your pdf to the dynamic world of online information

1. Expressed copies of the MN7 (D15F37) gene family map close to the common deletion breakpoints in the Prader-Willi/Angelman syndromes. (PubMed id 9730612)^{1, 3} Buiting K....Horsthemke B. (1998)
2. Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)¹ Sowa M.E....Harper J.W. (2009)
3. Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (PubMed id 17043677)¹ Camargo L.M....Brandon N.J. (2007)
4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
7. The ancestral gene for transcribed, low-copy repeats in the Prader- Willi/Angelman region encodes a large protein implicated in protein trafficking, which is deficient in mice with neuromuscular and spermiogenic abnormalities. (PubMed id 9949213)¹ Ji Y.... Nicholls R.D. (1999)
8. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)¹ Nagase T.... Ohara O. (1997)
9. A putative gene family in 15q11-13 and 16p11.2: possible implications for Prader-Willi and Angelman syndromes. (PubMed id 1608955)¹ Buiting K....Horsthemke B. (1992)
10. (PubMed id 15608161)¹⁰ 

External Searches for HERC2P2 gene

Genome Databases showing HERC2P2 gene

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Products
for HERC2P2 gene