Aliases for HELZ Gene
External Ids for HELZ Gene
Previous GeneCards Identifiers for HELZ Gene
HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 [PubMed 10471385]).[supplied by OMIM, Mar 2008]
GeneCards Summary for HELZ Gene
HELZ (Helicase With Zinc Finger) is a Protein Coding gene. Diseases associated with HELZ include palmoplantar keratoderma, nonepidermolytic. GO annotations related to this gene include poly(A) RNA binding and helicase activity. An important paralog of this gene is UPF1.
UniProtKB/Swiss-Prot for HELZ Gene
May act as a helicase that plays a role in RNA metabolism in multiple tissues and organs within the developing embryo.