Aliases for HEPACAM Gene
External Ids for HEPACAM Gene
The protein encoded by this gene is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions. The expression of this gene is downregulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene. [provided by RefSeq, Jul 2011]
GeneCards Summary for HEPACAM Gene
HEPACAM (Hepatic And Glial Cell Adhesion Molecule) is a Protein Coding gene. Diseases associated with HEPACAM include megalencephalic leukoencephalopathy with subcortical cysts 2a and megalencephalic leukoencephalopathy with subcortical cysts 2b, remitting, with or without mental retardation. An important paralog of this gene is HEPACAM2.
UniProtKB/Swiss-Prot for HEPACAM Gene
Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation.