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HELQ Gene

protein-coding   GIFtS: 50
GCID: GC04M084328

Helicase, POLQ-Like

  Search for HELQ
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Helicase, POLQ-Like1 2     DNA Helicase HEL3082
HEL3082 3 5     Helicase POLQ-Like2
Mus308-Like Helicase2 3     EC 3.6.4.123
POLQ-Like Helicase2 3     EC 3.6.18

External Ids:    HGNC: 185361   Entrez Gene: 1135102   Ensembl: ENSG000001633127   OMIM: 6067695   UniProtKB: Q8TDG43   

Export aliases for HELQ gene to outside databases

Previous GC identifers: GC04M084548 GC04M080071


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HELQ Gene:
HEL308 is a single-stranded DNA-dependent ATPase and DNA helicase (Marini and Wood, 2002 (PubMed
11751861)).(supplied by OMIM, Mar 2008)

GeneCards Summary for HELQ Gene:
HELQ (helicase, POLQ-like) is a protein-coding gene. GO annotations related to this gene include ATP-dependent helicase activity and nucleic acid binding. An important paralog of this gene is SNRNP200.

UniProtKB/Swiss-Prot: HELQ_HUMAN, Q8TDG4
Function: DNA-dependent ATPase and 5' to 3' DNA helicase




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000004.12  NT_016354.20  NC_018915.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the HELQ gene promoter:
         AhR   AML1a   FOXF2   p53   Pax-6   NF-kappaB   GATA-1   Arnt   NF-kappaB2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHELQ promoter sequence
   Search Chromatin IP Primers for HELQ

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HELQ


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.23   Ensembl cytogenetic band:  4q21.23   HGNC cytogenetic band: 4q21.23

HELQ Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HELQ gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M084328:  view genomic region     (about GC identifiers)

Start:
84,328,496 bp from pter      End:
84,377,025 bp from pter
Size:
48,530 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HELQ_HUMAN, Q8TDG4 (See protein sequence)
Recommended Name: Helicase POLQ-like  
Size: 1101 amino acids; 124131 Da
Subunit: Hexamer
Miscellaneous: ATPase activity is strongly stimulated by single-stranded DNA. Presence of ATP and Mg cofactor are
required for helicase activity allowing to unwind duplex oligonucleotides up to 60-70-mer. This helicase activity
is stimulated by replication protein RPA that binds to unwound regions and inhibits re-annealing
Secondary accessions: Q05DF9 Q502W9 Q659B8 Q6ZQX4 Q6ZTS4 Q96EX7
Alternative splicing: 4 isoforms:  Q8TDG4-1   Q8TDG4-2   Q8TDG4-4   Q8TDG4-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for HELQ: NX_Q8TDG4

Explore proteomics data for HELQ at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for HELQ (Q8TDG4)
     NLPARRV  QMIGRAGR 


    See HELQ Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_598375.2  
    ENSEMBL proteins: 
     ENSP00000424186   ENSP00000295488   ENSP00000424539  

    HELQ Human Recombinant Protein Products:

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    Novus Biologicals HELQ Lysate
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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for HELQ

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR027417 P-loop_NTPase
     IPR014001 Helicase_ATP-bd
     IPR001650 Helicase_C

    Graphical View of Domain Structure for InterPro Entry Q8TDG4

    ProtoNet protein and cluster: Q8TDG4

    UniProtKB/Swiss-Prot: HELQ_HUMAN, Q8TDG4
    Similarity: Belongs to the helicase family. SKI2 subfamily
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    Find genes that share domains with HELQ           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HELQ_HUMAN, Q8TDG4
    Function: DNA-dependent ATPase and 5' to 3' DNA helicase
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.121

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0003676nucleic acid binding IEA--
    GO:0004386helicase activity ----
    GO:0005524ATP binding IEA--
    GO:0008026ATP-dependent helicase activity IEA--
         
    Find genes that share ontologies with HELQ           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for HELQ:
     Upregulation of Wnt/beta-caten 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Helq):
     endocrine/exocrine gland  reproductive system  tumorigenesis 

