Aliases for HENMT1 Gene
External Ids for HENMT1 Gene
Previous HGNC Symbols for HENMT1 Gene
Previous GeneCards Identifiers for HENMT1 Gene
GeneCards Summary for HENMT1 Gene
HENMT1 (HEN1 Methyltransferase Homolog 1) is a Protein Coding gene. Among its related pathways are Mitotic Prophase and PIWI-interacting RNA (piRNA) biogenesis. GO annotations related to this gene include RNA binding and RNA methyltransferase activity.
UniProtKB/Swiss-Prot for HENMT1 Gene
Methyltransferase that adds a 2-O-methyl group at the 3-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis (By similarity).