Aliases for HECW2 Gene
External Ids for HECW2 Gene
Previous GeneCards Identifiers for HECW2 Gene
GeneCards Summary for HECW2 Gene
HECW2 (HECT, C2 And WW Domain Containing E3 Ubiquitin Protein Ligase 2) is a Protein Coding gene. Among its related pathways are SMAD Signaling Network and Ubiquitin-Proteasome Dependent Proteolysis. GO annotations related to this gene include ligase activity and ubiquitin-protein transferase activity. An important paralog of this gene is AREL1.
UniProtKB/Swiss-Prot for HECW2 Gene
E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.