    Find genes that share phenotypes with HELQ           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HELQ
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for HELQ

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HELQ
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HELQ

    miRNA
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    miRTarBase miRNAs that target HELQ:
    hsa-mir-92a-3p (MIRT048983)

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    GenScript: all cDNA clones in your preferred vector: HELQ (NM_133636)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HELQ

    Cell Line
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol2
    cytoskeleton1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--

    Find genes that share ontologies with HELQ           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HELQ
    Interactions:

        Search GeneGlobe Interaction Network for HELQ

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for HELQ (Q8TDG43 ENSP000002954884) via UniProtKB, MINT, STRING, and/or I2D (see all 59)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    POLNQ7Z5Q53, ENSP000003723164I2D: score=1 STRING: ENSP00000372316
    SUMO1P631653, ENSP000003760764I2D: score=1 STRING: ENSP00000376076
    XAB2ENSP000003511374STRING: ENSP00000351137
    BUD31ENSP000002229694STRING: ENSP00000222969
    MFAP1ENSP000002678124STRING: ENSP00000267812
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000724double-strand break repair via homologous recombination IMP19995904

    Find genes that share ontologies with HELQ           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HELQ



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HELQ gene: 
    NM_133636.2  

    Unigene Cluster for HELQ:

    Helicase, POLQ-like
    Hs.480101  [show with all ESTs]
    Unigene Representative Sequence: NM_133636
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000508591 ENST00000295488(uc003hom.3 uc010ikb.3 uc003hol.4 uc010ikc.3 uc003hon.1 uc003hop.1 uc003hoq.1)
    ENST00000512539 ENST00000510985(uc003hoo.1) ENST00000515482 ENST00000440639

    miRNA
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    Predesigned siRNA for gene silencing in human, mouse, rat HELQ
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    GenScript: all cDNA clones in your preferred vector: HELQ (NM_133636)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HELQ
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HELQ
      QuantiTect SYBR Green Assays in human, mouse, rat HELQ
      QuantiFast Probe-based Assays in human, mouse, rat HELQ

    Additional mRNA sequence: 

    AF436845.1 AK126255.1 AK128665.1 AK308395.1 AK312725.1 AL512702.1 BC011863.2 BC015428.1 
    BC065814.1 BC095473.1 BC111502.1 

    8 DOTS entries:

    DT.97838163  DT.70104407  DT.211107  DT.40258640  DT.95123726  DT.121274532  DT.405745  DT.86850986 

    Selected AceView cDNA sequences (see all 84):

    AA625285 AL702311 BI771202 BU686678 AA971008 AW192200 AA769245 AI627810 
    AI025810 AI240831 AL512702 CK000270 AI948732 Z42372 AI276683 AI564470 
    Z38586 AW024327 AI201192 H59461 AA283800 BM972744 BC011863 AW118952 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for HELQ    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^
    SP1:                          -                 -           -                       -                                                                           
    SP2:                                                                                                                                                            
    SP3:                                            -           -     -                 -                                                                           
    SP4:                    -     -                                                                                                                                 
    SP5:                                                                                                                                                            

    ExUns: 18 ^ 19
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for HELQ

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HELQ expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTGTTATTA
    HELQ Expression
    About this image

    HELQ Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HELQ Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.480101
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HELQ

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for HELQ gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Helq1 , 5 helicase, POLQ-like1, 5 79.29(n)1
    78.6(a)1
      5 (48.52 cM)5
    1915781  NM_001081107.11  NP_001074576.11 
     1007621455 
    chicken
    (Gallus gallus)
    Aves HELQ1 helicase, POLQ-like 69.72(n)
    68.82(a)
      422606  XM_420565.2  XP_420565.1 
    lizard
    (Anolis carolinensis)
    Reptilia HELQ6
    helicase, POLQ-like
    62(a)
    1 ↔ 1
    5(43338252-43357290)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia helq1 helicase, POLQ-like 66.77(n)
    66.04(a)
      100485183  XM_002939582.2  XP_002939628.2 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.168902 Transcribed sequence with weak similarity to protein more 75.89(n)    BM005035.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mus3011 mutagen-sensitive 301 50.48(n)
    45.82(a)
      38905  NM_139921.4  NP_648178.1 
    worm
    (Caenorhabditis elegans)
    Secernentea helq-11 helq-1 49.91(n)
    41.2(a)
      175210  NM_001027740.3  NP_001022911.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes BRR26
    RNA-dependent ATPase RNA helicase (DEIH box); requ...
    9(a)
    1 → many
    V(529530-536021) YER172C


