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HEMGN Gene

protein-coding   GIFtS: 48
GCID: GC09M100689

Hemogen

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
hemogen1 2     Negative Differentiation Regulator Protein2 3
EDAG2 3 5     EDAG-12 3
Erythroid Differentiation-Associated Gene Protein2 3     NDR2 3
Hemopoietic Gene Protein2 3     CT1552

External Ids:    HGNC: 175091   Entrez Gene: 553632   Ensembl: ENSG000001369297   OMIM: 6107155   UniProtKB: Q9BXL53   

Export aliases for HEMGN gene to outside databases

Previous GC identifers: GC09M091514 GC09M092432 GC09M094146 GC09M096068 GC09M097768 GC09M099729 GC09M070290


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for HEMGN Gene:
HEMGN (hemogen) is a protein-coding gene.

UniProtKB/Swiss-Prot: HEMGN_HUMAN, Q9BXL5
Function: Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the
TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the
activation of the nuclear factor-kappa B (NF-kB)

Gene Wiki entry for HEMGN Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NT_008470.20  NC_018920.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the HEMGN gene promoter:
         AREB6   AML1a   FOXJ2 (long isoform)   IRF-7A   FOXJ2   Pax-4a   NF-kappaB   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHEMGN promoter sequence
   Search Chromatin IP Primers for HEMGN

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HEMGN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q22.33   Ensembl cytogenetic band:  9q22.33   HGNC cytogenetic band: 9q22.33

HEMGN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HEMGN gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M100689:  view genomic region     (about GC identifiers)

Start:
100,689,073 bp from pter      End:
100,707,138 bp from pter
Size:
18,066 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: HEMGN_HUMAN, Q9BXL5 (See protein sequence)
Recommended Name: Hemogen  
Size: 484 amino acids; 55341 Da
Developmental stage: Expressed in fetal liver, kidney and brain
Sequence caution: Sequence=AAF67133.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAF71041.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAG35488.1;
Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q6XAR3 Q86XY5 Q9NPC0

Explore the universe of human proteins at neXtProt for HEMGN: NX_Q9BXL5

Explore proteomics data for HEMGN at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HEMGN Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_060907.2  NP_932095.1  

    ENSEMBL proteins: 
     ENSP00000259456  

    HEMGN Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for HEMGN

     
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    antibodies-online antibodies for HEMGN (26 products) 

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    Cloud-Clone Corp. CLIAs for HEMGN
    Search eBioscience for ELISAs for HEMGN 
    antibodies-online kits for HEMGN (10 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q9BXL5


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HEMGN_HUMAN, Q9BXL5
    Function: Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the
    TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the
    activation of the nuclear factor-kappa B (NF-kB)
    Induction: Down-regulated during megakaryocytic differentiation of K562 cells by
    12-O-tetradecanoylphorbol-13-acetate (TPA) (at protein level). Up-regulated in normal PBMCs by mitogens

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with HEMGN           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for HEMGN:
     Increased gamma-H2AX phosphory 

         1 MGI phenotypic allele for Hemgn (no phenotypes)

    Find genes that share phenotypes with HEMGN           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Hemgntm1(KOMP)Vlcg for HEMGN

       genOway: Develop your customized and physiologically relevant rodent model for HEMGN

    miRNA
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    miRTarBase miRNAs that target HEMGN:
    hsa-mir-148b-3p (MIRT019451)

    Block miRNA regulation of human, mouse, rat HEMGN using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HEMGN (see all 11):
    hsa-miR-3163 hsa-miR-181c hsa-miR-181a hsa-miR-551b* hsa-miR-181d hsa-miR-338-5p hsa-miR-493* hsa-miR-3941
    SwitchGear 3'UTR luciferase reporter plasmidHEMGN 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat HEMGN

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    Browse Sino Biological Human cDNA Clones
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    eBioscience FlowRNA Probe Sets ( VA1-10051) for HEMGN 


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HEMGN_HUMAN, Q9BXL5: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol3
    plasma membrane3

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005654nucleoplasm IEA--

    Find genes that share ontologies with HEMGN           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HEMGN
    Interactions:

        Search GeneGlobe Interaction Network for HEMGN

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    Selected Interacting proteins for HEMGN (Q9BXL51, 2 ENSP000002594564) via UniProtKB, MINT, STRING, and/or I2D (see all 40)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NPM1P067481, 2EBI-3916399,EBI-78579 MINT-8373211 MINT-8373408 MINT-8373290 MINT-8373312 MINT-8373326 MINT-8373269 MINT-8373241
    CBX5P459732, ENSP000002098754MINT-7220149 STRING: ENSP00000209875
    CTBP1Q133631, ENSP000002909214EBI-3916399,EBI-908846 STRING: ENSP00000290921
    ACTBP607092MINT-7220149
    CHAF1AQ131112MINT-7220149
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development IEA--
    GO:0030154cell differentiation IEA--
    GO:0045667regulation of osteoblast differentiation IEA--

    Find genes that share ontologies with HEMGN           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HEMGN



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HEMGN gene (2 alternative transcripts): 
    NM_018437.4  NM_197978.2  

    Unigene Cluster for HEMGN:

    Hemogen
    Hs.176626  [show with all ESTs]
    Unigene Representative Sequence: AY244805
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000259456
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat HEMGN using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HEMGN (see all 11):
    hsa-miR-3163 hsa-miR-181c hsa-miR-181a hsa-miR-551b* hsa-miR-181d hsa-miR-338-5p hsa-miR-493* hsa-miR-3941
    SwitchGear 3'UTR luciferase reporter plasmidHEMGN 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat HEMGN
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    GenScript: all cDNA clones in your preferred vector (see all 2): HEMGN (NM_018437)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HEMGN
    Primer
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    OriGene qPCR primer pairs and template standards for HEMGN
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HEMGN
      QuantiTect SYBR Green Assays in human, mouse, rat HEMGN
      QuantiFast Probe-based Assays in human, mouse, rat HEMGN
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    eBioscience FlowRNA Probe Sets ( VA1-10051) for HEMGN 

    Additional mRNA sequence: 

    AF116617.1 AF228713.2 AF306681.1 AF306682.1 AF306683.1 AF322875.1 AK292441.1 AL833094.1 
    AY244805.1 AY255672.1 BC048324.1 

    6 DOTS entries:

    DT.420059  DT.100654530  DT.95272874  DT.121168421  DT.70103439  DT.40277937 

    Selected AceView cDNA sequences (see all 73):

    AF322875 AA676259 AI114455 AA496130 AF306682 BX099803 NM_018437 AY255672 
    BP369905 NM_197978 AF130060 AL597698 AF306683 BX426753 AL833094 BG941050 
    BI825348 AY244805 BI827170 AI248618 BX445350 AF116617 BX506409 AA435626 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for HEMGN (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c · 5d · 5e ^ 6a · 6b
    SP1:              -     -     -     -     -                                                         
    SP2:                                -     -                                                         
    SP3:                                      -                                                         
    SP4:                                      -                                                         
    SP5:                                                                                                


    ECgene alternative splicing isoforms for HEMGN

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HEMGN expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    HEMGN Expression
    About this image


    HEMGN expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Liver (Hepatobiliary System)    fully expand to see all 3 entries
             Hematopoietic Stem Cells Liver Bud
             Liver Lobule
     
     Blood (Cardiovascular System)    fully expand to see all 2 entries
             Hematopoietic Stem Cells Liver Bud
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Muscle Progenitor Cells Mandibular Arch Muscles
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Kidney (Urinary System)
             Metanephric Mesenchyme Cells Metanephric Mesenchyme
    HEMGN Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HEMGN Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.176626

    UniProtKB/Swiss-Prot: HEMGN_HUMAN, Q9BXL5
    Tissue specificity: Expressed in hematopoietic precursor cells, thyroid and spermatids (at protein level).
    Expressed in bone marrow, testis, thymus. Expressed in prostate cancer and ovarian cancer. Also expressed in
    thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells
    (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for HEMGN gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hemgn1 , 5 hemogen1, 5 69.9(n)1
    51.54(a)1
      4 (24.73 cM)5
    939661  NM_053149.21  NP_444379.11 
     463939895 
    chicken
    (Gallus gallus)
    Aves HEMGN6
    hemogen
    31(a)
    1 ↔ 1
    Z(70487737-70492461)
    lizard
    (Anolis carolinensis)
    Reptilia HEMGN6
    hemogen
    39(a)
    1 ↔ 1
    GL343544.1(215994-220919)