    ENSEMBL Gene Tree for HELQ (if available)
    TreeFam Gene Tree for HELQ (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HELQ gene
    SNRNP2002  POLN2  ASCC32  POLQ2  

    Find genes that share paralogs with HELQ           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HELQ (see all 1092)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0426434
    A breast cancer sample4--see VAR_0426432 D N mis40--------
    rs1452092341,2
    --84142843(+) CACATA/GCAGGA 1 -- int10--------
    rs170067911,2
    C,F,H--84142850(+) AGGACG/TTGGAC 1 -- int117Minor allele frequency- N:0.00NA NS EA 2206
    rs571486121,2
    --84142925(+) TAGGAA/GGGAAA 1 -- int10--------
    rs1487218331,2
    --84142954(+) TAGGGA/GTGAGG 1 -- int10--------
    rs1861887991,2
    --84142963(+) GGATGA/CACCTG 1 -- int10--------
    rs1920472011,2
    --84143031(+) TAGTGC/TATTTT 1 -- int10--------
    rs170067921,2
    C,F,H--84143105(+) CTAAGA/GAAAAT 1 -- int115Minor allele frequency- G:0.23NA NS EA WA CSA 782
    rs1423185921,2
    --84143112(+) AAATTA/CTGGGG 1 -- int10--------
    rs170067931,2
    C,F--84143298(+) AGGTAT/AATTCA 1 -- int13Minor allele frequency- A:0.01NA 142

    HapMap Linkage Disequilibrium report for HELQ (84328496 - 84377025 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for HELQ:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2675432CNV Deletion23128226
    nsv509909CNV Loss20534489
    nsv829992CNV Loss17160897
    nsv829994CNV Loss17160897
    nsv879512CNV Gain21882294

    Human Gene Mutation Database (HGMD): HELQ
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HELQ
    DNA2.0 Custom Variant and Variant Library Synthesis for HELQ

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606769    OMIM disorders: --


    Find genes that share disorders with HELQ           About GenesLikeMe

    Genetic Association Database (GAD): HELQ
    Human Genome Epidemiology (HuGE) Navigator: HELQ (0 documents)

    Export disorders for HELQ gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HELQ gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with HELQ)
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    1. A human DNA helicase homologous to the DNA cross-link sensitivity protein Mus308. (PubMed id 11751861)1, 2, 3 Marini F. and Wood R.D. (J. Biol. Chem. 2002)
    2. Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. (PubMed id 22267201)1, 4 Stolk L....Lunetta K.L. (Nat. Genet. 2012)
    3. A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. (PubMed id 21437268)1, 4 McKay J.D....Brennan P. (PLoS Genet. 2011)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    5. Human HEL308 localizes to damaged replication forks and unwinds lagging strand structures. (PubMed id 21398521)1 Tafel A.A....McHugh P.J. (J. Biol. Chem. 2011)
    6. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    7. Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study. (PubMed id 20800603)1 Flachsbart F....Nebel A. (Mutat. Res. 2010)
    8. DNA polymerase POLN participates in cross-link repair and homologous recombination. (PubMed id 19995904)1 Moldovan G.L....D'Andrea A.D. (Mol. Cell. Biol. 2010)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    10. Comprehensive analysis of DNA repair gene variants and risk of meningioma. (PubMed id 18270339)1 Bethke L....Houlston R. (J. Natl. Cancer Inst. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 113510 HGNC: 18536 AceView: HEL308 Ensembl:ENSG00000163312 euGenes: HUgn113510
    ECgene: HELQ H-InvDB: HELQ

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HELQ Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HELQ gene:
    Search GeneIP for patents involving HELQ

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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