    ENSEMBL Gene Tree for HEMGN (if available)
    TreeFam Gene Tree for HEMGN (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HEMGN (see all 405)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs70309071,2
    C,F,A,H--100688577(+) ATTTAC/TCATAT 2 -- int19Minor allele frequency- T:0.19NS EA CSA WA NA 780
    rs1899120061,2
    --100688694(+) CTAGTA/TATATG 2 -- int10--------
    rs1812230971,2
    C--100689026(+) TTAGAC/TAGGTC 2 -- int10--------
    rs1858227621,2
    --100689043(+) CCTCCA/GCAATT 2 -- int10--------
    rs773572031,2
    C--100689107(+) TTGTGA/CACAAA 2 -- ut310--------
    rs1920660441,2
    --100689370(+) TAGGGA/GGGAAA 2 -- ut310--------
    rs772531431,2
    C,F--100689375(+) GGGAAA/TACCAA 2 -- ut311Minor allele frequency- T:0.03WA 118
    rs348257701,2
    C--100689451(+) TACAT-/ACACACA 2 -- ut310--------
    rs721094221,2
    C--100689451(+) TACAT-/ACA   
       CACAC
    ACACA
    2 -- ut310--------
    rs591776581,2
    C--100689452(+) ACACA-/CACACAC 2 -- ut312Minor allele frequency- CA:0.25NA CSA 4

    HapMap Linkage Disequilibrium report for HEMGN (100689073 - 100707138 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for HEMGN:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv893611CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HEMGN
    DNA2.0 Custom Variant and Variant Library Synthesis for HEMGN

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610715    OMIM disorders: --


    Find genes that share disorders with HEMGN           About GenesLikeMe

    Genetic Association Database (GAD): HEMGN
    Human Genome Epidemiology (HuGE) Navigator: HEMGN (2 documents)

    Export disorders for HEMGN gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HEMGN gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with HEMGN)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Alternative promoters and polyadenylation regulate tissue-specific expression of Hemogen isoforms during hematopoiesis and spermatogenesis. (PubMed id 14648837)1, 2, 9 Yang L.V.... Li L. (Dev. Dyn. 2003)
    2. Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae. (PubMed id 19197348)1, 4 Lowe J.K....Friedman J.M. (PLoS Genet. 2009)
    3. FOXE1 association with both isolated cleft lip with or without cleft palate, and isolated cleft palate. (PubMed id 19779022)1, 4 Moreno L.M....Lidral A.C. (Hum. Mol. Genet. 2009)
    4. High expression of EDAG and its significance in AML. (PubMed id 15920494)1, 2 An L.-L....Song Y.-H. (Leukemia 2005)
    5. EDAG regulates the proliferation and differentiation of hematopoietic cells and resists cell apoptosis through the activation of nuclear factor-kappa B. (PubMed id 15332117)1, 2 Li C.Y.... Yang X.M. (Cell Death Differ. 2004)
    6. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Down-regulation of human NDR gene in megakaryocytic differentiation of erythroleukemia K562 cells. (PubMed id 14730214)1, 2 Liu C.-C.... Ch'ang L.-Y. (J. Biomed. Sci. 2004)
    9. Hemogen is a novel nuclear factor specifically expressed in mouse hematopoietic development and its human homologue EDAG maps to chromosome 9q22, a region containing breakpoints of hematological neoplasms. (PubMed id 11404085)1, 2 Yang L.V.... Li L. (Mech. Dev. 2001)
    10. Scanning of novel cancer/testis proteins by human testis proteomic analysis. (PubMed id 23436708)2 Liu M....Sha J. (Proteomics 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55363 HGNC: 17509 AceView: HEMGN Ensembl:ENSG00000136929 euGenes: HUgn55363
    ECgene: HEMGN H-InvDB: HEMGN

    (According to HUGE)
    About This Section

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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for HEMGN Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HEMGN gene:
    Search GeneIP for patents involving HEMGN

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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